JP2018522041A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018522041A5 JP2018522041A5 JP2018505476A JP2018505476A JP2018522041A5 JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5 JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5
- Authority
- JP
- Japan
- Prior art keywords
- brachyury
- yeast
- immunotherapy composition
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562200497P | 2015-08-03 | 2015-08-03 | |
| US62/200,497 | 2015-08-03 | ||
| PCT/US2016/044977 WO2017023840A1 (en) | 2015-08-03 | 2016-08-01 | Modified yeast-brachyury immunotherapeutic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522041A JP2018522041A (ja) | 2018-08-09 |
| JP2018522041A5 true JP2018522041A5 (enExample) | 2019-09-12 |
| JP6789283B2 JP6789283B2 (ja) | 2020-11-25 |
Family
ID=56618277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505476A Active JP6789283B2 (ja) | 2015-08-03 | 2016-08-01 | 改変酵母−ブラキュリー免疫療法組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11065313B2 (enExample) |
| EP (1) | EP3331552B1 (enExample) |
| JP (1) | JP6789283B2 (enExample) |
| KR (1) | KR102833272B1 (enExample) |
| CN (1) | CN108348586B (enExample) |
| AU (1) | AU2016303525B2 (enExample) |
| CA (1) | CA2994272C (enExample) |
| HK (1) | HK1249431A1 (enExample) |
| IL (1) | IL257208B (enExample) |
| TW (1) | TWI748957B (enExample) |
| WO (1) | WO2017023840A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1216861A1 (zh) | 2013-03-19 | 2016-12-09 | Globeimmune, Inc. | 基於酵母的脊索瘤免疫療法 |
| KR102409372B1 (ko) * | 2014-04-11 | 2022-06-16 | 글로브이뮨 | 효모 면역 요법 및 타입 i 인터페론 감도 |
| KR20250107975A (ko) | 2015-08-03 | 2025-07-14 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 브라큐리 결실 돌연변이체, 브라큐리 결실 돌연변이체를 인코딩하는 비-효모 벡터, 및 이들의 용도 |
| WO2019222073A1 (en) * | 2018-05-15 | 2019-11-21 | Globeimmune, Inc. | Lysates of recombinant yeast for inducing cellular immune responses |
| WO2020112870A1 (en) | 2018-11-28 | 2020-06-04 | Forty Seven, Inc. | Genetically modified hspcs resistant to ablation regime |
| WO2022187963A1 (en) * | 2021-03-10 | 2022-09-15 | Provincial Health Services Authority | Immunotherapy agents targeting brachyury and methods of using same |
| CA3247904A1 (en) * | 2022-03-08 | 2023-09-14 | Immunitybio, Inc. | YEAST-BASED VACCINE INJECTED INTRATUMORALLY |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5310654A (en) | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
| US5234830A (en) | 1988-02-03 | 1993-08-10 | Suntory Limited | DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region |
| IL95019A0 (en) | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5830463A (en) | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| US5858378A (en) | 1996-05-02 | 1999-01-12 | Galagen, Inc. | Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen |
| DE69820291D1 (de) | 1997-10-10 | 2004-01-15 | Meyer Pharmaceuticals Llc | Krebsimmuntherapie mittels allostimulierten zellen zur sequentiellen implantationsstrategie |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| DE60026584T2 (de) | 2000-04-06 | 2007-03-08 | SEER Pharamaceuticals, LLC, Fairfield | Microbielles wirkstoffabgabesystem |
| US7083787B2 (en) | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
| ES2676503T3 (es) | 2002-12-16 | 2018-07-20 | Globeimmune, Inc. | Vacunas basadas en levadura como inmunoterapia |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US20060009404A1 (en) | 2004-07-09 | 2006-01-12 | Williams Jason R | Tumor ablation in combination with pharmaceutical compositions |
| JP2009500454A (ja) | 2005-07-11 | 2009-01-08 | グローブイミューン， インコーポレイテッド | 標的化治療の変異型を回避する免疫応答を惹起するための組成物および方法 |
| US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| BRPI0706913A2 (pt) | 2006-02-02 | 2011-04-12 | Globeimmune Inc | vacina com base em levedura para induzir uma reação imune |
