JP2017530982A5 - - Google Patents

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Publication number
JP2017530982A5
JP2017530982A5 JP2017518329A JP2017518329A JP2017530982A5 JP 2017530982 A5 JP2017530982 A5 JP 2017530982A5 JP 2017518329 A JP2017518329 A JP 2017518329A JP 2017518329 A JP2017518329 A JP 2017518329A JP 2017530982 A5 JP2017530982 A5 JP 2017530982A5
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JP
Japan
Prior art keywords
composition according
subject
compound
disorder
sterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2017518329A
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English (en)
Japanese (ja)
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JP2017530982A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/054551 external-priority patent/WO2016057713A1/en
Publication of JP2017530982A publication Critical patent/JP2017530982A/ja
Publication of JP2017530982A5 publication Critical patent/JP2017530982A5/ja
Withdrawn legal-status Critical Current

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JP2017518329A 2014-10-07 2015-10-07 神経刺激性化合物およびその使用方法 Withdrawn JP2017530982A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462060932P 2014-10-07 2014-10-07
US62/060,932 2014-10-07
PCT/US2015/054551 WO2016057713A1 (en) 2014-10-07 2015-10-07 Neuroactive compounds and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020149725A Division JP2020196759A (ja) 2014-10-07 2020-09-07 神経刺激性化合物およびその使用方法

Publications (2)

Publication Number Publication Date
JP2017530982A JP2017530982A (ja) 2017-10-19
JP2017530982A5 true JP2017530982A5 (enExample) 2018-11-15

Family

ID=55653736

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017518329A Withdrawn JP2017530982A (ja) 2014-10-07 2015-10-07 神経刺激性化合物およびその使用方法
JP2020149725A Withdrawn JP2020196759A (ja) 2014-10-07 2020-09-07 神経刺激性化合物およびその使用方法
JP2022000454A Pending JP2022033285A (ja) 2014-10-07 2022-01-05 神経刺激性化合物およびその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2020149725A Withdrawn JP2020196759A (ja) 2014-10-07 2020-09-07 神経刺激性化合物およびその使用方法
JP2022000454A Pending JP2022033285A (ja) 2014-10-07 2022-01-05 神経刺激性化合物およびその使用方法

Country Status (17)

Country Link
US (2) US20170304321A1 (enExample)
EP (1) EP3204011A4 (enExample)
JP (3) JP2017530982A (enExample)
KR (1) KR20170065637A (enExample)
CN (2) CN107405352A (enExample)
AU (2) AU2015330906A1 (enExample)
BR (1) BR112017007053A2 (enExample)
CA (1) CA2963938C (enExample)
IL (2) IL292465B2 (enExample)
MX (2) MX388694B (enExample)
MY (1) MY202135A (enExample)
PE (1) PE20170907A1 (enExample)
PH (1) PH12017500639A1 (enExample)
RU (1) RU2764702C2 (enExample)
SG (2) SG10202011773UA (enExample)
WO (1) WO2016057713A1 (enExample)
ZA (1) ZA201702545B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE062616T2 (hu) 2011-09-08 2023-11-28 Sage Therapeutics Inc Neuroaktív szteroidok, készítmények és alkalmazásaik
FI3932932T3 (fi) 2013-03-13 2025-10-15 Sage Therapeutics Inc Neuroaktiivisia steroideja ja niiden käyttömenetelmiä
JP6426694B2 (ja) 2013-03-15 2018-11-21 グローバル ブラッド セラピューティクス インコーポレイテッド ヘモグロビンの修飾のための化合物及びその使用
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
EA201990684A1 (ru) 2013-12-24 2020-12-30 Вирджиния Коммонвелт Юниверсити Способы применения оксигенированных холестеролсульфатов (ocs)
JP6628745B2 (ja) 2014-06-18 2020-01-15 セージ セラピューティクス, インコーポレイテッド オキシステロールおよびその使用方法
PT3319611T (pt) 2015-07-06 2021-04-22 Sage Therapeutics Inc Oxisteróis e métodos de utilização dos mesmos
WO2017007832A1 (en) * 2015-07-06 2017-01-12 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
DK3812392T3 (da) 2015-07-06 2025-07-21 Sage Therapeutics Inc Oxysteroler og fremgangsmåder til anvendelse deraf
ES2921010T3 (es) 2016-04-01 2022-08-16 Sage Therapeutics Inc Oxisteroles y procedimientos de uso de los mismos
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
WO2018009867A1 (en) 2016-07-07 2018-01-11 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
IL298681A (en) * 2016-08-02 2023-01-01 Univ Virginia Commonwealth Preparations
MA46351A (fr) 2016-09-30 2021-06-02 Sage Therapeutics Inc Oxystérols substitués en c7 et procédés en tant que modulateurs nmda
KR102521573B1 (ko) 2016-10-18 2023-04-14 세이지 테라퓨틱스, 인크. 옥시스테롤 및 그의 사용 방법
DK3529257T3 (da) * 2016-10-18 2023-08-07 Sage Therapeutics Inc Oxysteroler og fremgangsmåder til anvendelse deraf
EP3335730A1 (en) * 2016-12-15 2018-06-20 Fundació Institut de Recerca Biomédica de Bellvitge (IDIBELL) Compounds for treating x-linked adrenoleukodystrophy
US10857163B1 (en) 2019-09-30 2020-12-08 Athenen Therapeutics, Inc. Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof
CN115103591B (zh) 2019-12-27 2026-06-19 度勒科特公司 结晶性和液体结晶性25-羟基-胆甾-5-烯-3-硫酸钠及其制备方法
CN116490507A (zh) 2020-09-10 2023-07-25 薛定谔公司 用于治疗癌症的杂环包缩合cdc7激酶抑制剂
WO2026102175A1 (en) * 2024-11-06 2026-05-15 Sage Therapeutics, LLC Nmda receptor-modulatory compounds and methods of use thereof

