JP2017535527A - 新規のα４β７ペプチド単量体及び二量体拮抗薬 - Google Patents

新規のα４β７ペプチド単量体及び二量体拮抗薬 Download PDF

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JP2017535527A
JP2017535527A JP2017517669A JP2017517669A JP2017535527A JP 2017535527 A JP2017535527 A JP 2017535527A JP 2017517669 A JP2017517669 A JP 2017517669A JP 2017517669 A JP2017517669 A JP 2017517669A JP 2017535527 A JP2017535527 A JP 2017535527A
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JP2017535527A5 (OSRAM
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アショク バンダーリー，
アショク バンダーリー，
ディネシュ ブイ． パテル，
ディネシュ ブイ． パテル，
ジュネ ゼメデ，
ジュネ ゼメデ，
ラリー シー． マシアキス，
ラリー シー． マシアキス，
デイビッド リウ，
デイビッド リウ，
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プロタゴニスト セラピューティクス， インコーポレイテッド
プロタゴニスト セラピューティクス， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P11/02—Nasal agents, e.g. decongestants
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    • A61P11/06—Antiasthmatics
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P37/02—Immunomodulators
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
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  • Diabetes (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
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JP2017517669A 2014-10-01 2015-10-01 新規のα４β７ペプチド単量体及び二量体拮抗薬 Pending JP2017535527A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462058510P 2014-10-01 2014-10-01
US201462058506P 2014-10-01 2014-10-01
US62/058,506 2014-10-01
US62/058,510 2014-10-01
US201562149257P 2015-04-17 2015-04-17
US62/149,257 2015-04-17
US201562192934P 2015-07-15 2015-07-15
US62/192,934 2015-07-15
PCT/US2015/053558 WO2016054411A1 (en) 2014-10-01 2015-10-01 NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS

Publications (2)

Publication Number Publication Date
JP2017535527A true JP2017535527A (ja) 2017-11-30
JP2017535527A5 JP2017535527A5 (OSRAM) 2018-11-08

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JP2017517669A Pending JP2017535527A (ja) 2014-10-01 2015-10-01 新規のα４β７ペプチド単量体及び二量体拮抗薬

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US (5) US9809623B2 (OSRAM)
EP (1) EP3200812B8 (OSRAM)
JP (1) JP2017535527A (OSRAM)
KR (1) KR20170108936A (OSRAM)
CN (1) CN106999537B (OSRAM)
AU (1) AU2015328002A1 (OSRAM)
BR (1) BR112017006826A2 (OSRAM)
CA (1) CA2962642A1 (OSRAM)
IL (1) IL251260A0 (OSRAM)
MX (1) MX391184B (OSRAM)
RU (1) RU2017114414A (OSRAM)
SG (1) SG11201702553RA (OSRAM)
WO (1) WO2016054411A1 (OSRAM)

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