JP2017526728A - 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト - Google Patents
炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト Download PDFInfo
- Publication number
- JP2017526728A JP2017526728A JP2017514446A JP2017514446A JP2017526728A JP 2017526728 A JP2017526728 A JP 2017526728A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017526728 A JP2017526728 A JP 2017526728A
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- Prior art keywords
- montelukast
- levocetirizine
- virus
- combination
- disease
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050668P | 2014-09-15 | 2014-09-15 | |
| US62/050,668 | 2014-09-15 | ||
| PCT/US2015/049767 WO2016044095A1 (en) | 2014-09-15 | 2015-09-11 | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Division JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017526728A true JP2017526728A (ja) | 2017-09-14 |
| JP2017526728A5 JP2017526728A5 (cg-RX-API-DMAC7.html) | 2018-10-11 |
Family
ID=55533713
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514446A Pending JP2017526728A (ja) | 2014-09-15 | 2015-09-11 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US9925183B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3193875B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2017526728A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016044095A1 (cg-RX-API-DMAC7.html) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20190125943A (ko) * | 2018-04-27 | 2019-11-07 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| JP2022500437A (ja) * | 2018-09-14 | 2022-01-04 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| JP2023517536A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 炎症状態に使用するための化合物 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011159821A1 (en) | 2010-06-16 | 2011-12-22 | Bruce Chandler May | Use of levocetirizine and montelukast in the treatment of influenza, common cold and inflammation |
| CN105228700A (zh) | 2013-03-13 | 2016-01-06 | 炎症反应研究公司 | 左西替利嗪和孟鲁司特在治疗自身免疫病中的用途 |
| EP2968309A4 (en) | 2013-03-13 | 2016-08-31 | Inflammatory Response Res Inc | USE OF LEVOCETRIXIN AND MONTELUKAST IN THE TREATMENT OF VASCULARITY |
| CN105517631A (zh) | 2013-03-13 | 2016-04-20 | 炎症反应研究公司 | 左西替利嗪和孟鲁司特在治疗创伤性损伤中的用途 |
| EP3193875B1 (en) | 2014-09-15 | 2022-02-16 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| JP2021536467A (ja) * | 2018-09-06 | 2021-12-27 | インノファーマスクリーン インコーポレイテッド | 喘息またはパーキンソン病の処置のための方法および組成物 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| US20240000773A1 (en) * | 2020-05-19 | 2024-01-04 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040180868A1 (en) * | 2003-03-12 | 2004-09-16 | Mullally John P. | Composition and method for treating inflammations by reducing C-reactive protein |
| US20050256131A1 (en) * | 2002-05-24 | 2005-11-17 | Carl-Fr Coester | Pharmaceutical active substance combination and the use thereof |
| JP2013528654A (ja) * | 2010-06-16 | 2013-07-11 | ブルース・チャンドラー・メイ | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| WO2013148366A1 (en) * | 2012-03-27 | 2013-10-03 | Duke Unversity | Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage |
| CN103505731A (zh) * | 2012-06-15 | 2014-01-15 | 中国药科大学 | 1型半胱氨酰白三烯受体拮抗剂在制备用于治疗阿尔茨海默病的药物中的用途 |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801612A (en) | 1986-07-03 | 1989-01-31 | Regents Of The University Of California | Method of inhibiting inflammatory response |
| US5211958A (en) | 1987-11-30 | 1993-05-18 | Gist-Brocades, N.V. | Pharmaceutical composition and process for its preparation |
