JP2018509887A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018509887A5 JP2018509887A5 JP2017539548A JP2017539548A JP2018509887A5 JP 2018509887 A5 JP2018509887 A5 JP 2018509887A5 JP 2017539548 A JP2017539548 A JP 2017539548A JP 2017539548 A JP2017539548 A JP 2017539548A JP 2018509887 A5 JP2018509887 A5 JP 2018509887A5
- Authority
- JP
- Japan
- Prior art keywords
- hngal
- hngal mutein
- ang
- mutein
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15152826.2 | 2015-01-28 | ||
| EP15152826 | 2015-01-28 | ||
| PCT/EP2016/051657 WO2016120307A1 (en) | 2015-01-28 | 2016-01-27 | Novel proteins specific for angiogenesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018509887A JP2018509887A (ja) | 2018-04-12 |
| JP2018509887A5 true JP2018509887A5 (enExample) | 2019-03-07 |
| JP6839087B2 JP6839087B2 (ja) | 2021-03-03 |
Family
ID=52396588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017539548A Expired - Fee Related JP6839087B2 (ja) | 2015-01-28 | 2016-01-27 | 血管新生に特異的な新規のタンパク質 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10526382B2 (enExample) |
| EP (1) | EP3250586B1 (enExample) |
| JP (1) | JP6839087B2 (enExample) |
| KR (1) | KR20170105609A (enExample) |
| CN (1) | CN107207574A (enExample) |
| AU (1) | AU2016212087B2 (enExample) |
| BR (1) | BR112017015773A2 (enExample) |
| CA (1) | CA2973640A1 (enExample) |
| DK (1) | DK3250586T3 (enExample) |
| MX (1) | MX384075B (enExample) |
| RU (1) | RU2720688C2 (enExample) |
| SG (2) | SG11201705278QA (enExample) |
| WO (1) | WO2016120307A1 (enExample) |
| ZA (1) | ZA201704320B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3660510A3 (en) | 2009-12-07 | 2020-07-08 | Pieris Pharmaceuticals GmbH | Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target |
| CA2891557A1 (en) | 2013-03-26 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| SG10201912019WA (en) | 2014-05-22 | 2020-02-27 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| AU2016212087B2 (en) | 2015-01-28 | 2019-11-07 | Pieris Pharmaceuticals Gmbh | Novel proteins specific for angiogenesis |
| RU2736312C2 (ru) | 2015-05-04 | 2020-11-13 | ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ | Белки, специфичные в отношении cd137 |
| AU2016258977C1 (en) | 2015-05-04 | 2022-07-14 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptide |
| US10273275B2 (en) | 2015-05-18 | 2019-04-30 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) and methods of use thereof |
| AU2016262845B2 (en) | 2015-05-18 | 2020-07-23 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptide |
| EA035586B1 (ru) * | 2015-11-30 | 2020-07-10 | Пиерис Острелиа Пти Лтд. | Новые антиангиогенные слитые белки |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
| BR112018013407A2 (en) | 2015-12-30 | 2018-12-18 | Kodiak Sciences Inc. | antibodies and conjugates thereof |
| SG11202008242XA (en) | 2018-03-02 | 2020-09-29 | Kodiak Sciences Inc | Il-6 antibodies and fusion constructs and conjugates thereof |
| US11633399B2 (en) | 2018-12-25 | 2023-04-25 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with compositions comprising an EGFR inhibitor |
| KR20210146999A (ko) | 2019-03-29 | 2021-12-06 | 피어이스 파마슈티컬즈 게엠베하 | 리포칼린 뮤테인의 흡입 투여 |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| JP2023527908A (ja) | 2020-06-05 | 2023-06-30 | ピエリス ファーマシューティカルズ ゲーエムベーハー | ４－１ｂｂをターゲティングする多量体免疫調節物質 |
