JP2018500287A5 - - Google Patents

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Publication number
JP2018500287A5
JP2018500287A5 JP2017523358A JP2017523358A JP2018500287A5 JP 2018500287 A5 JP2018500287 A5 JP 2018500287A5 JP 2017523358 A JP2017523358 A JP 2017523358A JP 2017523358 A JP2017523358 A JP 2017523358A JP 2018500287 A5 JP2018500287 A5 JP 2018500287A5
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JP
Japan
Prior art keywords
disease
disorder
compound
pharmaceutically acceptable
pharmaceutical composition
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JP2017523358A
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English (en)
Japanese (ja)
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JP2018500287A (ja
JP6998204B2 (ja
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Priority claimed from PCT/US2015/058193 external-priority patent/WO2016069974A1/en
Publication of JP2018500287A publication Critical patent/JP2018500287A/ja
Publication of JP2018500287A5 publication Critical patent/JP2018500287A5/ja
Application granted granted Critical
Publication of JP6998204B2 publication Critical patent/JP6998204B2/ja
Expired - Fee Related legal-status Critical Current
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JP2017523358A 2014-10-30 2015-10-30 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール Expired - Fee Related JP6998204B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462072563P 2014-10-30 2014-10-30
US62/072,563 2014-10-30
PCT/US2015/058193 WO2016069974A1 (en) 2014-10-30 2015-10-30 TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2018200608A Division JP6623270B2 (ja) 2014-10-30 2018-10-25 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール
JP2020104927A Division JP2020180129A (ja) 2014-10-30 2020-06-18 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール

Publications (3)

Publication Number Publication Date
JP2018500287A JP2018500287A (ja) 2018-01-11
JP2018500287A5 true JP2018500287A5 (OSRAM) 2018-12-06
JP6998204B2 JP6998204B2 (ja) 2022-02-04

Family

ID=54754732

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017523358A Expired - Fee Related JP6998204B2 (ja) 2014-10-30 2015-10-30 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール
JP2018200608A Expired - Fee Related JP6623270B2 (ja) 2014-10-30 2018-10-25 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール
JP2020104927A Withdrawn JP2020180129A (ja) 2014-10-30 2020-06-18 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018200608A Expired - Fee Related JP6623270B2 (ja) 2014-10-30 2018-10-25 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール
JP2020104927A Withdrawn JP2020180129A (ja) 2014-10-30 2020-06-18 Rorγtのモジュレーターとしてのトリフルオロメチルアルコール

Country Status (40)

