JP2018517735A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018517735A5 JP2018517735A5 JP2017565133A JP2017565133A JP2018517735A5 JP 2018517735 A5 JP2018517735 A5 JP 2018517735A5 JP 2017565133 A JP2017565133 A JP 2017565133A JP 2017565133 A JP2017565133 A JP 2017565133A JP 2018517735 A5 JP2018517735 A5 JP 2018517735A5
- Authority
- JP
- Japan
- Prior art keywords
- dmf
- particles
- particle
- less
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- LDCRTTXIJACKKU-ONEGZZNKSA-N dimethyl fumarate Chemical compound COC(=O)\C=C\C(=O)OC LDCRTTXIJACKKU-ONEGZZNKSA-N 0.000 claims 32
- 229960004419 dimethyl fumarate Drugs 0.000 claims 32
- 239000002245 particle Substances 0.000 claims 27
- 239000002552 dosage form Substances 0.000 claims 7
- 239000012528 membrane Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 210000002784 stomach Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 230000035699 permeability Effects 0.000 claims 2
- 210000000813 small intestine Anatomy 0.000 claims 2
- 102000057297 Pepsin A Human genes 0.000 claims 1
- 108090000284 Pepsin A Proteins 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 230000001186 cumulative effect Effects 0.000 claims 1
- 239000012738 dissolution medium Substances 0.000 claims 1
- 238000007922 dissolution test Methods 0.000 claims 1
- 239000002702 enteric coating Substances 0.000 claims 1
- 238000009505 enteric coating Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000004051 gastric juice Anatomy 0.000 claims 1
- 230000000887 hydrating effect Effects 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 229940111202 pepsin Drugs 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 238000001238 wet grinding Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021184469A JP2022042512A (ja) | 2015-06-17 | 2021-11-12 | フマル酸ジメチル粒子及びそれらの医薬組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562181061P | 2015-06-17 | 2015-06-17 | |
| US62/181,061 | 2015-06-17 | ||
| PCT/US2016/037486 WO2016205270A1 (en) | 2015-06-17 | 2016-06-15 | Dimethyl fumarate particles and pharmaceutical compositions thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021184469A Division JP2022042512A (ja) | 2015-06-17 | 2021-11-12 | フマル酸ジメチル粒子及びそれらの医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018517735A JP2018517735A (ja) | 2018-07-05 |
| JP2018517735A5 true JP2018517735A5 (cg-RX-API-DMAC7.html) | 2019-07-18 |
Family
ID=56292916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017565133A Pending JP2018517735A (ja) | 2015-06-17 | 2016-06-15 | フマル酸ジメチル粒子及びそれらの医薬組成物 |
| JP2021184469A Pending JP2022042512A (ja) | 2015-06-17 | 2021-11-12 | フマル酸ジメチル粒子及びそれらの医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021184469A Pending JP2022042512A (ja) | 2015-06-17 | 2021-11-12 | フマル酸ジメチル粒子及びそれらの医薬組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11291642B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3310341A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2018517735A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180018711A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107920997A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2016279997B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2989581A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201890068A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1254054A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL256296A (cg-RX-API-DMAC7.html) |
| MA (1) | MA42196A (cg-RX-API-DMAC7.html) |
