JP2018516566A5 - - Google Patents
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- JP2018516566A5 JP2018516566A5 JP2017560327A JP2017560327A JP2018516566A5 JP 2018516566 A5 JP2018516566 A5 JP 2018516566A5 JP 2017560327 A JP2017560327 A JP 2017560327A JP 2017560327 A JP2017560327 A JP 2017560327A JP 2018516566 A5 JP2018516566 A5 JP 2018516566A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- enpp1
- pharmaceutical composition
- residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021202984A JP7390349B2 (ja) | 2015-05-19 | 2021-12-15 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2023196352A JP7778392B2 (ja) | 2015-05-19 | 2023-11-20 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2025191616A JP2026015456A (ja) | 2015-05-19 | 2025-11-12 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163500P | 2015-05-19 | 2015-05-19 | |
| US62/163,500 | 2015-05-19 | ||
| PCT/US2016/033236 WO2016187408A1 (en) | 2015-05-19 | 2016-05-19 | Compositions for treating pathological calcification conditions, and methods using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021202984A Division JP7390349B2 (ja) | 2015-05-19 | 2021-12-15 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018516566A JP2018516566A (ja) | 2018-06-28 |
| JP2018516566A5 true JP2018516566A5 (https=) | 2019-06-20 |
| JP6995627B2 JP6995627B2 (ja) | 2022-02-04 |
Family
ID=57320640
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560327A Active JP6995627B2 (ja) | 2015-05-19 | 2016-05-19 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2021202984A Active JP7390349B2 (ja) | 2015-05-19 | 2021-12-15 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2023196352A Active JP7778392B2 (ja) | 2015-05-19 | 2023-11-20 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2025191616A Pending JP2026015456A (ja) | 2015-05-19 | 2025-11-12 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021202984A Active JP7390349B2 (ja) | 2015-05-19 | 2021-12-15 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2023196352A Active JP7778392B2 (ja) | 2015-05-19 | 2023-11-20 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
| JP2025191616A Pending JP2026015456A (ja) | 2015-05-19 | 2025-11-12 | 病的石灰化状態を治療するための組成物およびそれを使用する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (10) | US10583170B2 (https=) |
| EP (2) | EP4414028A3 (https=) |
| JP (4) | JP6995627B2 (https=) |
| KR (2) | KR102811896B1 (https=) |
| AU (3) | AU2016264364B2 (https=) |
| CA (2) | CA3176123A1 (https=) |
| ES (1) | ES2983910T3 (https=) |
| MX (2) | MX391074B (https=) |
| PL (1) | PL3298140T3 (https=) |
| RU (2) | RU2021129201A (https=) |
| WO (1) | WO2016187408A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011207563B2 (en) | 2010-01-19 | 2016-03-10 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
| WO2014126965A2 (en) | 2013-02-13 | 2014-08-21 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| TR201908550T4 (tr) | 2014-06-04 | 2019-07-22 | Exicure Inc | Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi. |
| EP3967755B1 (en) * | 2014-12-19 | 2024-03-27 | Inozyme Pharma, Inc. | Soluble npp1 for use in a method for treating pseudoxanthoma elasticum |
| EP4414028A3 (en) | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
| EP3377105A4 (en) | 2015-11-20 | 2019-04-24 | Yale University | COMPOSITIONS FOR THE TREATMENT OF ECTOPIC CALIBRATION DISORDERS AND METHODS THEREWITH |
| EP3471747A1 (en) | 2016-06-16 | 2019-04-24 | Alexion Pharmaceuticals, Inc. | Methods of treating myointimal proliferation |
| CA3032467A1 (en) | 2016-08-05 | 2018-02-08 | Yale University | Compositions and methods for stroke prevention in pediatric sickle cell anemia patients |
| US11696954B2 (en) | 2017-04-28 | 2023-07-11 | Exicure Operating Company | Synthesis of spherical nucleic acids using lipophilic moieties |
| US12134790B2 (en) | 2017-09-27 | 2024-11-05 | Inozyme Pharma, Inc. | Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (NPP1) |
| AU2019267545A1 (en) | 2018-05-08 | 2020-11-26 | Yale University | Compositions and methods for reducing progression of nephrolithiasis |
| CN120383683A (zh) * | 2018-08-31 | 2025-07-29 | 耶鲁大学 | Enpp1多肽及其使用方法 |
