JP2017537888A5 - - Google Patents

Download PDF

Info

Publication number
JP2017537888A5
JP2017537888A5 JP2017522654A JP2017522654A JP2017537888A5 JP 2017537888 A5 JP2017537888 A5 JP 2017537888A5 JP 2017522654 A JP2017522654 A JP 2017522654A JP 2017522654 A JP2017522654 A JP 2017522654A JP 2017537888 A5 JP2017537888 A5 JP 2017537888A5
Authority
JP
Japan
Prior art keywords
polypeptide
fusion protein
seq
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017522654A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017537888A (ja
JP6737781B2 (ja
Filing date
Publication date
Priority claimed from US14/524,832 external-priority patent/US10400029B2/en
Application filed filed Critical
Priority claimed from PCT/US2015/057533 external-priority patent/WO2016069574A1/en
Publication of JP2017537888A publication Critical patent/JP2017537888A/ja
Publication of JP2017537888A5 publication Critical patent/JP2017537888A5/ja
Application granted granted Critical
Publication of JP6737781B2 publication Critical patent/JP6737781B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017522654A 2014-10-27 2015-10-27 セルピン融合ポリペプチド及びその使用方法 Active JP6737781B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/524,832 2014-10-27
US14/524,832 US10400029B2 (en) 2011-06-28 2014-10-27 Serpin fusion polypeptides and methods of use thereof
PCT/US2015/057533 WO2016069574A1 (en) 2014-10-27 2015-10-27 Serpin fusion polypeptides and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020121953A Division JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Publications (3)

Publication Number Publication Date
JP2017537888A JP2017537888A (ja) 2017-12-21
JP2017537888A5 true JP2017537888A5 (enExample) 2018-10-25
JP6737781B2 JP6737781B2 (ja) 2020-08-12

Family

ID=55858243

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017522654A Active JP6737781B2 (ja) 2014-10-27 2015-10-27 セルピン融合ポリペプチド及びその使用方法
JP2020121953A Pending JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020121953A Pending JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Country Status (15)

Country Link
EP (1) EP3212290A4 (enExample)
JP (2) JP6737781B2 (enExample)
KR (2) KR20170091096A (enExample)
CN (2) CN107206257A (enExample)
AU (3) AU2015339507B2 (enExample)
BR (1) BR112017008525A2 (enExample)
CA (1) CA2965151A1 (enExample)
HK (1) HK1244460A1 (enExample)
IL (2) IL251799B2 (enExample)
MX (2) MX2017005467A (enExample)
NZ (1) NZ769391A (enExample)
RU (1) RU2746550C2 (enExample)
SG (2) SG10201903142RA (enExample)
UA (1) UA127305C2 (enExample)
WO (1) WO2016069574A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020092448A1 (en) * 2018-10-29 2020-05-07 Spin Therapeutics, Llc Compositions and methods for alpha-1-antitrypsin disorders
WO2020097946A1 (zh) * 2018-11-18 2020-05-22 杭州博虎生物科技有限公司 一种重组人白细胞介素10融合蛋白及其应用
US12649769B2 (en) 2019-09-16 2026-06-09 Zensun (Shanghai) Science & Technology, Co., Ltd. Recombinant human neuregulin derivatives and use thereof
CN112315897A (zh) * 2020-11-04 2021-02-05 深圳前海鹰岗生物科技有限公司 一种抑制细胞炎症反应释放治疗痛风急性发作的聚合物微针及制备方法
WO2022133521A1 (en) * 2020-12-21 2022-06-30 Macquarie University Treatment of glaucoma
GB202102258D0 (en) * 2021-02-17 2021-03-31 Arecor Ltd Novel composition
CA3205815A1 (en) * 2021-03-03 2022-09-09 Alwin REITER Formulations of ace2 fc fusion proteins
CN113325181A (zh) * 2021-04-25 2021-08-31 苏州市立医院(北区) 丝氨酸蛋白酶抑制剂在用于脓毒症早期预警的标志物中的应用
CN114874333B (zh) * 2021-10-18 2025-01-24 深圳科兴药业有限公司 一种生长激素融合蛋白及其应用
WO2023225513A1 (en) 2022-05-16 2023-11-23 Inhibrx, Inc. Effective dosage of recombinant serpin-fc fusion protein for use in a method of treating aat deficiency in a subject
JP2026502133A (ja) * 2022-12-22 2026-01-21 ライフアーク ガラニン-2受容体アゴニスト
EP4705336A1 (en) * 2023-05-05 2026-03-11 Paul Thomas King Novel therapeutic polypeptide

