JP2017531039A5 - - Google Patents
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- Publication number
- JP2017531039A5 JP2017531039A5 JP2017538467A JP2017538467A JP2017531039A5 JP 2017531039 A5 JP2017531039 A5 JP 2017531039A5 JP 2017538467 A JP2017538467 A JP 2017538467A JP 2017538467 A JP2017538467 A JP 2017538467A JP 2017531039 A5 JP2017531039 A5 JP 2017531039A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- thieno
- azaspiro
- oxa
- carboxamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 *c(cc1*)cc(*)c1NC(c1cc(CCN(C(*2)C2c(cc2)ccc2NC(c(c(N(C2)CC22CCOCC2)n2)cc(*)c2I)=O)c2c-3cccc2)c-3[s]1)=O Chemical compound *c(cc1*)cc(*)c1NC(c1cc(CCN(C(*2)C2c(cc2)ccc2NC(c(c(N(C2)CC22CCOCC2)n2)cc(*)c2I)=O)c2c-3cccc2)c-3[s]1)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14188494 | 2014-10-10 | ||
| EP14188494.0 | 2014-10-10 | ||
| PCT/GB2015/052945 WO2016055792A1 (en) | 2014-10-10 | 2015-10-08 | Novel 5,6-dihydro-4h-benzo[b]thieno-[2,3-d]azepine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017531039A JP2017531039A (ja) | 2017-10-19 |
| JP2017531039A5 true JP2017531039A5 (en:Method) | 2018-11-22 |
Family
ID=51842340
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538467A Withdrawn JP2017531039A (ja) | 2014-10-10 | 2015-10-08 | 新規５，６−ジヒドロ−４Ｈ−ベンゾ［ｂ］チエノ−［２，３−ｄ］アゼピン誘導体 |
| JP2017538466A Active JP6675407B2 (ja) | 2014-10-10 | 2015-10-08 | 新規５，６−ジヒドロ−４Ｈ−ベンゾ［ｂ］チエノ−［２，３−ｄ］アゼピン誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538466A Active JP6675407B2 (ja) | 2014-10-10 | 2015-10-08 | 新規５，６−ジヒドロ−４Ｈ−ベンゾ［ｂ］チエノ−［２，３−ｄ］アゼピン誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US10189863B2 (en:Method) |
| EP (2) | EP3204389B1 (en:Method) |
| JP (2) | JP2017531039A (en:Method) |
| KR (1) | KR20170058921A (en:Method) |
| CN (1) | CN106852144B (en:Method) |
| AU (1) | AU2015329789B2 (en:Method) |
| BR (1) | BR112017005104B1 (en:Method) |
| CA (1) | CA2957868C (en:Method) |
| EA (1) | EA201790796A8 (en:Method) |
| IL (1) | IL250823A0 (en:Method) |
| MX (1) | MX2017004652A (en:Method) |
| SG (1) | SG11201701184WA (en:Method) |
| WO (2) | WO2016055791A1 (en:Method) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106852144B (zh) * | 2014-10-10 | 2019-08-30 | 普尔莫赛德有限公司 | 5,6-二氢-4H-苯并[b]噻吩并-[2,3-d]氮杂*衍生物 |
| US10160772B2 (en) | 2014-12-18 | 2018-12-25 | Pulmocide Limited | 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivatives |
| CN108200760B (zh) | 2015-07-22 | 2022-04-01 | 英安塔制药有限公司 | 作为rsv抑制剂的苯并二氮杂䓬衍生物 |
| EP3402799B1 (en) | 2016-01-15 | 2022-05-04 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as rsv inhibitors |
| EA202092250A1 (ru) * | 2016-02-03 | 2020-12-11 | Янссен Сайенсиз Айрлэнд Юси | Комбинированные продукты для лечения rsv |
| WO2017175000A1 (en) * | 2016-04-08 | 2017-10-12 | Pulmocide Limited | Compounds |
| US10398706B2 (en) | 2017-01-06 | 2019-09-03 | Enanta Pharmaceuticals, Inc. | Heteroaryldiazepine derivatives as RSV inhibitors |
| ES2923521T3 (es) | 2017-02-16 | 2022-09-28 | Enanta Pharm Inc | Procesos para la preparación de derivados de benzodiazepina |
| WO2018226801A1 (en) | 2017-06-07 | 2018-12-13 | Enanta Pharmaceuticals, Inc. | Aryldiazepine derivatives as rsv inhibitors |
| US11091501B2 (en) | 2017-06-30 | 2021-08-17 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| WO2019006291A1 (en) * | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| JP7198811B2 (ja) | 2017-09-29 | 2023-01-04 | エナンタ ファーマシューティカルズ インコーポレイテッド | Ｒｓｖ阻害剤としての組み合わせ医薬剤 |
| WO2019094920A1 (en) | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Azepin-2-one derivatives as rsv inhibitors |
| CA3080138A1 (en) | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives |
| WO2019199908A1 (en) * | 2018-04-11 | 2019-10-17 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as rsv inhibitors |
