JP2018511466A5 - - Google Patents
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- JP2018511466A5 JP2018511466A5 JP2017549017A JP2017549017A JP2018511466A5 JP 2018511466 A5 JP2018511466 A5 JP 2018511466A5 JP 2017549017 A JP2017549017 A JP 2017549017A JP 2017549017 A JP2017549017 A JP 2017549017A JP 2018511466 A5 JP2018511466 A5 JP 2018511466A5
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- 239000012530 fluid Substances 0.000 claims 33
- 238000000034 method Methods 0.000 claims 15
- 238000004945 emulsification Methods 0.000 claims 13
- 239000007788 liquid Substances 0.000 claims 4
- 239000000839 emulsion Substances 0.000 claims 3
- 239000003995 emulsifying agent Substances 0.000 claims 2
- 230000001804 emulsifying effect Effects 0.000 claims 2
- 230000002209 hydrophobic effect Effects 0.000 claims 2
- 239000012491 analyte Substances 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562133621P | 2015-03-16 | 2015-03-16 | |
| US62/133,621 | 2015-03-16 | ||
| US201562269289P | 2015-12-18 | 2015-12-18 | |
| US62/269,289 | 2015-12-18 | ||
| PCT/US2016/022418 WO2016149241A1 (en) | 2015-03-16 | 2016-03-15 | Apparatus and methods for multi-step channel emulsification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511466A JP2018511466A (ja) | 2018-04-26 |
| JP2018511466A5 true JP2018511466A5 (enExample) | 2018-11-15 |
| JP6726680B2 JP6726680B2 (ja) | 2020-07-22 |
Family
ID=56919341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017549017A Active JP6726680B2 (ja) | 2015-03-16 | 2016-03-15 | 多段チャネル乳化のための装置及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10662470B2 (enExample) |
| EP (1) | EP3271058B1 (enExample) |
| JP (1) | JP6726680B2 (enExample) |
| KR (1) | KR102528348B1 (enExample) |
| CN (1) | CN107427788B (enExample) |
| CA (1) | CA2979415C (enExample) |
| WO (1) | WO2016149241A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016189383A1 (en) * | 2015-05-22 | 2016-12-01 | The Hong Kong University Of Science And Technology | Droplet generator based on high aspect ratio induced droplet self-breakup |
| WO2018062970A1 (ko) * | 2016-09-30 | 2018-04-05 | (주)아모레퍼시픽 | 미세 유체 채널에 기반하여 순간 유화된 유화 물질을 함유하는 화장품 조성물 제조 장치 |
| CN106492716B (zh) * | 2016-12-20 | 2024-01-30 | 中国工程物理研究院激光聚变研究中心 | 一体式双重乳粒发生装置及其加工方法 |
| JP7071056B2 (ja) * | 2017-02-27 | 2022-05-18 | シスメックス株式会社 | 液体送液方法および液体送液装置 |
| WO2018213643A1 (en) | 2017-05-18 | 2018-11-22 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
| US10544413B2 (en) | 2017-05-18 | 2020-01-28 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
| US10549279B2 (en) | 2017-08-22 | 2020-02-04 | 10X Genomics, Inc. | Devices having a plurality of droplet formation regions |
| WO2019083852A1 (en) | 2017-10-26 | 2019-05-02 | 10X Genomics, Inc. | MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING |
| CN112399882B (zh) * | 2018-04-16 | 2023-08-01 | 派特恩生物技术有限公司 | 用于形成二维微滴阵列的方法和设备 |
| US11130120B2 (en) | 2018-10-01 | 2021-09-28 | Lifeng XIAO | Micro-pipette tip for forming micro-droplets |
| US10486155B1 (en) | 2018-10-22 | 2019-11-26 | Klaris Corporation | Vacuum-loaded, droplet-generating microfluidic chips and related methods |
