JP2018501218A5 - - Google Patents

Download PDF

Info

Publication number
JP2018501218A5
JP2018501218A5 JP2017529395A JP2017529395A JP2018501218A5 JP 2018501218 A5 JP2018501218 A5 JP 2018501218A5 JP 2017529395 A JP2017529395 A JP 2017529395A JP 2017529395 A JP2017529395 A JP 2017529395A JP 2018501218 A5 JP2018501218 A5 JP 2018501218A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
antibody
composition according
effective amount
configuration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017529395A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018501218A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/063194 external-priority patent/WO2016089873A1/en
Publication of JP2018501218A publication Critical patent/JP2018501218A/ja
Publication of JP2018501218A5 publication Critical patent/JP2018501218A5/ja
Pending legal-status Critical Current

Links

JP2017529395A 2014-12-02 2015-12-01 併用療法 Pending JP2018501218A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462086533P 2014-12-02 2014-12-02
US62/086,533 2014-12-02
PCT/US2015/063194 WO2016089873A1 (en) 2014-12-02 2015-12-01 Combination therapies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021001228A Division JP2021063114A (ja) 2014-12-02 2021-01-07 併用療法

Publications (2)

Publication Number Publication Date
JP2018501218A JP2018501218A (ja) 2018-01-18
JP2018501218A5 true JP2018501218A5 (OSRAM) 2019-06-06

Family

ID=56092328

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017529395A Pending JP2018501218A (ja) 2014-12-02 2015-12-01 併用療法
JP2021001228A Pending JP2021063114A (ja) 2014-12-02 2021-01-07 併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021001228A Pending JP2021063114A (ja) 2014-12-02 2021-01-07 併用療法

Country Status (12)

