JP2017537926A - Ｋｌｏｔｈｏ変種ポリペプチドを使用する方法および組成物 - Google Patents

Ｋｌｏｔｈｏ変種ポリペプチドを使用する方法および組成物 Download PDF

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JP2017537926A
JP2017537926A JP2017529778A JP2017529778A JP2017537926A JP 2017537926 A JP2017537926 A JP 2017537926A JP 2017529778 A JP2017529778 A JP 2017529778A JP 2017529778 A JP2017529778 A JP 2017529778A JP 2017537926 A JP2017537926 A JP 2017537926A
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klotho
seq
fgf23
sklotho
fusion
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JP2017537926A5 (enExample
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グオ，ドンリン
イベブンジョ，チクウェンデュ
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ノバルティス アーゲー
ノバルティス アーゲー
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JP2017529778A 2014-12-04 2015-12-02 Ｋｌｏｔｈｏ変種ポリペプチドを使用する方法および組成物 Pending JP2017537926A (ja)

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US201462087516P 2014-12-04 2014-12-04
US62/087,516 2014-12-04
PCT/IB2015/059294 WO2016088059A1 (en) 2014-12-04 2015-12-02 Methods and compositions using klotho variant polypeptides

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JP2017537926A true JP2017537926A (ja) 2017-12-21
JP2017537926A5 JP2017537926A5 (enExample) 2019-01-17

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US (2) US10654909B2 (enExample)
EP (1) EP3227319B1 (enExample)
JP (1) JP2017537926A (enExample)
KR (1) KR20170084332A (enExample)
CN (1) CN107810201A (enExample)
AU (1) AU2015356643B2 (enExample)
BR (1) BR112017011398A2 (enExample)
CA (1) CA2969307A1 (enExample)
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WO2018098375A1 (en) * 2016-11-22 2018-05-31 Klotho Therapeutics, Inc. Novel recombinant klotho proteins and compositions and methods involving the same
CA3069143A1 (en) 2017-07-06 2019-01-10 Yale University Compositions and methods for treating or preventing endocrine fgf-linked diseases
JP2021506792A (ja) * 2017-12-13 2021-02-22 イエール ユニバーシティ 内分泌型ｆｇｆ２３関連疾患を処置または防止するための組成物および方法
US12227777B2 (en) * 2018-01-12 2025-02-18 New York University Soluble alpha-Klotho proteins, protein fragments, and uses thereof
US20220008520A1 (en) * 2018-11-21 2022-01-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and materials for reducing age-related striated muscle and cognitive decline
CN112695049A (zh) * 2020-08-20 2021-04-23 山东兴瑞生物科技有限公司 修饰间充质干细胞的融合基因、质粒、修饰得到干细胞及制备方法
CN112915193B (zh) * 2021-03-05 2022-09-13 南方医科大学南方医院 Kp-1在制备治疗慢性肺病的药物中的用途
CN112915192B (zh) * 2021-03-05 2022-10-25 南方医科大学南方医院 Kp-1在制备治疗慢性肝病的药物中的用途
EP4395807A4 (en) * 2021-09-03 2025-09-24 Uab Res Found COMPOUNDS MODULATING FIBROBLAST GROWTH FACTOR 23
WO2024168241A2 (en) * 2023-02-10 2024-08-15 The Trustees Of Indiana University Stabilized fgf23 fusion proteins, compositions and a targeted therapy for hyperphosphatemia
EP4434534A1 (en) 2023-03-22 2024-09-25 ADvantage Therapeutics, Inc. Klotho mrna
AU2024377885A1 (en) * 2023-11-10 2026-05-28 Regeneron Pharmaceuticals, Inc. Engineered alpha klotho polypeptides and uses thereof
US20250376667A1 (en) * 2024-06-07 2025-12-11 Regeneron Pharmaceuticals, Inc. Engineered alpha klotho polypeptides and uses thereof
CN122356258B (zh) * 2026-06-05 2026-08-11 广州集妍化妆品科技有限公司 寡肽及其在制备抗衰老的产品中的应用

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