JP2017537888A5 - - Google Patents

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Publication number
JP2017537888A5
JP2017537888A5 JP2017522654A JP2017522654A JP2017537888A5 JP 2017537888 A5 JP2017537888 A5 JP 2017537888A5 JP 2017522654 A JP2017522654 A JP 2017522654A JP 2017522654 A JP2017522654 A JP 2017522654A JP 2017537888 A5 JP2017537888 A5 JP 2017537888A5
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JP
Japan
Prior art keywords
polypeptide
fusion protein
seq
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017522654A
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English (en)
Japanese (ja)
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JP6737781B2 (ja
JP2017537888A (ja
Filing date
Publication date
Priority claimed from US14/524,832 external-priority patent/US10400029B2/en
Application filed filed Critical
Priority claimed from PCT/US2015/057533 external-priority patent/WO2016069574A1/en
Publication of JP2017537888A publication Critical patent/JP2017537888A/ja
Publication of JP2017537888A5 publication Critical patent/JP2017537888A5/ja
Application granted granted Critical
Publication of JP6737781B2 publication Critical patent/JP6737781B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017522654A 2014-10-27 2015-10-27 セルピン融合ポリペプチド及びその使用方法 Active JP6737781B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/524,832 US10400029B2 (en) 2011-06-28 2014-10-27 Serpin fusion polypeptides and methods of use thereof
US14/524,832 2014-10-27
PCT/US2015/057533 WO2016069574A1 (en) 2014-10-27 2015-10-27 Serpin fusion polypeptides and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020121953A Division JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Publications (3)

Publication Number Publication Date
JP2017537888A JP2017537888A (ja) 2017-12-21
JP2017537888A5 true JP2017537888A5 (enExample) 2018-10-25
JP6737781B2 JP6737781B2 (ja) 2020-08-12

Family

ID=55858243

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017522654A Active JP6737781B2 (ja) 2014-10-27 2015-10-27 セルピン融合ポリペプチド及びその使用方法
JP2020121953A Pending JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020121953A Pending JP2020180157A (ja) 2014-10-27 2020-07-16 セルピン融合ポリペプチド及びその使用方法

Country Status (15)

Country Link
EP (1) EP3212290A4 (enExample)
JP (2) JP6737781B2 (enExample)
KR (2) KR20170091096A (enExample)
CN (2) CN107206257A (enExample)
AU (3) AU2015339507B2 (enExample)
BR (1) BR112017008525A2 (enExample)
CA (1) CA2965151A1 (enExample)
HK (1) HK1244460A1 (enExample)
IL (2) IL308589A (enExample)
MX (2) MX2017005467A (enExample)
NZ (1) NZ769391A (enExample)
RU (1) RU2746550C2 (enExample)
SG (2) SG11201703390SA (enExample)
UA (1) UA127305C2 (enExample)
WO (1) WO2016069574A1 (enExample)

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CA3117961A1 (en) * 2018-10-29 2020-05-07 Spin Therapeutics, Llc Compositions and methods for alpha-1-antitrypsin disorders
CN111989340B (zh) * 2018-11-18 2025-07-15 杭州博虎生物科技有限公司 一种重组人白细胞介素-10融合蛋白及其应用
CN112315897A (zh) * 2020-11-04 2021-02-05 深圳前海鹰岗生物科技有限公司 一种抑制细胞炎症反应释放治疗痛风急性发作的聚合物微针及制备方法
WO2022133521A1 (en) * 2020-12-21 2022-06-30 Macquarie University Treatment of glaucoma
GB202102258D0 (en) * 2021-02-17 2021-03-31 Arecor Ltd Novel composition
EP4301333A2 (en) * 2021-03-03 2024-01-10 Formycon AG Formulations of ace2 fc fusion proteins
CN113325181A (zh) * 2021-04-25 2021-08-31 苏州市立医院(北区) 丝氨酸蛋白酶抑制剂在用于脓毒症早期预警的标志物中的应用
CN119638849A (zh) * 2021-10-18 2025-03-18 深圳科兴药业有限公司 一种生长激素融合蛋白及其应用
AU2023272089A1 (en) 2022-05-16 2025-01-09 Sanofi Aatd Inc. Effective dosage of recombinant serpin-fc fusion protein for use in a method of treating aat deficiency in a subject
AU2024219542B1 (en) * 2023-05-05 2024-10-03 Ashley Maurice Buckle Novel therapeutic polypeptide

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052160A1 (en) * 1999-03-01 2000-09-08 Human Genome Sciences, Inc. Human serpin proteins
US7317091B2 (en) * 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
US7217797B2 (en) * 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
BRPI0412761A (pt) * 2003-07-18 2006-09-26 Vertex Pharma inibidores de serino proteases, particularmente a protease ns3-ns4a do vhc
PL2520654T3 (pl) * 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
BRPI0517837A (pt) * 2004-11-12 2008-10-21 Xencor Inc variantes fc com ligação alterada a fcrn
US8802820B2 (en) * 2004-11-12 2014-08-12 Xencor, Inc. Fc variants with altered binding to FcRn
ES2336832T3 (es) * 2005-07-22 2010-04-16 Five Prime Therapeutics, Inc. Composiciones y procedimientos para tratar enfermedades con proteinas de fusion de fgfr.
US7713521B2 (en) * 2005-08-12 2010-05-11 Schering Corporation MCP1 fusions
AU2009262199B2 (en) * 2008-06-27 2012-08-09 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
ES2733067T3 (es) * 2008-12-19 2019-11-27 Macrogenics Inc Diacuerpos covalentes y usos de los mismos
CA2822366A1 (en) * 2010-12-23 2012-06-28 Janssen Biotech, Inc. Active protease-resistant antibody fc mutants
ES2692268T5 (en) * 2011-03-29 2025-02-26 Roche Glycart Ag Antibody fc variants
SG10201601621PA (en) * 2011-06-28 2016-04-28 Inhibrx Llc Serpin fusion polypeptides and methods of use thereof
CN103946388A (zh) * 2011-06-28 2014-07-23 英伊布里克斯有限责任公司 Wap结构域融合多肽及其使用方法
JP2015504675A (ja) * 2012-01-10 2015-02-16 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate アルファ−1アンチトリプシン融合分子の組成物、方法、及び使用
HK1209034A1 (en) * 2012-06-21 2016-03-24 Indiana University Research And Technology Corporation Incretin receptor ligand polypeptide fc-region fusion polypeptides and conjugates with altered fc-effector function
MX2014014804A (es) * 2012-06-27 2015-02-12 Hoffmann La Roche Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
HUE029634T2 (en) * 2012-08-02 2017-03-28 Hoffmann La Roche A method for producing soluble FcR as an Fc fusion with an inert immunoglobulin Fc region and its uses
CA2893359C (en) * 2012-12-05 2021-12-28 Strategia Therapeutics, Inc. Protein expression enhancing polypeptides

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