JP2018033454A5 - - Google Patents
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- Publication number
- JP2018033454A5 JP2018033454A5 JP2017161826A JP2017161826A JP2018033454A5 JP 2018033454 A5 JP2018033454 A5 JP 2018033454A5 JP 2017161826 A JP2017161826 A JP 2017161826A JP 2017161826 A JP2017161826 A JP 2017161826A JP 2018033454 A5 JP2018033454 A5 JP 2018033454A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- humanized anti
- amino acid
- acid sequence
- htfr antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021200504A JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016164901 | 2016-08-25 | ||
| JP2016164901 | 2016-08-25 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021200504A Division JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018033454A JP2018033454A (ja) | 2018-03-08 |
| JP2018033454A5 true JP2018033454A5 (cg-RX-API-DMAC7.html) | 2020-06-25 |
| JP6993814B2 JP6993814B2 (ja) | 2022-01-14 |
Family
ID=61246169
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017161826A Active JP6993814B2 (ja) | 2016-08-25 | 2017-08-25 | 抗体融合蛋白質の製造方法 |
| JP2021200504A Active JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021200504A Active JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11512135B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3505538B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6993814B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102318480B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN109641971B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017316955B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019003622A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3034589A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX389073B (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201901495YA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018038243A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018000305A (es) | 2015-06-24 | 2018-03-14 | Japan Chem Res | Anticuerpo anti-receptor de transferrina humana que penetra la barrera hematoencefalica. |
| EP3315515A4 (en) | 2015-06-24 | 2019-06-05 | JCR Pharmaceuticals Co., Ltd. | HYBRID PROTEIN CONTAINING A BDNF |
| EA201991577A1 (ru) | 2016-12-26 | 2019-12-30 | Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. | Новые антитела против рецептора трансферрина человека, способные преодолевать гематоэнцефалический барьер |
| CA3052936A1 (en) | 2016-12-26 | 2018-07-05 | Jcr Pharmaceuticals Co., Ltd. | Fusion protein of bdnf and anti-transferrin receptor antibody |
| WO2019049967A1 (ja) * | 2017-09-07 | 2019-03-14 | Ｊｃｒファーマ株式会社 | 水性医薬組成物 |
| EP3692070A1 (en) | 2017-10-02 | 2020-08-12 | Denali Therapeutics Inc. | Fusion proteins comprising enzyme replacement therapy enzymes |
| IL276327B2 (en) * | 2018-02-05 | 2024-05-01 | Japan Chem Res | Method for delivering drug to muscle |
| EP3560945A1 (en) * | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
| JP6951051B2 (ja) * | 2018-05-24 | 2021-10-20 | ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 | 吸着剤の生産方法 |
| KR102692543B1 (ko) * | 2018-10-26 | 2024-08-07 | 재단법인 목암생명과학연구소 | Ids를 포함하는 융합 단백질 및 이의 용도 |
| KR20230086703A (ko) | 2020-10-14 | 2023-06-15 | 데날리 테라퓨틱스 인크. | 설포글루코사민 설포하이드롤라제 효소를 포함하는 융합 단백질 및 이의 방법 |
| JP2024500511A (ja) * | 2020-12-23 | 2024-01-09 | 広東菲鵬制▲薬▼股▲ふん▼有限公司 | 抗ｐｄ－ｌ１抗体及びその使用 |
| US20240148866A1 (en) * | 2021-02-11 | 2024-05-09 | Denali Therapeutics Inc. | Anti-transferrin receptor fusion proteins and methods of use thereof |
