JP2018520653A - 骨髄腫およびその他のがんの免疫療法において使用するための新規細胞エピトープおよび細胞エピトープ組み合わせ - Google Patents

骨髄腫およびその他のがんの免疫療法において使用するための新規細胞エピトープおよび細胞エピトープ組み合わせ Download PDF

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JP2018520653A
JP2018520653A JP2017560907A JP2017560907A JP2018520653A JP 2018520653 A JP2018520653 A JP 2018520653A JP 2017560907 A JP2017560907 A JP 2017560907A JP 2017560907 A JP2017560907 A JP 2017560907A JP 2018520653 A JP2018520653 A JP 2018520653A
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peptide
cell
cells
seq
cancer
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JP2018520653A5 (cg-RX-API-DMAC7.html
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ランメンゼー，ハンス−ゲオルク
スティッケル，ユリアーネ
コバレフスキ，ダニエル
ステヴァノヴィッチ，シュテファン
ヴァルツ，シモン
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イマティクス バイオテクノロジーズ ゲーエムベーハー
イマティクス バイオテクノロジーズ ゲーエムベーハー
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K40/00—Cellular immunotherapy
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12N5/0602—Vertebrate cells
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2310/00—Structure or type of the nucleic acid
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JP2017560907A 2015-06-25 2016-06-21 骨髄腫およびその他のがんの免疫療法において使用するための新規細胞エピトープおよび細胞エピトープ組み合わせ Pending JP2018520653A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562184500P 2015-06-25 2015-06-25
GBGB1511191.7A GB201511191D0 (en) 2015-06-25 2015-06-25 T-cell epitopes for the immunotherapy of myeloma
GB1511191.7 2015-06-25
US62/184,500 2015-06-25
PCT/EP2016/064317 WO2016207164A2 (en) 2015-06-25 2016-06-21 Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers

Publications (2)

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JP2018520653A true JP2018520653A (ja) 2018-08-02
JP2018520653A5 JP2018520653A5 (cg-RX-API-DMAC7.html) 2019-06-27

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US (2) US10196422B2 (cg-RX-API-DMAC7.html)
EP (1) EP3313860A2 (cg-RX-API-DMAC7.html)
JP (1) JP2018520653A (cg-RX-API-DMAC7.html)
KR (1) KR20180012865A (cg-RX-API-DMAC7.html)
CN (1) CN107889489A (cg-RX-API-DMAC7.html)
AU (1) AU2016284857A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017027639A2 (cg-RX-API-DMAC7.html)
CA (1) CA2990507A1 (cg-RX-API-DMAC7.html)
CR (1) CR20180051A (cg-RX-API-DMAC7.html)
EA (1) EA201792484A1 (cg-RX-API-DMAC7.html)
GB (1) GB201511191D0 (cg-RX-API-DMAC7.html)
IL (1) IL255932A (cg-RX-API-DMAC7.html)
MA (5) MA46506A1 (cg-RX-API-DMAC7.html)
MX (1) MX2017016207A (cg-RX-API-DMAC7.html)
PE (1) PE20180174A1 (cg-RX-API-DMAC7.html)
SG (1) SG10202001488VA (cg-RX-API-DMAC7.html)
TW (1) TW201710289A (cg-RX-API-DMAC7.html)
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JP2023519304A (ja) * 2020-03-27 2023-05-10 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 多発性骨髄腫における免疫療法の標的およびその同定方法

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