CA2989581A1 - Dimethyl fumarate particles and pharmaceutical compositions thereof - Google Patents
Dimethyl fumarate particles and pharmaceutical compositions thereof Download PDFInfo
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- CA2989581A1 CA2989581A1 CA2989581A CA2989581A CA2989581A1 CA 2989581 A1 CA2989581 A1 CA 2989581A1 CA 2989581 A CA2989581 A CA 2989581A CA 2989581 A CA2989581 A CA 2989581A CA 2989581 A1 CA2989581 A1 CA 2989581A1
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- LDCRTTXIJACKKU-ONEGZZNKSA-N dimethyl fumarate Chemical compound COC(=O)\C=C\C(=O)OC LDCRTTXIJACKKU-ONEGZZNKSA-N 0.000 title claims abstract description 568
- 229960004419 dimethyl fumarate Drugs 0.000 title claims abstract description 567
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 36
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| MX2018005345A (es) * | 2015-10-28 | 2018-08-14 | Sun Pharmaceutical Ind Ltd | Composiciones farmaceuticas de dimetil fumarato. |
| JP6902043B2 (ja) * | 2016-02-11 | 2021-07-14 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | フマル酸ジメチルを含む医薬ビーズ製剤 |
| KR102613659B1 (ko) * | 2017-10-02 | 2023-12-15 | 노파르티스 아게 | 제약 제품의 제조 방법 |
| US11318682B2 (en) | 2018-04-06 | 2022-05-03 | Hewlett-Packard Development Company, L.P. | Three-dimensional (3D) object printing based on build material permeability |
| US12098291B2 (en) * | 2018-10-05 | 2024-09-24 | Isp Investments Llc | Smooth high solids film coating composition comprising water soluble cellulose ether, process for preparing the same and method of use thereof |
| TR201818293A2 (tr) * | 2018-11-30 | 2020-06-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Di̇meti̇l fumarat i̇çeren geci̇kmeli̇ salim sağlayan kapsül |
| AU2020214626B2 (en) * | 2019-01-31 | 2025-10-16 | Elektrofi, Inc. | Particle formation and morphology |
| EP3941444B1 (en) * | 2019-03-20 | 2025-03-26 | Lyndra Therapeutics, Inc. | Coatings for gastric residence dosage forms |
| CN113966216A (zh) * | 2019-03-20 | 2022-01-21 | 林德拉治疗公司 | 用于胃滞留剂型的胶囊和胶囊衣层 |
| CN116669715A (zh) * | 2020-11-18 | 2023-08-29 | Fb-Hrs有限责任公司 | 含有多非利特和美西律的组合物及其应用 |
| AU2021391823A1 (en) | 2020-12-03 | 2023-06-29 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| IL307454A (en) | 2021-04-07 | 2023-12-01 | Battelle Memorial Institute | Technologies for rapid design, construction, testing, learning to identify and use non-viral vectors |
| MX2023014395A (es) | 2021-06-04 | 2023-12-15 | Zim Laboratories Ltd | Composiciones de liberacion retardada de dimetilfumarato. |
| US11590071B2 (en) * | 2021-07-06 | 2023-02-28 | King Abdulaziz University | Injectable drug delivery implant composition and method of use thereof |
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| FR2725623A1 (fr) | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
| US5972389A (en) | 1996-09-19 | 1999-10-26 | Depomed, Inc. | Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter |
| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| IL133196A0 (en) | 1999-11-29 | 2001-03-19 | Yissum Res Dev Co | Gastroretentive controlled release pharmaceutical dosage forms |
| DE10101307A1 (de) | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
| US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
| PL2801354T3 (pl) * | 2004-10-08 | 2017-08-31 | Forward Pharma A/S | Kompozycje farmaceutyczne o kontrolowanym uwalnianiu zawierające ester kwasu fumarowego |
| CA2637655C (en) | 2006-01-18 | 2017-06-27 | Intec Pharma Ltd. | Method and apparatus for forming delivery devices for oral intake of an agent |
| DK2276473T3 (en) * | 2008-04-18 | 2017-01-09 | Intec Pharma Ltd | GASTRORETENTIV drug TO carbidopa / levodopa |
| US20120034274A1 (en) * | 2009-01-09 | 2012-02-09 | Forward Pharma A/S | Pharmaceutical composition comprising one or more fumaric acid esters |
| RU2743637C2 (ru) * | 2009-01-09 | 2021-02-20 | Фвп Ип Апс | Фармацевтический состав, содержащий один или более эфиров фумаровой кислоты в разлагаемой матрице |
| PH12013502498A1 (en) * | 2011-06-08 | 2014-01-20 | Biogen Ma Inc | Process for preparing high purity and crystalline dimethyl fumarate |
| RU2014125430A (ru) * | 2011-11-24 | 2015-12-27 | Синтон Бв | Контролируемое высвобождение частиц, содержащих диметилфумарат |
| PE20150092A1 (es) | 2012-02-07 | 2015-02-06 | Biogen Idec Inc | Composiciones farmaceuticas que contienen fumarato de dimetilo |
| WO2015042294A1 (en) | 2013-09-18 | 2015-03-26 | Xenoport, Inc. | Nanoparticle compositions of dimethyl fumarate |
| WO2015044853A2 (en) | 2013-09-25 | 2015-04-02 | Glenmark Pharmaceuticals Limited; Glenmark Generics Limited | Process for preparation of dimethyl fumarate |
| EP3079663A1 (en) * | 2013-12-13 | 2016-10-19 | Biogen MA Inc. | Controlled release dosage form for once daily administration of dimethyl fumarate |
| EP3501510B1 (en) * | 2014-02-28 | 2020-07-01 | Banner Life Sciences LLC | Controlled release enteric soft capsules of fumarate esters |
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| CN107920997A (zh) | 2018-04-17 |
| WO2016205270A1 (en) | 2016-12-22 |
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| EP3310341A1 (en) | 2018-04-25 |
| WO2016205270A8 (en) | 2017-01-19 |
| US11291642B2 (en) | 2022-04-05 |
| IL256296A (en) | 2018-02-28 |
| JP2022042512A (ja) | 2022-03-14 |
| EA201890068A1 (ru) | 2018-09-28 |
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