| US5147637A (en) | 1988-06-07 | 1992-09-15 | The Rockefeller University | Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma |
| EP0612256B1 (en) | 1991-11-14 | 1998-07-22 | Alliance Pharmaceutical Corporation | Apparatus for partial liquid ventilation using fluorocarbons |
| WO1995009652A1 (en) | 1993-10-06 | 1995-04-13 | The Kennedy Institute For Rheumatology | Treatment of autoimmune and inflammatory disorders |
| EP0994717A4 (en) | 1997-01-24 | 2000-07-26 | Autoimmune Inc | TREATING AUTOIMMUNE DISEASES BY TOLERANCE INCREASED BY COMBINING WITH METHOTREXATE |
| PL193131B1 (pl) | 1997-12-23 | 2007-01-31 | Schering Corp | Kompozycja farmaceutyczna zawierająca kombinację składników aktywnych i jej zastosowanie |
| AU2470299A (en) | 1998-01-27 | 1999-08-09 | Nutramax Laboratories, Inc. | Combinations of tyrosine, methylating agents, phospholipids, fatty acids, and st. john's wort for the treatment of mental disturbances |
| US6384038B1 (en) | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| US7186555B1 (en) | 1999-04-13 | 2007-03-06 | The Feinstein Institute For Medical Research | Prevention of brain damage in stroke |
| US20020006961A1 (en) | 1999-05-14 | 2002-01-17 | Katz Stanley E. | Method and composition for treating mammalian nasal and sinus diseases caused by inflammatory response |
| DE10007203A1 (de) | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| US20010051624A1 (en) | 2000-04-12 | 2001-12-13 | Jones Thomas R. | Method and compositions for the treatment of allergic conditions using PGD2 receptor antagonists |
| US20020052312A1 (en) | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
| JP2004505046A (ja) | 2000-07-28 | 2004-02-19 | イムファルム・アンパルトセルスカブ | 感冒、アレルギー性鼻炎および気道に関連した感染症の症状の処置方法 |
| US7718198B2 (en) | 2001-06-20 | 2010-05-18 | Metaproteomics, Llc | Treatment modalities for autoimmune diseases |
| ATE432068T1 (de) | 2001-06-28 | 2009-06-15 | Ucb Farchim Sa | Cetirizin und pseudoephedrin enthaltende tablette |
| US20050176687A1 (en) | 2001-06-29 | 2005-08-11 | Alain Moussy | Use of tyrosine kinase inhibitors for treating autoimmune diseases |
| HU224941B1 (en) | 2001-08-10 | 2006-04-28 | Bgi Innovacios Kft | Phototerapy apparatus |
| AU2003264859A1 (en) | 2001-12-21 | 2003-12-19 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
| US7291331B1 (en) | 2002-09-11 | 2007-11-06 | La Jolla Institute For Allergy And Immunology | Methods of treating OX40 medicated recall immune responses |
| US7666417B2 (en) | 2003-04-22 | 2010-02-23 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating autoimmune diseases or conditions |
| US20060263350A1 (en) | 2003-09-26 | 2006-11-23 | Fairfield Clinical Trials Llc | Combination antihistamine medication |
| WO2006010283A1 (en) | 2004-07-28 | 2006-02-02 | Universität Zürich | Prevention and treatment of thrombus formation |
| AU2005294666A1 (en) | 2004-10-05 | 2006-04-20 | Genentech, Inc. | Method for treating vasculitis |
| US20070244128A1 (en) | 2005-11-04 | 2007-10-18 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
| US20070225285A1 (en) * | 2005-11-04 | 2007-09-27 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
| WO2007056510A2 (en) | 2005-11-09 | 2007-05-18 | The Children's Hospital Of Philadelphia | Chloride transport upregulation for the treatment of traumatic brain injury |
| ES2389231T3 (es) | 2005-12-21 | 2012-10-24 | Meda Pharma Gmbh & Co. Kg | Combinación de anticolinérgicos, glucocorticoides y agonistas de beta2 para el tratamiento de enfermedades inflamatorias |
