JP2018515503A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018515503A5 JP2018515503A5 JP2017558025A JP2017558025A JP2018515503A5 JP 2018515503 A5 JP2018515503 A5 JP 2018515503A5 JP 2017558025 A JP2017558025 A JP 2017558025A JP 2017558025 A JP2017558025 A JP 2017558025A JP 2018515503 A5 JP2018515503 A5 JP 2018515503A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- thiazolo
- oxathiolan
- pyrimidin
- dioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2015078578 | 2015-05-08 | ||
| CNPCT/CN2015/078578 | 2015-05-08 | ||
| PCT/EP2016/059949 WO2016180691A1 (en) | 2015-05-08 | 2016-05-04 | Novel oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018515503A JP2018515503A (ja) | 2018-06-14 |
| JP2018515503A5 true JP2018515503A5 (enExample) | 2019-06-06 |
| JP6779232B2 JP6779232B2 (ja) | 2020-11-04 |
Family
ID=55910268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558025A Expired - Fee Related JP6779232B2 (ja) | 2015-05-08 | 2016-05-04 | ウイルス感染の治療又は予防のための新規オキサチオランカルボン酸と誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10183954B2 (enExample) |
| EP (1) | EP3294745B1 (enExample) |
| JP (1) | JP6779232B2 (enExample) |
| CN (1) | CN107743491B (enExample) |
| WO (1) | WO2016180691A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021009496A (es) | 2019-02-08 | 2021-09-08 | Progeneer Inc | Complejo de colesterol-agonista del receptor 7 u 8 tipo larga distancia, y uso del mismo. |
| JP2023516372A (ja) | 2020-03-02 | 2023-04-19 | プロジェニア インコーポレイテッド | 病原菌外壁成分基盤の生病原体模倣ナノ粒子及びその製造方法 |
| JP2023536954A (ja) | 2020-08-04 | 2023-08-30 | プロジェニア インコーポレイテッド | 活性化部位が一時的に不活性化したトール様受容体７または８作用薬と機能性薬物の結合体およびその用途 |
| JP7690222B2 (ja) | 2020-08-04 | 2025-06-10 | プロジェニア インコーポレイテッド | 動力学的制御が可能なアジュバントを含むｍＲＮＡワクチン |
| EP4194008A4 (en) | 2020-08-04 | 2025-01-08 | Progeneer Inc. | Kinetically acting adjuvant ensemble |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476659A (en) | 1982-11-09 | 1995-12-19 | The Scripps Research Institute | Cancerous B cell treatment using substituted nucleoside derivatives |
| US5166141A (en) | 1983-11-01 | 1992-11-24 | Scripps Clinic And Research Foundation | Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals |
| US5041426A (en) | 1987-12-21 | 1991-08-20 | Brigham Young University | Immune system enhancing 3-β-d-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and nucleotides |
| US5248776A (en) * | 1990-12-05 | 1993-09-28 | University Of Georgia Research Foundation, Inc. | Process for enantiomerically pure β-L-1,3-oxathiolane nucleosides |
| EP1072607A3 (en) | 1996-10-16 | 2001-09-12 | ICN Pharmaceuticals, Inc. | Purine L-nucleosides, analogs and uses therof |
| CA2266889A1 (en) | 1996-10-16 | 1998-04-23 | Guangyi Wang | Purine l-nucleosides, analogs and uses thereof |
| EP1382343B1 (en) * | 1998-11-02 | 2010-02-17 | Gilead Sciences, Inc. | Combination therapy to treat hepatitis B virus |
| EP1411954B1 (en) * | 2000-10-18 | 2010-12-15 | Pharmasset, Inc. | Modified nucleosides for treatment of viral infections and abnormal cellular proliferation |
| AU2002329970A1 (en) * | 2001-09-04 | 2003-03-18 | Isis Pharmaceuticals, Inc. | Pyrrolo(2,3-d)pyrimidines for inhibiting rna-dependent rna viral polymerase |