| EP3930900A1 (en) | 2019-02-28 | 2022-01-05 | 10X Genomics, Inc. | Devices, systems, and methods for increasing droplet formation efficiency |
| CN110075934B (zh) * | 2019-03-25 | 2021-06-01 | 绍兴钠钇光电有限公司 | 一种3d打印微流控器件及其大通量制备单分散乳液的方法 |
| PT3721980T (pt) * | 2019-04-12 | 2022-10-13 | Ecole Superieure Physique & Chimie Ind Ville De Paris | Dispositivo microfluídico de produção de emulsão |
| JP7157263B2 (ja) * | 2019-07-01 | 2022-10-19 | オークウッド ラボラトリーズ，エル．エル．シー． | ミクロスフェア及びエマルションを製造するためのシステム及び方法 |
| US11919002B2 (en) | 2019-08-20 | 2024-03-05 | 10X Genomics, Inc. | Devices and methods for generating and recovering droplets |
| WO2021035009A1 (en) * | 2019-08-20 | 2021-02-25 | Pattern Bioscience, Inc. | Methods for screening and subsequent processing of samples taken from non-sterile sites |
| US20210053064A1 (en) * | 2019-08-20 | 2021-02-25 | Pattern Bioscience, Inc. | Microfluidic Chips Including a Gutter to Facilitate Loading Thereof and Related Methods |
| US10953404B1 (en) | 2020-04-24 | 2021-03-23 | Pattern Bioscience, Inc. | Apparatuses for contactless loading and imaging of microfluidic chips and related methods |
| US12415182B2 (en) | 2020-10-19 | 2025-09-16 | Pattern Bioscience, Inc. | Microfluidic chips including a gutter having a trough and a ridge to facilitate loading thereof and related methods |
| EP3991847A1 (en) * | 2020-10-27 | 2022-05-04 | Shenzhen Biorain Biotechnology Co., Ltd. | Microfluidic chip |
| US12186722B2 (en) | 2022-02-07 | 2025-01-07 | Honeywell Federal Manufacturing & Technologies, Llc | Porous polysiloxane microspheres |
| GB2625341A (en) * | 2022-12-14 | 2024-06-19 | Lightcast Discovery Ltd | Improvements in or relating to a cartridge |
| CN116179341A (zh) * | 2023-03-15 | 2023-05-30 | 河南农业大学 | 一种适用于细菌芽孢快速分离纯化的“阶梯式”自动装置、制备方法及应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1142002A (en) | 1965-03-24 | 1969-02-05 | Fisons Ltd | Granulation |
| US3713780A (en) * | 1971-02-01 | 1973-01-30 | Becton Dickinson Co | Apparatus for chemical testing |
| US5455315A (en) * | 1994-06-06 | 1995-10-03 | Xerox Corporation | Emulsion polymerization processes and toners thereof |
| FR2747321B1 (fr) * | 1996-04-16 | 1998-07-10 | Centre Nat Rech Scient | Procede de preparation d'une emulsion |
| AU2002320576A1 (en) * | 2001-07-17 | 2003-03-03 | Paolo Gasparini | Microstructure for particle and cell separation, identification, sorting, and manipulation |
| JP4520166B2 (ja) * | 2004-02-02 | 2010-08-04 | 独立行政法人農業・食品産業技術総合研究機構 | 樹脂製マイクロチャネル基板及びその製造方法 |
| US20060120213A1 (en) * | 2004-11-17 | 2006-06-08 | Tonkovich Anna L | Emulsion process using microchannel process technology |
| DE102005037401B4 (de) | 2005-08-08 | 2007-09-27 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Bildung einer Emulsion in einem fluidischen Mikrosystem |
| WO2007136328A1 (en) * | 2006-05-18 | 2007-11-29 | Marilyn Rayner | Manufacturing method of a membrane and a membrane thereof, for emulsification |
| DE102006036815B4 (de) | 2006-08-07 | 2010-01-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Emulgiereinrichtung und Verfahren zur Bildung einer Emulsion |
| JP5157629B2 (ja) * | 2008-05-14 | 2013-03-06 | ソニー株式会社 | 流路基板 |
