JP2018508526A5 - - Google Patents
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- JP2018508526A5 JP2018508526A5 JP2017546181A JP2017546181A JP2018508526A5 JP 2018508526 A5 JP2018508526 A5 JP 2018508526A5 JP 2017546181 A JP2017546181 A JP 2017546181A JP 2017546181 A JP2017546181 A JP 2017546181A JP 2018508526 A5 JP2018508526 A5 JP 2018508526A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- therapeutic agent
- subject
- psc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562129698P | 2015-03-06 | 2015-03-06 | |
| US62/129,698 | 2015-03-06 | ||
| PCT/US2016/020819 WO2016144720A1 (en) | 2015-03-06 | 2016-03-04 | Method of treating primary sclerosing cholangitis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018508526A JP2018508526A (ja) | 2018-03-29 |
| JP2018508526A5 true JP2018508526A5 (https=) | 2019-04-11 |
| JP6942053B2 JP6942053B2 (ja) | 2021-09-29 |
Family
ID=55699788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546181A Active JP6942053B2 (ja) | 2015-03-06 | 2016-03-04 | 原発性硬化性胆管炎を治療する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20180051086A1 (https=) |
| EP (2) | EP4257200A3 (https=) |
| JP (1) | JP6942053B2 (https=) |
| KR (1) | KR20170120622A (https=) |
| AU (1) | AU2016229193A1 (https=) |
| BR (1) | BR112017019071A2 (https=) |
| CA (1) | CA2978725A1 (https=) |
| EA (1) | EA201791970A1 (https=) |
| MA (1) | MA41636A (https=) |
| MX (1) | MX2017011272A (https=) |
| WO (1) | WO2016144720A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA41636A (fr) | 2015-03-06 | 2018-01-09 | Millennium Pharm Inc | Méthode de traitement de la cholangite sclérosante primitive |
| IL261750B2 (en) * | 2016-03-14 | 2024-07-01 | Millennium Pharm Inc | Method of preventing graft versus host disease |
| BR112018068625A2 (pt) * | 2016-03-14 | 2019-07-30 | Millennium Pharm Inc | métodos de tratamento ou prevenção de doença de enxerto contra hospedeiro |
| CN109414502A (zh) | 2016-06-12 | 2019-03-01 | 千禧制药公司 | 治疗炎症性肠病的方法 |
| EP3956358A4 (en) * | 2019-04-17 | 2023-01-25 | Millennium Pharmaceuticals, Inc. | COMBINATION THERAPY WITH ALPHA4BETA7 INHIBITOR AND IL-23 INHIBITOR |
| US20220267449A1 (en) * | 2019-06-10 | 2022-08-25 | Takeda Pharmaceutical Company Limited | METHODS OF PRODUCING AN ANTI-a4B7 ANTIBODY |
| WO2022075756A1 (ko) | 2020-10-08 | 2022-04-14 | 주식회사 큐롬바이오사이언스 | 베타-라파촌을 유효성분으로 포함하는 담즙 정체성 간질환 예방 또는 치료용 약학 조성물 |
| WO2024249568A1 (en) | 2023-05-30 | 2024-12-05 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
| CN121889424A (zh) | 2023-08-14 | 2026-04-17 | 派拉冈医疗公司 | α4β7整联蛋白结合蛋白及使用方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| JP3095168B2 (ja) | 1988-02-05 | 2000-10-03 | エル． モリソン，シェリー | ドメイン‐変性不変部を有する抗体 |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| EP0808367B1 (en) | 1995-02-10 | 2007-07-11 | Millennium Pharmaceuticals, Inc. | Mucosal vascular addressins and uses thereof |
| US7147851B1 (en) | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| US7090845B2 (en) | 1998-05-13 | 2006-08-15 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
| DE69940503D1 (de) * | 1998-05-13 | 2009-04-16 | Genentech Inc | Diagnose und behandlung von hepatischen krankheiten |
| EP2399903A1 (en) | 2002-05-24 | 2011-12-28 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| US6939885B2 (en) | 2002-11-18 | 2005-09-06 | Chemocentryx | Aryl sulfonamides |
| RS52213B (sr) | 2004-09-03 | 2012-10-31 | Genentech, Inc. | Humanizovani anti-beta7 antagonisti i njihove primene |
| JP2009515552A (ja) * | 2005-11-17 | 2009-04-16 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | α４β７インテグリン反応性ヒト化免疫グロブリン |
| CN103382222B (zh) | 2009-03-20 | 2016-12-28 | 安姆根有限公司 | α-4-β-7异二聚体特异性拮抗剂抗体 |
| UA116189C2 (uk) | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
| DK3311834T3 (da) | 2011-05-02 | 2026-04-20 | Millennium Pharmaceuticals Inc | Formulering til anti-alfa4beta7-antistof |
| MA41636A (fr) | 2015-03-06 | 2018-01-09 | Millennium Pharm Inc | Méthode de traitement de la cholangite sclérosante primitive |
-
2016
- 2016-03-03 MA MA041636A patent/MA41636A/fr unknown
- 2016-03-04 WO PCT/US2016/020819 patent/WO2016144720A1/en not_active Ceased
- 2016-03-04 CA CA2978725A patent/CA2978725A1/en not_active Abandoned
- 2016-03-04 EP EP22213419.9A patent/EP4257200A3/en active Pending
- 2016-03-04 AU AU2016229193A patent/AU2016229193A1/en not_active Abandoned
- 2016-03-04 KR KR1020177025412A patent/KR20170120622A/ko not_active Withdrawn
- 2016-03-04 US US15/556,186 patent/US20180051086A1/en not_active Abandoned
- 2016-03-04 BR BR112017019071A patent/BR112017019071A2/pt not_active Application Discontinuation
- 2016-03-04 EA EA201791970A patent/EA201791970A1/ru unknown
- 2016-03-04 JP JP2017546181A patent/JP6942053B2/ja active Active
- 2016-03-04 EP EP16715375.8A patent/EP3265492A1/en not_active Withdrawn
- 2016-03-04 MX MX2017011272A patent/MX2017011272A/es unknown
-
2021
- 2021-02-24 US US17/184,116 patent/US12391760B2/en active Active
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