JP2018511556A5 - - Google Patents
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- JP2018511556A5 JP2018511556A5 JP2017538686A JP2017538686A JP2018511556A5 JP 2018511556 A5 JP2018511556 A5 JP 2018511556A5 JP 2017538686 A JP2017538686 A JP 2017538686A JP 2017538686 A JP2017538686 A JP 2017538686A JP 2018511556 A5 JP2018511556 A5 JP 2018511556A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022010930A JP2022044770A (ja) | 2015-01-22 | 2022-01-27 | ｉｎ ｖｉｖｏ画像化のためのプロテアーゼ活性化コントラスト剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562106400P | 2015-01-22 | 2015-01-22 | |
| US62/106,400 | 2015-01-22 | ||
| PCT/US2016/014606 WO2016118910A1 (en) | 2015-01-22 | 2016-01-22 | Protease-activated contrast agents for in vivo imaging |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022010930A Division JP2022044770A (ja) | 2015-01-22 | 2022-01-27 | ｉｎ ｖｉｖｏ画像化のためのプロテアーゼ活性化コントラスト剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511556A JP2018511556A (ja) | 2018-04-26 |
| JP2018511556A5 true JP2018511556A5 (https=) | 2019-03-07 |
| JP7017410B2 JP7017410B2 (ja) | 2022-02-08 |
Family
ID=56417841
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538686A Active JP7017410B2 (ja) | 2015-01-22 | 2016-01-22 | ｉｎ ｖｉｖｏ画像化のためのプロテアーゼ活性化コントラスト剤 |
| JP2022010930A Pending JP2022044770A (ja) | 2015-01-22 | 2022-01-27 | ｉｎ ｖｉｖｏ画像化のためのプロテアーゼ活性化コントラスト剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022010930A Pending JP2022044770A (ja) | 2015-01-22 | 2022-01-27 | ｉｎ ｖｉｖｏ画像化のためのプロテアーゼ活性化コントラスト剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10570173B2 (https=) |
| EP (1) | EP3247802B1 (https=) |
| JP (2) | JP7017410B2 (https=) |
| KR (1) | KR102668593B1 (https=) |
| CN (1) | CN107406872B (https=) |
| WO (1) | WO2016118910A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10570173B2 (en) * | 2015-01-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protease-activated contrast agents for in vivo imaging |
| US10405753B2 (en) * | 2015-11-10 | 2019-09-10 | Intuitive Surgical Operations, Inc. | Pharmaceutical compositions of near IR closed chain, sulfo-cyanine dyes |
| GB201617935D0 (en) | 2016-10-24 | 2016-12-07 | Queens University Of Belfast The | Binding compound and uses thereof |
| JP6984909B2 (ja) * | 2016-12-23 | 2021-12-22 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 活性ベースのプローブ化合物、組成物、および使用方法 |
| KR102669535B1 (ko) * | 2017-03-30 | 2024-05-24 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 생체 내 이미징을 위한 프로테아제 활성화 조영제 |
| US20220105206A1 (en) * | 2020-10-02 | 2022-04-07 | Board Of Regents, The University Of Texas System | Sensitivity advances in ultrasound switchable fluorescence systems and techniques |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL60888A (en) * | 1978-06-16 | 1984-07-31 | Yeda Res & Dev | Substrates and process for the quantitative assay of enzymes |
| WO1996041638A1 (en) | 1995-06-13 | 1996-12-27 | Sanofi Winthrop, Inc. | Calpain inhibitors for the treatment of neurodegenerative diseases |
| US7303741B2 (en) | 2002-09-23 | 2007-12-04 | General Electric Company | Systems and methods for high-resolution in vivo imaging of biochemical activity in a living organism |
| US8133482B2 (en) * | 2003-11-14 | 2012-03-13 | The Trustees Of The University Of Pennsylvania | Activatable photodynamic therapy agents |
| JP2008522624A (ja) | 2004-12-09 | 2008-07-03 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘミアスタリン（ｈｅｍｉａｓｔｅｒｌｉｎ）アナログを使用する癌治療におけるチューブリンのアイソタイプのスクリーニング |