Country Link
US (1) US20170326234A1 (OSRAM)
EP (1) EP3226856A4 (OSRAM)
JP (2) JP2018501218A (OSRAM)
KR (1) KR20170101925A (OSRAM)
CN (1) CN107205979A (OSRAM)
AU (1) AU2015355137A1 (OSRAM)
BR (1) BR112017011536A2 (OSRAM)
CA (1) CA2968680A1 (OSRAM)
IL (1) IL252442A0 (OSRAM)
MX (1) MX2017007321A (OSRAM)
SG (1) SG11201703925VA (OSRAM)
WO (1) WO2016089873A1 (OSRAM)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8217149B2 (en) 2008-12-09 2012-07-10 Genentech, Inc. Anti-PD-L1 antibodies, compositions and articles of manufacture
AU2012253571A1 (en) 2011-05-09 2014-01-09 Mayo Foundation For Medical Education And Research Cancer treatments
US10413606B2 (en) 2012-10-01 2019-09-17 Mayo Foundation For Medical Education And Research Methods for treating cancer with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies
CR20160319A (es) 2013-12-12 2016-11-08 Jiangsu Hengrui Medicine Co Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
CN113318239B (zh) 2014-06-13 2025-05-30 梅约医药教育及研究基金会 治疗淋巴瘤
KR20210125603A (ko) 2014-06-16 2021-10-18 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 골수종의 치료
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
SG10201810615VA (en) 2015-02-26 2019-01-30 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for the treatment of cancer
GB201509338D0 (en) 2015-05-29 2015-07-15 Bergenbio As Combination therapy
US10869924B2 (en) 2015-06-16 2020-12-22 Merck Patent Gmbh PD-L1 antagonist combination treatments
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體-抗體組合物及其製造及使用方法
TW201713360A (en) 2015-10-06 2017-04-16 Mayo Foundation Methods of treating cancer using compositions of antibodies and carrier proteins
US11571469B2 (en) 2016-01-07 2023-02-07 Mayo Foundation For Medical Education And Research Methods of treating cancer with interferon wherein the cancer cells are HLA negative or have reduced HLA expression
WO2017151517A1 (en) 2016-02-29 2017-09-08 Foundation Medicine, Inc. Methods of treating cancer
KR102500659B1 (ko) 2016-02-29 2023-02-16 제넨테크, 인크. 암에 대한 치료 및 진단 방법
AU2017238119A1 (en) 2016-03-21 2018-10-11 Mayo Foundation For Medical Education And Research Methods for reducing toxicity of a chemotherapeutic drug
US11878061B2 (en) 2016-03-21 2024-01-23 Mayo Foundation For Medical Education And Research Methods for improving the therapeutic index for a chemotherapeutic drug
US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
EP3481422A1 (en) * 2016-07-06 2019-05-15 Pierre Fabre Medicament Vinflunine and pd1 and/or pdl1 inhibitor as pharmaceutical combination
JP2019526579A (ja) 2016-09-01 2019-09-19 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチMayo Foundation For Medical Education And Research T細胞癌を標的とする為の方法及び組成物
RU2019109211A (ru) * 2016-09-01 2020-10-01 Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч Композиции, содержащие носитель-pd-l1-связывающий агент для лечения рака
EP3510048A1 (en) * 2016-09-06 2019-07-17 Mayo Foundation for Medical Education and Research Methods of treating pd-l1 expressing cancer
WO2018048958A1 (en) 2016-09-06 2018-03-15 Mayo Foundation For Medical Education And Research Paclitaxel-albumin-binding agent compositions and methods for using and making the same
US11590098B2 (en) 2016-09-06 2023-02-28 Mayo Foundation For Medical Education And Research Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins
MX2019003934A (es) 2016-10-06 2019-07-10 Genentech Inc Métodos terapéuticos y de diagnóstico para el cáncer.
IL265762B2 (en) 2016-10-06 2024-04-01 Merck Patent Gmbh Dosing regimen of avelumab for the treatment of cancer
EP3571231A4 (en) 2017-01-20 2020-12-02 Tayu Huaxia Biotech Medical Group Co., Ltd. ANTI-PD-1 ANTIBODIES AND THEIR USES
MX2019009772A (es) * 2017-02-21 2019-12-02 Regeneron Pharma Anticuerpos anti-pd-1 para el tratamiento del cancer de pulmon.
JP7082110B2 (ja) 2017-03-29 2022-06-07 テルモ株式会社 アジュバント組成物およびこれを含むワクチン組成物並びに薬剤キット
IL271888B2 (en) * 2017-07-21 2024-09-01 Genentech Inc Therapeutic and diagnostic methods for cancer
BR112020005814A2 (pt) * 2017-10-03 2020-09-24 Crititech, Inc. administração local de partículas antineoplásicas em combinação com administração sistêmica de agentes imunoterapêuticos para o tratamento de câncer
CA3077664A1 (en) 2017-11-06 2019-05-09 Genentech, Inc. Diagnostic and therapeutic methods for cancer
WO2019108951A1 (en) * 2017-12-01 2019-06-06 Dana-Farber Cancer Institute, Inc. Compositions and methods for inhibiting dhhc-type palmitoyltransferases for cancer treatment
EP3768713A2 (en) 2018-03-22 2021-01-27 Keires AG Antagonistic pd-1, pd-l1 and lag-3 binding proteins
WO2019228514A1 (en) 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and uses thereof for treating disease or condition
WO2019227490A1 (en) 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and methods for imaging
AU2019288728A1 (en) 2018-06-23 2021-01-14 Genentech, Inc. Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
TW202011991A (zh) 2018-07-18 2020-04-01 美商建南德克公司 用pd-1軸結合拮抗劑、抗代謝劑及鉑劑治療肺癌之方法
WO2020015722A1 (en) * 2018-07-19 2020-01-23 Tayu Huaxia Biotech Medical Group Co., Ltd. Anti-pd-1 antibodies, dosages and uses thereof
TW202024023A (zh) 2018-09-03 2020-07-01 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法
JP2022518399A (ja) 2019-01-14 2022-03-15 ジェネンテック, インコーポレイテッド Pd-1軸結合アンタゴニスト及びrnaワクチンを用いてがんを処置する方法
CN113795511B (zh) 2019-01-23 2024-07-23 大有华夏生物医药集团有限公司 抗pd-l1双抗体及其用途
BR112021020867A2 (pt) 2019-04-19 2022-01-04 Genentech Inc Anticorpos, ácido nucleico, vetor, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, usos do anticorpo, método de tratamento de um indivíduo com câncer e método para reduzir a depuração
WO2021097110A1 (en) 2019-11-13 2021-05-20 Genentech, Inc. Therapeutic compounds and methods of use
BR112022015077A2 (pt) 2020-01-31 2022-10-04 Genentech Inc Métodos para induzir células t cd8+ específicas de neoepítopos em um indivíduo com um tumor e para induzir o tráfico de células t cd8+, vacinas de rna, vacina de rna para uso e antagonistas de ligação
US11787775B2 (en) 2020-07-24 2023-10-17 Genentech, Inc. Therapeutic compounds and methods of use
AR123855A1 (es) 2020-10-20 2023-01-18 Genentech Inc Anticuerpos anti-mertk conjugados con peg y métodos de uso
WO2022093981A1 (en) 2020-10-28 2022-05-05 Genentech, Inc. Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
US20220153842A1 (en) 2020-11-04 2022-05-19 Genentech, Inc. Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies and anti-cd79b antibody drug conjugates
WO2022098638A2 (en) 2020-11-04 2022-05-12 Genentech, Inc. Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
MX2023005130A (es) 2020-11-04 2023-05-25 Genentech Inc Dosis subcutanea de anticuerpos biespecificos anti-cd20/anti-cd3.
CA3202523A1 (en) 2020-12-02 2022-06-09 Genentech, Inc. Methods and compositions for neoadjuvant and adjuvant urothelial carcinoma therapy
EP4330282A1 (en) 2021-04-30 2024-03-06 F. Hoffmann-La Roche AG Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
WO2022232503A1 (en) 2021-04-30 2022-11-03 Genentech, Inc. Therapeutic and diagnostic methods and compositions for cancer
KR20240028452A (ko) 2021-07-02 2024-03-05 제넨테크, 인크. 암을 치료하기 위한 방법 및 조성물
MX2024001214A (es) 2021-07-28 2024-02-12 Hoffmann La Roche Metodos y composiciones para tratar cancer.
EP4377350A2 (en) 2021-07-28 2024-06-05 Genentech, Inc. Methods and compositions for treating cancer
MX2024003037A (es) * 2021-09-10 2024-07-30 Health Hope Pharma Ltd Combinaciones terapéuticas de paclitaxel administrado por vía oral, un inhibidor de p-gp, y un inhibidor de punto de control para el tratamiento de tumores sólidos.
TW202321308A (zh) 2021-09-30 2023-06-01 美商建南德克公司 使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
WO2023080900A1 (en) 2021-11-05 2023-05-11 Genentech, Inc. Methods and compositions for classifying and treating kidney cancer
JP2024541508A (ja) 2021-11-24 2024-11-08 ジェネンテック, インコーポレイテッド 治療用インダゾール化合物およびがんの治療における使用方法
US12275745B2 (en) 2021-11-24 2025-04-15 Genentech, Inc. Therapeutic compounds and methods of use
WO2023144973A1 (ja) 2022-01-27 2023-08-03 中外製薬株式会社 抗vegf抗体及びパクリタキセルと組み合わせて使用する抗pd-l1抗体を含む医薬組成物
WO2023191816A1 (en) 2022-04-01 2023-10-05 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
CA3251472A1 (en) 2022-05-11 2023-11-16 Genentech, Inc. DOSAGE FOR TREATMENT WITH ANTI-FCRH5/ANTI-CD3 BISPECIFIC ANTIBODIES
KR20250022049A (ko) 2022-06-07 2025-02-14 제넨테크, 인크. 항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법
CN119585308A (zh) 2022-07-13 2025-03-07 基因泰克公司 针对用抗fcrh5/抗cd3双特异性抗体进行的治疗的给药
EP4558524A1 (en) 2022-07-19 2025-05-28 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
CN120153254A (zh) 2022-09-01 2025-06-13 基因泰克公司 膀胱癌的治疗和诊断方法
WO2024077095A1 (en) 2022-10-05 2024-04-11 Genentech, Inc. Methods and compositions for classifying and treating bladder cancer
EP4599088A1 (en) 2022-10-05 2025-08-13 Genentech, Inc. Methods and compositions for classifying and treating lung cancer
WO2024091991A1 (en) 2022-10-25 2024-05-02 Genentech, Inc. Therapeutic and diagnostic methods for multiple myeloma
KR20250122520A (ko) 2022-12-20 2025-08-13 제넨테크, 인크. Pd-1 축 결합 길항제 및 rna 백신을 이용한 췌장암 치료 방법
AU2024270495A1 (en) 2023-05-05 2025-10-09 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
AU2024268933A1 (en) 2023-05-10 2025-11-20 Chugai Seiyaku Kabushiki Kaisha Methods and compositions for treating cancer
WO2024263904A1 (en) 2023-06-23 2024-12-26 Genentech, Inc. Methods for treatment of liver cancer
WO2024263195A1 (en) 2023-06-23 2024-12-26 Genentech, Inc. Methods for treatment of liver cancer
WO2025024257A1 (en) 2023-07-21 2025-01-30 Genentech, Inc. Diagnostic and therapeutic methods for cancer
WO2025049277A1 (en) 2023-08-25 2025-03-06 Genentech, Inc. Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist
WO2025085404A1 (en) 2023-10-16 2025-04-24 Genentech, Inc. Diagnostic and therapeutic methods for treating lung cancer
WO2025155607A1 (en) 2024-01-16 2025-07-24 Genentech, Inc. Methods of treating urothelial carcinoma with a pd-1 axis binding antagonist and an rna vaccine
WO2025174933A1 (en) 2024-02-14 2025-08-21 Genentech, Inc. Methods for treatment of pancreatic cancer with anti-pd-l1 ab, anti-tigit ab, gemcitabine and nab-placlitaxel