Country Link
US (2) US9850236B2 (OSRAM)
EP (2) EP3354651B1 (OSRAM)
JP (3) JP6998204B2 (OSRAM)
KR (2) KR20170078750A (OSRAM)
CN (3) CN112979630A (OSRAM)
AR (2) AR102480A1 (OSRAM)
AU (2) AU2015339087B2 (OSRAM)
BR (2) BR122017023050A2 (OSRAM)
CA (1) CA2965512C (OSRAM)
CL (3) CL2017001042A1 (OSRAM)
CO (1) CO2017005014A2 (OSRAM)
CR (2) CR20170166A (OSRAM)
CY (1) CY1121716T1 (OSRAM)
DK (1) DK3212643T3 (OSRAM)
EA (2) EA035998B1 (OSRAM)
EC (1) ECSP17033054A (OSRAM)
ES (2) ES2724556T3 (OSRAM)
GT (1) GT201700090A (OSRAM)
HR (1) HRP20190900T1 (OSRAM)
HU (1) HUE043624T2 (OSRAM)
IL (2) IL251865A0 (OSRAM)
JO (2) JOP20200117A1 (OSRAM)
LT (1) LT3212643T (OSRAM)
MA (1) MA40873B1 (OSRAM)
ME (1) ME03426B (OSRAM)
MX (2) MX369567B (OSRAM)
PE (2) PE20180250A1 (OSRAM)
PH (2) PH12017500800B1 (OSRAM)
PL (1) PL3212643T3 (OSRAM)
PT (1) PT3212643T (OSRAM)
RS (1) RS58613B1 (OSRAM)
SG (2) SG10201805355YA (OSRAM)
SI (1) SI3212643T1 (OSRAM)
SM (1) SMT201900290T1 (OSRAM)
SV (1) SV2017005429A (OSRAM)
TR (1) TR201907763T4 (OSRAM)
TW (2) TWI667230B (OSRAM)
UY (2) UY36377A (OSRAM)
WO (1) WO2016069974A1 (OSRAM)
ZA (3) ZA201703679B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201803869A (zh) 2016-04-27 2018-02-01 健生藥品公司 作為RORγT調節劑之6-胺基吡啶-3-基噻唑
JP2021517563A (ja) 2018-03-12 2021-07-26 エスカリア バイオサイエンシーズ,ビーブイ 二環式RORγモジュレーター
BR112020018718A2 (pt) 2018-03-12 2021-03-09 Escalier Biosciences B.V. Moduladores de ror-gama espirocíclicos
EP3807261B1 (en) 2018-06-18 2022-07-13 Janssen Pharmaceutica NV Pyridinyl pyrazoles as modulators of roryt
JP2021528405A (ja) 2018-06-18 2021-10-21 ヤンセン ファーマシューティカ エヌ.ベー. RORγtのモジュレータとしてのアミド置換チアゾール
US11345666B2 (en) 2018-06-18 2022-05-31 Janssen Pharmaceutica Nv Phenyl and pyridinyl substituted imidazoles as modulators of RORγT
EP3806958B1 (en) 2018-06-18 2022-09-07 Janssen Pharmaceutica NV 6-aminopyridin-3-yl pyrazoles as modulators of roryt
WO2023232870A1 (en) 2022-05-31 2023-12-07 Immunic Ag Rorg/rorgt modulators for the treatment of virus infections like covid-19
WO2024089216A1 (en) 2022-10-27 2024-05-02 Syngenta Crop Protection Ag Novel sulfur-containing heteroaryl carboxamide compounds
CN119528866B (zh) * 2024-11-28 2025-10-17 河南农业大学 一种含双三氟甲基的香豆素叔醇类化合物及其制备方法和应用

