JP2017526767A5 - - Google Patents
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- Publication number
- JP2017526767A5 JP2017526767A5 JP2017501288A JP2017501288A JP2017526767A5 JP 2017526767 A5 JP2017526767 A5 JP 2017526767A5 JP 2017501288 A JP2017501288 A JP 2017501288A JP 2017501288 A JP2017501288 A JP 2017501288A JP 2017526767 A5 JP2017526767 A5 JP 2017526767A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cooh
- cycloalkyl
- substituted
- heteroalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 24
- 125000000217 alkyl group Chemical group 0.000 claims 23
- 150000003973 alkyl amines Chemical class 0.000 claims 22
- 125000004404 heteroalkyl group Chemical group 0.000 claims 22
- 125000001072 heteroaryl group Chemical group 0.000 claims 22
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 21
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 21
- 125000003118 aryl group Chemical group 0.000 claims 18
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims 17
- 150000001408 amides Chemical class 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 15
- 208000015181 infectious disease Diseases 0.000 claims 9
- 206010028116 Mucosal inflammation Diseases 0.000 claims 8
- 201000010927 Mucositis Diseases 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 208000003265 stomatitis Diseases 0.000 claims 8
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 7
- 229910052799 carbon Inorganic materials 0.000 claims 7
- 229920000642 polymer Polymers 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 125000003368 amide group Chemical group 0.000 claims 6
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 5
- 238000011282 treatment Methods 0.000 claims 5
- 125000005915 C6-C14 aryl group Chemical group 0.000 claims 4
- 206010048685 Oral infection Diseases 0.000 claims 4
- 150000001450 anions Chemical class 0.000 claims 4
- 125000001475 halogen functional group Chemical group 0.000 claims 4
- 208000035473 Communicable disease Diseases 0.000 claims 3
- 201000003883 Cystic fibrosis Diseases 0.000 claims 3
- 208000031650 Surgical Wound Infection Diseases 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 230000002685 pulmonary effect Effects 0.000 claims 3
- 208000032376 Lung infection Diseases 0.000 claims 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 238000011321 prophylaxis Methods 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462023330P | 2014-07-11 | 2014-07-11 | |
| US62/023,330 | 2014-07-11 | ||
| PCT/US2015/039881 WO2016007821A2 (en) | 2014-07-11 | 2015-07-10 | Main chain polyamines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017526767A JP2017526767A (ja) | 2017-09-14 |
| JP2017526767A5 true JP2017526767A5 (https=) | 2018-08-09 |
| JP6765363B2 JP6765363B2 (ja) | 2020-10-07 |
Family
ID=53682888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017501288A Expired - Fee Related JP6765363B2 (ja) | 2014-07-11 | 2015-07-10 | 主鎖ポリアミン |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20170182087A1 (https=) |
| EP (1) | EP3189091A2 (https=) |
| JP (1) | JP6765363B2 (https=) |
| KR (1) | KR20170028979A (https=) |
| CN (1) | CN106687504A (https=) |
| AR (1) | AR101184A1 (https=) |
| AU (1) | AU2015287661B2 (https=) |
| BR (1) | BR112017000258A2 (https=) |
| CA (1) | CA2954768A1 (https=) |
| IL (1) | IL249963A0 (https=) |
| MX (1) | MX2017000447A (https=) |
| RU (1) | RU2017104223A (https=) |
| SG (1) | SG11201610886VA (https=) |
| TW (1) | TW201615694A (https=) |
| WO (1) | WO2016007821A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10301254B2 (en) | 2015-04-23 | 2019-05-28 | Temple University—Of the Commonwealth System of Higher Education | Substituted polycationic multi-quaternary ammonium salts as antimicrobial agents |
