JP2018522041A5 - - Google Patents
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- Publication number
- JP2018522041A5 JP2018522041A5 JP2018505476A JP2018505476A JP2018522041A5 JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5 JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5
- Authority
- JP
- Japan
- Prior art keywords
- brachyury
- yeast
- immunotherapy composition
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562200497P | 2015-08-03 | 2015-08-03 | |
| US62/200,497 | 2015-08-03 | ||
| PCT/US2016/044977 WO2017023840A1 (en) | 2015-08-03 | 2016-08-01 | Modified yeast-brachyury immunotherapeutic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522041A JP2018522041A (ja) | 2018-08-09 |
| JP2018522041A5 true JP2018522041A5 (enExample) | 2019-09-12 |
| JP6789283B2 JP6789283B2 (ja) | 2020-11-25 |
Family
ID=56618277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505476A Active JP6789283B2 (ja) | 2015-08-03 | 2016-08-01 | 改変酵母−ブラキュリー免疫療法組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11065313B2 (enExample) |
| EP (1) | EP3331552B1 (enExample) |
| JP (1) | JP6789283B2 (enExample) |
| KR (1) | KR102833272B1 (enExample) |
| CN (1) | CN108348586B (enExample) |
| AU (1) | AU2016303525B2 (enExample) |
| CA (1) | CA2994272C (enExample) |
| HK (1) | HK1249431A1 (enExample) |
| IL (1) | IL257208B (enExample) |
| TW (1) | TWI748957B (enExample) |
| WO (1) | WO2017023840A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014186047A1 (en) | 2013-03-19 | 2014-11-20 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
| KR102409372B1 (ko) * | 2014-04-11 | 2022-06-16 | 글로브이뮨 | 효모 면역 요법 및 타입 i 인터페론 감도 |
| CN116196403A (zh) | 2015-08-03 | 2023-06-02 | 美国卫生和人力服务部 | Brachyury缺失突变体、编码该缺失突变体的非酵母载体及其用途 |
| CN119818663A (zh) * | 2018-05-15 | 2025-04-15 | 全球免疫公司 | 用于诱导细胞免疫应答的重组酵母裂解物 |
| AU2019390394C1 (en) | 2018-11-28 | 2024-11-28 | Forty Seven, LLC | Genetically modified HSPCs resistant to ablation regime |
| WO2022187963A1 (en) * | 2021-03-10 | 2022-09-15 | Provincial Health Services Authority | Immunotherapy agents targeting brachyury and methods of using same |
| EP4489774A1 (en) * | 2022-03-08 | 2025-01-15 | ImmunityBio, Inc. | Intratumorally injected yeast vaccine |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5310654A (en) | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
| US5234830A (en) | 1988-02-03 | 1993-08-10 | Suntory Limited | DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region |
| IL95019A0 (en) | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| US5830463A (en) | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5858378A (en) | 1996-05-02 | 1999-01-12 | Galagen, Inc. | Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen |
| DE69820291D1 (de) | 1997-10-10 | 2004-01-15 | Meyer Pharmaceuticals Llc | Krebsimmuntherapie mittels allostimulierten zellen zur sequentiellen implantationsstrategie |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| ES2260078T3 (es) | 2000-04-06 | 2006-11-01 | Seer Pharmaceuticals, Llc. | Sistema de administracion microbiana. |
| US7083787B2 (en) | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
| AU2003301021C1 (en) | 2002-12-16 | 2010-02-18 | Globelmmune, Inc. | Yeast-based vaccines as immunotherapy |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US20060009404A1 (en) | 2004-07-09 | 2006-01-12 | Williams Jason R | Tumor ablation in combination with pharmaceutical compositions |
| US20100034840A1 (en) | 2005-07-11 | 2010-02-11 | David Apelian | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| MX2008009929A (es) | 2006-02-02 | 2008-10-01 | Globeimmune Inc | Vacuna a base de levadura para inducir una respuesta inmune. |
| CN101448848B (zh) | 2006-03-27 | 2013-12-04 | 全球免疫股份有限公司 | Ras突变及其相关组合物和方法 |
| JP5570819B2 (ja) | 2007-02-02 | 2014-08-13 | グローブイミューン，インコーポレイテッド | 酵母を含む組成物および酵母を増殖させる方法 |
| DK2918598T3 (en) | 2007-02-28 | 2019-04-29 | The Govt Of U S A As Represented By The Secretary Of The Dept Of Health And Human Services | Brachyury polypeptides and methods of use |
| EP2134358A1 (en) | 2007-03-19 | 2009-12-23 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| WO2009042642A2 (en) * | 2007-09-24 | 2009-04-02 | President And Fellows Of Harvard College | Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| WO2010065626A1 (en) | 2008-12-02 | 2010-06-10 | Globeimmune, Inc. | Genotyping tools, methods and kits |
| EP2419126B1 (en) * | 2009-04-17 | 2018-01-10 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| JP5913103B2 (ja) | 2009-09-14 | 2016-04-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ | 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法 |
| JP2013522302A (ja) | 2010-03-14 | 2013-06-13 | グローブイミューン，インコーポレイテッド | 酵母系免疫療法を使用した感染症の薬理ゲノミクス及び治療反応性ガイド治療 |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| EP2651439B1 (en) | 2010-12-17 | 2018-09-19 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| AP2013007110A0 (en) | 2011-02-12 | 2013-09-30 | Globeimmune Inc | Yeast-based therapeutic for chronic hepatitis B infection |
| AU2012228937B2 (en) | 2011-03-17 | 2016-11-03 | Globeimmune, Inc. | Yeast-Brachyury immunotherapeutic compositions |
| BR112013032381B1 (pt) | 2011-06-14 | 2021-01-12 | Globeimmune, Inc. | composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta |
| RU2017143985A (ru) * | 2011-08-17 | 2019-02-14 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения |
| WO2014186047A1 (en) | 2013-03-19 | 2014-11-20 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
-
2016
- 2016-08-01 WO PCT/US2016/044977 patent/WO2017023840A1/en not_active Ceased
- 2016-08-01 EP EP16750335.8A patent/EP3331552B1/en active Active
- 2016-08-01 HK HK18109071.3A patent/HK1249431A1/zh unknown
- 2016-08-01 KR KR1020187006157A patent/KR102833272B1/ko active Active
- 2016-08-01 CN CN201680056316.XA patent/CN108348586B/zh active Active
- 2016-08-01 AU AU2016303525A patent/AU2016303525B2/en active Active
- 2016-08-01 JP JP2018505476A patent/JP6789283B2/ja active Active
- 2016-08-01 CA CA2994272A patent/CA2994272C/en active Active
- 2016-08-01 TW TW105124349A patent/TWI748957B/zh active
- 2016-08-01 US US15/749,832 patent/US11065313B2/en active Active
-
2018
- 2018-01-29 IL IL257208A patent/IL257208B/en unknown
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