JP2017531613A5 - - Google Patents
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- Publication number
- JP2017531613A5 JP2017531613A5 JP2017500335A JP2017500335A JP2017531613A5 JP 2017531613 A5 JP2017531613 A5 JP 2017531613A5 JP 2017500335 A JP2017500335 A JP 2017500335A JP 2017500335 A JP2017500335 A JP 2017500335A JP 2017531613 A5 JP2017531613 A5 JP 2017531613A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- subject
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059682P | 2014-10-03 | 2014-10-03 | |
| US62/059,682 | 2014-10-03 | ||
| PCT/US2015/053700 WO2016054494A1 (en) | 2014-10-03 | 2015-10-02 | Methods and compositions for treatment of conditions associated with elevated triglycerides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531613A JP2017531613A (ja) | 2017-10-26 |
| JP2017531613A5 true JP2017531613A5 (enExample) | 2018-11-08 |
| JP6680758B2 JP6680758B2 (ja) | 2020-04-15 |
Family
ID=55631597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500335A Expired - Fee Related JP6680758B2 (ja) | 2014-10-03 | 2015-10-02 | 上昇したトリグリセリドと関連する状態の治療のための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10071139B2 (enExample) |
| EP (2) | EP3822287A1 (enExample) |
| JP (1) | JP6680758B2 (enExample) |
| AU (1) | AU2015327900B2 (enExample) |
| CA (1) | CA2954082A1 (enExample) |
| ES (1) | ES2819866T3 (enExample) |
| WO (1) | WO2016054494A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3822287A1 (en) | 2014-10-03 | 2021-05-19 | NGM Biopharmaceuticals, Inc. | Angptl8 polypeptide and its use for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) * | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| EP3411392B1 (en) * | 2016-02-04 | 2021-12-29 | Regeneron Pharmaceuticals, Inc. | Non-human animals having an engineered angptl8 gene |
| MX2018010401A (es) | 2016-03-03 | 2019-03-06 | Regeneron Pharma | Metodos para el tratamiento de pacientes con hiperlipidemia administrando un inhibidor de pcsk9 en combinacion con un inhibidor de angptl3. |
| EP3436049B1 (en) * | 2016-03-31 | 2022-01-12 | Baylor Research Institute | Angiopoietin-like protein 8 (angptl8) |
| PL3439689T3 (pl) * | 2016-04-08 | 2022-01-31 | Regeneron Pharmaceuticals, Inc. | Sposoby leczenia hiperlipidemii inhibitorem angptl8 i inhibitorem angptl3 |
| MX382035B (es) | 2016-11-17 | 2025-03-13 | Regeneron Pharma | Uso de un inhibidor angptl8 en la preparación de un medicamento para tratar la obesidad. |
| EP3749691A4 (en) | 2017-11-10 | 2021-10-27 | NGM Biopharmaceuticals, Inc. | ANGPTL8 LIAISON AGENTS AND THEIR METHODS OF USE |
| WO2019126194A1 (en) | 2017-12-18 | 2019-06-27 | Regeneron Pharmaceuticals, Inc. | Angptl8 assay and uses thereof |
| TWI747098B (zh) * | 2018-12-21 | 2021-11-21 | 美商美國禮來大藥廠 | 抗angptl3/8複合物抗體及其使用方法 |
| US12559551B2 (en) | 2019-05-24 | 2026-02-24 | Regeneron Pharmaceuticals, Inc. | Stabilized formulations containing anti-ANGPTL3 antibodies |
| CN110694068A (zh) * | 2019-11-06 | 2020-01-17 | 北京市心肺血管疾病研究所 | 一种抑制血管生成素样蛋白8的物质的应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US20050100991A1 (en) * | 2001-04-12 | 2005-05-12 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| PT1463751E (pt) | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Proteínas de fusão de albumina |
| WO2011084714A2 (en) | 2009-12-17 | 2011-07-14 | Biogen Idec Ma Inc. | STABILIZED ANTI-TNF-ALPHA scFv MOLECULES OR ANTI-TWEAK scFv MOLECULES AND USES THEREOF |
| CN104039357A (zh) | 2011-06-10 | 2014-09-10 | 哈佛学院校长同事会 | 胰腺β-细胞增殖的调节 |
| CN105073781A (zh) | 2013-01-11 | 2015-11-18 | 加州生物医学研究所 | 牛融合抗体 |
| ES2764833T3 (es) | 2013-10-11 | 2020-06-04 | The United States Of America Represented By The Sec Dep Of Health And Human Services | Anticuerpos contra TEM8 y su uso |
| EP3822287A1 (en) | 2014-10-03 | 2021-05-19 | NGM Biopharmaceuticals, Inc. | Angptl8 polypeptide and its use for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| MX382035B (es) | 2016-11-17 | 2025-03-13 | Regeneron Pharma | Uso de un inhibidor angptl8 en la preparación de un medicamento para tratar la obesidad. |
| EP3749691A4 (en) | 2017-11-10 | 2021-10-27 | NGM Biopharmaceuticals, Inc. | ANGPTL8 LIAISON AGENTS AND THEIR METHODS OF USE |
-
2015
- 2015-10-02 EP EP20185093.0A patent/EP3822287A1/en not_active Withdrawn
- 2015-10-02 AU AU2015327900A patent/AU2015327900B2/en not_active Ceased
- 2015-10-02 WO PCT/US2015/053700 patent/WO2016054494A1/en not_active Ceased
- 2015-10-02 CA CA2954082A patent/CA2954082A1/en active Pending
- 2015-10-02 JP JP2017500335A patent/JP6680758B2/ja not_active Expired - Fee Related
- 2015-10-02 US US15/318,937 patent/US10071139B2/en active Active
- 2015-10-02 ES ES15848061T patent/ES2819866T3/es active Active
- 2015-10-02 EP EP15848061.6A patent/EP3201225B1/en active Active
-
2018
- 2018-08-06 US US16/056,068 patent/US10702587B2/en not_active Expired - Fee Related
-
2020
- 2020-05-29 US US16/888,249 patent/US20210015902A1/en not_active Abandoned
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