JP2017529837A - 細胞結合剤及び細胞毒性剤を含む複合体 - Google Patents

細胞結合剤及び細胞毒性剤を含む複合体 Download PDF

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JP2017529837A
JP2017529837A JP2017512760A JP2017512760A JP2017529837A JP 2017529837 A JP2017529837 A JP 2017529837A JP 2017512760 A JP2017512760 A JP 2017512760A JP 2017512760 A JP2017512760 A JP 2017512760A JP 2017529837 A JP2017529837 A JP 2017529837A
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ala
antibody
complex
optionally substituted
antigen
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JP2017529837A5 (enExample
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ハリス，ルーク・ビー
タバーレス，ダニエル
ルイ，リンギュン
フィシュキン，ネイサン・エリオット
シズカ，マナミ
ミラー，マイケル・ルイス
チャリ，ラビ・ヴイ・ジェイ
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イミュノジェン・インコーポレーテッド
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  • Health & Medical Sciences (AREA)
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  • Pain & Pain Management (AREA)
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  • Virology (AREA)
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JP2017512760A 2014-09-03 2015-09-02 細胞結合剤及び細胞毒性剤を含む複合体 Pending JP2017529837A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462045264P 2014-09-03 2014-09-03
US62/045,264 2014-09-03
US201462086986P 2014-12-03 2014-12-03
US62/086,986 2014-12-03
US201562149379P 2015-04-17 2015-04-17
US62/149,379 2015-04-17
US201562186235P 2015-06-29 2015-06-29
US62/186,235 2015-06-29
PCT/US2015/048044 WO2016036794A1 (en) 2014-09-03 2015-09-02 Conjugates comprising cell-binding agents and cytotoxic agents

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JP2017529837A true JP2017529837A (ja) 2017-10-12
JP2017529837A5 JP2017529837A5 (enExample) 2018-10-11

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US (3) US10988531B2 (enExample)
EP (1) EP3188733B1 (enExample)
JP (1) JP2017529837A (enExample)
KR (3) KR102508023B1 (enExample)
CN (1) CN107580604A (enExample)
AU (1) AU2015312075A1 (enExample)
CA (1) CA2957964A1 (enExample)
IL (1) IL250711A0 (enExample)
MA (1) MA40415A (enExample)
RU (1) RU2017110068A (enExample)
SG (2) SG11201701565PA (enExample)
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WO (1) WO2016036794A1 (enExample)

Cited By (3)

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JP2017527563A (ja) * 2014-09-03 2017-09-21 イミュノジェン・インコーポレーテッド 細胞障害性ベンゾジアゼピン誘導体
JP2019511462A (ja) * 2016-02-05 2019-04-25 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Ｇｃｃ標的化抗体−薬物コンジュゲート
JP2021510694A (ja) * 2018-01-12 2021-04-30 イミュノジェン， インコーポレイテッド 抗体薬物のコンジュゲーション、精製、及び製剤のための方法

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MA40539A (fr) * 2014-09-02 2016-03-10 Immunogen Inc Procédés de formulation de compositions de conjugués anticorps-médicaments
SG11201701565PA (en) 2014-09-03 2017-03-30 Immunogen Inc Conjugates comprising cell-binding agents and cytotoxic agents
IL282614B2 (en) 2015-02-06 2024-02-01 Cell Idx Inc Antigen-conjugated immune reagents
SMT202100092T1 (it) * 2015-06-29 2021-03-15 Immunogen Inc Anticorpi anti-cd123 e loro coniugati e derivati
EP3778602B1 (en) * 2015-07-21 2023-07-12 ImmunoGen, Inc. Methods of preparing cytotoxic benzodiazepine derivatives
TWI750194B (zh) * 2016-07-05 2021-12-21 大陸商江蘇恆瑞醫藥股份有限公司 Ｅｇｆｒ抗體-藥物偶聯物及其在醫藥上的應用
WO2018017923A1 (en) 2016-07-22 2018-01-25 Nektar Therapeutics Conjugates of a factor viii moiety having an oxime-containing linkage
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