JP2017529851A - 養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター - Google Patents

養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター Download PDF

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JP2017529851A
JP2017529851A JP2017516350A JP2017516350A JP2017529851A JP 2017529851 A JP2017529851 A JP 2017529851A JP 2017516350 A JP2017516350 A JP 2017516350A JP 2017516350 A JP2017516350 A JP 2017516350A JP 2017529851 A JP2017529851 A JP 2017529851A
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cell
cells
seq
gpc3
car
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JP2017529851A5 (cg-RX-API-DMAC7.html
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ヘクジー、アンドラス
ゴットシャルク、ステファン、エム．ジー．
メテリツァ、レオニド、エス．
ドッティ、ジャンピエトロ
リー、ウェンポン
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Baylor College of Medicine
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JP2017516350A 2014-09-26 2015-09-25 養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター Pending JP2017529851A (ja)

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US201462055979P 2014-09-26 2014-09-26
US62/055,979 2014-09-26
PCT/US2015/052227 WO2016049459A1 (en) 2014-09-26 2015-09-25 Glypican-3 specific chimeric antigen receptors for adoptive immunotherapy

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JP2017529851A true JP2017529851A (ja) 2017-10-12
JP2017529851A5 JP2017529851A5 (cg-RX-API-DMAC7.html) 2018-11-08

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EP (2) EP3198010B1 (cg-RX-API-DMAC7.html)
JP (1) JP2017529851A (cg-RX-API-DMAC7.html)
DE (1) DE20196219T1 (cg-RX-API-DMAC7.html)
ES (2) ES2851123T1 (cg-RX-API-DMAC7.html)
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WO2021186395A1 (en) * 2020-03-18 2021-09-23 Eutilex Co., Ltd. Gpc3 car- t cells secreting il-18 and methods of making and using the same
WO2021186397A1 (en) * 2020-03-18 2021-09-23 Eutilex Co., Ltd. Gpc3 car-t cell compositions and methods of making and using the same
JP2021534740A (ja) * 2018-08-14 2021-12-16 ソティオ，リミティド ライアビリティ カンパニー クレブス回路を調節するトランス代謝分子と組み合わせたキメラ抗原受容体ポリペプチド、及び、それらの治療的使用
JP2023549939A (ja) * 2020-12-14 2023-11-29 北京基因▲啓▼明生物科技有限公司 高い増幅、生存能力及び殺腫瘍作用を有するＣＡＲ－ｉＮＫＴ及びその使用
JP2024045239A (ja) * 2018-12-19 2024-04-02 インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） キメラ抗原受容体を発現する粘膜関連インバリアントｔ（ｍａｉｔ）細胞

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US20190262397A1 (en) 2016-07-26 2019-08-29 Tessa Therapeutics Pte. Ltd. Chimeric antigen receptor
IL266892B2 (en) 2016-12-02 2025-10-01 Univ Southern California Artificial immune receptors and methods of using them
JP2018093823A (ja) * 2016-12-15 2018-06-21 Ｈｅａｒｔｓｅｅｄ株式会社 未分化幹細胞除去剤及び未分化幹細胞除去方法
CA3049189A1 (en) * 2017-01-10 2018-07-19 Yamaguchi University Anti-gpc3 antibody
SG11201909728XA (en) 2017-04-26 2019-11-28 Eureka Therapeutics Inc Constructs specifically recognizing glypican 3 and uses thereof
EP3441461A1 (en) * 2017-08-11 2019-02-13 Baylor College of Medicine Cd1d-restricted nkt cells as a platform for off-the-shelf cancer immunotherapy
EP3806888B1 (en) 2018-06-12 2024-01-31 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
WO2019246563A1 (en) 2018-06-22 2019-12-26 Kite Pharma, Inc. Chimeric transmembrane proteins and uses thereof
US20210261646A1 (en) * 2018-07-03 2021-08-26 Sotio, LLC Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
US20230071098A1 (en) * 2018-07-17 2023-03-09 Noile-Immune Biotech, Inc. Anti-gpc3 single-chain antibody-containing car
AU2019354395A1 (en) 2018-10-01 2021-05-06 Adicet Therapeutics, Inc. Compositions and methods regarding engineered and non-engineered γδ -T cells for treatment of solid tumors
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EP3876950A4 (en) * 2018-11-07 2022-11-30 SOTIO Biotech Inc. CHIMERIC ANTI-GPC3 ANTIGEN RECEPTORS (CARS) IN COMBINATION WITH TRANS-CO-STIMULATORY MOLECULES AND THEIR THERAPEUTIC USES
US12227551B2 (en) 2018-12-11 2025-02-18 Obsidian Therapeutics, Inc. Membrane bound IL12 compositions and methods for tunable regulation
CA3132840A1 (en) 2019-03-08 2020-09-17 Obsidian Therapeutics, Inc. Human carbonic anhydrase 2 compositions and methods for tunable regulation
US20220195397A1 (en) * 2019-04-04 2022-06-23 Shanghai Pharmaceuticals Holding Co., Ltd. Immune cell containing tumor antigen recognition receptor and application thereof
WO2020252404A1 (en) 2019-06-12 2020-12-17 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
CN114450308A (zh) 2019-06-12 2022-05-06 黑曜石疗法公司 用于调节性调控的ca2组合物和方法
WO2020257823A2 (en) 2019-06-21 2020-12-24 Kite Pharma, Inc. TGF-β RECEPTORS AND METHODS OF USE
US20220348937A1 (en) 2019-09-06 2022-11-03 Obsidian Therapeutics, Inc. Compositions and methods for dhfr tunable protein regulation
WO2022016119A1 (en) 2020-07-17 2022-01-20 Simurx, Inc. Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
JP2024500847A (ja) 2020-12-18 2024-01-10 センチュリー セラピューティクス，インコーポレイテッド 適合可能な受容体特異性を有するキメラ抗原受容体システム
US20240181055A1 (en) 2021-04-08 2024-06-06 Crage Medical Co., Limited Cellular immunotherapy use
CN118488969A (zh) 2021-11-16 2024-08-13 舒迪安生物技术公司 粘液样/圆形细胞脂肪肉瘤患者的治疗
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WO2013040371A2 (en) * 2011-09-16 2013-03-21 Baylor College Of Medicine Targeting the tumor microenvironment using manipulated nkt cells
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JP7778081B2 (ja) 2020-03-18 2025-12-01 ユーティレックス カンパニー リミテッド Ｉｌ－１８を分泌するｇｐｃ３ ｃａｒ－ｔ細胞、並びにそれを作製する方法及び使用する方法
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