|
US1910220A
(en)
*
|
1931-10-21 |
1933-05-23 |
Kremser Alois |
Mechanically operated gate
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
|
US5994618A
(en)
|
1997-02-05 |
1999-11-30 |
Johns Hopkins University School Of Medicine |
Growth differentiation factor-8 transgenic mice
|
|
EP1333035A3
(en)
|
1993-03-19 |
2004-07-07 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor-8
|
|
US6368597B1
(en)
|
1998-05-06 |
2002-04-09 |
Matamorphix, Inc. |
Methods of treating diabetes
|
|
US6927044B2
(en)
|
1998-09-25 |
2005-08-09 |
Regeneron Pharmaceuticals, Inc. |
IL-1 receptor based cytokine traps
|
|
CN1384757A
(zh)
|
1999-07-20 |
2002-12-11 |
法麦克萨有限公司 |
下调gdf－8活性的方法
|
|
US6670140B2
(en)
|
2001-03-06 |
2003-12-30 |
The Procter & Gamble Company |
Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
|
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US7241444B2
(en)
|
2002-01-18 |
2007-07-10 |
Pierre Fabre Medicament |
Anti-IGF-IR antibodies and uses thereof
|
|
US7261893B2
(en)
|
2002-10-22 |
2007-08-28 |
Wyeth |
Neutralizing antibodies against GDF-8 and uses therefor
|
|
US20040101920A1
(en)
|
2002-11-01 |
2004-05-27 |
Czeslaw Radziejewski |
Modification assisted profiling (MAP) methodology
|
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
|
MXPA05012965A
(es)
|
2003-06-02 |
2006-03-09 |
Wyeth Corp |
Uso de inhibidores de miostatina (gdf8) en conjuncion con corticoesteroides para el tratamiento de desordenes neuromusculares y composiciones farmaceuticas para ello.
|
|
WO2005066204A2
(en)
|
2003-12-31 |
2005-07-21 |
Schering-Plough Ltd. |
Neutralizing epitope-based growth enhancing vaccine
|
|
AU2005219441A1
(en)
|
2004-03-02 |
2005-09-15 |
Acceleron Pharma Inc. |
ALK7 and myostatin inhibitors and uses thereof
|
|
ATE557042T1
(de)
|
2004-03-23 |
2012-05-15 |
Lilly Co Eli |
Anti-myostatin-antikörper
|
|
EP1740946B1
(en)
|
2004-04-20 |
2013-11-06 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
AU2005272646A1
(en)
|
2004-08-12 |
2006-02-23 |
Wyeth |
Combination therapy for diabetes, obesity, and cardiovascular diseases using GDF-8 inhibitors
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
AU2006239860B2
(en)
|
2005-04-25 |
2012-01-19 |
Amgen Fremont Inc. |
Antibodies to myostatin
|
|
JP5065253B2
(ja)
|
2005-05-06 |
2012-10-31 |
ザイモジェネティクス， インコーポレイテッド |
Ｉｌ−３１モノクローナル抗体とその使用法
|
|
EP1773041A1
(en)
|
2005-07-21 |
2007-04-11 |
Chao-Hung Wu |
Audio/video data transmission system using the internet to interconnect telephones
|
|
MX2008002367A
(es)
|
2005-08-19 |
2008-03-18 |
Wyeth Corp |
Anticuerpos antagonistas contra el factor 8 de crecimiento y diferenciacion y usos en el tratamiento de esclerosis lateral amiotrofica y otros trastornos relacionados con el factor 8 de crecimiento y diferenciacion.