| EP4215204A1 (en) * | 2022-01-24 | 2023-07-26 | Universitat Pompeu Fabra | Human neutrophil gelatinase-associated lipocalin derived from recombinant bacteria and uses thereof |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3779221D1 (de) | 1986-08-19 | 1992-06-25 | Genentech Inc | Einrichtung und dispersion zum intrapulmonalen eingeben von polypeptidwuchsstoffen und -zytokinen. |
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| WO1995031479A1 (en) | 1994-05-18 | 1995-11-23 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
| DE4417598A1 (de) | 1994-05-19 | 1995-12-14 | Max Planck Gesellschaft | Verwendung des Tetracyclinpromotors zur stringent regulierten Produktion von rekombinanten Proteinen in prokaryontischen Zellen |
| AU5132096A (en) | 1995-01-30 | 1996-08-21 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| WO1998016873A1 (en) | 1996-10-14 | 1998-04-23 | Firm Forsat Ltd. | Method for preparing dispersions of chromogenic components |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| TR200003635T2 (tr) | 1998-06-08 | 2001-04-20 | F.Hoffmann-La Roche Ag | Peg-IFN-ALFA ve ribavirinin kronik hepatit C tedavisinde kullanılması. |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| DE19926068C1 (de) | 1999-06-08 | 2001-01-11 | Arne Skerra | Muteine des Bilin-Bindungsproteins |
| CA2440582A1 (en) | 2001-03-09 | 2002-10-03 | Dyax Corp. | Serum albumin binding moieties |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| EP1430136A1 (en) | 2001-09-27 | 2004-06-23 | Pieris ProteoLab AG | Muteins of apolipoprotein d |
| AU2003275958A1 (en) | 2003-08-25 | 2005-03-10 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| AU2003264100A1 (en) | 2003-08-25 | 2005-03-10 | Pieris Proteolab Ag | Muteins of a bilin-binding protein with affinity for a given target |
| JP2007284351A (ja) | 2004-07-27 | 2007-11-01 | Osaka Bioscience Institute | アミロイド蛋白質の凝集を抑制する物質とその作用 |
| EP2899277A1 (en) | 2004-11-26 | 2015-07-29 | Pieris AG | Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4) |
| JP2009509535A (ja) | 2005-09-27 | 2009-03-12 | アムニクス， インコーポレイテッド | タンパク様薬剤およびその使用 |
| NO347649B1 (no) | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| JP5848006B2 (ja) | 2007-10-19 | 2016-01-27 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | Ｎｇａｌの検出用イムノアッセイ及びキット |
| BRPI0905752B1 (pt) * | 2008-01-30 | 2021-11-23 | Pieris Ag | Muteína de lipocalina da lágrima humana (htlc), composição farmacêutica, método para a produção de uma muteína de lipocalina da lágrima humana e uso in vitro de uma muteína de lipocalina da lágrima humana |
| CA2729322C (en) * | 2008-06-24 | 2020-05-26 | Technische Universitaet Muenchen | Muteins of hngal and related proteins with affinity for a given target |
| US8133979B2 (en) * | 2008-12-16 | 2012-03-13 | Hoffmann-La Roche Inc. | Antibodies against human angiopoietin 2 |
| EP3660510A3 (en) | 2009-12-07 | 2020-07-08 | Pieris Pharmaceuticals GmbH | Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target |
| CA2808392C (en) * | 2010-08-16 | 2020-03-10 | Pieris Pharmaceuticals Gmbh | Binding proteins for hepcidin |
| EP2640740B1 (en) * | 2010-11-15 | 2017-03-15 | Pieris Pharmaceuticals GmbH | Muteins of human lipocalin 2 with affinity for glypican-3 (gpc3) |
| WO2013174783A1 (en) * | 2012-05-23 | 2013-11-28 | Pieris Ag | Lipocalin muteins with binding-affinity for glypican-3 (gpc-3) and use of lipocalin muteins for target-specific delivery to cells expressing gpc-3 |
