JP2017530372A5 - - Google Patents

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Publication number
JP2017530372A5
JP2017530372A5 JP2017533704A JP2017533704A JP2017530372A5 JP 2017530372 A5 JP2017530372 A5 JP 2017530372A5 JP 2017533704 A JP2017533704 A JP 2017533704A JP 2017533704 A JP2017533704 A JP 2017533704A JP 2017530372 A5 JP2017530372 A5 JP 2017530372A5
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JP
Japan
Prior art keywords
vegf
pharmaceutical composition
patient
domain
antagonist
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JP2017533704A
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English (en)
Japanese (ja)
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JP2017530372A (ja
JP6692358B2 (ja
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Priority claimed from PCT/US2015/049279 external-priority patent/WO2016044041A1/en
Publication of JP2017530372A publication Critical patent/JP2017530372A/ja
Publication of JP2017530372A5 publication Critical patent/JP2017530372A5/ja
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Publication of JP6692358B2 publication Critical patent/JP6692358B2/ja
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JP2017533704A 2014-09-16 2015-09-10 転移性結腸直腸癌の抗血管新生療法に関連する予測的及び予後的バイオマーカー Active JP6692358B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462051091P 2014-09-16 2014-09-16
US62/051,091 2014-09-16
US201562099630P 2015-01-05 2015-01-05
US62/099,630 2015-01-05
PCT/US2015/049279 WO2016044041A1 (en) 2014-09-16 2015-09-10 Predictive and prognostic biomarkers related to anti-angiogenic therapy of metastatic colorectal cancer

Publications (3)

Publication Number Publication Date
JP2017530372A JP2017530372A (ja) 2017-10-12
JP2017530372A5 true JP2017530372A5 (enExample) 2018-10-11
JP6692358B2 JP6692358B2 (ja) 2020-05-13

Family

ID=54207741

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017533704A Active JP6692358B2 (ja) 2014-09-16 2015-09-10 転移性結腸直腸癌の抗血管新生療法に関連する予測的及び予後的バイオマーカー

Country Status (12)

Country Link
US (2) US10525104B2 (enExample)
EP (1) EP3194974B1 (enExample)
JP (1) JP6692358B2 (enExample)
KR (1) KR102471057B1 (enExample)
CN (1) CN107076749B (enExample)
AU (1) AU2015318207B2 (enExample)
CA (1) CA2960890A1 (enExample)
EA (1) EA036671B1 (enExample)
IL (1) IL250905B (enExample)
MX (1) MX382673B (enExample)
WO (1) WO2016044041A1 (enExample)
ZA (1) ZA201701664B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2971054A4 (en) 2013-03-14 2017-04-12 Otraces Inc. A method for improving disease diagnosis using measured analytes
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
EP3405896A4 (en) 2016-01-22 2019-09-25 Otraces Inc. SYSTEMS AND METHOD FOR IMPROVED DIAGNOSIS OF ILLNESSES
CN117347612A (zh) 2017-03-31 2024-01-05 广津生物科学株式会社 癌患者的治疗效果的预测和/或复发监测
US11524053B2 (en) 2018-01-26 2022-12-13 The Regents Of The University Of California Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents
US12071476B2 (en) 2018-03-02 2024-08-27 Kodiak Sciences Inc. IL-6 antibodies and fusion constructs and conjugates thereof
WO2020165483A1 (es) * 2019-02-15 2020-08-20 Universidad de Córdoba Método de predicción de respuesta a tratamiento del cáncer con agentes antiangiogénicos
WO2021011491A1 (en) * 2019-07-13 2021-01-21 Otraces Inc. Improving diagnosis for various diseases using tumor microenvironment active proteins
AU2020364071A1 (en) 2019-10-10 2022-05-26 Kodiak Sciences Inc. Methods of treating an eye disorder
WO2021076852A1 (en) * 2019-10-17 2021-04-22 Board Of Regents, The University Of Texas System Small extracellular vesicle-associated vegf as a predictor for therapeutic responses
AU2020393842A1 (en) 2019-11-25 2022-06-16 The Regents Of The University Of California Long-acting VEGF inhibitors for intraocular neovascularization

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7396664B2 (en) 1999-06-08 2008-07-08 Regeneron Pharmaceuticals, Inc. VEGF-binding fusion proteins and nucleic acids encoding the same
US7070959B1 (en) 1999-06-08 2006-07-04 Regeneron Pharmaceuticals, Inc. Modified chimeric polypeptides with improved pharmacokinetic properties
CN101283280A (zh) * 2005-08-18 2008-10-08 Zadec私人有限公司 用于诊断结直肠癌的蛋白质标记和所述标记作为所述癌症类型治疗的药物靶点的用途
WO2011020115A2 (en) * 2009-08-14 2011-02-17 Allergan, Inc. Methods of treating cancer using growth factor retargeted endopeptidases
AU2011208805A1 (en) 2010-01-19 2012-06-21 F. Hoffman-La Roche Ag Tumor tissue based biomarkers for bevacizumab combination therapies
EP2596359A1 (en) 2010-07-19 2013-05-29 F.Hoffmann-La Roche Ag Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)

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