| MX (1) | MX387092B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016205270A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018005345A (es) * | 2015-10-28 | 2018-08-14 | Sun Pharmaceutical Ind Ltd | Composiciones farmaceuticas de dimetil fumarato. |
| JP6902043B2 (ja) * | 2016-02-11 | 2021-07-14 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | フマル酸ジメチルを含む医薬ビーズ製剤 |
| KR102613659B1 (ko) * | 2017-10-02 | 2023-12-15 | 노파르티스 아게 | 제약 제품의 제조 방법 |
| US11318682B2 (en) | 2018-04-06 | 2022-05-03 | Hewlett-Packard Development Company, L.P. | Three-dimensional (3D) object printing based on build material permeability |
| US12098291B2 (en) * | 2018-10-05 | 2024-09-24 | Isp Investments Llc | Smooth high solids film coating composition comprising water soluble cellulose ether, process for preparing the same and method of use thereof |
| TR201818293A2 (tr) * | 2018-11-30 | 2020-06-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Di̇meti̇l fumarat i̇çeren geci̇kmeli̇ salim sağlayan kapsül |
| AU2020214626B2 (en) * | 2019-01-31 | 2025-10-16 | Elektrofi, Inc. | Particle formation and morphology |
| EP3941444B1 (en) * | 2019-03-20 | 2025-03-26 | Lyndra Therapeutics, Inc. | Coatings for gastric residence dosage forms |
| CN113966216A (zh) * | 2019-03-20 | 2022-01-21 | 林德拉治疗公司 | 用于胃滞留剂型的胶囊和胶囊衣层 |
| CN116669715A (zh) * | 2020-11-18 | 2023-08-29 | Fb-Hrs有限责任公司 | 含有多非利特和美西律的组合物及其应用 |
| AU2021391823A1 (en) | 2020-12-03 | 2023-06-29 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| IL307454A (en) | 2021-04-07 | 2023-12-01 | Battelle Memorial Institute | Technologies for rapid design, construction, testing, learning to identify and use non-viral vectors |
| MX2023014395A (es) | 2021-06-04 | 2023-12-15 | Zim Laboratories Ltd | Composiciones de liberacion retardada de dimetilfumarato. |
| US11590071B2 (en) * | 2021-07-06 | 2023-02-28 | King Abdulaziz University | Injectable drug delivery implant composition and method of use thereof |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025090498A1 (en) * | 2023-10-23 | 2025-05-01 | Isp Investments Llc | Encapsulated medium chain fatty acid salts and oral solid dosage forms derived therefrom |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2725623A1 (fr) | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
| US5972389A (en) | 1996-09-19 | 1999-10-26 | Depomed, Inc. | Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter |
| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| IL133196A0 (en) | 1999-11-29 | 2001-03-19 | Yissum Res Dev Co | Gastroretentive controlled release pharmaceutical dosage forms |
| DE10101307A1 (de) | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
| US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
| PL2801354T3 (pl) * | 2004-10-08 | 2017-08-31 | Forward Pharma A/S | Kompozycje farmaceutyczne o kontrolowanym uwalnianiu zawierające ester kwasu fumarowego |
| CA2637655C (en) | 2006-01-18 | 2017-06-27 | Intec Pharma Ltd. | Method and apparatus for forming delivery devices for oral intake of an agent |
| DK2276473T3 (en) * | 2008-04-18 | 2017-01-09 | Intec Pharma Ltd | GASTRORETENTIV drug TO carbidopa / levodopa |
| US20120034274A1 (en) * | 2009-01-09 | 2012-02-09 | Forward Pharma A/S | Pharmaceutical composition comprising one or more fumaric acid esters |
| RU2743637C2 (ru) * | 2009-01-09 | 2021-02-20 | Фвп Ип Апс | Фармацевтический состав, содержащий один или более эфиров фумаровой кислоты в разлагаемой матрице |
| PH12013502498A1 (en) * | 2011-06-08 | 2014-01-20 | Biogen Ma Inc | Process for preparing high purity and crystalline dimethyl fumarate |