| US20140024023A1 (en) * | 2012-07-23 | 2014-01-23 | Bio- Rad Laboratories, Inc | Droplet generation system with features for sample positioning |
| US9598725B2 (en) * | 2010-03-02 | 2017-03-21 | Bio-Rad Laboratories, Inc. | Emulsion chemistry for encapsulated droplets |
| US9464319B2 (en) | 2009-03-24 | 2016-10-11 | California Institute Of Technology | Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes |
| EP2451575A2 (en) * | 2009-07-07 | 2012-05-16 | Boehringer Ingelheim Microparts GmbH | Plasma separation reservoir |
| FR2950544B1 (fr) | 2009-09-29 | 2011-12-09 | Ecole Polytech | Circuit microfluidique |
| US20110236277A1 (en) * | 2010-03-24 | 2011-09-29 | Electronics And Telecommunications Research Institute | Microfluid control device and method of manufacturing the same |
| FR2958186A1 (fr) | 2010-03-30 | 2011-10-07 | Ecole Polytech | Dispositif de formation de gouttes dans un circuit microfluide. |
| BR112013029729A2 (pt) * | 2011-05-23 | 2017-01-24 | Basf Se | controle de emulsões, incluindo emulsões múltiplas |
| US8944083B2 (en) | 2011-06-15 | 2015-02-03 | Ut-Battelle, Llc | Generation of monodisperse droplets by shape-induced shear and interfacial controlled fusion of individual droplets on-demand |
| GB201121541D0 (en) * | 2011-12-14 | 2012-01-25 | Maelstrom Advanced Process Technologies Ltd | Improved dynamic mixer |
| US9475013B2 (en) | 2012-02-08 | 2016-10-25 | President And Fellows Of Harvard College | Droplet formation using fluid breakup |
| DE102013200927A1 (de) * | 2013-01-22 | 2014-07-24 | Siemens Aktiengesellschaft | Verfahren zum Anreichern und Vereinzeln von Zellen mit Konzentrationen über mehrere logarithmische Stufen |
| US9631179B2 (en) * | 2013-03-15 | 2017-04-25 | Angle North America, Inc. | Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge |
| US10620120B2 (en) * | 2016-06-30 | 2020-04-14 | The University Of North Carolina At Greensboro | Nanoplasmonic devices and applications thereof |
| US20200290048A1 (en) * | 2017-08-22 | 2020-09-17 | 10X Genomics, Inc. | Methods and systems for generating droplets |
| US20190099751A1 (en) * | 2017-09-29 | 2019-04-04 | Regents Of The University Of Minnesota | Compact Open-Channel Microfluidic Diodes Based On Two-Tier Capillary Junctions |
| WO2019118355A1 (en) * | 2017-12-12 | 2019-06-20 | 10X Genomics, Inc. | Systems and methods for single cell processing |
| CN112399882B (zh) * | 2018-04-16 | 2023-08-01 | 派特恩生物技术有限公司 | 用于形成二维微滴阵列的方法和设备 |
| US20210031189A1 (en) * | 2018-10-22 | 2021-02-04 | Pattern Bioscience, Inc. | Droplet-Generating Microfluidic Chips and Related Methods |
-
2016
- 2016-03-15 CN CN201680016472.3A patent/CN107427788B/zh active Active
- 2016-03-15 KR KR1020177029532A patent/KR102528348B1/ko active Active
- 2016-03-15 JP JP2017549017A patent/JP6726680B2/ja active Active
- 2016-03-15 CA CA2979415A patent/CA2979415C/en active Active
- 2016-03-15 US US15/070,108 patent/US10662470B2/en active Active
- 2016-03-15 EP EP16765576.0A patent/EP3271058B1/en active Active
- 2016-03-15 WO PCT/US2016/022418 patent/WO2016149241A1/en not_active Ceased
-
2020
- 2020-04-27 US US16/858,913 patent/US11098351B2/en active Active
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