| US8968700B2 (en) * | 2005-08-11 | 2015-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Imaging of protease activity in live cells using activity based probes |
| EP2020988B1 (en) | 2006-04-28 | 2017-08-16 | Children's Hospital Medical Center | Compositions comprising fusogenic proteins or polypeptides derived from prosaposin for application in transmembrane drug delivery systems |
| CN101652149B (zh) * | 2007-02-28 | 2012-11-14 | 塞诺菲-安万特股份有限公司 | 成像探针 |
| WO2008104271A2 (en) | 2007-02-28 | 2008-09-04 | Sanofi-Aventis | Imaging probes |
| CA2686089A1 (en) * | 2007-05-16 | 2008-11-20 | Ge Healthcare As | Optical imaging agents |
| CN101772577A (zh) * | 2007-08-03 | 2010-07-07 | 塞诺菲-安万特股份有限公司 | 半胱天冬蛋白酶成像探针 |
| US8343458B2 (en) | 2008-04-03 | 2013-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Probes for in vivo targeting of active cysteine proteases |
| WO2010016911A2 (en) * | 2008-08-06 | 2010-02-11 | The Texas A & M University System | Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics |
| WO2010053489A1 (en) | 2008-11-07 | 2010-05-14 | Children's Hospital Medical Center | Fusogenic properties of saposin c and related proteins and peptides for application to transmembrane drug delivery systems |
| US9155471B2 (en) * | 2009-05-27 | 2015-10-13 | Lumicell, Inc'. | Methods and systems for spatially identifying abnormal cells |
| WO2012021800A2 (en) | 2010-08-13 | 2012-02-16 | Banyan Biomarkers | Caspase inhibitors as therapeutics for neural and organ injury and imaging |
| WO2012118715A2 (en) | 2011-02-28 | 2012-09-07 | The Board Of Trustees Of Leland Stanford Junior University | Non-peptidic quenched fluorescent imaging probes |
| EP2686680B1 (en) * | 2011-03-18 | 2018-06-13 | Biotium Inc. | Fluorescent dyes, fluorescent dye kits, and methods of preparing labeled molecules |
| US20140249468A1 (en) * | 2011-09-09 | 2014-09-04 | The United States Of America,As Represented By The Secretary, Department Of Health And Human Service | Imaging agents for imaging protease activity and uses thereof |
| US20140180073A1 (en) * | 2012-12-24 | 2014-06-26 | Anticancer, Inc. | Portable digital imaging system for fluorescence-guided surgery |
| US9763577B2 (en) | 2013-03-14 | 2017-09-19 | Lumicell, Inc. | Imaging agent for detection of diseased cells |
| EP4218829A3 (en) | 2013-03-15 | 2023-08-16 | The Board of Trustees of the Leland Stanford Junior University | Activity-based probe compounds, compositions, and methods of use |
| SG11201508185YA (en) * | 2013-04-19 | 2015-11-27 | Agency Science Tech & Res | Tunable fluorescence using cleavable linkers |
| US10570173B2 (en) * | 2015-01-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protease-activated contrast agents for in vivo imaging |
| KR102669535B1 (ko) * | 2017-03-30 | 2024-05-24 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 생체 내 이미징을 위한 프로테아제 활성화 조영제 |
-
2016
- 2016-01-22 US US15/545,689 patent/US10570173B2/en active Active
- 2016-01-22 JP JP2017538686A patent/JP7017410B2/ja active Active
- 2016-01-22 CN CN201680017762.XA patent/CN107406872B/zh active Active
- 2016-01-22 KR KR1020177023302A patent/KR102668593B1/ko active Active
- 2016-01-22 EP EP16740869.9A patent/EP3247802B1/en active Active
- 2016-01-22 WO PCT/US2016/014606 patent/WO2016118910A1/en not_active Ceased
-
2020
- 2020-02-14 US US16/792,142 patent/US20200299327A1/en not_active Abandoned
-
2022
- 2022-01-27 JP JP2022010930A patent/JP2022044770A/ja active Pending
- 2022-11-08 US US18/053,682 patent/US12459972B2/en active Active
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