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537810A (ja) * 1999-03-01 2002-11-12 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド ヒトセルピンタンパク質
US7317091B2 (en) * 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
US7217797B2 (en) * 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
US7109172B2 (en) * 2003-07-18 2006-09-19 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
DK2520654T3 (en) * 2003-08-26 2017-05-01 Univ Colorado Regents Inhibitors of serine protease activity and their use in methods and compositions for the treatment of bacterial infections
US8802820B2 (en) * 2004-11-12 2014-08-12 Xencor, Inc. Fc variants with altered binding to FcRn
US9200079B2 (en) * 2004-11-12 2015-12-01 Xencor, Inc. Fc variants with altered binding to FcRn
NZ565511A (en) * 2005-07-22 2011-03-31 Five Prime Therapeutics Inc Compositions and methods of treating disease with FGFR fusion proteins
WO2007021807A1 (en) * 2005-08-12 2007-02-22 Schering Corporation Mcp1 fusions
WO2009158432A2 (en) * 2008-06-27 2009-12-30 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
JP5734201B2 (ja) * 2008-12-19 2015-06-17 マクロジェニクス,インコーポレーテッド 共有結合型ダイアボディ及びその使用
SG191233A1 (en) * 2010-12-23 2013-07-31 Janssen Biotech Inc Active protease-resistant antibody fc mutants
LT2691417T (lt) * 2011-03-29 2018-10-25 Roche Glycart Ag Antikūno fc variantai
SMT201900520T1 (it) * 2011-06-28 2019-11-13 Inhibrx Lp Polipeptidi di fusione serpinici e relativi metodi d'uso
RU2639526C2 (ru) * 2011-06-28 2017-12-21 ИНХИБРКС ЭлЭлСи Слитые полипептиды, содержащие домен wap, и способы их применения
KR20140137347A (ko) * 2012-01-10 2014-12-02 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 알파-1 안티트립신 융합 분자용 조성물, 방법 및 용도
MX2014015557A (es) * 2012-06-21 2015-02-24 Univ Indiana Res & Tech Corp Polipeptidos de fusion de region fc de polipeptido de ligando receptor de incretina y conjugados con función efectora fc alterada.
KR20150030744A (ko) * 2012-06-27 2015-03-20 에프. 호프만-라 로슈 아게 표적에 특이적으로 결합하는 하나 이상의 결합 단위를 포함하는 항체 Fc-영역 접합체의 제조 방법 및 그의 용도
CA2876096A1 (en) * 2012-08-02 2014-02-06 Petra Rueger Method for producing soluble fcr as fc-fusion with inert immunoglobulin fc-region and uses thereof
EP2929045B1 (en) * 2012-12-05 2020-12-02 SOLA Biosciences LLC Protein expression enhancing polypeptides

Similar Documents

Publication Publication Date Title
RU2017118325A (ru) Слитые серпиновые полипептиды и способы их применения
JP2024138397A5 (enExample)
NZ744257A (en) Serpin fusion polypeptides and methods of use thereof
JP6920230B2 (ja) アルファ−1アンチトリプシン融合ポリペプチド、それをコードする核酸構築体、及びそれらの組成物
JP2022043042A5 (enExample)
JP6216921B2 (ja) アルファ−1抗トリプシン融合分子のための組成物、方法および使用
JP2010524971A5 (enExample)
JP2018070625A5 (enExample)
CN113173995B (zh) 一种结合冠状病毒的双特异性抗体
JP2023504914A5 (enExample)
CN104114574B (zh) 结合人补体c5的多肽
JP2015504675A5 (enExample)
JP2012505902A5 (enExample)
JP6938565B2 (ja) Uti融合タンパク質
JP2014530611A5 (enExample)
JP2018537087A5 (enExample)
JP2008507298A5 (enExample)
CN103396479A (zh) α-1-抗胰蛋白酶和载脂蛋白A-I的纯化方法
JP2022509517A5 (enExample)
JP2007509984A5 (enExample)
JP2020019813A5 (enExample)
CN107226842B (zh) 靶向pd-1的多肽及其应用
JP2022530742A5 (enExample)
JP2009507503A5 (enExample)
CN102690354A (zh) 重组二聚化抗凝血酶III-Fc融合蛋白及其哺乳动物细胞高效表达系统