JP2018511659A5 - - Google Patents
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- Publication number
- JP2018511659A5 JP2018511659A5 JP2018505505A JP2018505505A JP2018511659A5 JP 2018511659 A5 JP2018511659 A5 JP 2018511659A5 JP 2018505505 A JP2018505505 A JP 2018505505A JP 2018505505 A JP2018505505 A JP 2018505505A JP 2018511659 A5 JP2018511659 A5 JP 2018511659A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- vaccine composition
- adjuvant
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 20
- 229960005486 vaccine Drugs 0.000 claims 20
- 239000002671 adjuvant Substances 0.000 claims 14
- 230000004927 fusion Effects 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 125000003275 alpha amino acid group Chemical group 0.000 claims 12
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- 102000014914 Carrier Proteins Human genes 0.000 claims 4
- 108010078791 Carrier Proteins Proteins 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 101150029707 ERBB2 gene Proteins 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 230000014509 gene expression Effects 0.000 claims 2
- 230000002018 overexpression Effects 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 102000016607 Diphtheria Toxin Human genes 0.000 claims 1
- 108010053187 Diphtheria Toxin Proteins 0.000 claims 1
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 claims 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims 1
- 229940103272 aluminum potassium sulfate Drugs 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 claims 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015901375A AU2015901375A0 (en) | 2015-04-17 | A vaccine composition and uses thereof | |
| AU2015901375 | 2015-04-17 | ||
| PCT/AU2016/050275 WO2016164980A1 (en) | 2015-04-17 | 2016-04-15 | A vaccine composition and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511659A JP2018511659A (ja) | 2018-04-26 |
| JP2018511659A5 true JP2018511659A5 (enExample) | 2019-05-23 |
| JP6957448B2 JP6957448B2 (ja) | 2021-11-02 |
Family
ID=57125491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505505A Active JP6957448B2 (ja) | 2015-04-17 | 2016-04-15 | ワクチン組成物およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10532090B2 (enExample) |
| EP (1) | EP3283105B1 (enExample) |
| JP (1) | JP6957448B2 (enExample) |
| KR (1) | KR102372615B1 (enExample) |
| CN (1) | CN108025061B (enExample) |
| AU (1) | AU2016250289B2 (enExample) |
| ES (1) | ES2908071T3 (enExample) |
| NZ (1) | NZ736194A (enExample) |
| RS (1) | RS63080B1 (enExample) |
| RU (1) | RU2726411C2 (enExample) |
| SG (1) | SG11201708247XA (enExample) |
| TW (1) | TWI740823B (enExample) |
| WO (1) | WO2016164980A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210346484A1 (en) * | 2017-12-11 | 2021-11-11 | Medizinische Universitaet Wien | Method of producing a vaccine composition and uses thereof |
| CA3090552A1 (en) * | 2018-02-07 | 2019-08-15 | Imugene Limited | A vaccine composition and uses thereof |
| WO2022133447A1 (en) * | 2020-12-16 | 2022-06-23 | Dynavax Technologies Corporation | Method for quantifying cpg-containing oligonucleotides in formulations comprising alum |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0739984A1 (en) * | 1995-04-26 | 1996-10-30 | San Tumorforschungs-Gmbh | Bivalent polypeptides containing at least two domains |
| GB9808932D0 (en) * | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
| JP4658423B2 (ja) * | 1999-08-03 | 2011-03-23 | ザ オハイオ ステイト ユニバーシティ | Ｈｅｒ−２タンパク質に対する免疫反応性を増強するためのポリペプチドおよびポリヌクレオチド |
| EP1236740B1 (de) | 2001-02-28 | 2012-07-18 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | Vakzine gegen Krebserkrankungen, die mit dem HER-2/neu Onkogen assoziiert sind |
| WO2005021710A2 (en) * | 2003-06-02 | 2005-03-10 | University Of Miami | Chimeric molecules and methods of use |
| EP1844788B1 (en) | 2006-04-13 | 2010-07-14 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | HER-2/neu multi-peptide vaccine |
| EP2292258A1 (en) * | 2009-08-18 | 2011-03-09 | Pevion Biotech Ltd. | Multiepitope vaccine for Her2/neu-associated cancers |
| EP2659906A1 (en) * | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
| ES2528109T3 (es) * | 2012-05-31 | 2015-02-04 | Innavirvax | Compuestos inmunogénicos que comprenden péptido gp41 de VIH acoplado a proteína portadora CRM197 |
| EP3166646A4 (en) * | 2014-07-07 | 2018-03-07 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
-
2016
- 2016-04-15 RS RS20220204A patent/RS63080B1/sr unknown
- 2016-04-15 RU RU2017137502A patent/RU2726411C2/ru active
- 2016-04-15 JP JP2018505505A patent/JP6957448B2/ja active Active
- 2016-04-15 TW TW105111976A patent/TWI740823B/zh active
- 2016-04-15 CN CN201680029118.4A patent/CN108025061B/zh active Active
- 2016-04-15 EP EP16779340.5A patent/EP3283105B1/en active Active
- 2016-04-15 AU AU2016250289A patent/AU2016250289B2/en active Active
- 2016-04-15 NZ NZ736194A patent/NZ736194A/en unknown
- 2016-04-15 US US15/316,868 patent/US10532090B2/en active Active
- 2016-04-15 SG SG11201708247XA patent/SG11201708247XA/en unknown
- 2016-04-15 KR KR1020177032987A patent/KR102372615B1/ko active Active
- 2016-04-15 ES ES16779340T patent/ES2908071T3/es active Active
- 2016-04-15 WO PCT/AU2016/050275 patent/WO2016164980A1/en not_active Ceased
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