JP2018035162A5 - - Google Patents

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Publication number
JP2018035162A5
JP2018035162A5 JP2017172825A JP2017172825A JP2018035162A5 JP 2018035162 A5 JP2018035162 A5 JP 2018035162A5 JP 2017172825 A JP2017172825 A JP 2017172825A JP 2017172825 A JP2017172825 A JP 2017172825A JP 2018035162 A5 JP2018035162 A5 JP 2018035162A5
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JP
Japan
Prior art keywords
therapeutic agent
superoxide dismutase
agent according
administered
patient
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JP2017172825A
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English (en)
Japanese (ja)
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JP2018035162A (ja
JP6382416B2 (ja
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Publication of JP2018035162A5 publication Critical patent/JP2018035162A5/ja
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JP2017172825A 2011-09-26 2017-09-08 疾患の治療方法 Active JP6382416B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161539365P 2011-09-26 2011-09-26
US61/539,365 2011-09-26

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014532075A Division JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018145207A Division JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法

Publications (3)

Publication Number Publication Date
JP2018035162A JP2018035162A (ja) 2018-03-08
JP2018035162A5 true JP2018035162A5 (Direct) 2018-08-02
JP6382416B2 JP6382416B2 (ja) 2018-08-29

Family

ID=47911939

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2014532075A Active JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法
JP2017172825A Active JP6382416B2 (ja) 2011-09-26 2017-09-08 疾患の治療方法
JP2018145207A Active JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法
JP2020121417A Active JP7562125B2 (ja) 2011-09-26 2020-07-15 疾患の治療方法
JP2022200192A Active JP7697688B2 (ja) 2011-09-26 2022-12-15 疾患の治療方法
JP2025094341A Pending JP2025131753A (ja) 2011-09-26 2025-06-05 疾患の治療方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2014532075A Active JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018145207A Active JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法
JP2020121417A Active JP7562125B2 (ja) 2011-09-26 2020-07-15 疾患の治療方法
JP2022200192A Active JP7697688B2 (ja) 2011-09-26 2022-12-15 疾患の治療方法
JP2025094341A Pending JP2025131753A (ja) 2011-09-26 2025-06-05 疾患の治療方法

Country Status (8)

Country Link
US (5) US9149483B2 (Direct)
EP (1) EP2760874A4 (Direct)
JP (6) JP6267638B2 (Direct)
CN (2) CN111467351A (Direct)
AU (5) AU2012316397B2 (Direct)
CA (2) CA3120505C (Direct)
HK (1) HK1199261A1 (Direct)
WO (1) WO2013048965A1 (Direct)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE044234T2 (hu) 2006-10-12 2019-10-28 Galera Labs Llc Eljárások szájnyálkahártya-gyulladás kezelésére
WO2013048965A1 (en) 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases
TWI746449B (zh) * 2015-07-20 2021-11-21 美商Ａｉ治療公司 使用阿吡莫德治療癌症之方法
HRP20201092T1 (hr) * 2015-08-11 2020-10-30 Galera Labs, Llc Pentaaza makrociklički prstenasti kompleksi koji posjeduju oralnu biološku dostupnost
JP2019514962A (ja) * 2016-05-03 2019-06-06 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ 癌治療のための組み合わせ療法
EP3506907B1 (en) * 2016-09-01 2023-06-07 Galera Labs, LLC Combination cancer therapy with a pentaaza macrocyclic ring complex and an ascorbate compound
WO2018152353A2 (en) 2017-02-15 2018-08-23 Galera Labs, Llc Pentaaza macrocyclic ring complexes for local intestinal delivery
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
EP3746085A4 (en) * 2018-01-31 2022-03-09 Galera Labs, LLC COMBINATION OF CANCER THERAPY USING A PENTAAZA MACROCYCLIC RING COMPLEX AND A PLATINUM-BASED ANTI-CANCER AGENT
WO2021072359A1 (en) * 2019-10-10 2021-04-15 Galera Labs, Llc Manufacture method for aqueous formulation of manganese-containing coordination complex, formulation and method of treatment
EP4103573A1 (en) * 2020-02-13 2022-12-21 Teva Pharmaceuticals International GmbH Solid state forms of avasopasem manganese and process for preparation thereof
WO2025259817A1 (en) * 2024-06-12 2025-12-18 Galera Labs, Llc Methods for reduced tissue damage from radiopharmaceuticals with superoxide-reducing agent

