JP2018522041A5 - - Google Patents
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- Publication number
- JP2018522041A5 JP2018522041A5 JP2018505476A JP2018505476A JP2018522041A5 JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5 JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5
- Authority
- JP
- Japan
- Prior art keywords
- brachyury
- yeast
- immunotherapy composition
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562200497P | 2015-08-03 | 2015-08-03 | |
| US62/200,497 | 2015-08-03 | ||
| PCT/US2016/044977 WO2017023840A1 (en) | 2015-08-03 | 2016-08-01 | Modified yeast-brachyury immunotherapeutic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522041A JP2018522041A (ja) | 2018-08-09 |
| JP2018522041A5 true JP2018522041A5 (enExample) | 2019-09-12 |
| JP6789283B2 JP6789283B2 (ja) | 2020-11-25 |
Family
ID=56618277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505476A Active JP6789283B2 (ja) | 2015-08-03 | 2016-08-01 | 改変酵母−ブラキュリー免疫療法組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11065313B2 (enExample) |
| EP (1) | EP3331552B1 (enExample) |
| JP (1) | JP6789283B2 (enExample) |
| KR (1) | KR102833272B1 (enExample) |
| CN (1) | CN108348586B (enExample) |
| AU (1) | AU2016303525B2 (enExample) |
| CA (1) | CA2994272C (enExample) |
| HK (1) | HK1249431A1 (enExample) |
| IL (1) | IL257208B (enExample) |
| TW (1) | TWI748957B (enExample) |
| WO (1) | WO2017023840A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX374829B (es) | 2013-03-19 | 2025-03-06 | Globeimmune Inc | Composición a base de levadura para usarse para tratar cordoma. |
| CN113419058B (zh) * | 2014-04-11 | 2025-04-01 | 全球免疫股份有限公司 | 基于酵母的免疫疗法和i型干扰素敏感性 |
| AU2016302237B2 (en) * | 2015-08-03 | 2022-08-04 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
| EP3793576A4 (en) * | 2018-05-15 | 2022-04-06 | Globeimmune, Inc. | Lysates of recombinant yeast for inducing cellular immune responses |
| AU2019390394C1 (en) | 2018-11-28 | 2024-11-28 | Forty Seven, LLC | Genetically modified HSPCs resistant to ablation regime |
| WO2022187963A1 (en) * | 2021-03-10 | 2022-09-15 | Provincial Health Services Authority | Immunotherapy agents targeting brachyury and methods of using same |
| AU2023231218A1 (en) | 2022-03-08 | 2024-07-25 | Immunitybio, Inc. | Intratumorally injected yeast vaccine |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5310654A (en) | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
| US5234830A (en) | 1988-02-03 | 1993-08-10 | Suntory Limited | DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region |
| IL95019A0 (en) | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| US5830463A (en) | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5858378A (en) | 1996-05-02 | 1999-01-12 | Galagen, Inc. | Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen |
| AU9589398A (en) | 1997-10-10 | 1999-05-03 | Applied Immunotherapeutics, Inc. | Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| US8153414B2 (en) | 2000-04-06 | 2012-04-10 | Allertein Therapeutics, Llc | Microbial delivery system |
| WO2002039951A2 (en) | 2000-11-15 | 2002-05-23 | Globe Immune, Inc. | Yeast-dentritic cell vaccines and uses thereof |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| KR101241272B1 (ko) | 2002-12-16 | 2013-03-15 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 면역 요법으로서의 효모계 백신 |
| US20060009404A1 (en) | 2004-07-09 | 2006-01-12 | Williams Jason R | Tumor ablation in combination with pharmaceutical compositions |
| SG163572A1 (en) | 2005-07-11 | 2010-08-30 | Globeimmune Inc | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| CA2638815A1 (en) | 2006-02-02 | 2007-08-16 | Globeimmune, Inc. | Yeast-based vaccine for inducing an immune response |
| CA2647102A1 (en) | 2006-03-27 | 2007-11-22 | Globeimmune, Inc. | Ras mutation and compositions and methods related thereto |
| CA2676783C (en) | 2007-02-02 | 2016-04-05 | Globeimmune, Inc. | Improved methods for producing yeast-based vaccines |
| DK2918598T3 (en) | 2007-02-28 | 2019-04-29 | The Govt Of U S A As Represented By The Secretary Of The Dept Of Health And Human Services | Brachyury polypeptides and methods of use |
| BRPI0809247A2 (pt) | 2007-03-19 | 2014-09-09 | Globeimmune Inc | Composições e métodos para a ablação do escape mutacional de terapias marcadas para câncer. |
| WO2009042645A2 (en) * | 2007-09-24 | 2009-04-02 | President And Fellows Of Harvard College | The use of mice predisposed to develop ulcerative colitis and colon cancer to develop metabolic profiles associated with same |
| WO2010033841A1 (en) | 2008-09-19 | 2010-03-25 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis c virus infection |
| WO2010065626A1 (en) | 2008-12-02 | 2010-06-10 | Globeimmune, Inc. | Genotyping tools, methods and kits |
| EP3320915A1 (en) | 2009-04-17 | 2018-05-16 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| WO2011032119A1 (en) | 2009-09-14 | 2011-03-17 | The Regents Of The University Of Colorado | Modulation of yeast-based immunotherapy products and responses |
| JP2013522302A (ja) | 2010-03-14 | 2013-06-13 | グローブイミューン，インコーポレイテッド | 酵母系免疫療法を使用した感染症の薬理ゲノミクス及び治療反応性ガイド治療 |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| EP2651439B1 (en) | 2010-12-17 | 2018-09-19 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| EP3266464A3 (en) | 2011-02-12 | 2018-03-14 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis b infection |
| KR102046449B1 (ko) | 2011-03-17 | 2019-11-19 | 글로브이뮨 | 효모-브라큐리 면역요법 조성물 |
| EA030381B1 (ru) | 2011-06-14 | 2018-07-31 | Глоубиммьюн, Инк. | Иммунотерапевтическая композиция, ее применения и способы лечения или профилактики инфекции, вызванной вирусом гепатита дельта |
| CA2844500C (en) | 2011-08-17 | 2022-05-10 | Globeimmune, Inc. | Yeast-muc1 immunotherapeutic compositions and uses thereof |
| MX374829B (es) | 2013-03-19 | 2025-03-06 | Globeimmune Inc | Composición a base de levadura para usarse para tratar cordoma. |
-
2016
- 2016-08-01 WO PCT/US2016/044977 patent/WO2017023840A1/en not_active Ceased
- 2016-08-01 TW TW105124349A patent/TWI748957B/zh active
- 2016-08-01 CN CN201680056316.XA patent/CN108348586B/zh active Active
- 2016-08-01 HK HK18109071.3A patent/HK1249431A1/zh unknown
- 2016-08-01 KR KR1020187006157A patent/KR102833272B1/ko active Active
- 2016-08-01 AU AU2016303525A patent/AU2016303525B2/en active Active
- 2016-08-01 US US15/749,832 patent/US11065313B2/en active Active
- 2016-08-01 JP JP2018505476A patent/JP6789283B2/ja active Active
- 2016-08-01 EP EP16750335.8A patent/EP3331552B1/en active Active
- 2016-08-01 CA CA2994272A patent/CA2994272C/en active Active
-
2018
- 2018-01-29 IL IL257208A patent/IL257208B/en unknown
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