| RU2014125430A (ru) * | 2011-11-24 | 2015-12-27 | Синтон Бв | Контролируемое высвобождение частиц, содержащих диметилфумарат |
| PE20150092A1 (es) | 2012-02-07 | 2015-02-06 | Biogen Idec Inc | Composiciones farmaceuticas que contienen fumarato de dimetilo |
| WO2015042294A1 (en) | 2013-09-18 | 2015-03-26 | Xenoport, Inc. | Nanoparticle compositions of dimethyl fumarate |
| WO2015044853A2 (en) | 2013-09-25 | 2015-04-02 | Glenmark Pharmaceuticals Limited; Glenmark Generics Limited | Process for preparation of dimethyl fumarate |
| EP3079663A1 (en) * | 2013-12-13 | 2016-10-19 | Biogen MA Inc. | Controlled release dosage form for once daily administration of dimethyl fumarate |
| EP3501510B1 (en) * | 2014-02-28 | 2020-07-01 | Banner Life Sciences LLC | Controlled release enteric soft capsules of fumarate esters |
-
2016
- 2016-06-15 EA EA201890068A patent/EA201890068A1/ru unknown
- 2016-06-15 WO PCT/US2016/037486 patent/WO2016205270A1/en not_active Ceased
- 2016-06-15 CA CA2989581A patent/CA2989581A1/en active Pending
- 2016-06-15 MA MA042196A patent/MA42196A/fr unknown
- 2016-06-15 HK HK18113117.1A patent/HK1254054A1/zh unknown
- 2016-06-15 EP EP16733793.0A patent/EP3310341A1/en not_active Withdrawn
- 2016-06-15 US US15/737,011 patent/US11291642B2/en active Active
- 2016-06-15 KR KR1020187001091A patent/KR20180018711A/ko not_active Ceased
- 2016-06-15 JP JP2017565133A patent/JP2018517735A/ja active Pending
- 2016-06-15 MX MX2017016509A patent/MX387092B/es unknown
- 2016-06-15 AU AU2016279997A patent/AU2016279997B2/en not_active Ceased
- 2016-06-15 CN CN201680047251.2A patent/CN107920997A/zh active Pending
-
2017
- 2017-12-13 IL IL256296A patent/IL256296A/en unknown
-
2021
- 2021-11-12 JP JP2021184469A patent/JP2022042512A/ja active Pending
-
2022
- 2022-01-12 AU AU2022200155A patent/AU2022200155A1/en not_active Abandoned
- 2022-02-22 US US17/677,204 patent/US20220362195A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018517735A5 (cg-RX-API-DMAC7.html) | ||
| JP6105761B2 (ja) | 腸溶性被覆されたマルチ粒子徐放性ペパーミントオイル組成物及び関連方法 | |
| ES2688889T3 (es) | Proceso de mezcla sin disolvente para el recubrimiento de ingredientes farmacéuticos | |
| KR20190107712A (ko) | 특정 위장 부위에서의 제어 방출의 투여 형태 | |
| JP2014528431A5 (cg-RX-API-DMAC7.html) | ||
| KR20180018711A (ko) | 디메틸 푸마레이트 입자 및 이들의 약제학적 조성물 | |
| JP2016514686A5 (cg-RX-API-DMAC7.html) | ||
| RU2015110825A (ru) | Устойчивая к действию желудочного сока фармацевтическая или нутрицевтическая композиция со стойкостью к влиянию этанола | |
| JP2009525300A5 (cg-RX-API-DMAC7.html) | ||
| JP2016516698A5 (cg-RX-API-DMAC7.html) | ||
| JP2016513724A5 (cg-RX-API-DMAC7.html) | ||
| WO2015193788A1 (en) | Formulation for oral administration containing mesalazine | |
| JP2011509264A (ja) | 結腸内での活性物質放出が強化された、コーティングされた医薬製剤もしくはニュートラシューティカル製剤 | |
| JP2015533162A5 (cg-RX-API-DMAC7.html) | ||
| CN110035744A (zh) | 一种尼拉帕尼缓控释药物组合物及其用途 | |
| EA031255B1 (ru) | Состав с отсроченным высвобождением, содержащий гранулы цистеамина, и способы его получения и применения | |
| CN103228676A (zh) | 羟烷基纤维素 | |
| JP2018516266A5 (cg-RX-API-DMAC7.html) | ||
| CN111372568B (zh) | 水溶性聚合物粘合层 | |
| HRP20231012T1 (hr) | Novi sastav s odgođenim oslobađenjem za peroralno davanje | |
| RU2009137911A (ru) | Порошки для создания жирной лекарственной формы | |
| CN101862305B (zh) | 一种盐酸氨溴索缓释微丸及制备方法 | |
| Kadian et al. | Eudragit and its pharmaceutical significance | |
| JP6255416B2 (ja) | 積層フィルム及びフィルム積層方法 | |
| Shavi et al. | Multiparticulate drug delivery system of aceclofenac: development and in vitro studies |