JP2018507245A5 - - Google Patents
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- Publication number
- JP2018507245A5 JP2018507245A5 JP2017546767A JP2017546767A JP2018507245A5 JP 2018507245 A5 JP2018507245 A5 JP 2018507245A5 JP 2017546767 A JP2017546767 A JP 2017546767A JP 2017546767 A JP2017546767 A JP 2017546767A JP 2018507245 A5 JP2018507245 A5 JP 2018507245A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- tumor
- brain tumor
- brain
- purinaburin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000003174 Brain Neoplasms Diseases 0.000 claims 12
- 206010003571 Astrocytoma Diseases 0.000 claims 5
- 208000005017 glioblastoma Diseases 0.000 claims 4
- 206010014967 Ependymoma Diseases 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000010133 Oligodendroglioma Diseases 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 230000001394 metastastic effect Effects 0.000 claims 3
- 206010061289 metastatic neoplasm Diseases 0.000 claims 3
- 206010002224 anaplastic astrocytoma Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 206010027191 meningioma Diseases 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010007953 Central nervous system lymphoma Diseases 0.000 claims 1
- 208000004139 Choroid Plexus Neoplasms Diseases 0.000 claims 1
- 208000004378 Choroid plexus papilloma Diseases 0.000 claims 1
- 208000037156 Choroid plexus tumor Diseases 0.000 claims 1
- 208000032612 Glial tumor Diseases 0.000 claims 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 claims 1
- 206010018338 Glioma Diseases 0.000 claims 1
- 208000000172 Medulloblastoma Diseases 0.000 claims 1
- 206010029260 Neuroblastoma Diseases 0.000 claims 1
- 208000008846 Neurocytoma Diseases 0.000 claims 1
- 208000005890 Neuroma Diseases 0.000 claims 1
- 208000037064 Papilloma of choroid plexus Diseases 0.000 claims 1
- 206010050487 Pinealoblastoma Diseases 0.000 claims 1
- 208000007641 Pinealoma Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical group O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 201000000053 blastoma Diseases 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 230000002490 cerebral effect Effects 0.000 claims 1
- 208000015632 childhood ependymoma Diseases 0.000 claims 1
- 201000007369 choroid plexus cancer Diseases 0.000 claims 1
- 230000001886 ciliary effect Effects 0.000 claims 1
- 201000008184 embryoma Diseases 0.000 claims 1
- 208000010932 epithelial neoplasm Diseases 0.000 claims 1
- 201000008361 ganglioneuroma Diseases 0.000 claims 1
- 201000011610 giant cell glioblastoma Diseases 0.000 claims 1
- 208000002409 gliosarcoma Diseases 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 201000000050 myeloid neoplasm Diseases 0.000 claims 1
- 210000003757 neuroblast Anatomy 0.000 claims 1
- 208000027831 neuroepithelial neoplasm Diseases 0.000 claims 1
- 210000001328 optic nerve Anatomy 0.000 claims 1
- 201000000389 pediatric ependymoma Diseases 0.000 claims 1
- 201000003113 pineoblastoma Diseases 0.000 claims 1
- 208000016800 primary central nervous system lymphoma Diseases 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 210000001525 retina Anatomy 0.000 claims 1
- 210000004500 stellate cell Anatomy 0.000 claims 1
- 229960004964 temozolomide Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562129623P | 2015-03-06 | 2015-03-06 | |
| US62/129,623 | 2015-03-06 | ||
| US201562249807P | 2015-11-02 | 2015-11-02 | |
| US62/249,807 | 2015-11-02 | ||
| PCT/US2016/020396 WO2016144636A1 (en) | 2015-03-06 | 2016-03-02 | Method of treating a brain tumor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021026411A Division JP7264331B2 (ja) | 2015-03-06 | 2021-02-22 | 脳腫瘍の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507245A JP2018507245A (ja) | 2018-03-15 |
| JP2018507245A5 true JP2018507245A5 (enExample) | 2019-04-11 |
| JP6904570B2 JP6904570B2 (ja) | 2021-07-21 |
Family
ID=56880412
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546767A Active JP6904570B2 (ja) | 2015-03-06 | 2016-03-02 | 脳腫瘍の治療方法 |
| JP2021026411A Active JP7264331B2 (ja) | 2015-03-06 | 2021-02-22 | 脳腫瘍の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021026411A Active JP7264331B2 (ja) | 2015-03-06 | 2021-02-22 | 脳腫瘍の治療方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10076518B2 (enExample) |
| EP (1) | EP3265091A4 (enExample) |
| JP (2) | JP6904570B2 (enExample) |
| KR (1) | KR102623404B1 (enExample) |
| CN (1) | CN107530340B (enExample) |
| AU (2) | AU2016229295B2 (enExample) |
| BR (1) | BR112017018964A2 (enExample) |
| CL (1) | CL2017002242A1 (enExample) |
| HK (1) | HK1249051A1 (enExample) |
| IL (1) | IL254262A0 (enExample) |
| MX (1) | MX385914B (enExample) |