| CA2647102A1 (en) | 2006-03-27 | 2007-11-22 | Globeimmune, Inc. | Ras mutation and compositions and methods related thereto |
| AU2008214029B2 (en) | 2007-02-02 | 2014-01-30 | Globelmmune, Inc. | Methods for producing yeast-based vaccines |
| EP2125868B1 (en) | 2007-02-28 | 2015-06-10 | The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
| CN101730542A (zh) | 2007-03-19 | 2010-06-09 | 环球免疫公司 | 用于靶向消除癌症靶向疗法的突变逃逸的组合物和方法 |
| WO2009042642A2 (en) * | 2007-09-24 | 2009-04-02 | President And Fellows Of Harvard College | Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| WO2010065626A1 (en) | 2008-12-02 | 2010-06-10 | Globeimmune, Inc. | Genotyping tools, methods and kits |
| US10383924B2 (en) * | 2009-04-17 | 2019-08-20 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| WO2011032119A1 (en) | 2009-09-14 | 2011-03-17 | The Regents Of The University Of Colorado | Modulation of yeast-based immunotherapy products and responses |
| JP2013522302A (ja) | 2010-03-14 | 2013-06-13 | グローブイミューン，インコーポレイテッド | 酵母系免疫療法を使用した感染症の薬理ゲノミクス及び治療反応性ガイド治療 |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| PH12013501683A1 (en) | 2011-02-12 | 2019-07-17 | Globeimmune Inc | Yeast-based therapeutic for chronic hepatitis b infection |
| PT2685995T (pt) | 2011-03-17 | 2017-08-09 | Globeimmune Inc | Composições imunoterapêuticas de levedura-brachyury |
| JP2014523878A (ja) | 2011-06-14 | 2014-09-18 | グローブイミューン，インコーポレイテッド | Ｄ型肝炎ウイルス感染の治療又は予防のための酵母ベースの組成物及び方法 |
| CN104024429B (zh) * | 2011-08-17 | 2019-06-04 | 全球免疫股份有限公司 | 酵母-muc1免疫治疗组合物及其用途 |
| HK1216861A1 (zh) | 2013-03-19 | 2016-12-09 | Globeimmune, Inc. | 基於酵母的脊索瘤免疫療法 |
-
2016
- 2016-08-01 KR KR1020187006157A patent/KR102833272B1/ko active Active
- 2016-08-01 US US15/749,832 patent/US11065313B2/en active Active
- 2016-08-01 HK HK18109071.3A patent/HK1249431A1/zh unknown
- 2016-08-01 WO PCT/US2016/044977 patent/WO2017023840A1/en not_active Ceased
- 2016-08-01 EP EP16750335.8A patent/EP3331552B1/en active Active
- 2016-08-01 CN CN201680056316.XA patent/CN108348586B/zh active Active
- 2016-08-01 TW TW105124349A patent/TWI748957B/zh active
- 2016-08-01 AU AU2016303525A patent/AU2016303525B2/en active Active
- 2016-08-01 JP JP2018505476A patent/JP6789283B2/ja active Active
- 2016-08-01 CA CA2994272A patent/CA2994272C/en active Active
-
2018
- 2018-01-29 IL IL257208A patent/IL257208B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018522041A5 (enExample) | ||
| Zuo et al. | An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade | |
| TWI704226B (zh) | 重組溶瘤病毒組合物及其用途 | |
| JP7564572B2 (ja) | 単離された組換え体腫瘍溶解性ワクシニアウイルスとｎｋ細胞を含む治療薬、その使用およびそれを適用したキット | |
| JP2018535668A5 (enExample) | ||
| JP2018199695A5 (enExample) | ||
| CN101591646B (zh) | 一种治疗人宫颈癌的树突状细胞疫苗 | |
| Francis et al. | Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer | |
| RU2015103758A (ru) | Днк-вакцина для применения у пациентов с раком поджелудочной железы | |
| RU2019132253A (ru) | Новая днк-вакцина, нацеленная на pd-l1, для иммунотерапии рака | |
| JP2020511139A5 (enExample) | ||
| CN108261426A (zh) | 药物组合物及其在治疗肿瘤和/或癌症的药物中的应用 | |
| CN105031630A (zh) | 同时分泌pd-1中和抗体和gm-csf因子的肿瘤细胞疫苗及其制备方法 | |
| Molinelli et al. | Biologic therapy in psoriasis (Part II): efficacy and safety of new treatment targeting IL23/IL-17 pathways | |
| JP2015000064A5 (enExample) | ||
| CN105462975A (zh) | 一种特异性抑制ctgf基因表达的小干扰rna及其应用 | |
| JP2014534262A5 (enExample) | ||
| CN104800204B (zh) | 桑辛素抗肿瘤用途 | |
| CN113425856B (zh) | 一种含有基因修饰的溶瘤病毒的药物组合物及其在治疗癌症的用途 | |
| CN101050470A (zh) | 携带c57bl/6鼠端粒酶逆转录酶的重组腺病毒载体 | |
| CN105462976A (zh) | 一种特异性抑制twist1基因表达的小干扰rna及其应用 | |
| Bakacs | Turning self cancer cells into nonself by viral xenogenization | |
| CN102512662B (zh) | 含有柯萨奇b3病毒2b蛋白中36-83位氨基酸基序的蛋白质及其应用 | |
| Iyer et al. | Molecular insights and promise of oncolytic virus based immunotherapy | |
| CN102559753A (zh) | Il-24和osm双基因共表达重组质粒和重组腺病毒以及应用 |