| CN113710276B (zh) | 2019-03-18 | 2024-03-29 | 英安塔制药有限公司 | 苯二氮䓬衍生物作为rsv抑制剂 |
| US11179400B2 (en) | 2019-04-09 | 2021-11-23 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| TWI864048B (zh) | 2019-10-04 | 2024-12-01 | 美商安塔製藥公司 | 抗病毒雜環化合物、其醫藥組成物及其用途 |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| WO2022010882A1 (en) * | 2020-07-07 | 2022-01-13 | Enanta Pharmaceuticals, Inc, | Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors |
| US11945824B2 (en) | 2020-10-19 | 2024-04-02 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| UY39642A (es) | 2021-02-26 | 2022-09-30 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| AR129003A1 (es) | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| US12162857B2 (en) | 2022-04-27 | 2024-12-10 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693635A (en) | 1993-07-29 | 1997-12-02 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| AU782404B2 (en) | 1999-04-28 | 2005-07-28 | Sanofi-Aventis Deutschland Gmbh | Tri-aryl acid derivatives as PPAR receptor ligands |
| AU2009204147A1 (en) * | 2008-01-07 | 2009-07-16 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| US8999969B2 (en) | 2009-07-09 | 2015-04-07 | Gilead Sciences, Inc. | Anti-RSV compounds |
| US9144557B2 (en) | 2009-10-13 | 2015-09-29 | Ligand Pharmaceuticals Inc. | Hematopoietic growth factor mimetic small molecule compounds and their uses |
| EA025611B1 (ru) | 2010-07-29 | 2017-01-30 | Райджел Фармасьютикалз, Инк. | Активирующие ampk гетероциклические соединения и способы их использования |
| WO2012129562A2 (en) | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| MX2017001587A (es) | 2014-08-05 | 2017-10-11 | Alios Biopharma Inc | Terapia de combinacion para tratar un paramixovirus. |
| CN106852144B (zh) | 2014-10-10 | 2019-08-30 | 普尔莫赛德有限公司 | 5,6-二氢-4H-苯并[b]噻吩并-[2,3-d]氮杂*衍生物 |
| EP3402799B1 (en) | 2016-01-15 | 2022-05-04 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as rsv inhibitors |
| EA202092250A1 (ru) | 2016-02-03 | 2020-12-11 | Янссен Сайенсиз Айрлэнд Юси | Комбинированные продукты для лечения rsv |
| US11091501B2 (en) | 2017-06-30 | 2021-08-17 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| WO2019006291A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
-
2015
- 2015-10-08 CN CN201580054496.3A patent/CN106852144B/zh active Active
- 2015-10-08 WO PCT/GB2015/052944 patent/WO2016055791A1/en not_active Ceased
- 2015-10-08 WO PCT/GB2015/052945 patent/WO2016055792A1/en not_active Ceased
- 2015-10-08 MX MX2017004652A patent/MX2017004652A/es unknown
- 2015-10-08 JP JP2017538467A patent/JP2017531039A/ja not_active Withdrawn
- 2015-10-08 SG SG11201701184WA patent/SG11201701184WA/en unknown
- 2015-10-08 BR BR112017005104-4A patent/BR112017005104B1/pt active IP Right Grant
- 2015-10-08 EA EA201790796A patent/EA201790796A8/ru unknown
- 2015-10-08 KR KR1020177006394A patent/KR20170058921A/ko not_active Withdrawn
- 2015-10-08 AU AU2015329789A patent/AU2015329789B2/en active Active
- 2015-10-08 US US15/516,809 patent/US10189863B2/en active Active
- 2015-10-08 EP EP15784440.8A patent/EP3204389B1/en active Active
- 2015-10-08 CA CA2957868A patent/CA2957868C/en active Active
- 2015-10-08 US US15/305,003 patent/US9732098B2/en active Active
- 2015-10-08 JP JP2017538466A patent/JP6675407B2/ja active Active
- 2015-10-08 EP EP15782045.7A patent/EP3204388B1/en active Active
-
2017
- 2017-02-27 IL IL250823A patent/IL250823A0/en active IP Right Grant
- 2017-07-06 US US15/642,637 patent/US9926335B2/en active Active
-
2018
- 2018-02-22 US US15/902,077 patent/US10035810B2/en active Active
- 2018-07-12 US US16/033,464 patent/US10273249B2/en active Active
-
2019
- 2019-03-11 US US16/298,460 patent/US10472375B2/en active Active
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