JP2010515717A5 - - Google Patents
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- Publication number
- JP2010515717A5 JP2010515717A5 JP2009545252A JP2009545252A JP2010515717A5 JP 2010515717 A5 JP2010515717 A5 JP 2010515717A5 JP 2009545252 A JP2009545252 A JP 2009545252A JP 2009545252 A JP2009545252 A JP 2009545252A JP 2010515717 A5 JP2010515717 A5 JP 2010515717A5
- Authority
- JP
- Japan
- Prior art keywords
- beta
- seq
- antibody
- cdr2
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000029087 digestion Effects 0.000 claims description 4
- 229920001184 polypeptide Polymers 0.000 claims description 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 4
- 230000002797 proteolythic effect Effects 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 2
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88452607P | 2007-01-11 | 2007-01-11 | |
| US88451307P | 2007-01-11 | 2007-01-11 | |
| EP07000507A EP1944314A1 (en) | 2007-01-11 | 2007-01-11 | Diagnosis of Alzheimer's disease and other neurodementing disorders |
| EP07000521A EP1944315A1 (en) | 2007-01-11 | 2007-01-11 | Prophylaxis and therapy of alzheimer's disease and other neurodementing diseases |
| US98166707P | 2007-10-22 | 2007-10-22 | |
| US98167507P | 2007-10-22 | 2007-10-22 | |
| EP07119002 | 2007-10-22 | ||
| EP07119026 | 2007-10-22 | ||
| PCT/IB2008/000456 WO2008084402A2 (en) | 2007-01-11 | 2008-01-11 | Diagnosis and treatment of alzheimer's and other neurodementing diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010515717A JP2010515717A (ja) | 2010-05-13 |
| JP2010515717A5 true JP2010515717A5 (cg-RX-API-DMAC7.html) | 2011-03-31 |
Family
ID=39609117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545252A Pending JP2010515717A (ja) | 2007-01-11 | 2008-01-11 | アルツハイマーおよび他の神経性認知症疾患の診断ならびに処置 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US7939075B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2104682B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010515717A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008204335B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2675340C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2104682T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2610474T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2104682T3 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2104682T1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200844110A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008084402A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090280114A1 (en) * | 2002-04-12 | 2009-11-12 | Ramot At Tel Aviv University Ltd. | Prevention of brain inflammation as a result of induced autoimmune response |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| EP1954718B1 (en) | 2005-11-30 | 2014-09-03 | AbbVie Inc. | Anti-a globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2486928A1 (en) | 2007-02-27 | 2012-08-15 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| EP2143447A1 (en) * | 2008-07-11 | 2010-01-13 | Universität Konstanz | Bioconjugates comprising Aß-autoantibody-specific epitopes for active immunotherapy and diagnosis of Alzheimer's disease |
| AU2010216512B2 (en) * | 2009-02-20 | 2016-06-30 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| KR101095630B1 (ko) * | 2009-06-17 | 2011-12-19 | 주식회사 이노파마스크린 | 베타 아밀로이드 펩타이드와 ｖｅｇｆ의 상호작용을 억제하는 물질을 탐색 방법 및 그에 의해서 탐색된 저해제 |
| DE102009034119A1 (de) * | 2009-07-20 | 2011-01-27 | Philipps-Universität Marburg | Verfahren, insbesondere Enzyme-linked Immunosorbent Assay (ELISA), zum in vitro Nachweis von Amyloid beta Autoantikörpern, Mikrotiterplatte und Testkit |
| WO2011017600A2 (en) | 2009-08-07 | 2011-02-10 | American Life Science Pharmaceuticals, Inc. (Alsp Inc.) | Compositions and methods for treating beta-amyloid related diseases |
| WO2011130377A2 (en) | 2010-04-15 | 2011-10-20 | Abbott Laboratories | Amyloid-beta binding proteins |
| EP3533803B1 (en) | 2010-08-14 | 2021-10-27 | AbbVie Inc. | Anti-amyloid-beta antibodies |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| SI2579042T1 (sl) * | 2011-10-04 | 2014-09-30 | Affiris Ag | Postopek za detektiranje Ass-specifičnih protiteles v biološkem vzorcu |
| KR101190573B1 (ko) * | 2011-10-07 | 2012-10-18 | 대한민국 | 혈액 내 아밀로이드-베타 항체에 특이적으로 결합하는 신규 Ａβ２２（ｐＥ）－４２ 펩티드를 유효성분으로 포함하는 치매 진단용 키트 |
| CA2867338A1 (en) * | 2012-03-13 | 2013-09-19 | Janssen Alzheimer Immunotherapy | Oligomeric a.beta. in the diagnosis, prognosis, and monitoring of alzheimer's disease |
| AU2013203043B2 (en) * | 2013-03-15 | 2016-10-06 | Takeda Pharmaceutical Company Limited | Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs |
