JP2018518465A5 - - Google Patents

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Publication number
JP2018518465A5
JP2018518465A5 JP2017557068A JP2017557068A JP2018518465A5 JP 2018518465 A5 JP2018518465 A5 JP 2018518465A5 JP 2017557068 A JP2017557068 A JP 2017557068A JP 2017557068 A JP2017557068 A JP 2017557068A JP 2018518465 A5 JP2018518465 A5 JP 2018518465A5
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JP
Japan
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seq
pharmaceutical composition
cells
composition according
tumor
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JP2017557068A
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English (en)
Japanese (ja)
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JP6956639B2 (ja
JP2018518465A (ja
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Priority claimed from PCT/US2016/026232 external-priority patent/WO2016178779A1/en
Publication of JP2018518465A publication Critical patent/JP2018518465A/ja
Publication of JP2018518465A5 publication Critical patent/JP2018518465A5/ja
Priority to JP2021099845A priority Critical patent/JP7203904B2/ja
Application granted granted Critical
Publication of JP6956639B2 publication Critical patent/JP6956639B2/ja
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JP2017557068A 2015-05-01 2016-04-06 抗ccr4抗体を用いてサイトカイン発現を媒介する方法 Active JP6956639B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021099845A JP7203904B2 (ja) 2015-05-01 2021-06-16 抗ccr4抗体を用いてサイトカイン発現を媒介する方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562155966P 2015-05-01 2015-05-01
US62/155,966 2015-05-01
US201562217419P 2015-09-11 2015-09-11
US62/217,419 2015-09-11
US201562237942P 2015-10-06 2015-10-06
US62/237,942 2015-10-06
PCT/US2016/026232 WO2016178779A1 (en) 2015-05-01 2016-04-06 Methods of mediating cytokine expression with anti ccr4 antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021099845A Division JP7203904B2 (ja) 2015-05-01 2021-06-16 抗ccr4抗体を用いてサイトカイン発現を媒介する方法

Publications (3)

Publication Number Publication Date
JP2018518465A JP2018518465A (ja) 2018-07-12
JP2018518465A5 true JP2018518465A5 (enExample) 2020-11-12
JP6956639B2 JP6956639B2 (ja) 2021-11-02

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ID=55795197

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017557068A Active JP6956639B2 (ja) 2015-05-01 2016-04-06 抗ccr4抗体を用いてサイトカイン発現を媒介する方法
JP2021099845A Active JP7203904B2 (ja) 2015-05-01 2021-06-16 抗ccr4抗体を用いてサイトカイン発現を媒介する方法

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JP2021099845A Active JP7203904B2 (ja) 2015-05-01 2021-06-16 抗ccr4抗体を用いてサイトカイン発現を媒介する方法

Country Status (8)

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US (2) US10556956B2 (enExample)
EP (1) EP3288977B1 (enExample)
JP (2) JP6956639B2 (enExample)
KR (1) KR20170138556A (enExample)
CN (1) CN107849134B (enExample)
AU (1) AU2016258742B9 (enExample)
NZ (1) NZ736863A (enExample)
WO (1) WO2016178779A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101510065B1 (ko) * 2005-06-08 2015-04-07 다나-파버 캔서 인스티튜트 인크. 예정 세포사 1(pd-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
JP7461741B2 (ja) 2016-06-20 2024-04-04 カイマブ・リミテッド 抗pd-l1およびil-2サイトカイン
AU2019387566A1 (en) 2018-11-30 2021-06-17 Dana-Farber Cancer Institute, Inc. Chimeric antigen receptor factories and methods of use thereof
WO2020252472A2 (en) 2019-06-14 2020-12-17 Dana-Farber Cancer Institute, Inc. Antibodies against muc1 and methods of use thereof
EP4255929A2 (en) 2020-12-02 2023-10-11 Vib Vzw An ltbr agonist in combination therapy against cancer
WO2024141063A1 (zh) * 2022-12-30 2024-07-04 甘李药业股份有限公司 抗rsv病毒抗体、组合物、制剂及其应用
WO2025145207A1 (en) 2023-12-29 2025-07-03 Bristol-Myers Squibb Company Combination therapy of kras inhibitor and treg-depleting agent

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA152990A (en) 1913-09-02 1914-01-06 Percy W. Tooth Rule pocket
FR2413974A1 (fr) 1978-01-06 1979-08-03 David Bernard Sechoir pour feuilles imprimees par serigraphie
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
DE3788058T2 (de) 1986-08-28 1994-04-21 Teijin Ltd Zelltoxischer antikörperkomplex und verfahren zu seiner herstellung.
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
EP0479909B1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ES2284161T3 (es) 1990-01-12 2007-11-01 Amgen Fremont Inc. Generacion de anticuerpos xenogenicos.
ATE204902T1 (de) 1990-06-29 2001-09-15 Large Scale Biology Corp Melaninproduktion durch transformierte mikroorganismen
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1992020373A1 (en) 1991-05-14 1992-11-26 Repligen Corporation Heteroconjugate antibodies for treatment of hiv infection
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
DE69303494T2 (de) 1992-11-13 1997-01-16 Idec Pharma Corp Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
EP0745134A1 (en) 1994-02-22 1996-12-04 Danafarber Cancer Institute Nucleic acid delivery system, method of synthesis and uses thereof
EP0822830B1 (en) 1995-04-27 2008-04-02 Amgen Fremont Inc. Human anti-IL-8 antibodies, derived from immunized xenomice
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
US20020029391A1 (en) 1998-04-15 2002-03-07 Claude Geoffrey Davis Epitope-driven human antibody production and gene expression profiling
US8962806B2 (en) * 2007-12-28 2015-02-24 Dana-Farber Cancer Institute, Inc. Humanized monoclonal antibodies and methods of use
WO2013166500A1 (en) * 2012-05-04 2013-11-07 Dana-Farber Cancer Institute, Inc. Affinity matured anti-ccr4 humanized monoclonal antibodies and methods of use
US9111624B2 (en) 2013-03-22 2015-08-18 Katsuyuki Fujita Semiconductor memory device
AU2015328273B2 (en) 2014-10-06 2020-09-17 Dana-Farber Cancer Institute, Inc. Humanized CC chemokine receptor 4 (CCR4) antibodies and methods of use thereof

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