| US11111216B2 (en) | 2016-10-26 | 2021-09-07 | Temple University-Of The Commonwealth System Of Higher Education | Polycationic amphiphiles as antimicrobial agents and methods using same |
| GB201700404D0 (en) * | 2017-01-10 | 2017-02-22 | Saraswati Res And Dev Inst | Compounds and composistions |
| GB2584074B (en) | 2019-04-16 | 2021-08-11 | Alectrona Pte Ltd | Monoterpene phenol derivatives |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790953A (fr) * | 1971-11-05 | 1973-05-03 | Beecham Group Ltd | Matiere biologiquement active |
| BE793157A (fr) * | 1971-12-21 | 1973-06-21 | Beecham Group Ltd | Substance antivirale |
| IT981412B (it) * | 1973-03-15 | 1974-10-10 | Montedison Spa | Poliammidi da acidi eterociclici aromatici ortocarbossilici e pro cedimento per prepararle |
| US4013507A (en) * | 1973-09-18 | 1977-03-22 | California Institute Of Technology | Ionene polymers for selectively inhibiting the vitro growth of malignant cells |
| USRE38417E1 (en) * | 1986-12-02 | 2004-02-03 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
| CA1305425C (en) * | 1986-12-02 | 1992-07-21 | Raymond J. Bergeron | Anti-neoplastic spermine derivative |
| JPH02116843A (ja) * | 1988-10-27 | 1990-05-01 | Konica Corp | 帯電防止されたハロゲン化銀写真感光材料 |
| JP2847164B2 (ja) * | 1989-05-19 | 1999-01-13 | ダウコーニングアジア株式会社 | 繊維体用抗菌剤 |
| DE10065710A1 (de) * | 2000-12-29 | 2002-07-04 | Bayer Ag | Arzneimittel enthaltend ein Polyamin als Wirksubstanz |
| US6955806B2 (en) * | 2001-01-18 | 2005-10-18 | Genzyme Corporation | Ionene polymers and their use as antimicrobial agents |
| WO2004046223A2 (en) * | 2002-11-19 | 2004-06-03 | Genzyme Corporation | Polyionene polymers with hydrolyzable linkages |
| WO2004046109A2 (en) * | 2002-11-19 | 2004-06-03 | Genzyme Corporation | Ionene oligomers and polymers |
| WO2004045629A1 (en) * | 2002-11-19 | 2004-06-03 | Genzyme Corporation | Polyionenes for treating infections associated with cystic fibrosis |
| US20100197888A1 (en) * | 2007-07-31 | 2010-08-05 | Polyplus Transfection | Method for Manufacturing Linear Polyethylenimine (PEI) for Transfection Purpose and Linear PEI Obtained with Such Method |
| WO2010044390A1 (ja) * | 2008-10-14 | 2010-04-22 | 株式会社日本触媒 | ポリアルキレンイミンを含むウイルス感染症治療薬 |
| US8853457B2 (en) * | 2010-01-04 | 2014-10-07 | Rhodia Operations | Polyamine and method for producing thereof |
| KR101291642B1 (ko) * | 2010-03-03 | 2013-08-01 | 성균관대학교산학협력단 | 폴리(아미도 아민) 올리고머 하이드로젤 조성물 및 이를 이용한 약물전달체 |
| NZ607000A (en) * | 2010-08-24 | 2015-02-27 | Imp Innovations Ltd | Glycodendrimers of polypropyletherimine |
| MX373164B (es) * | 2013-03-15 | 2020-05-07 | Genzyme Corp | Composiciones antimicrobianas de poliamida y tratamiento de mastitis. |
-
2015
- 2015-07-10 CN CN201580048444.5A patent/CN106687504A/zh active Pending
- 2015-07-10 AR ARP150102211A patent/AR101184A1/es unknown
- 2015-07-10 US US15/325,290 patent/US20170182087A1/en not_active Abandoned
- 2015-07-10 JP JP2017501288A patent/JP6765363B2/ja not_active Expired - Fee Related
- 2015-07-10 KR KR1020177003470A patent/KR20170028979A/ko not_active Withdrawn
- 2015-07-10 SG SG11201610886VA patent/SG11201610886VA/en unknown
- 2015-07-10 AU AU2015287661A patent/AU2015287661B2/en not_active Ceased
- 2015-07-10 WO PCT/US2015/039881 patent/WO2016007821A2/en not_active Ceased
- 2015-07-10 EP EP15739481.8A patent/EP3189091A2/en not_active Withdrawn
- 2015-07-10 MX MX2017000447A patent/MX2017000447A/es unknown
- 2015-07-10 BR BR112017000258A patent/BR112017000258A2/pt not_active Application Discontinuation
- 2015-07-10 RU RU2017104223A patent/RU2017104223A/ru not_active Application Discontinuation
- 2015-07-10 CA CA2954768A patent/CA2954768A1/en not_active Abandoned
- 2015-07-13 TW TW104122474A patent/TW201615694A/zh unknown
-
2017
- 2017-01-08 IL IL249963A patent/IL249963A0/en unknown
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