| GB201223053D0 (en) | 2012-12-20 | 2013-02-06 | Medical Res Council | Receptor |
| CA2891557A1 (en) * | 2013-03-26 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| AU2016212087B2 (en) | 2015-01-28 | 2019-11-07 | Pieris Pharmaceuticals Gmbh | Novel proteins specific for angiogenesis |
| BR112017017530A2 (pt) | 2015-02-18 | 2018-04-17 | Sanofi | proteínas específicas para pioverdina e pioquelina |
| RU2736312C2 (ru) | 2015-05-04 | 2020-11-13 | ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ | Белки, специфичные в отношении cd137 |
| US10273275B2 (en) | 2015-05-18 | 2019-04-30 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) and methods of use thereof |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
-
2016
- 2016-01-27 AU AU2016212087A patent/AU2016212087B2/en not_active Ceased
- 2016-01-27 DK DK16703451.1T patent/DK3250586T3/da active
- 2016-01-27 SG SG11201705278QA patent/SG11201705278QA/en unknown
- 2016-01-27 BR BR112017015773-0A patent/BR112017015773A2/pt not_active Application Discontinuation
- 2016-01-27 US US15/546,609 patent/US10526382B2/en active Active
- 2016-01-27 CN CN201680007089.1A patent/CN107207574A/zh active Pending
- 2016-01-27 JP JP2017539548A patent/JP6839087B2/ja not_active Expired - Fee Related
- 2016-01-27 CA CA2973640A patent/CA2973640A1/en active Pending
- 2016-01-27 EP EP16703451.1A patent/EP3250586B1/en active Active
- 2016-01-27 SG SG10201906859PA patent/SG10201906859PA/en unknown
- 2016-01-27 KR KR1020177023448A patent/KR20170105609A/ko not_active Ceased
- 2016-01-27 RU RU2017128105A patent/RU2720688C2/ru active
- 2016-01-27 WO PCT/EP2016/051657 patent/WO2016120307A1/en not_active Ceased
- 2016-01-27 MX MX2017009767A patent/MX384075B/es unknown
-
2017
- 2017-06-26 ZA ZA2017/04320A patent/ZA201704320B/en unknown
-
2019
- 2019-11-13 US US16/682,499 patent/US11034738B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018509887A5 (enExample) | ||
| JP6779252B2 (ja) | ＩＬ−１βへの結合メンバー | |
| CN112646031B (zh) | 抗4-1bb纳米抗体及其用途 | |
| RU2017128105A (ru) | Новые белки, специфические в отношении ангиогенеза | |
| KR102408356B1 (ko) | 항―axl 항체 | |
| KR102453226B1 (ko) | 항―axl 항체 | |
| US20230340158A1 (en) | Anti-vegf-anti-pd-l1 bispecific antibody, pharmaceutical composition of same, and uses thereof | |
| KR101541478B1 (ko) | 항-vegf 항체 및 이를 포함하는 암 또는 신생혈관형성관련 질환의 예방, 진단 또는 치료용 약학 조성물 | |
| IL258419A (en) | A new polypeptide with affinity for pd-l1 | |
| KR101739489B1 (ko) | 인간 유래 항-인간 표피 생장인자 수용체 항체 및 그의 코딩 유전자와 용도 | |
| JP2018532372A5 (enExample) | ||
| KR20140130685A (ko) | Ｃｘ3ｃｒ1-결합 폴리펩타이드 | |
| JP2005528914A5 (enExample) | ||
| JP2019505565A5 (enExample) | ||
| JP7743406B2 (ja) | 抗ｂｃｍａ ｃａｒ抗体、コンジュゲートおよび使用方法 | |
| JP2023537958A (ja) | Ｂｃｍａと結合する単一可変ドメイン及び抗原結合分子 | |
| KR20240023095A (ko) | Vegf 및 ang2에 결합하는 이중특이적 결합 분자 및 이의 사용 | |
| CA3114295A1 (en) | Il-36 antibodies and uses thereof | |
| CA3208368A1 (en) | Vegfa-binding molecules | |
| EP2373335A1 (en) | Anti-ferroportin 1 monoclonal antibodies and uses thereof | |
| WO2016112497A1 (zh) | 人源抗人α干扰素抗体及其应用 | |
| KR20230045095A (ko) | Bcma와 결합하는 단일 가변 도메인 및 항원 결합 분자 | |
| WO2023221935A1 (zh) | 结合pd-l1和cldn18.2的抗体及其用途 | |
| WO2016059068A1 (en) | Vegfr-2 binding polypeptides | |
| WO2016059057A1 (en) | Vegfr-2 binding polypeptides |