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
WO2006037016A2 (en) * 2004-09-27 2006-04-06 The Regents Of The University Of California Novel therapy for treatment of chronic degenerative brain diseases and nervous system injury
GB0712494D0 (en) * 2007-06-27 2007-08-08 Isis Innovation Substrate reduction therapy
US20110118353A1 (en) * 2007-11-06 2011-05-19 N. V. Organon Method of hormone suppression in humans
WO2009137843A2 (en) * 2008-05-09 2009-11-12 Emory University Nmda receptor antagonists for the treatment of neuropsychiatric disorders
WO2010065709A2 (en) * 2008-12-03 2010-06-10 Amin Khan Hydroxamic acid derivatives, preparation and therapeutic uses thereof
US20110319416A1 (en) * 2009-01-28 2011-12-29 Emory University Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions
WO2011028794A2 (en) * 2009-09-01 2011-03-10 Lazarus Therapeutics, Inc. Treatment of huntington's disease with cycloserine and an nmda receptor antagonist
KR101692275B1 (ko) * 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 2차 구조 안정화된 nmda 수용체 조절제 및 그의 용도
US20120035156A1 (en) * 2010-08-09 2012-02-09 Daniela Alberati Combination of glyt1 compound with antipsychotics
HUE062616T2 (hu) * 2011-09-08 2023-11-28 Sage Therapeutics Inc Neuroaktív szteroidok, készítmények és alkalmazásaik
US20150119327A1 (en) * 2012-04-25 2015-04-30 The Regents Of The University Of California Drug screening platform for rett syndrome
US9737522B2 (en) * 2012-08-09 2017-08-22 Emory University NMDA receptor modulators and uses related thereto
JP6419087B2 (ja) * 2013-01-29 2018-11-07 アプティニックス インコーポレイテッド スピロラクタム系nmda受容体モジュレーターおよびその使用
FI3932932T3 (fi) 2013-03-13 2025-10-15 Sage Therapeutics Inc Neuroaktiivisia steroideja ja niiden käyttömenetelmiä
CN112057457A (zh) * 2013-03-13 2020-12-11 萨奇治疗股份有限公司 神经活性类固醇、组合物、及其用途
JP6628745B2 (ja) * 2014-06-18 2020-01-15 セージ セラピューティクス, インコーポレイテッド オキシステロールおよびその使用方法
EP3166613A4 (en) * 2014-07-09 2018-02-21 Duke University Compositions and methods for the repair of myelin
WO2017007832A1 (en) * 2015-07-06 2017-01-12 Sage Therapeutics, Inc. Oxysterols and methods of use thereof

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