JP2018517778A5 - - Google Patents
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- JP2018517778A5 JP2018517778A5 JP2018517499A JP2018517499A JP2018517778A5 JP 2018517778 A5 JP2018517778 A5 JP 2018517778A5 JP 2018517499 A JP2018517499 A JP 2018517499A JP 2018517499 A JP2018517499 A JP 2018517499A JP 2018517778 A5 JP2018517778 A5 JP 2018517778A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- tumor
- virus
- particles
- oncolytic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562182383P | 2015-06-19 | 2015-06-19 | |
| US62/182,383 | 2015-06-19 | ||
| PCT/IB2016/000993 WO2017037523A1 (en) | 2015-06-19 | 2016-06-17 | Compositions and methods for viral embolization |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018517778A JP2018517778A (ja) | 2018-07-05 |
| JP2018517778A5 true JP2018517778A5 (OSRAM) | 2019-07-18 |
| JP6827467B2 JP6827467B2 (ja) | 2021-02-10 |
Family
ID=58186857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517499A Active JP6827467B2 (ja) | 2015-06-19 | 2016-06-17 | ウイルス塞栓術のための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10517910B2 (OSRAM) |
| EP (1) | EP3310383B1 (OSRAM) |
| JP (1) | JP6827467B2 (OSRAM) |
| KR (1) | KR102735275B1 (OSRAM) |
| CN (1) | CN108025056B (OSRAM) |
| AU (1) | AU2016313969B2 (OSRAM) |
| ES (1) | ES2795010T3 (OSRAM) |
| WO (1) | WO2017037523A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016144564A2 (en) | 2015-02-25 | 2016-09-15 | Memorial Sloan-Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| CN107847534B (zh) | 2015-04-17 | 2022-10-04 | 纪念斯隆凯特琳癌症中心 | Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用 |
| CN108025056B (zh) | 2015-06-19 | 2022-01-14 | 新罗杰股份有限公司 | 用于病毒栓塞的组合物和方法 |
| US10512662B2 (en) | 2016-02-25 | 2019-12-24 | Memorial Sloan Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy |
| US10736962B2 (en) | 2016-02-25 | 2020-08-11 | Memorial Sloan Kettering Cancer Center | Recombinant MVA or MVADELE3L expressing human FLT3L and use thereof as immuno-therapeutic agents against solid tumors |
| KR102190326B1 (ko) * | 2016-07-21 | 2020-12-11 | 코오롱생명과학 주식회사 | 재조합 백시니아 바이러스 및 이의 용도 |
| US11242509B2 (en) | 2017-05-12 | 2022-02-08 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
| CN109554353B (zh) * | 2017-09-26 | 2021-08-06 | 杭州康万达医药科技有限公司 | 分离的重组溶瘤痘病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途 |
| KR20190059421A (ko) * | 2017-11-23 | 2019-05-31 | 주식회사 바이오녹스 | 항암바이러스의 간동맥 투여를 이용한 간암 치료방법 |
| KR20210031485A (ko) | 2018-07-13 | 2021-03-19 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | Tnf를 발현하는 점액종 바이러스로 암을 치료하는 방법 |
| MX2021003013A (es) | 2018-09-15 | 2021-08-11 | Memorial Sloan Kettering Cancer Center | Poxvirus recombinantes para inmunoterapia contra cáncer. |
| WO2020153734A1 (ko) * | 2019-01-25 | 2020-07-30 | 바이로큐어 주식회사 | 다람쥐 섬유종 바이러스 및 리오바이러스를 포함하는 암 예방 또는 치료용 약학적 조성물 |
| CA3129883A1 (en) * | 2019-02-14 | 2020-08-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
| KR20220112241A (ko) * | 2019-09-02 | 2022-08-10 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | 점액종 바이러스를 이용하여 암을 치료하기 위한 새로운 종양용해성 바이러스 플랫폼 |
| DE102020101197A1 (de) * | 2020-01-20 | 2021-07-22 | Charité - Universitätsmedizin Berlin | Medizinprodukt zur Arzneimittelabgabe mit verstärkter Wirkung |
| CN116322740A (zh) | 2020-07-13 | 2023-06-23 | 特兰斯吉恩股份有限公司 | 免疫抑制的治疗 |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| CN116942888B (zh) * | 2023-09-11 | 2026-03-24 | 科睿驰（深圳）医疗科技发展有限公司 | 淀粉水凝胶栓塞微球及其制备方法 |