| US8207292B2 (en) | 2007-02-12 | 2012-06-26 | Michalis Nicolaou | Treatment of COPD, gastro-esophageal reflux disease (GERD), food allergies and other gastrointestinal conditions and disorders ameliorated by proper histamine management using a combination of histidine decarboxylase inhibitors, LRA drugs, anti-H1 and/or anti-H2 drugs |
| US7589076B2 (en) | 2006-05-18 | 2009-09-15 | Pgx Health, Llc | Substituted aryl piperidinylalkynyladenosines as A2AR agonists |
| EP2129683A4 (en) | 2007-02-26 | 2011-01-05 | Ironwood Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATMENT OF HEART FAILURE AND OTHER DISORDERS |
| KR20100059836A (ko) | 2007-08-15 | 2010-06-04 | 케마지스 리미티드 | 고순도 레보세티리진 및 이의 염을 제조하기 위한 신규한 방법 |
| CA2701723A1 (en) | 2007-10-25 | 2009-04-30 | Merck Frosst Canada Ltd. | Novel crystalline salts of montelukast |
| US20090227018A1 (en) | 2007-10-25 | 2009-09-10 | Revalesio Corporation | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
| WO2009055614A1 (en) | 2007-10-25 | 2009-04-30 | Revalesio Corporation | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
| HRP20140686T1 (hr) | 2009-03-02 | 2014-09-26 | Generics | Poboljšani postupak |
| WO2010107404A1 (en) | 2009-03-16 | 2010-09-23 | Mahmut Bilgic | Stable pharmaceutical combinations |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| GB2474748B (en) | 2009-10-01 | 2011-10-12 | Amira Pharmaceuticals Inc | Polycyclic compounds as lysophosphatidic acid receptor antagonists |
| RU2012136624A (ru) | 2010-01-28 | 2014-03-10 | Мерк Шарп Энд Домэ Корп. | Фармацевтические композиции для лечения боли и других показаний |
| US20120002637A1 (en) | 2010-06-18 | 2012-01-05 | Interdigital Patent Holdings, Inc. | Method and apparatus for supporting home node-b mobility |
| EP2598143A1 (en) | 2010-07-28 | 2013-06-05 | Boehringer Ingelheim International GmbH | Pharmaceutical compositions for treatment of respiratory and inflammatory diseases |
| TR201009398A2 (tr) | 2010-11-11 | 2012-05-21 | Bi̇lgi̇ç Mahmut | Fiziksel özellikleri geliştirilmiş tablet formülasyonları |
| US20130030009A1 (en) | 2010-12-30 | 2013-01-31 | Ziv Harish | Method for the treatment and/or prevention of oral allergic symptions of the lips due to oral contact with a food allergen |
| EP2658538A2 (en) | 2010-12-30 | 2013-11-06 | M.D. Ziv Harish | Preparations for topical prevention and/or treatment of oral allergic symptoms due to oral contact with fruits and/or vegetables |
| CN103561722A (zh) | 2011-04-13 | 2014-02-05 | 利发利希奥公司 | 用于抑制和/或调整炎性神经变性疾病中涉及到的效应t细胞的组合物和方法 |
| EP2520292A1 (en) | 2011-05-06 | 2012-11-07 | Helmholtz-Zentrum für Infektionsforschung GmbH | Use of spirangiens for the treatment or prevention of IL-8 or IL-6 mediated disorders |
| KR20130009553A (ko) | 2011-07-15 | 2013-01-23 | 한미약품 주식회사 | 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제 |
| JP5860960B2 (ja) | 2011-07-26 | 2016-02-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換キノリン類及び医薬としてのそれらの使用 |
| CN102895661A (zh) | 2011-07-28 | 2013-01-30 | 中国科学院上海药物研究所 | 靶向CysLT1的药物在制备用于预防或治疗自身免疫性疾病的药物中的用途 |
| RU2705097C2 (ru) | 2013-03-13 | 2019-11-05 | Ирр, Инк. | Применение левоцетиризина и монтелукаста при лечении анафилаксии |
| EP2968309A4 (en) | 2013-03-13 | 2016-08-31 | Inflammatory Response Res Inc | USE OF LEVOCETRIXIN AND MONTELUKAST IN THE TREATMENT OF VASCULARITY |
| CN105228700A (zh) | 2013-03-13 | 2016-01-06 | 炎症反应研究公司 | 左西替利嗪和孟鲁司特在治疗自身免疫病中的用途 |
