JP2017538692A5 - - Google Patents
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- JP2017538692A5 JP2017538692A5 JP2017528156A JP2017528156A JP2017538692A5 JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5 JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nitrogen
- alkyl
- carbon
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1421020.7 | 2014-11-26 | ||
| GBGB1421020.7A GB201421020D0 (en) | 2014-11-26 | 2014-11-26 | Compounds |
| GB1516059.1 | 2015-09-10 | ||
| GBGB1516059.1A GB201516059D0 (en) | 2015-09-10 | 2015-09-10 | Compounds |
| PCT/EP2015/077821 WO2016083531A1 (en) | 2014-11-26 | 2015-11-26 | Compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538692A JP2017538692A (ja) | 2017-12-28 |
| JP2017538692A5 true JP2017538692A5 (cg-RX-API-DMAC7.html) | 2019-01-17 |
| JP7349773B2 JP7349773B2 (ja) | 2023-09-25 |
Family
ID=54705181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017528156A Active JP7349773B2 (ja) | 2014-11-26 | 2015-11-26 | 化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12146004B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3224273A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7349773B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107108699A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015352440B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2968902C (cg-RX-API-DMAC7.html) |
| TW (1) | TWI757229B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016083531A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107108699A (zh) * | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| WO2018006063A1 (en) * | 2016-07-01 | 2018-01-04 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
| US20190315806A1 (en) * | 2016-12-16 | 2019-10-17 | Institute Of Medicinal Biotechnology, Chinese Academy Of Medical Sciences | Polymyxin derivative, preparation method and application thereof |
| JP2021501783A (ja) * | 2017-11-02 | 2021-01-21 | ザ ユニバーシティー オブ クイーンズランド | ペプチド抗生物質 |
| LT3810633T (lt) | 2018-06-25 | 2024-01-10 | Spero Therapeutics, Inc. | Junginiai |
| CN111690040A (zh) * | 2019-03-12 | 2020-09-22 | 上海来益生物药物研究开发中心有限责任公司 | 多粘菌素衍生物、其制备方法和应用 |
| CN115298198A (zh) | 2020-01-21 | 2022-11-04 | 上海盟科药业股份有限公司 | 用于肾相关癌症靶向治疗的新型化合物和组合物 |
| CN111559992B (zh) * | 2020-05-29 | 2022-04-08 | 华中科技大学 | 一种2-芳基-γ-氨基丁酸衍生物的制备方法 |
| TW202233649A (zh) | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| WO2022206826A1 (zh) * | 2021-03-31 | 2022-10-06 | 江苏奥赛康药业有限公司 | 一种多粘菌素衍生物的硫酸盐及其药物组合物 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| AU7753787A (en) | 1986-08-06 | 1988-02-24 | Jean-Luc Fauchere | Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (cg-RX-API-DMAC7.html) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| EP1667648A2 (en) | 2003-09-30 | 2006-06-14 | Kohi Corporation | Compositions and methods for treating burns |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US7807637B2 (en) * | 2006-08-11 | 2010-10-05 | Northern Antibiotics Oy | Polymyxin derivatives and uses thereof |
| SI2057185T1 (sl) | 2006-08-11 | 2016-10-28 | Northern Antibiotics Oy | Derivati polimiksina in njihove uporabe |
| FI20085469A0 (fi) | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| US8329645B2 (en) * | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| WO2010075416A1 (en) | 2008-12-23 | 2010-07-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) * | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| CA2855916A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| PT2999711T (pt) | 2013-05-22 | 2022-07-29 | Spero Therapeutics Inc | Derivados de polimixina e a sua utilização em terapia de combinação em conjunto com antibióticos diferentes |
| US20170073373A1 (en) | 2014-03-11 | 2017-03-16 | New Pharma Licence Holdings Limited | Polymyxin derivatives and their use in combination therapy together with different antibiotics |
| EP3126376B1 (en) * | 2014-04-01 | 2024-08-21 | Monash University | Polymyxin derivatives as antimicrobial compounds |
| CN107108699A (zh) * | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| WO2016166103A1 (en) | 2015-04-13 | 2016-10-20 | Xellia Pharmaceuticals Aps | Polymyxin derivatives |
| CN108350034B (zh) | 2015-09-29 | 2022-03-11 | 莫纳什大学 | 抗微生物的多黏菌素衍生的化合物 |
| LT3810633T (lt) | 2018-06-25 | 2024-01-10 | Spero Therapeutics, Inc. | Junginiai |
-
2015
- 2015-11-26 CN CN201580072906.7A patent/CN107108699A/zh active Pending
- 2015-11-26 US US15/529,786 patent/US12146004B2/en active Active
- 2015-11-26 AU AU2015352440A patent/AU2015352440B2/en active Active
- 2015-11-26 JP JP2017528156A patent/JP7349773B2/ja active Active
- 2015-11-26 TW TW104139459A patent/TWI757229B/zh active
- 2015-11-26 WO PCT/EP2015/077821 patent/WO2016083531A1/en not_active Ceased
- 2015-11-26 EP EP15801162.7A patent/EP3224273A1/en not_active Withdrawn
- 2015-11-26 CA CA2968902A patent/CA2968902C/en active Active
-
2023
- 2023-04-25 US US18/139,030 patent/US20230340026A1/en not_active Abandoned
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