HK1246241A1 - 用於多階梯通道乳化的儀器和方法 - Google Patents

用於多階梯通道乳化的儀器和方法

Info

Publication number
HK1246241A1
HK1246241A1 HK18105701.9A HK18105701A HK1246241A1 HK 1246241 A1 HK1246241 A1 HK 1246241A1 HK 18105701 A HK18105701 A HK 18105701A HK 1246241 A1 HK1246241 A1 HK 1246241A1
Authority
HK
Hong Kong
Prior art keywords
methods
step channel
emulsification
channel emulsification
channel
Prior art date
Application number
HK18105701.9A
Other languages
English (en)
Inventor
尼古拉斯．阿拉貝
阿諾爾德．埃斯特拉達
丹尼爾．菲納
羅斯．約翰遜
Original Assignee
盧米耐克斯公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 盧米耐克斯公司 filed Critical 盧米耐克斯公司
Publication of HK1246241A1 publication Critical patent/HK1246241A1/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/45—Mixing liquids with liquids; Emulsifying using flow mixing
    • B01F23/451—Mixing liquids with liquids; Emulsifying using flow mixing by injecting one liquid into another
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3017—Mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Colloid Chemistry (AREA)
  • Medicinal Preparation (AREA)
HK18105701.9A 2015-03-16 2018-05-03 用於多階梯通道乳化的儀器和方法 HK1246241A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562133621P 2015-03-16 2015-03-16
US201562269289P 2015-12-18 2015-12-18
PCT/US2016/022418 WO2016149241A1 (en) 2015-03-16 2016-03-15 Apparatus and methods for multi-step channel emulsification

Publications (1)

Publication Number Publication Date
HK1246241A1 true HK1246241A1 (zh) 2018-09-07

Family

ID=56919341

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105701.9A HK1246241A1 (zh) 2015-03-16 2018-05-03 用於多階梯通道乳化的儀器和方法

Country Status (8)

Country Link
US (2) US10662470B2 (zh)
EP (1) EP3271058B1 (zh)
JP (1) JP6726680B2 (zh)
KR (1) KR102528348B1 (zh)
CN (1) CN107427788B (zh)
CA (1) CA2979415C (zh)
HK (1) HK1246241A1 (zh)
WO (1) WO2016149241A1 (zh)

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JP7071056B2 (ja) * 2017-02-27 2022-05-18 シスメックス株式会社 液体送液方法および液体送液装置
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WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
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CN113747974A (zh) * 2019-02-28 2021-12-03 10X基因组学有限公司 用于提高液滴形成效率的装置、系统和方法
CN110075934B (zh) * 2019-03-25 2021-06-01 绍兴钠钇光电有限公司 一种3d打印微流控器件及其大通量制备单分散乳液的方法
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CN114929886A (zh) * 2019-08-20 2022-08-19 派特恩生物技术有限公司 用于筛选和后续处理取自非无菌场所的样本的方法
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US10953404B1 (en) 2020-04-24 2021-03-23 Pattern Bioscience, Inc. Apparatuses for contactless loading and imaging of microfluidic chips and related methods
US20220118447A1 (en) * 2020-10-19 2022-04-21 Pattern Bioscience, Inc. Microfluidic Chips Including a Gutter Having a Trough and a Ridge to Facilitate Loading Thereof and Related Methods
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Also Published As

Publication number Publication date
CN107427788A (zh) 2017-12-01
EP3271058A1 (en) 2018-01-24
US20160271576A1 (en) 2016-09-22
JP6726680B2 (ja) 2020-07-22
EP3271058A4 (en) 2018-11-21
KR102528348B1 (ko) 2023-05-03
CN107427788B (zh) 2021-03-19
KR20170129199A (ko) 2017-11-24
JP2018511466A (ja) 2018-04-26
CA2979415A1 (en) 2016-09-22
WO2016149241A1 (en) 2016-09-22
US11098351B2 (en) 2021-08-24
EP3271058B1 (en) 2021-10-06
US10662470B2 (en) 2020-05-26
CA2979415C (en) 2023-08-22
US20200263237A1 (en) 2020-08-20

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