JP2018507255A5 - - Google Patents
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- Publication number
- JP2018507255A5 JP2018507255A5 JP2017558782A JP2017558782A JP2018507255A5 JP 2018507255 A5 JP2018507255 A5 JP 2018507255A5 JP 2017558782 A JP2017558782 A JP 2017558782A JP 2017558782 A JP2017558782 A JP 2017558782A JP 2018507255 A5 JP2018507255 A5 JP 2018507255A5
- Authority
- JP
- Japan
- Prior art keywords
- imidazo
- amino
- pyridin
- chloro
- phenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15153394 | 2015-02-02 | ||
| EP15153394.0 | 2015-02-02 | ||
| PCT/EP2016/052091 WO2016124553A1 (en) | 2015-02-02 | 2016-02-01 | 2-phenyl-3h-imidazo[4,5-b]pyridine derivates useful as inhibitors of mammalian tyrosine kinase ror1 activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507255A JP2018507255A (ja) | 2018-03-15 |
| JP2018507255A5 true JP2018507255A5 (https=) | 2019-02-28 |
| JP6629884B2 JP6629884B2 (ja) | 2020-01-15 |
Family
ID=52449976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558782A Expired - Fee Related JP6629884B2 (ja) | 2015-02-02 | 2016-02-01 | 哺乳動物のチロシンキナーゼｒｏｒ１活性の阻害剤として有用な２−フェニル−３ｈ−イミダゾ［４，５−ｂ］ピリジン誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10550113B2 (https=) |
| EP (1) | EP3253754B1 (https=) |
| JP (1) | JP6629884B2 (https=) |
| KR (1) | KR102493943B1 (https=) |
| CN (1) | CN107567445B (https=) |
| AU (1) | AU2016214492B2 (https=) |
| BR (1) | BR112017016428B1 (https=) |
| CA (1) | CA2973773C (https=) |
| ES (1) | ES2875737T3 (https=) |
| IL (1) | IL253380B (https=) |
| MX (1) | MX374552B (https=) |
| WO (1) | WO2016124553A1 (https=) |
| ZA (1) | ZA201705933B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11660303B2 (en) | 2016-07-11 | 2023-05-30 | Kancera Ab | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity |
| EP3481824B1 (en) * | 2016-07-11 | 2021-10-20 | Kancera AB | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ror1 activity |
| GB201710835D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Antibodies |
| GB201710836D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Car T-Cells |
| GB201710838D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | Bispecific antibodies |
| JP7378267B2 (ja) | 2018-11-12 | 2023-11-13 | 東ソー株式会社 | コバルト錯体、その製造方法、及びコバルト含有薄膜の製造方法 |
| JP7641902B2 (ja) | 2019-01-29 | 2025-03-07 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ カリフォルニア | 緑内障の新規治療法 |
| CN112574176B (zh) * | 2019-09-27 | 2024-03-15 | 隆泰申医药科技(南京)有限公司 | 一种杂芳基类化合物及其应用 |
| CN117049977A (zh) * | 2023-08-16 | 2023-11-14 | 四川伊诺达博医药科技有限公司 | 一种n-乙基-2-(4-甲酰基苯基)乙酰胺的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1460067A4 (en) | 2001-11-26 | 2005-12-07 | Takeda Pharmaceutical | BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE |
| SE0202464D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Use of compounds |
| SE0202462D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel use |
| CN101830899A (zh) | 2004-12-23 | 2010-09-15 | 霍夫曼-拉罗奇有限公司 | 杂环氨基甲酸酯衍生物,它们的制备及作为药剂的应用 |
| JP2008525355A (ja) | 2004-12-23 | 2008-07-17 | エフ．ホフマン−ラ ロシュ アーゲー | ベンズアミド誘導体、これらの製造及び医薬剤としての使用。 |
| AU2006209117B2 (en) | 2005-01-28 | 2009-12-10 | Daewoong Pharmaceutical Co., Ltd. | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
| EP1891069A1 (en) | 2005-05-24 | 2008-02-27 | AstraZeneca AB | 2-phenyl substituted imidazol [4,5b]pyridine/ pyrazine and purine derivatives as glucokinase modulators |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| US8088761B2 (en) | 2005-12-22 | 2012-01-03 | Cancer Research Technology Limited | Enzyme inhibitors |
| WO2007083978A1 (en) | 2006-01-23 | 2007-07-26 | Crystalgenomics, Inc. | Imidazopyridine derivatives inhibiting protein kinase activity, method for the preparation thereof and pharmaceutical composition containing same |
| WO2008121063A1 (en) | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | New imidazo[ 4,5-b]pyridine-7-carboxamides 704 |
| WO2008121064A1 (en) | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705 |
| WO2009001021A1 (en) | 2007-06-26 | 2008-12-31 | Chroma Therapeutics Ltd. | Imidazopyridine derivatives useful as enzyme inhibitors for the treatment of cell proliferative and autoimmune diseases |
| CA2716947A1 (en) | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | Imidazo [4,5-b] pyridine derivatives used as raf inhibitors |
| US20120295915A1 (en) | 2009-11-24 | 2012-11-22 | Chaudhari Amita M | Azabenzimidazoles as fatty acid synthase inhibitors |
| US9150647B2 (en) | 2009-12-18 | 2015-10-06 | Kancera Ab | Biological inhibitors of ROR1 capable of inducing cell death |
| ES2567552T3 (es) * | 2012-01-30 | 2016-04-25 | Cephalon, Inc. | Imidazo [4,5-b] derivados de piridina como los moduladores ALK y JAK para el tratamiento de trastornos proliferativos |
-
2016
- 2016-02-01 CN CN201680008251.1A patent/CN107567445B/zh not_active Expired - Fee Related
- 2016-02-01 JP JP2017558782A patent/JP6629884B2/ja not_active Expired - Fee Related
- 2016-02-01 CA CA2973773A patent/CA2973773C/en active Active
- 2016-02-01 WO PCT/EP2016/052091 patent/WO2016124553A1/en not_active Ceased
- 2016-02-01 AU AU2016214492A patent/AU2016214492B2/en not_active Ceased
- 2016-02-01 US US15/545,523 patent/US10550113B2/en active Active
- 2016-02-01 BR BR112017016428-0A patent/BR112017016428B1/pt not_active IP Right Cessation
- 2016-02-01 EP EP16702147.6A patent/EP3253754B1/en active Active
- 2016-02-01 ES ES16702147T patent/ES2875737T3/es active Active
- 2016-02-01 KR KR1020177024661A patent/KR102493943B1/ko active Active
- 2016-02-01 MX MX2017009600A patent/MX374552B/es active IP Right Grant
-
2017
- 2017-07-10 IL IL253380A patent/IL253380B/en unknown
- 2017-08-31 ZA ZA2017/05933A patent/ZA201705933B/en unknown
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