| WO2026041811A1 (en) | 2024-08-23 | 2026-02-26 | Transgene | Recombinant poxvirus and method for regulating the expression of toxic conditional gene products of said recombinant poxvirus in a producing cell |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| CA2133339A1 (en) | 1992-04-08 | 1993-10-09 | Jennifer S. Rota | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
| FR2736358B1 (fr) | 1995-07-05 | 1997-09-26 | Agronomique Inst Nat Rech | Virus myxomateux recombinant |
| WO1999012577A1 (en) | 1997-09-05 | 1999-03-18 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization |
| FR2784580B1 (fr) * | 1998-10-16 | 2004-06-25 | Biosepra Inc | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
| EP1267839B1 (en) * | 2000-03-24 | 2007-10-03 | Biosphere Medical, Inc. | Microspheres for active embolization |
| AU2001294458B2 (en) * | 2000-10-06 | 2004-03-11 | Jagotec Ag | Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight |
| WO2003094938A1 (en) | 2002-05-09 | 2003-11-20 | Oncolytics Biotech Inc. | Method for reducing pain using oncolytic viruses |
| EP2269619A1 (en) * | 2002-08-12 | 2011-01-05 | Jennerex Biotherapeutics ULC | Methods and compositions concerning poxviruses and cancer |
| US8980246B2 (en) * | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
| CN101351213B (zh) * | 2005-09-07 | 2013-10-02 | 詹纳里克斯公司 | 使用表达gm-csf的痘病毒系统性治疗转移性癌和/或全身散布性癌 |
| WO2008105504A1 (ja) * | 2007-03-01 | 2008-09-04 | Cosmed Pharmaceutical Co., Ltd. | 経皮免疫製剤、その製造方法及びそれを用いた経皮免疫方法 |
| KR20080084528A (ko) * | 2007-03-15 | 2008-09-19 | 제네렉스 바이오테라퓨틱스 인크. | 종양살상형 백시니아 바이러스 암 치료 |
| ES2671570T3 (es) * | 2009-09-14 | 2018-06-07 | Sillajen Biotherapeutics, Inc. | Terapia combinada contra el cáncer con virus oncolítico de vaccinia |
| WO2011135734A1 (ja) * | 2010-04-28 | 2011-11-03 | 株式会社アルファ・ナノ・メディカ | ウイルスの複合体、それを含有する治療薬及び治療方法 |
| US9724421B2 (en) * | 2010-11-29 | 2017-08-08 | Centre Hospitalier Universitaire Vaudois | Chemoembolization composition comprising anti-angiogenic agents |
| CN103429258B (zh) * | 2011-01-04 | 2016-03-09 | 新罗杰公司 | 通过施用溶瘤痘苗病毒生成针对肿瘤抗原的抗体和生成肿瘤特异性补体依赖性细胞毒性 |
| ES2813413T3 (es) * | 2011-08-05 | 2021-03-23 | Sillajen Biotherapeutics Inc | Métodos y composiciones para la producción de virus vaccina |
| WO2014031693A1 (en) * | 2012-08-20 | 2014-02-27 | Genelux Corporation | Compositions containing protein polymers and vaccinia virus, and methods of use thereof |
| US20140194370A1 (en) * | 2013-01-08 | 2014-07-10 | University Of Utah Research Foundation | Silk-elastin like protein polymers for embolization and chemoembolization to treat cancer |
| CN108025056B (zh) | 2015-06-19 | 2022-01-14 | 新罗杰股份有限公司 | 用于病毒栓塞的组合物和方法 |
| HK1255192A1 (zh) * | 2015-09-08 | 2019-08-09 | Sillajen, Inc. | 表达细胞因子和羧酸酯酶的修饰的溶瘤痘苗病毒及其使用方法 |
-
2016
- 2016-06-17 CN CN201680048316.5A patent/CN108025056B/zh active Active
- 2016-06-17 JP JP2018517499A patent/JP6827467B2/ja active Active
- 2016-06-17 ES ES16840890T patent/ES2795010T3/es active Active
- 2016-06-17 KR KR1020187001688A patent/KR102735275B1/ko active Active
- 2016-06-17 US US15/738,034 patent/US10517910B2/en active Active
- 2016-06-17 EP EP16840890.4A patent/EP3310383B1/en active Active
- 2016-06-17 WO PCT/IB2016/000993 patent/WO2017037523A1/en not_active Ceased
- 2016-06-17 AU AU2016313969A patent/AU2016313969B2/en not_active Ceased
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