| US20050004144A1 (en) | 2003-04-14 | 2005-01-06 | Regents Of The University Of California | Combined use of IMPDH inhibitors with toll-like receptor agonists |
| WO2005025583A2 (en) | 2003-09-05 | 2005-03-24 | Anadys Pharmaceuticals, Inc. | Tlr7 ligands for the treatment of hepatitis c |
| CN101212968B (zh) * | 2004-12-17 | 2011-11-16 | 安那迪斯药品股份有限公司 | 3,5-二取代的和3,5,7-三取代的-3H-噁唑并以及3H-噻唑并[4,5-d]嘧啶-2-酮化合物及其前药 |
| KR101320008B1 (ko) | 2004-12-17 | 2013-10-18 | 애나디스 파마슈티칼스, 인코포레이티드 | ３，５-이치환 및 ３，５，７-삼치환된-３Ｈ-옥사졸로 및３Ｈ-티아졸로 〔４，５-ｄ〕피리미딘-2-온 화합물 및 이의전구약물 |
| AR053347A1 (es) * | 2005-04-06 | 2007-05-02 | Astrazeneca Ab | Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos |
| CL2007001427A1 (es) | 2006-05-22 | 2008-05-16 | Novartis Ag | Sal de maleato de 5-amino-3-(2',3'-di-o-acetil-beta-d-ribofuranosil)-3h-tiazolo[4,5-d]pirimidin-2-ona; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de una infeccion po |
| KR101461604B1 (ko) | 2006-06-22 | 2014-11-18 | 애나디스 파마슈티칼스, 인코포레이티드 | 5-아미노-3-(3''-데옥시-β-Ｄ-리보퓨라노실)-티아졸로［4,5-ｄ］파이리미딘-2,7-다이온의 프로드럭 |
| EP2040712B1 (en) | 2006-07-18 | 2011-03-02 | Anadys Pharmaceuticals, Inc. | Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines |
| BRPI0717741A2 (pt) | 2006-10-17 | 2014-04-08 | Anadys Pharmaceuticals Inc | Compostos e respectivos método de preparação, método de redução de composto de sulfonil substituído, composição farmacêutica método de tratamento ou prevenção de doença |
| WO2009026292A1 (en) | 2007-08-20 | 2009-02-26 | Anadys Pharmaceuticals, Inc. | Dosing methods for treating disease |
| UA111640C2 (uk) * | 2011-11-08 | 2016-05-25 | Ф. Хоффманн-Ля Рош Аг | ПОХІДНІ [1,2,3]ТРИАЗОЛО[4,5-d]ПІРИМІДИНУ ЯК АГОНІСТИ КАНАБІНОЇДНОГО РЕЦЕПТОРА 2 |
| CN104230952B (zh) * | 2014-08-16 | 2017-02-01 | 沈阳药科大学 | 含有嘧啶骨架的化合物及其制备方法和用途 |
| CN107001386A (zh) * | 2014-10-11 | 2017-08-01 | 豪夫迈·罗氏有限公司 | 用于治疗感染性疾病的化合物 |
-
2016
- 2016-05-04 EP EP16720138.3A patent/EP3294745B1/en active Active
- 2016-05-04 JP JP2017558025A patent/JP6779232B2/ja not_active Expired - Fee Related
- 2016-05-04 WO PCT/EP2016/059949 patent/WO2016180691A1/en not_active Ceased
- 2016-05-04 CN CN201680026218.1A patent/CN107743491B/zh not_active Expired - Fee Related
-
2017
- 2017-11-08 US US15/806,635 patent/US10183954B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018515503A5 (enExample) | ||
| JP2017537158A5 (enExample) | ||
| JP2018528244A5 (enExample) | ||
| JP2017515844A5 (enExample) | ||
| JP2014500861A5 (enExample) | ||
| JP2011513410A5 (enExample) | ||
| RU2011146059A (ru) | Конденсированное пирролопиридиновое производное | |
| JP2010138190A5 (enExample) | ||
| JP2010523522A5 (enExample) | ||
| JP2009538910A5 (enExample) | ||
| HRP20210454T1 (hr) | 3-supstituirani 5-amino-6h-tiazolo[4,5-d]pirimidin-2,7-dion spojevi za liječenje i profilaksu virusne infekcije | |
| JP2017531038A5 (enExample) | ||
| JP2020507589A5 (enExample) | ||
| JP2013508279A5 (enExample) | ||
| JP2015514063A5 (enExample) | ||
| JP2013508373A5 (enExample) | ||
| JP2009143956A5 (enExample) | ||
| JP2012523457A5 (enExample) | ||
| JP2012504133A5 (enExample) | ||
| JP2013512277A5 (enExample) | ||
| JP2020505354A5 (enExample) | ||
| JP2014526554A5 (enExample) | ||
| JP2006511490A5 (enExample) | ||
| JP2018529671A5 (enExample) | ||
| JP2011523952A5 (enExample) |