CA2979415C - Apparatus and methods for multi-step channel emulsification - Google Patents
Apparatus and methods for multi-step channel emulsification Download PDFInfo
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- CA2979415C CA2979415C CA2979415A CA2979415A CA2979415C CA 2979415 C CA2979415 C CA 2979415C CA 2979415 A CA2979415 A CA 2979415A CA 2979415 A CA2979415 A CA 2979415A CA 2979415 C CA2979415 C CA 2979415C
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Classifications
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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| PCT/US2016/022418 WO2016149241A1 (en) | 2015-03-16 | 2016-03-15 | Apparatus and methods for multi-step channel emulsification |
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| CA2979415C true CA2979415C (en) | 2023-08-22 |
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| WO2016189383A1 (en) * | 2015-05-22 | 2016-12-01 | The Hong Kong University Of Science And Technology | Droplet generator based on high aspect ratio induced droplet self-breakup |
| WO2018062970A1 (ko) * | 2016-09-30 | 2018-04-05 | (주)아모레퍼시픽 | 미세 유체 채널에 기반하여 순간 유화된 유화 물질을 함유하는 화장품 조성물 제조 장치 |
| CN106492716B (zh) * | 2016-12-20 | 2024-01-30 | 中国工程物理研究院激光聚变研究中心 | 一体式双重乳粒发生装置及其加工方法 |
| JP7071056B2 (ja) * | 2017-02-27 | 2022-05-18 | シスメックス株式会社 | 液体送液方法および液体送液装置 |
| CN110945139B (zh) | 2017-05-18 | 2023-09-05 | 10X基因组学有限公司 | 用于分选液滴和珠的方法和系统 |
| US10544413B2 (en) | 2017-05-18 | 2020-01-28 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
| US10357771B2 (en) | 2017-08-22 | 2019-07-23 | 10X Genomics, Inc. | Method of producing emulsions |
| WO2019083852A1 (en) | 2017-10-26 | 2019-05-02 | 10X Genomics, Inc. | MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING |
| WO2019204279A1 (en) | 2018-04-16 | 2019-10-24 | Klaris Corporation | Methods and apparatus for forming 2-dimensional drop arrays |
| US11130120B2 (en) | 2018-10-01 | 2021-09-28 | Lifeng XIAO | Micro-pipette tip for forming micro-droplets |
| US10486155B1 (en) * | 2018-10-22 | 2019-11-26 | Klaris Corporation | Vacuum-loaded, droplet-generating microfluidic chips and related methods |
| WO2020176882A1 (en) | 2019-02-28 | 2020-09-03 | 10X Genomics, Inc. | Devices, systems, and methods for increasing droplet formation efficiency |
| CN110075934B (zh) * | 2019-03-25 | 2021-06-01 | 绍兴钠钇光电有限公司 | 一种3d打印微流控器件及其大通量制备单分散乳液的方法 |
| EP3721980B1 (en) * | 2019-04-12 | 2022-07-06 | Paris Sciences et Lettres | Emulsion production microfluidic device |
| EP3993898B1 (en) * | 2019-07-01 | 2025-10-15 | Oakwood Laboratories, Llc | System and method for making microspheres and emulsions |
| WO2021035009A1 (en) * | 2019-08-20 | 2021-02-25 | Pattern Bioscience, Inc. | Methods for screening and subsequent processing of samples taken from non-sterile sites |
| US11919002B2 (en) | 2019-08-20 | 2024-03-05 | 10X Genomics, Inc. | Devices and methods for generating and recovering droplets |
| WO2021035044A1 (en) * | 2019-08-20 | 2021-02-25 | Pattern Bioscience, Inc. | Microfluidic chips including a gutter to facilitate loading thereof and related methods |
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| US12186722B2 (en) | 2022-02-07 | 2025-01-07 | Honeywell Federal Manufacturing & Technologies, Llc | Porous polysiloxane microspheres |
| GB2625341A (en) * | 2022-12-14 | 2024-06-19 | Lightcast Discovery Ltd | Improvements in or relating to a cartridge |
| CN116179341A (zh) * | 2023-03-15 | 2023-05-30 | 河南农业大学 | 一种适用于细菌芽孢快速分离纯化的“阶梯式”自动装置、制备方法及应用 |
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| DE102005037401B4 (de) * | 2005-08-08 | 2007-09-27 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Bildung einer Emulsion in einem fluidischen Mikrosystem |
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| DE102006036815B4 (de) * | 2006-08-07 | 2010-01-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Emulgiereinrichtung und Verfahren zur Bildung einer Emulsion |
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| WO2019204279A1 (en) * | 2018-04-16 | 2019-10-24 | Klaris Corporation | Methods and apparatus for forming 2-dimensional drop arrays |
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2016
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- 2016-03-15 US US15/070,108 patent/US10662470B2/en active Active
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| US20200263237A1 (en) | 2020-08-20 |
| EP3271058A1 (en) | 2018-01-24 |
| CN107427788B (zh) | 2021-03-19 |
| EP3271058A4 (en) | 2018-11-21 |
| JP2018511466A (ja) | 2018-04-26 |
| CN107427788A (zh) | 2017-12-01 |
| CA2979415A1 (en) | 2016-09-22 |
| US11098351B2 (en) | 2021-08-24 |
| EP3271058B1 (en) | 2021-10-06 |
| US20160271576A1 (en) | 2016-09-22 |
| WO2016149241A1 (en) | 2016-09-22 |
| KR102528348B1 (ko) | 2023-05-03 |
| KR20170129199A (ko) | 2017-11-24 |
| JP6726680B2 (ja) | 2020-07-22 |
| US10662470B2 (en) | 2020-05-26 |
| HK1246241A1 (zh) | 2018-09-07 |
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