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91418A (en) 1988-09-01 1997-11-20 Rhone Poulenc Agrochimie (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them
WO1996003392A1 (en) 1994-07-27 1996-02-08 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
JP4073786B2 (ja) 2001-04-16 2008-04-09 田辺三菱製薬株式会社 高コンダクタンス型カルシウム感受性kチャネル開口薬
CN100502863C (zh) 2001-08-13 2009-06-24 詹森药业有限公司 2,4,5-三取代噻唑衍生物和它们的抗炎活性
AR045651A1 (es) * 2003-09-19 2005-11-02 Solvay Pharm Bv Derivados de tiazol como moduladores del receptor de cannabinoide
WO2006124687A1 (en) 2005-05-12 2006-11-23 University Of Medicine And Dentistry Of New Jersey Opioid receptor subtype-selective agents
GB0518237D0 (en) * 2005-09-07 2005-10-19 Angeletti P Ist Richerche Bio Therapeutic compounds
EP1983980A4 (en) 2006-01-25 2010-05-05 Synta Pharmaceuticals Corp THIAZOL AND THIADIAZOL COMPOUNDS FOR USES IN RELATION TO INFLAMMATION AND IMMUNITY
WO2008064317A1 (en) 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Lipophilic opioid receptor active compounds
WO2008064318A2 (en) 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Peripheral opioid receptor active compounds
WO2009011850A2 (en) 2007-07-16 2009-01-22 Abbott Laboratories Novel therapeutic compounds
MX2011000477A (es) 2008-07-17 2011-03-15 Bayer Cropscience Ag Compuestos heterociclicos como pesticidas.
JP2012523419A (ja) * 2009-04-08 2012-10-04 イデニク プハルマセウティカルス,インコーポレイテッド 大環状セリンプロテアーゼ阻害剤
AR079022A1 (es) 2009-11-02 2011-12-21 Sanofi Aventis Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
EP2368886A1 (en) * 2010-03-01 2011-09-28 Phenex Pharmaceuticals AG Novel compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (ROR gamma, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune desease
US9101600B2 (en) 2010-03-11 2015-08-11 New York University Compounds as RORγt modulators and uses thereof
WO2011112263A1 (en) 2010-03-11 2011-09-15 New York University AMIDO COMPOUNDS AS RORγt MODULATORS AND USES THEREOF
WO2011115892A1 (en) 2010-03-15 2011-09-22 Griffin Patrick R Modulators of the retinoic acid receptor-related orphan receptors
WO2012027965A1 (en) 2010-09-01 2012-03-08 Glaxo Group Limited Novel compounds
US9505798B2 (en) 2010-11-29 2016-11-29 New York University Steroid compounds as RORyt modulators and uses thereof
CN103282774B (zh) 2010-12-28 2015-08-05 狮王株式会社 口腔状态的判定方法及其所使用的分析用具、装置以及程序
US9012651B2 (en) 2011-03-24 2015-04-21 Abbvie Inc. TRPV3 modulators
WO2012158784A2 (en) 2011-05-16 2012-11-22 Theodore Mark Kamenecka Modulators of the nuclear hormone receptor ror
US9156837B2 (en) 2011-07-29 2015-10-13 Takeda Pharmaceutical Company Limited Heterocyclic compound
JP2014528933A (ja) 2011-09-09 2014-10-30 ニューヨーク ユニバーシティ RORγtモジュレーターとしてのアミド化合物およびその使用
GB201116641D0 (en) * 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
US9815851B2 (en) 2011-12-02 2017-11-14 Phenex Pharmaceuticals Ag Pyrrolo carboxamides as modulators of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases
US20130190356A1 (en) 2011-12-22 2013-07-25 Genentech, Inc. Benzyl sulfonamide derivatives as rorc modulators
WO2013178362A1 (en) * 2012-05-31 2013-12-05 Phenex Pharmaceuticals Ag Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ror[gamma]
JO3215B1 (ar) 2012-08-09 2018-03-08 Phenex Pharmaceuticals Ag حلقات غير متجانسة بها 5 ذرات تحتوي على النيتروجين بها استبدال بكربوكساميد أو سلفوناميد كمعدلات لمستقبل نووي غير محمي RORy
ES2628365T3 (es) * 2012-10-16 2017-08-02 Janssen Pharmaceutica N.V. Moduladores de quinolinilo unidos a fenilo de ROR-GAMA-T
EP2931281B1 (en) * 2012-12-12 2018-01-17 Merck Sharp & Dohme Corp. Amino-pyrimidine-containing spleen tyrosine kinase inhibitors
WO2014195321A1 (en) 2013-06-04 2014-12-11 Acturum Life Science AB Triazole compounds and their use as gamma secretase modulators
CN103333168B (zh) * 2013-07-23 2015-08-05 清华大学 一种酰胺类化合物及其制备方法与应用
CN105705501B (zh) 2013-09-09 2019-04-19 百时美施贵宝公司 RORγ调节剂
US20150072890A1 (en) 2013-09-11 2015-03-12 20/20 Gene Systems, Inc. Methods and compositions for aiding in the detection of lung cancer
CN105555768B (zh) 2013-09-20 2018-10-16 百时美施贵宝公司 RORγ调节剂
AU2014334619A1 (en) * 2013-10-15 2016-04-21 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORyt
CN105636952A (zh) * 2013-10-15 2016-06-01 詹森药业有限公司 Rorγt的仲醇喹啉基调节剂
PL3077372T3 (pl) 2013-12-05 2019-09-30 Lead Pharma Holding B.V. MODULATORY ROR GAMMA (RORγ)
CN106132931B (zh) 2014-01-06 2019-08-02 百时美施贵宝公司 碳环砜RORγ调节剂
CN106061947B (zh) 2014-01-06 2019-12-03 百时美施贵宝公司 环己基砜RORγ调节剂
MX369347B (es) 2014-01-06 2019-11-06 Bristol Myers Squibb Co Derivados de pirrolidinilsulfona y su uso como moduladores del receptor huerfano relacionado con retinoide gamma (ror gamma).
EP3092221B1 (en) 2014-01-06 2018-10-17 Bristol-Myers Squibb Company Heterocyclic sulfones as ror-gamma modulators
CA2942871A1 (en) 2014-03-27 2015-10-01 Piramal Enterprises Limited Ror-gamma modulators and uses thereof
PL3212641T3 (pl) 2014-10-30 2019-05-31 Janssen Pharmaceutica Nv Tiazole jako modulatory RORYT
DK3212642T3 (da) 2014-10-30 2019-11-25 Janssen Pharmaceutica Nv Amid-substituerede thiazoler som modulatorer af rorgammat

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