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001212A (en) 1973-10-03 1977-01-04 E. I. Du Pont De Nemours And Company Macrocyclic polyamines
US3930867A (en) 1974-01-07 1976-01-06 E. I. Du Pont De Nemours And Company Macrocyclic polyamines as sensitizers for silver halide emulsions
JPS61226751A (ja) 1985-03-30 1986-10-08 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料用処理液及びその処理方法
US5033252A (en) 1987-12-23 1991-07-23 Entravision, Inc. Method of packaging and sterilizing a pharmaceutical product
US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
US5096724A (en) 1988-06-03 1992-03-17 Aquanautics Corporation Methods, compositions, and systems for ligand extraction
GB9001245D0 (en) 1990-01-19 1990-03-21 Salutar Inc Compounds
JP3155552B2 (ja) 1991-07-19 2001-04-09 モンサント カンパニー 超酸化物の不均斉変化に有効な触媒としての窒素含有−大環状リガンドのマンガン錯体
CA2072934C (en) 1991-07-19 2007-08-28 Karl William Aston Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US5323907A (en) 1992-06-23 1994-06-28 Multi-Comp, Inc. Child resistant package assembly for dispensing pharmaceutical medications
US6204259B1 (en) 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
CA2188530A1 (en) 1994-04-22 1995-11-02 John Charles Alexander Diagnostic image analysis with metal complexes
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
JPH0840941A (ja) 1994-07-29 1996-02-13 Kanegafuchi Chem Ind Co Ltd 炎症性腸疾患治療製剤
US6525041B1 (en) 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
CZ39898A3 (cs) * 1995-08-17 1998-07-15 Monsanto Company Biokonjugáty manganových komplexů makrocyklických ligandů obsahujících dusík účinné jako katalyzátory dismutace superoxidu
JPH11514971A (ja) 1995-08-17 1999-12-21 モンサント カンパニー 窒素含有大環状リガンドの金属錯体を使用する診断造影検査方法
WO1997006830A1 (en) 1995-08-17 1997-02-27 Monsanto Company Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
US6214817B1 (en) * 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
US6180620B1 (en) 1997-06-20 2001-01-30 G.D. Searle & Co. Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals
US20050171198A1 (en) 1997-06-20 2005-08-04 Metaphore Pharmaceuticals, Inc. SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease
US20060270639A1 (en) 1997-06-20 2006-11-30 Daniela Salvemini Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs
US20020128248A1 (en) 1997-06-20 2002-09-12 Metaphore Pharmaceuticals, Inc SODm therapy for prevention and/or treatment of inflammatory disease
JP2991172B2 (ja) 1997-10-24 1999-12-20 日本電気株式会社 半導体装置
WO1999023097A1 (en) 1997-11-03 1999-05-14 Duke University Substituted porphyrins
GB9817845D0 (en) 1998-08-17 1998-10-14 Glaxo Group Ltd Chemical compounds
US6040330A (en) * 1999-01-08 2000-03-21 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of taxanes
WO2000072893A2 (en) * 1999-05-27 2000-12-07 Monsanto Company Biomaterials modified with superoxide dismutase mimics
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
WO2000078316A1 (en) 1999-06-23 2000-12-28 Bernstein Eric F Use of nitroxides in wound healing and in the prevention of photodamage
EP2343047B2 (en) 2000-02-08 2021-03-17 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
US7279160B2 (en) 2000-05-02 2007-10-09 The Uab Research Foundation Combinations of DR5 antibodies and other therapeutic agents
EP1315481B1 (de) 2000-08-29 2006-12-06 Mepha AG Arzneimittel zur behandlung von darmerkrankungen
US7166910B2 (en) 2000-11-28 2007-01-23 Knowles Electronics Llc Miniature silicon condenser microphone
US6589948B1 (en) * 2000-11-28 2003-07-08 Eukarion, Inc. Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases
US20020072512A1 (en) 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
DE60235955D1 (de) 2001-01-05 2010-05-27 Metaphore Pharmaceuticals Inc Zusammensetzungen und verfahren zur erhöhung der zytokin-aktivität und zur behandlung der hypotension assoziiert mit der verabreichung von zytokinen
WO2002060383A2 (en) * 2001-01-19 2002-08-08 National Jewish Medical And Research Center Cancer therapy
AU2002236861A1 (en) 2001-01-26 2002-08-06 Metaphore Pharmaceuticals, Inc. Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes
RU2003129271A (ru) * 2001-03-02 2005-03-20 Метафор Фармасьютикалз, Инк. (Us) Хроматография комплексов металлов
US20040137638A1 (en) 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
WO2002100395A1 (en) 2001-06-08 2002-12-19 Genzyme Corporation Bismuth salts of anti-oxidants and radical scavengers for prevention and treatment of mucous membrane ulcers
US20040132706A1 (en) 2001-10-05 2004-07-08 Daniela Salvemini Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension
JP4663232B2 (ja) 2001-11-01 2011-04-06 ザ ユーエービー リサーチ ファウンデーション 腫瘍壊死因子関連アポトーシス誘導リガンドレセプターに対して選択的な抗体と他の治療剤の組み合わせ