| CN105517631A (zh) | 2013-03-13 | 2016-04-20 | 炎症反应研究公司 | 左西替利嗪和孟鲁司特在治疗创伤性损伤中的用途 |
| US9371282B2 (en) | 2013-05-17 | 2016-06-21 | Centrexion Therapeutics Corporation | Somatostatin receptor subtype 4 (SSTR4) agonists |
| EP3193875B1 (en) | 2014-09-15 | 2022-02-16 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| JP2019517581A (ja) | 2016-06-03 | 2019-06-24 | アイ・アール・アール・インコーポレイテッド | 放射線媒介性状態の処置におけるレボセチリジン及びモンテルカスト |
| US20240000773A1 (en) | 2020-05-19 | 2024-01-04 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
-
2015
- 2015-09-11 EP EP15841696.6A patent/EP3193875B1/en active Active
- 2015-09-11 JP JP2017514446A patent/JP2017526728A/ja active Pending
- 2015-09-11 WO PCT/US2015/049767 patent/WO2016044095A1/en not_active Ceased
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2017
- 2017-03-06 US US15/450,840 patent/US9925183B2/en active Active
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2018
- 2018-02-13 US US15/895,918 patent/US10195193B2/en active Active
- 2018-12-18 US US16/224,573 patent/US10792281B2/en active Active
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2020
- 2020-04-09 JP JP2020070422A patent/JP2020109128A/ja active Pending
- 2020-08-31 US US17/007,902 patent/US11590125B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050256131A1 (en) * | 2002-05-24 | 2005-11-17 | Carl-Fr Coester | Pharmaceutical active substance combination and the use thereof |
| US20040180868A1 (en) * | 2003-03-12 | 2004-09-16 | Mullally John P. | Composition and method for treating inflammations by reducing C-reactive protein |
| JP2013528654A (ja) * | 2010-06-16 | 2013-07-11 | ブルース・チャンドラー・メイ | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| WO2013148366A1 (en) * | 2012-03-27 | 2013-10-03 | Duke Unversity | Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage |
| CN103505731A (zh) * | 2012-06-15 | 2014-01-15 | 中国药科大学 | 1型半胱氨酰白三烯受体拮抗剂在制备用于治疗阿尔茨海默病的药物中的用途 |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
Non-Patent Citations (1)
| Title |
|---|
| NEUROPHARMCOLOGY, vol. 79, JPN6019019029, April 2014 (2014-04-01), pages 707 - 714, ISSN: 0004041719 * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20190125943A (ko) * | 2018-04-27 | 2019-11-07 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20200116068A (ko) * | 2018-04-27 | 2020-10-08 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20200116069A (ko) * | 2018-04-27 | 2020-10-08 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269664B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269663B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269665B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| JP2022500437A (ja) * | 2018-09-14 | 2022-01-04 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| JP7759693B2 (ja) | 2018-09-14 | 2025-10-24 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| JP2023517536A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 炎症状態に使用するための化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US11590125B2 (en) | 2023-02-28 |
| US20180169091A1 (en) | 2018-06-21 |
| US20190201393A1 (en) | 2019-07-04 |
| JP2020109128A (ja) | 2020-07-16 |
| US20170173001A1 (en) | 2017-06-22 |
| WO2016044095A1 (en) | 2016-03-24 |
| EP3193875B1 (en) | 2022-02-16 |
| US9925183B2 (en) | 2018-03-27 |
| US20210177835A1 (en) | 2021-06-17 |
| EP3193875A1 (en) | 2017-07-26 |
| US10792281B2 (en) | 2020-10-06 |
| US10195193B2 (en) | 2019-02-05 |
| EP3193875A4 (en) | 2018-05-23 |
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