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595048B2 (en) * 2002-07-03 2009-09-29 Ono Pharmaceutical Co., Ltd. Method for treatment of cancer by inhibiting the immunosuppressive signal induced by PD-1
JP2008501654A (ja) * 2004-06-03 2008-01-24 エフ.ホフマン−ラ ロシュ アーゲー シスプラチンとegfr阻害剤を用いた治療
ES2700074T3 (es) 2006-12-14 2019-02-13 Abraxis Bioscience Llc Terapia para el cáncer de mama sobre la base del estado de los receptores hormonales con nanopartículas que comprenden taxano
ES2435452T3 (es) 2007-06-01 2013-12-19 Abraxis Bioscience, Llc Métodos y composiciones para tratar un cáncer recurrente
RS54233B1 (sr) * 2008-08-25 2015-12-31 Amplimmune Inc. Kompozicije pd-1 antagonista i postupci za njihovu primenu
JP6031437B2 (ja) 2010-06-07 2016-11-24 アブラクシス バイオサイエンス, エルエルシー 増殖性疾患を処置するための組み合わせ療法
MY193562A (en) * 2011-08-01 2022-10-19 Genentech Inc Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
WO2013138371A1 (en) * 2012-03-12 2013-09-19 Merrimack Pharmaceuticals, Inc. Methods for treating pancreatic cancer using combination therapies comprising an anti-erbb3 antibody
US9149455B2 (en) * 2012-11-09 2015-10-06 Abraxis Bioscience, Llc Methods of treating melanoma
FI3083686T4 (fi) * 2013-12-17 2023-05-09 Menetelmiä syöpien hoitamiseksi käyttäen pd-1-akselia sitovia antagonisteja ja taksaaneja
US20170202782A1 (en) * 2014-04-06 2017-07-20 Abraxis Bioscience, Llc Combination therapy comprising nanoparticles of a taxane and albumin with abt-263 in methods for treating cancer
CA2949121A1 (en) * 2014-05-15 2015-11-19 Bristol-Myers Squibb Company Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
CA2960824A1 (en) * 2014-09-13 2016-03-17 Novartis Ag Combination therapies of alk inhibitors
WO2016069727A1 (en) * 2014-10-29 2016-05-06 Five Prime Therapeutics, Inc. Combination therapy for cancer