SI1463563T1 (sl) * 2001-12-14 2009-06-30 Alcon Inc Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni
EP1501526A1 (en) 2002-04-16 2005-02-02 Isis Innovation Limited Curcumin for the prevention and/or treatment of tissue damage
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
US6781231B2 (en) 2002-09-10 2004-08-24 Knowles Electronics Llc Microelectromechanical system package with environmental and interference shield
US6798047B1 (en) 2002-12-26 2004-09-28 Amkor Technology, Inc. Pre-molded leadframe
WO2005042718A2 (en) 2003-10-31 2005-05-12 Metaphore Pharmaceuticals, Inc. Compositions and methods for treating, preventing, reversing and inhibiting pain
FR2863892B1 (fr) 2003-12-18 2007-05-11 Univ Paris Descartes Utilisation de mimetiques de la superoxyde dismutase et de la glutathion reductase comme anti-cancereux
US7510710B2 (en) 2004-01-08 2009-03-31 The Regents Of The University Of Colorado Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor
BRPI0509359A (pt) 2004-03-29 2007-09-04 Inotek Pharmaceuticals Corp compostos de porfirina substituìda por piridila e métodos de empregos destes
US7262498B2 (en) 2004-10-19 2007-08-28 Hewlett-Packard Development Company, L.P. Assembly with a ring and bonding pads formed of a same material on a substrate
US20070148154A1 (en) 2004-12-17 2007-06-28 Universite Rene Descartes (Paris V) Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs
US8217166B2 (en) 2005-05-05 2012-07-10 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
WO2006083508A2 (en) 2005-01-10 2006-08-10 Metaphore Pharmaceuticals Inc. Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs
US20090099150A1 (en) 2005-01-19 2009-04-16 Daniela Salvemini Methotrexate Combinations For Treating Inflammatory Diseases
WO2006105217A2 (en) 2005-03-31 2006-10-05 Schering Corporation Spirocyclic thrombin receptor antagonists
CN2870352Y (zh) 2005-12-23 2007-02-14 瑞声声学科技(深圳)有限公司 微机电系统传声器扣合式封装结构
US20100158857A1 (en) 2006-05-23 2010-06-24 University Of Utah Research Foundation Compositions and methods for the inhibition of endothelial nitric oxide synthase activity
US20080139525A1 (en) 2006-08-31 2008-06-12 The Brigham And Women's Hospital, Inc. Antioxidant therapies
WO2008033466A2 (en) 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions and methods for treatment of viral diseases
HUE044234T2 (hu) 2006-10-12 2019-10-28 Galera Labs Llc Eljárások szájnyálkahártya-gyulladás kezelésére
TWI333264B (en) 2007-01-10 2010-11-11 Advanced Semiconductor Eng Packaging structure and method of mems microphone
US20100210535A1 (en) * 2007-09-11 2010-08-19 Dorian Bevec Therapeutic use of neuropeptide ei and acth 7-38 and compositions thereof
MX2010009453A (es) 2008-02-29 2011-03-01 Eagle Pharmaceuticals Inc Soluciones de topotecano listas para utilizarse.
JP2011516610A (ja) * 2008-04-15 2011-05-26 インターミューン・インコーポレーテッド Ｃ型肝炎ウイルス複製の新規な阻害剤
WO2009143454A2 (en) * 2008-05-22 2009-11-26 Kereos, Inc. Combination antitumor therapy
KR20130049775A (ko) 2010-03-12 2013-05-14 애브비 바이오테라퓨틱스 인크. Ｃｔｌａ４ 단백질 및 이의 용도
US20120207687A1 (en) 2011-01-14 2012-08-16 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Topical formulations of targeted nitroxide agents
WO2013048965A1 (en) 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases
US9238659B2 (en) 2012-11-19 2016-01-19 The University Of Hong Kong Method of using binuclear gold (I) compounds for cancer treatment
HRP20201092T1 (hr) 2015-08-11 2020-10-30 Galera Labs, Llc Pentaaza makrociklički prstenasti kompleksi koji posjeduju oralnu biološku dostupnost
JP2019514962A (ja) 2016-05-03 2019-06-06 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ 癌治療のための組み合わせ療法
EP3506907B1 (en) 2016-09-01 2023-06-07 Galera Labs, LLC Combination cancer therapy with a pentaaza macrocyclic ring complex and an ascorbate compound
US20190350867A1 (en) 2016-12-27 2019-11-21 Soon Kap Hahn Prevention of local tumor recurrence following surgery using sustained and/or delayed release of medicaments contained in micro-particles
WO2018152353A2 (en) 2017-02-15 2018-08-23 Galera Labs, Llc Pentaaza macrocyclic ring complexes for local intestinal delivery
EP3388082A1 (en) 2017-04-13 2018-10-17 Galera Labs, LLC Combination cancer immunotherapy with pentaaza macrocyclic ring complex
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
EP3609510A4 (en) 2017-04-13 2021-03-10 Galera Labs, LLC COMBINED CANCER IMMUNOTHERAPY WITH MACROCYCLIC PENTAAZA RING COMPLEX
EP3746085A4 (en) 2018-01-31 2022-03-09 Galera Labs, LLC COMBINATION OF CANCER THERAPY USING A PENTAAZA MACROCYCLIC RING COMPLEX AND A PLATINUM-BASED ANTI-CANCER AGENT

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