| CA3126839A1 (en) * | 2019-01-18 | 2020-07-23 | Inozyme Pharma, Inc. | Treatment of diseases involving deficiency of enpp1 or enpp3 |
| US12502354B2 (en) | 2019-01-24 | 2025-12-23 | Northwestern University | High density lipoprotein mimetic nanoparticles using lipid conjugated core scaffolds |
| CA3136118A1 (en) * | 2019-04-05 | 2020-10-08 | Yale University | Enpp1 polypeptides and methods of using same |
| KR20230048480A (ko) * | 2020-05-27 | 2023-04-11 | 이노자임 파마, 인코포레이티드 | 말초 동맥 질환을 치료하기 위한 조성물 및 방법 |
| WO2021252549A1 (en) | 2020-06-09 | 2021-12-16 | Inozyme Pharma, Inc. | Soluble enpp1 or enpp3 proteins and uses thereof |
| CA3195071A1 (en) * | 2020-10-08 | 2022-04-14 | Inozyme Pharma, Inc. | Liver specific production of enpp1 or enpp3 |
| MX2023005836A (es) * | 2020-11-19 | 2023-08-17 | Inozyme Pharma Inc | Tratamiento para la deficiencia de enpp1 y la deficiencia de abcc6. |
| CA3231858A1 (en) * | 2021-09-24 | 2023-03-30 | Inozyme Pharma, Inc. | Lyophilized enpp1 polypeptide formulations and uses thereof |
| WO2025042995A1 (en) * | 2023-08-22 | 2025-02-27 | Inozyme Pharma, Inc. | Treatment of enpp1 deficiency and abcc6 deficiency in children |
| WO2025255052A1 (en) * | 2024-06-03 | 2025-12-11 | Inozyme Pharma, Inc. | Treatment of enpp1 deficiency and abcc6 deficiency in infants |
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| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
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| RU2601154C2 (ru) * | 2011-03-11 | 2016-10-27 | Синаджива Байофарма Корп | Гибридные белки npp1 |
| WO2014126965A2 (en) | 2013-02-13 | 2014-08-21 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| ES2708565T3 (es) | 2013-03-15 | 2019-04-10 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
| EP3967755B1 (en) | 2014-12-19 | 2024-03-27 | Inozyme Pharma, Inc. | Soluble npp1 for use in a method for treating pseudoxanthoma elasticum |
| EP4414028A3 (en) * | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
-
2016
- 2016-05-19 EP EP24171629.9A patent/EP4414028A3/en active Pending
- 2016-05-19 PL PL16797290.0T patent/PL3298140T3/pl unknown
- 2016-05-19 ES ES16797290T patent/ES2983910T3/es active Active
- 2016-05-19 RU RU2021129201A patent/RU2021129201A/ru unknown
- 2016-05-19 JP JP2017560327A patent/JP6995627B2/ja active Active
- 2016-05-19 CA CA3176123A patent/CA3176123A1/en active Pending
- 2016-05-19 EP EP16797290.0A patent/EP3298140B1/en active Active
- 2016-05-19 MX MX2017014805A patent/MX391074B/es unknown
- 2016-05-19 WO PCT/US2016/033236 patent/WO2016187408A1/en not_active Ceased
- 2016-05-19 KR KR1020177036279A patent/KR102811896B1/ko active Active
- 2016-05-19 RU RU2017144183A patent/RU2757417C2/ru active
- 2016-05-19 CA CA2984947A patent/CA2984947A1/en active Pending
- 2016-05-19 KR KR1020257016455A patent/KR20250078598A/ko active Pending
- 2016-05-19 AU AU2016264364A patent/AU2016264364B2/en active Active
-
2017
- 2017-08-09 US US15/672,899 patent/US10583170B2/en active Active
- 2017-08-09 US US15/672,791 patent/US10064917B2/en active Active
- 2017-11-14 US US15/812,553 patent/US10357541B2/en active Active
- 2017-11-14 US US15/812,342 patent/US10213484B2/en active Active
- 2017-11-14 US US15/812,456 patent/US10960049B2/en active Active
- 2017-11-17 MX MX2022003467A patent/MX2022003467A/es unknown
-
2019
- 2019-04-10 US US16/380,557 patent/US10517927B2/en active Active
- 2019-12-27 US US16/728,129 patent/US11090359B2/en active Active
-
2020
- 2020-03-25 US US16/829,966 patent/US10960050B2/en active Active
-
2021
- 2021-07-07 US US17/369,830 patent/US12128087B2/en active Active
- 2021-12-15 JP JP2021202984A patent/JP7390349B2/ja active Active
-
2022
- 2022-09-23 AU AU2022235636A patent/AU2022235636B2/en active Active
-
2023
- 2023-11-20 JP JP2023196352A patent/JP7778392B2/ja active Active
-
2024
- 2024-10-16 US US18/916,911 patent/US20250295733A1/en active Pending
-
2025
- 2025-08-14 AU AU2025217333A patent/AU2025217333A1/en active Pending
- 2025-11-12 JP JP2025191616A patent/JP2026015456A/ja active Pending
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