MX2018005345A - Composiciones farmaceuticas de dimetil fumarato. - Google Patents
Composiciones farmaceuticas de dimetil fumarato.Info
- Publication number
- MX2018005345A MX2018005345A MX2018005345A MX2018005345A MX2018005345A MX 2018005345 A MX2018005345 A MX 2018005345A MX 2018005345 A MX2018005345 A MX 2018005345A MX 2018005345 A MX2018005345 A MX 2018005345A MX 2018005345 A MX2018005345 A MX 2018005345A
- Authority
- MX
- Mexico
- Prior art keywords
- dimethyl fumarate
- present
- pharmaceutical compositions
- compositions
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona a una composición farmacéutica que comprende dimetil fumarato; un modulador de enzima o un aumentador de permeación o ambos; y uno o etas excipientes farmacéuticamente aceptables. Además se relaciona a una composición farmacéutica de liberación pulsátil que comprende dimetil fumarato y uno o más excipientes farmacéuticamente aceptables. Las composiciones de la presente invención se administran a una dosis más baja como se compara con la dosis diaria recomendada de Tecfidera(r). Además, las composiciones de la presente invención son resistentes a descarga de dosis en la presencia de alcohol.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3504DE2015 | 2015-10-28 | ||
PCT/IB2016/056479 WO2017072699A1 (en) | 2015-10-28 | 2016-10-27 | Pharmaceutical compositions of dimethyl fumarate |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018005345A true MX2018005345A (es) | 2018-08-14 |
Family
ID=58631325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018005345A MX2018005345A (es) | 2015-10-28 | 2016-10-27 | Composiciones farmaceuticas de dimetil fumarato. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20180318246A1 (es) |
EP (1) | EP3368030A4 (es) |
AU (1) | AU2016344673A1 (es) |
BR (1) | BR112018008835A8 (es) |
CA (1) | CA3003237A1 (es) |
MA (1) | MA43126A (es) |
MX (1) | MX2018005345A (es) |
RU (1) | RU2018118603A (es) |
WO (1) | WO2017072699A1 (es) |
ZA (1) | ZA201803032B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3302461A4 (en) * | 2015-06-01 | 2019-02-13 | Sun Pharmaceutical Industries Ltd | PHARMACEUTICAL COMPOSITIONS OF DIMETHYLFUMARATE |
WO2020053218A1 (en) * | 2018-09-13 | 2020-03-19 | Almirall, S.A. | Treatment of psoriasis |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19853487A1 (de) * | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
CN102697704A (zh) * | 2003-09-26 | 2012-10-03 | 阿尔扎公司 | 阿片类与非阿片类镇痛药的控释制剂 |
WO2011039768A2 (en) * | 2009-09-17 | 2011-04-07 | Cadila Healthcare Limited | Pharmaceutical compositions for reducing alcohol-induced dose dumping |
US20130158077A1 (en) * | 2011-12-19 | 2013-06-20 | Ares Trading S.A. | Pharmaceutical compositions |
EP2811994A4 (en) * | 2012-02-07 | 2016-01-13 | Biogen Ma Inc | PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE |
SG11201509738RA (en) * | 2013-05-31 | 2015-12-30 | Takeda Pharmaceuticals Usa Inc | Methods of treatment and compositions with xanthine oxidase inhibitors |
US20150079180A1 (en) * | 2013-09-18 | 2015-03-19 | Xenoport, Inc. | Nanoparticle compositions of dimethyl fumarate |
WO2015105757A1 (en) * | 2014-01-07 | 2015-07-16 | Biogen Ma Inc. | Dimethyl fumarate for treating multiple sclerosis |
MX2017016509A (es) * | 2015-06-17 | 2018-08-16 | Biogen Ma Inc | Particulas de dimetilfumarato y composiciones farmaceuticas de estas. |
-
2016
- 2016-10-27 MX MX2018005345A patent/MX2018005345A/es unknown
- 2016-10-27 WO PCT/IB2016/056479 patent/WO2017072699A1/en active Application Filing
- 2016-10-27 AU AU2016344673A patent/AU2016344673A1/en not_active Abandoned
- 2016-10-27 MA MA043126A patent/MA43126A/fr unknown
- 2016-10-27 RU RU2018118603A patent/RU2018118603A/ru not_active Application Discontinuation
- 2016-10-27 US US15/772,455 patent/US20180318246A1/en not_active Abandoned
- 2016-10-27 CA CA3003237A patent/CA3003237A1/en not_active Abandoned
- 2016-10-27 BR BR112018008835A patent/BR112018008835A8/pt not_active Application Discontinuation
- 2016-10-27 EP EP16859177.4A patent/EP3368030A4/en not_active Withdrawn
-
2018
- 2018-05-09 ZA ZA2018/03032A patent/ZA201803032B/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA43126A (fr) | 2018-09-05 |
WO2017072699A1 (en) | 2017-05-04 |
RU2018118603A (ru) | 2019-11-28 |
AU2016344673A1 (en) | 2018-05-17 |
EP3368030A4 (en) | 2019-05-01 |
US20180318246A1 (en) | 2018-11-08 |
ZA201803032B (en) | 2019-07-31 |
EP3368030A1 (en) | 2018-09-05 |
CA3003237A1 (en) | 2017-05-04 |
BR112018008835A8 (pt) | 2019-02-26 |
BR112018008835A2 (pt) | 2018-11-06 |
RU2018118603A3 (es) | 2020-03-06 |
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