JP2017529837A - 細胞結合剤及び細胞毒性剤を含む複合体 - Google Patents

細胞結合剤及び細胞毒性剤を含む複合体 Download PDF

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JP2017529837A
JP2017529837A JP2017512760A JP2017512760A JP2017529837A JP 2017529837 A JP2017529837 A JP 2017529837A JP 2017512760 A JP2017512760 A JP 2017512760A JP 2017512760 A JP2017512760 A JP 2017512760A JP 2017529837 A JP2017529837 A JP 2017529837A
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ala
antibody
complex
optionally substituted
antigen
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JP2017529837A5 (enExample
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ハリス,ルーク・ビー
タバーレス,ダニエル
ルイ,リンギュン
フィシュキン,ネイサン・エリオット
シズカ,マナミ
ミラー,マイケル・ルイス
チャリ,ラビ・ヴイ・ジェイ
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イミュノジェン・インコーポレーテッド
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JP2017512760A 2014-09-03 2015-09-02 細胞結合剤及び細胞毒性剤を含む複合体 Pending JP2017529837A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462045264P 2014-09-03 2014-09-03
US62/045,264 2014-09-03
US201462086986P 2014-12-03 2014-12-03
US62/086,986 2014-12-03
US201562149379P 2015-04-17 2015-04-17
US62/149,379 2015-04-17
US201562186235P 2015-06-29 2015-06-29
US62/186,235 2015-06-29
PCT/US2015/048044 WO2016036794A1 (en) 2014-09-03 2015-09-02 Conjugates comprising cell-binding agents and cytotoxic agents

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JP2017529837A true JP2017529837A (ja) 2017-10-12
JP2017529837A5 JP2017529837A5 (enExample) 2018-10-11

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US (3) US10988531B2 (enExample)
EP (1) EP3188733B1 (enExample)
JP (1) JP2017529837A (enExample)
KR (3) KR20240027148A (enExample)
CN (1) CN107580604A (enExample)
AU (1) AU2015312075A1 (enExample)
CA (1) CA2957964A1 (enExample)
IL (1) IL250711A0 (enExample)
MA (1) MA40415A (enExample)
RU (1) RU2017110068A (enExample)
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Cited By (3)

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JP2017527563A (ja) * 2014-09-03 2017-09-21 イミュノジェン・インコーポレーテッド 細胞障害性ベンゾジアゼピン誘導体
JP2019511462A (ja) * 2016-02-05 2019-04-25 ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. Gcc標的化抗体−薬物コンジュゲート
JP2021510694A (ja) * 2018-01-12 2021-04-30 イミュノジェン, インコーポレイテッド 抗体薬物のコンジュゲーション、精製、及び製剤のための方法

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AU2015311951B2 (en) * 2014-09-02 2021-04-08 Immunogen, Inc. Methods for formulating antibody drug conjugate compositions
TW201609152A (zh) 2014-09-03 2016-03-16 免疫原公司 包含細胞結合劑及細胞毒性劑之偶聯物
CA2976005A1 (en) 2015-02-06 2016-08-11 Cell Idx, Inc. Antigen-coupled immunoreagents
SMT202100092T1 (it) 2015-06-29 2021-03-15 Immunogen Inc Anticorpi anti-cd123 e loro coniugati e derivati
SMT202000004T1 (it) * 2015-07-21 2020-03-13 Immunogen Inc Metodi di preparazione dei derivati citotossici di benzodiazepina
WO2018006785A1 (zh) * 2016-07-05 2018-01-11 江苏恒瑞医药股份有限公司 Egfr抗体-药物偶联物及其在医药上的应用
WO2018017923A1 (en) 2016-07-22 2018-01-25 Nektar Therapeutics Conjugates of a factor viii moiety having an oxime-containing linkage
RU2019114863A (ru) * 2016-11-02 2020-12-03 Иммуноджен, Инк. Комбинированное лечение конъюгатами антитело-лекарственное средство и ингибиторами parp
JP7350313B2 (ja) 2016-12-16 2023-09-26 ブルーフィン バイオメディシン, インコーポレイテッド 抗cubドメイン含有タンパク質1(cdcp1)抗体、抗体薬物コンジュゲート、およびその使用方法
SI3558391T1 (sl) * 2016-12-23 2022-06-30 Immunogen, Inc. Imunokonjugati, ciljno usmerjeni na ADAM9, in načini njihove uporabe
CN116785450A (zh) * 2017-02-28 2023-09-22 伊缪诺金公司 具有自分解肽接头的类美登素衍生物和其缀合物
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