| US10942190B2 (en) | 2014-01-21 | 2021-03-09 | Shimadzu Corporation | Measurement method for amyloid precursor protein cleavage peptides |
| US11073470B2 (en) * | 2014-02-14 | 2021-07-27 | Betasense Gmbh | Attenuated total reflectance-based biosensor for conformation and secondary structure analysis |
| WO2016054114A1 (en) | 2014-09-29 | 2016-04-07 | The Regents Of The University Of California | Compositions for expanding regulatory t cells (treg), and treating autoimmune and inflammatory diseases and conditions |
| ES2663623T3 (es) * | 2015-01-12 | 2018-04-16 | Heraeus Deutschland GmbH & Co. KG | Uso de una composición eléctricamente conductora como adhesivo eléctricamente conductor para conectar mecánica y eléctricamente conductores eléctricos con los contactos eléctricos de células solares |
| ES2834484T3 (es) | 2016-11-21 | 2021-06-17 | Univ Ruhr Bochum | Método para la preselección de fármacos para enfermedades de plegamiento incorrecto de proteínas |
| AU2018308088B2 (en) | 2017-07-25 | 2025-05-29 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| EP3731867A4 (en) | 2017-12-19 | 2022-04-06 | Surrozen Operating, Inc. | Anti-lrp5/6 antibodies and methods of use |
| EP3732201A4 (en) | 2017-12-19 | 2022-04-20 | Surrozen Operating, Inc. | WNT SURROGATES AND THEIR USES |
| US12006368B2 (en) | 2017-12-19 | 2024-06-11 | Surrozen Operating, Inc. | Anti-frizzled antibodies and methods of use |
| CA3127113A1 (en) | 2019-01-30 | 2020-08-06 | Dongxu Sun | Anti-gal3 antibodies and uses thereof |
| AU2021278935A1 (en) | 2020-05-26 | 2022-12-08 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking Galectin-3 |
| KR20230109668A (ko) | 2020-11-16 | 2023-07-20 | 서로젠 오퍼레이팅, 인크. | 간-특이적 Wnt 신호 증강 분자 및 그의 용도 |
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| TW202300517A (zh) | 2021-03-12 | 2023-01-01 | 美商美國禮來大藥廠 | 抗類澱粉β抗體及其用途 |
| WO2022251048A1 (en) | 2021-05-24 | 2022-12-01 | Eli Lilly And Company | Anti-amyloid beta antibodies and uses thereof |
| AR133829A1 (es) | 2023-09-15 | 2025-11-05 | Othair Prothena Ltd | Agentes penetrantes de células y usos de los mismos |
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| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| CA1339014C (en) | 1987-10-08 | 1997-03-25 | Ronald E. Majocha | Antibodies to a4 amyloid peptide |
| EP0435911B1 (en) | 1988-09-23 | 1996-03-13 | Cetus Oncology Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
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| DK1136556T3 (da) | 1991-11-25 | 2005-10-03 | Enzon Inc | Fremgangsmåde til fremstilling af multivalente antigen-bindende proteiner |
| ATE239797T1 (de) * | 1993-01-25 | 2003-05-15 | Takeda Chemical Industries Ltd | Antikörper gegen beta-amyloid oder derivative davon und seine verwendung |
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| SI1481992T1 (sl) | 2000-02-24 | 2017-01-31 | Washington University St. Louis | Humanizirana protitelesa, ki vežejo amiloidni peptid beta |
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| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| KR101591223B1 (ko) | 2005-12-12 | 2016-02-04 | 에이씨 이뮨 에스.에이. | 치료적 특성을 갖는 베타 1-42 특이적인 단일클론성 항체 |
| EP2325209A3 (en) | 2006-03-23 | 2011-08-03 | BioArtic Neuroscience AB | Improved protofibril selective antibodies and the use thereof |
| CA2673771A1 (en) * | 2007-01-17 | 2008-07-24 | Merck Serono S.A. | Process for the purification of fc-containing proteins |
| CA2714413C (en) * | 2008-02-08 | 2017-01-24 | Immunas Pharma, Inc. | Antibody capable of binding specifically to ab-oligomer, and use thereof |
-
2008
- 2008-01-11 WO PCT/IB2008/000456 patent/WO2008084402A2/en not_active Ceased
- 2008-01-11 AU AU2008204335A patent/AU2008204335B2/en not_active Ceased
- 2008-01-11 CA CA2675340A patent/CA2675340C/en active Active
- 2008-01-11 SI SI200831731A patent/SI2104682T1/sl unknown
- 2008-01-11 ES ES08719192.0T patent/ES2610474T3/es active Active
- 2008-01-11 EP EP08719192.0A patent/EP2104682B1/en active Active
- 2008-01-11 JP JP2009545252A patent/JP2010515717A/ja active Pending
- 2008-01-11 TW TW097101288A patent/TW200844110A/zh unknown
- 2008-01-11 US US12/013,185 patent/US7939075B2/en active Active
- 2008-01-11 DK DK08719192.0T patent/DK2104682T3/en active
- 2008-01-11 PL PL08719192T patent/PL2104682T3/pl unknown
-
2011
- 2011-04-05 US US13/079,852 patent/US8491903B2/en active Active
- 2011-04-05 US US13/079,886 patent/US20120040382A1/en not_active Abandoned
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