| WO2022191158A1 (ja) | 2021-03-09 | 2022-09-15 | Ｊｃｒファーマ株式会社 | 抗体－リソソーム酵素融合蛋白質の製造方法 |
| CN118475698A (zh) * | 2021-12-28 | 2024-08-09 | Jcr制药股份有限公司 | 用于安全的基因治疗的抗转铁蛋白受体抗体与具有生理活性的蛋白质的融合蛋白 |
| JPWO2024010067A1 (cg-RX-API-DMAC7.html) * | 2022-07-08 | 2024-01-11 | ||
| WO2025137213A1 (en) | 2023-12-20 | 2025-06-26 | Denali Therapeutics Inc. | Fusion proteins comprising acid alpha-glucosidase enzymes and methods thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007503838A (ja) * | 2003-09-05 | 2007-03-01 | ジーティーシー バイオセラピューティクス， インコーポレイティド | トランスジェニック動物の乳汁中での融合タンパク質の産生方法 |
| US20050100965A1 (en) * | 2003-11-12 | 2005-05-12 | Tariq Ghayur | IL-18 binding proteins |
| AR051805A1 (es) * | 2004-12-21 | 2007-02-07 | Centocor Inc | Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos |
| US20110105734A1 (en) | 2006-12-06 | 2011-05-05 | Jcr Pharmaceuticals Co., Ltd. | Method for production of human erythropoietin |
| WO2008072075A2 (en) * | 2006-12-12 | 2008-06-19 | Biorexis Pharmaceutical Corporation | Transferrin fusion protein libraries |
| JP2009273427A (ja) | 2008-05-16 | 2009-11-26 | Jcr Pharmaceuticals Co Ltd | 組換え体ヒトｆｓｈの製造方法 |
| WO2010051360A1 (en) | 2008-10-31 | 2010-05-06 | Wyeth Llc | Purification of acidic proteins using ceramic hydroxyapatite chromatography |
| HRP20190690T1 (hr) * | 2009-10-09 | 2019-06-28 | Armagen, Inc. | Postupci i pripravci za povećanje aktiviteta iduronat-2-sulfataze u centralnom nervnom sustavu |
| JP6018572B2 (ja) | 2011-01-25 | 2016-11-02 | Ｊｃｒファーマ株式会社 | 組換えヒトイズロン酸−２−スルファターゼの製造方法 |
| WO2012101671A1 (en) * | 2011-01-25 | 2012-08-02 | Jcr Pharmaceuticals Co., Ltd. | Method for production of human recombinant iduronate 2-sulfatase |
| HK1200190A1 (en) * | 2011-12-01 | 2015-07-31 | 安吉奥开米公司 | Targeted enzyme compounds and uses thereof |
| KR101380740B1 (ko) | 2012-06-29 | 2014-04-11 | 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 | 이듀로네이트-2-설파타제의 정제 |
| WO2014016873A1 (en) * | 2012-07-26 | 2014-01-30 | Jcr Pharmaceuticals Co., Ltd. | Method for production of recombinant human alpha-galactosidase a |
| JP6616189B2 (ja) * | 2013-12-25 | 2019-12-04 | Ｊｃｒファーマ株式会社 | 血液脳関門を通過する新規抗トランスフェリン受容体抗体 |
| EP3214172B1 (en) | 2014-10-31 | 2019-02-13 | JCR Pharmaceuticals CO., LTD. | Method for producing remcombinant human dnasei |
| WO2016116966A1 (en) | 2015-01-22 | 2016-07-28 | Jcr Pharmaceuticals Co., Ltd. | Method for purification of recombinant human alpha-galactosidase a from material containing contaminant host cell proteins |
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2017
- 2017-08-25 EP EP17843719.0A patent/EP3505538B1/en active Active
- 2017-08-25 BR BR112019003622-9A patent/BR112019003622A2/pt unknown
- 2017-08-25 MX MX2019002252A patent/MX389073B/es unknown
- 2017-08-25 CN CN201780051299.5A patent/CN109641971B/zh active Active
- 2017-08-25 AU AU2017316955A patent/AU2017316955B2/en active Active
- 2017-08-25 SG SG11201901495YA patent/SG11201901495YA/en unknown
- 2017-08-25 US US16/327,982 patent/US11512135B2/en active Active
- 2017-08-25 WO PCT/JP2017/030470 patent/WO2018038243A1/ja not_active Ceased
- 2017-08-25 JP JP2017161826A patent/JP6993814B2/ja active Active
- 2017-08-25 CA CA3034589A patent/CA3034589A1/en active Pending
- 2017-08-25 KR KR1020197007992A patent/KR102318480B1/ko active Active
-
2021
- 2021-12-10 JP JP2021200504A patent/JP7232889B2/ja active Active