Similar Documents

Publication Publication Date Title
JP2018501218A5 (OSRAM)
JP2021169479A5 (OSRAM)
JP2013520442A5 (OSRAM)
JP6695286B2 (ja) リンパ腫の処置
US20220144943A1 (en) Anti-cd47 antibodies and uses thereof
JP2019526578A5 (OSRAM)
JP2020527572A5 (OSRAM)
JP2017025090A5 (OSRAM)
CA2968680A1 (en) Combination therapies
JP2016536361A5 (OSRAM)
JP2012506448A5 (OSRAM)
JP2016502504A5 (OSRAM)
JP2017514795A5 (OSRAM)
JP2012509889A5 (OSRAM)
Tan et al. Randomized study of vinorelbine–gemcitabine versus vinorelbine–carboplatin in patients with advanced non-small cell lung cancer
JP2019517549A5 (OSRAM)
JP2019517498A5 (OSRAM)
JP2018522851A5 (OSRAM)
JP2019532970A5 (OSRAM)
Shiroyama et al. Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer
Ueda et al. Multicenter phase II study of weekly paclitaxel plus S-1 combination chemotherapy in patients with advanced gastric cancer
RS59704B1 (sr) Antitela protiv hpa-1a
JP2016511257A5 (OSRAM)
RS65871B1 (sr) Postupci lečenja her2-pozitivnog prethodno nelečenog metastatskog karcinoma dojke
CN119789867A (zh) 结合tim-3的抗体与结合pd-1的抗体的药物组合