| MY (1) | MY194341A (enExample) |
| RU (1) | RU2728796C2 (enExample) |
| SG (1) | SG11201707128TA (enExample) |
| WO (1) | WO2016144636A1 (enExample) |
| ZA (1) | ZA201706035B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102626155B1 (ko) * | 2015-03-06 | 2024-01-17 | 비욘드스프링 파마수티컬스, 인코포레이티드. | Ras 돌연변이와 관련된 암의 치료 방법 |
| JP6904570B2 (ja) | 2015-03-06 | 2021-07-21 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | 脳腫瘍の治療方法 |
| AU2016291708B2 (en) | 2015-07-13 | 2020-12-24 | Beyondspring Pharmaceuticals, Inc | Plinabulin compositions |
| EP3413885A4 (en) | 2016-02-08 | 2019-09-18 | Beyondspring Pharmaceuticals, Inc. | COMPOSITIONS WITH TUCARESOL OR ITS ANALOG |
| SG11201810872UA (en) | 2016-06-06 | 2019-01-30 | Beyondspring Pharmaceuticals Inc | Composition and method for reducing neutropenia |
| US11633393B2 (en) | 2017-01-06 | 2023-04-25 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| US11400086B2 (en) * | 2017-02-01 | 2022-08-02 | Beyondspring Pharmaceuticals, Inc. | Method of reducing chemotherapy-induced neutropenia |
| JP7350015B2 (ja) * | 2018-01-24 | 2023-09-25 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | プリナブリンの投与による血小板減少症を軽減するための組成物および方法 |
| WO2020018700A1 (en) * | 2018-07-18 | 2020-01-23 | Manzanita Pharmaceuticals, Inc. | Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof |
| WO2021150109A1 (en) * | 2020-01-22 | 2021-07-29 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Abt-751 and ionizing radiation |
| BR112022020595A2 (pt) * | 2020-04-10 | 2023-01-17 | Lantern Pharma Inc | Métodos hidroxiureametil-acilfulveno para tratamento de câncer do cérebro ou câncer do snc. |
| EP4274662A4 (en) * | 2021-01-08 | 2024-11-27 | Lantern Pharma Inc. | Treatment of brain metastases and cns metastases using illudins or hydroxylureamethyl acylfulvene |
| WO2022216908A1 (en) * | 2021-04-09 | 2022-10-13 | Beyondspring Pharmaceuticals, Inc. | Therapeutic compositions and methods for treating tumors |
| CN117860672A (zh) | 2022-10-11 | 2024-04-12 | 大连万春布林医药有限公司 | 一种普那布林胶束组合物及其制备方法 |
| CN120682197A (zh) * | 2024-03-19 | 2025-09-23 | 大连万春布林医药有限公司 | 普那布林的盐晶型 |
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| CA2926771C (en) | 2013-10-11 | 2022-07-05 | Beyondspring Pharmaceuticals, Inc. | Cancer treatment with combination of plinabulin and taxane |
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| KR102626155B1 (ko) | 2015-03-06 | 2024-01-17 | 비욘드스프링 파마수티컬스, 인코포레이티드. | Ras 돌연변이와 관련된 암의 치료 방법 |
| JP6904570B2 (ja) | 2015-03-06 | 2021-07-21 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | 脳腫瘍の治療方法 |
| AU2016291708B2 (en) | 2015-07-13 | 2020-12-24 | Beyondspring Pharmaceuticals, Inc | Plinabulin compositions |
| EP3413885A4 (en) | 2016-02-08 | 2019-09-18 | Beyondspring Pharmaceuticals, Inc. | COMPOSITIONS WITH TUCARESOL OR ITS ANALOG |
| SG11201810872UA (en) | 2016-06-06 | 2019-01-30 | Beyondspring Pharmaceuticals Inc | Composition and method for reducing neutropenia |
| US11633393B2 (en) | 2017-01-06 | 2023-04-25 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| US11400086B2 (en) | 2017-02-01 | 2022-08-02 | Beyondspring Pharmaceuticals, Inc. | Method of reducing chemotherapy-induced neutropenia |
| CA3056077A1 (en) | 2017-03-13 | 2018-09-20 | Beyondspring Pharmaceuticals, Inc. | Compositions of plinabulin and use thereof |
-
2016
- 2016-03-02 JP JP2017546767A patent/JP6904570B2/ja active Active
- 2016-03-02 SG SG11201707128TA patent/SG11201707128TA/en unknown
- 2016-03-02 BR BR112017018964A patent/BR112017018964A2/pt not_active Application Discontinuation
- 2016-03-02 MY MYPI2017703256A patent/MY194341A/en unknown
- 2016-03-02 US US15/555,956 patent/US10076518B2/en active Active
- 2016-03-02 KR KR1020177026283A patent/KR102623404B1/ko active Active
- 2016-03-02 AU AU2016229295A patent/AU2016229295B2/en active Active
- 2016-03-02 WO PCT/US2016/020396 patent/WO2016144636A1/en not_active Ceased
- 2016-03-02 CN CN201680020652.9A patent/CN107530340B/zh active Active
- 2016-03-02 EP EP16762150.7A patent/EP3265091A4/en active Pending
- 2016-03-02 MX MX2017011375A patent/MX385914B/es unknown
- 2016-03-02 HK HK18108933.3A patent/HK1249051A1/zh unknown
- 2016-03-02 RU RU2017131448A patent/RU2728796C2/ru active
-
2017
- 2017-08-31 IL IL254262A patent/IL254262A0/en unknown
- 2017-09-04 CL CL2017002242A patent/CL2017002242A1/es unknown
- 2017-09-05 ZA ZA2017/06035A patent/ZA201706035B/en unknown
-
2018
- 2018-09-05 US US16/122,482 patent/US10357491B2/en active Active
-
2021
- 2021-02-22 JP JP2021026411A patent/JP7264331B2/ja active Active
- 2021-10-19 AU AU2021254549A patent/AU2021254549B2/en active Active
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