|
|
US7635760B2
(en)
|
2005-10-06 |
2009-12-22 |
Eli Lilly And Company |
Anti-myostatin antibodies
|
|
UA92504C2
(en)
*
|
2005-10-12 |
2010-11-10 |
Эли Лилли Энд Компани |
Anti-myostatin monoclonal antibody
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
US20070149458A1
(en)
|
2005-12-06 |
2007-06-28 |
Amgen Inc. |
Uses of myostatin antagonists
|
|
MY159787A
(en)
|
2006-06-02 |
2017-01-31 |
Regeneron Pharma |
High affinity antibodies to human il-6 receptor
|
|
EP2054434B1
(en)
|
2006-08-03 |
2017-03-15 |
Myostin Therapeutics Pty Ltd |
Myostatin antagonists
|
|
UA98308C2
(en)
|
2006-09-05 |
2012-05-10 |
Эли Лилли Энд Компани |
Anti-myostatin antibody
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
TWI573802B
(zh)
|
2007-03-06 |
2017-03-11 |
安美基公司 |
變異之活動素受體多肽及其用途
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
AR069165A1
(es)
|
2007-11-05 |
2010-01-06 |
Novartis Ag |
Derivados de 4-bencilamino-1-carboxacilpiperidina como inhibidores de cetp utiles para el tratamiento de hiperlipidemia
|
|
WO2010019261A1
(en)
|
2008-08-14 |
2010-02-18 |
Acceleron Pharma Inc. |
Use of gdf traps to increase red blood cell levels
|
|
TW201029662A
(en)
*
|
2008-12-19 |
2010-08-16 |
Glaxo Group Ltd |
Novel antigen binding proteins
|
|
EP2387412A4
(en)
|
2009-01-13 |
2013-04-03 |
Acceleron Pharma Inc |
PROCESS FOR INCREASING THE ADIPONECTIN MIRROR
|
|
DK2424895T3
(en)
|
2009-04-27 |
2017-12-18 |
Novartis Ag |
Compositions and Methods for Increasing Muscle Growth
|
|
KR20120027055A
(ko)
|
2009-06-26 |
2012-03-20 |
리제네론 파라마큐티칼스 인코포레이티드 |
천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체
|
|
JP6267425B2
(ja)
|
2009-11-17 |
2018-01-24 |
アクセルロン ファーマ， インコーポレイテッド |
筋ジストロフィー治療のためのユートロフィン誘導に関するａｃｔｒｉｉｂタンパク質およびその改変体およびその使用
|
|
JO3340B1
(ar)
*
|
2010-05-26 |
2019-03-13 |
Regeneron Pharma |
مضادات حيوية لـعامل تمايز النمو 8 البشري
|
|
TW201210612A
(en)
|
2010-06-03 |
2012-03-16 |
Glaxo Group Ltd |
Humanised antigen binding proteins
|
|
EA201390242A1
(ru)
|
2010-08-16 |
2013-07-30 |
Амген Инк. |
Антитела, связывающие миостатин, композиции и способы
|
|
AU2011326586A1
(en)
|
2010-11-08 |
2013-05-30 |
Acceleron Pharma, Inc. |
ActRIIA binding agents and uses thereof
|
|
EP3824890A1
(en)
|
2011-05-16 |
2021-05-26 |
Genzyme Corporation |
Induction of immune tolerance using methotrexate
|
|
DK2780368T3
(en)
|
2011-11-14 |
2018-02-05 |
Regeneron Pharma |
COMPOSITIONS AND PROCEDURES FOR INCREASING MUSCLE MASS AND MUSCLE STRENGTH BY SPECIFIC ANTAGONIZATION OF GDF8 AND / OR ACTIVIN A
|
|
GR1007832B
(el)
|
2011-11-21 |
2013-02-14 |
Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, |
Αδρανοποιητες της ακτιβινης και χρηση τους για την θεραπεια ασθενειων που σχετιζονται με παρεκκλινουσα ενεργοποιηση της "αμυντικης αποκρισης του ξενιστη"
|
|
NZ702269A
(en)
|
2012-06-15 |
2017-07-28 |
Pfizer |
Improved antagonist antibodies against gdf-8 and uses therefor
|
|
WO2014022540A1
(en)
|
2012-08-02 |
2014-02-06 |
Regeneron Pharmaceuticals, Inc. |
Multivalent antigen-binding proteins
|
|
EA201591423A1
(ru)
|
2013-02-01 |
2016-01-29 |
Санта Мария Биотерапевтикс, Инк. |
Введение антитела к активину-а пациентам
|
|
TWI655207B
(zh)
|
2013-07-30 |
2019-04-01 |
再生元醫藥公司 |
抗活化素ａ之抗體及其用途
|
|
CN105960414A
(zh)
*
|
2013-08-14 |
2016-09-21 |
诺华股份有限公司 |
治疗散发性包涵体肌炎的方法
|
|
US20160075772A1
(en)
|
2014-09-12 |
2016-03-17 |
Regeneron Pharmaceuticals, Inc. |
Treatment of Fibrodysplasia Ossificans Progressiva
|
|
MX2017013267A
(es)
|
2015-04-15 |
2018-08-15 |
Regeneron Pharma |
Metodos para aumentar la fuerza y funcionalidad con inhibidores del factor de diferenciacion y crecimiento 8 (gdf8).
|
|
WO2018009732A1
(en)
|
2016-07-08 |
2018-01-11 |
Regeneron Pharmaceuticals, Inc. |
Anti-activin a antibodies and methods of use thereof for treating pulmonary arterial hypertension
|
|
JP7579706B2
(ja)
|
2018-03-01 |
2024-11-08 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
体組成を変更するための方法
|