JP2018509421A5 - - Google Patents
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- Publication number
- JP2018509421A5 JP2018509421A5 JP2017548117A JP2017548117A JP2018509421A5 JP 2018509421 A5 JP2018509421 A5 JP 2018509421A5 JP 2017548117 A JP2017548117 A JP 2017548117A JP 2017548117 A JP2017548117 A JP 2017548117A JP 2018509421 A5 JP2018509421 A5 JP 2018509421A5
- Authority
- JP
- Japan
- Prior art keywords
- sulfonate
- crystal
- organic solvent
- nintedanib
- diethane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510112909.0A CN106008308A (zh) | 2015-03-13 | 2015-03-13 | 尼达尼布乙磺酸盐结晶 |
| CN201510112909.0 | 2015-03-13 | ||
| PCT/CN2016/076110 WO2016146020A1 (zh) | 2015-03-13 | 2016-03-11 | 尼达尼布二乙磺酸盐晶体及其制备方法和用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018509421A JP2018509421A (ja) | 2018-04-05 |
| JP2018509421A5 true JP2018509421A5 (enExample) | 2019-04-18 |
Family
ID=56918371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548117A Pending JP2018509421A (ja) | 2015-03-13 | 2016-03-11 | ニンテダニブジエタンスルホン酸塩結晶並びにその製造方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10292965B2 (enExample) |
| EP (1) | EP3269710B1 (enExample) |
| JP (1) | JP2018509421A (enExample) |
| CN (2) | CN106008308A (enExample) |
| RU (1) | RU2708683C2 (enExample) |
| WO (1) | WO2016146020A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7306697B2 (ja) * | 2017-03-14 | 2023-07-11 | オールジェネシス バイオセラピューティクス インコーポレイテッド | ３－ｚ－［１－（４－（ｎ－（（４－メチル－ピペラジン－１－イル）－メチルカルボニル）－ｎ－メチル－アミノ）－フェニルアミノ）－１－フェニル－メチレン］－６－メトキシカルボニル－２－インドリノンの結晶形 |
| JP7382317B2 (ja) | 2017-11-17 | 2023-11-16 | フェルミオン オサケ ユキチュア | ニンテダニブを製造するための中間体として公知の２－インドリノン誘導体の合成 |
| CN113024439A (zh) * | 2021-03-28 | 2021-06-25 | 郑州大学 | 尼达尼布乙磺酸盐新晶型ⅰ的制备 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10233500A1 (de) * | 2002-07-24 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel |
| EP1870400A1 (en) * | 2006-06-08 | 2007-12-26 | Boehringer Ingelheim Pharma GmbH & Co. KG | Salts and crystalline salt forms of an 2-indolinone derivative |
| TR201802086T4 (tr) * | 2007-12-03 | 2018-03-21 | Boehringer Ingelheim Int | Bir indolinon türevinin imalatı için proses. |
| WO2012068441A2 (en) * | 2010-11-19 | 2012-05-24 | Ratiopharm Gmbh | Intedanib salts and solid state forms thereof |
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2015
- 2015-03-13 CN CN201510112909.0A patent/CN106008308A/zh not_active Withdrawn
-
2016
- 2016-03-11 RU RU2017136104A patent/RU2708683C2/ru not_active IP Right Cessation
- 2016-03-11 US US15/558,050 patent/US10292965B2/en not_active Expired - Fee Related
- 2016-03-11 JP JP2017548117A patent/JP2018509421A/ja active Pending
- 2016-03-11 CN CN201680014054.0A patent/CN107428686A/zh active Pending
- 2016-03-11 WO PCT/CN2016/076110 patent/WO2016146020A1/zh not_active Ceased
- 2016-03-11 EP EP16764201.6A patent/EP3269710B1/en active Active