JP2017526627A5 - - Google Patents

Download PDF

Info

Publication number
JP2017526627A5
JP2017526627A5 JP2016574989A JP2016574989A JP2017526627A5 JP 2017526627 A5 JP2017526627 A5 JP 2017526627A5 JP 2016574989 A JP2016574989 A JP 2016574989A JP 2016574989 A JP2016574989 A JP 2016574989A JP 2017526627 A5 JP2017526627 A5 JP 2017526627A5
Authority
JP
Japan
Prior art keywords
sequence number
polypeptide
seq
fragment
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016574989A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017526627A (ja
JP6818349B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/037962 external-priority patent/WO2015200783A2/en
Publication of JP2017526627A publication Critical patent/JP2017526627A/ja
Publication of JP2017526627A5 publication Critical patent/JP2017526627A5/ja
Application granted granted Critical
Publication of JP6818349B2 publication Critical patent/JP6818349B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016574989A 2014-06-26 2015-06-26 アシネトバクター溶解素 Expired - Fee Related JP6818349B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462017618P 2014-06-26 2014-06-26
US62/017,618 2014-06-26
PCT/US2015/037962 WO2015200783A2 (en) 2014-06-26 2015-06-26 Acinetobacter lysins

Publications (3)

Publication Number Publication Date
JP2017526627A JP2017526627A (ja) 2017-09-14
JP2017526627A5 true JP2017526627A5 (enExample) 2018-08-09
JP6818349B2 JP6818349B2 (ja) 2021-01-20

Family

ID=54938953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016574989A Expired - Fee Related JP6818349B2 (ja) 2014-06-26 2015-06-26 アシネトバクター溶解素

Country Status (14)

Country Link
US (2) US10590403B2 (enExample)
EP (1) EP3164146B1 (enExample)
JP (1) JP6818349B2 (enExample)
KR (1) KR102441211B1 (enExample)
CN (1) CN106659748B (enExample)
AU (1) AU2015279705B2 (enExample)
BR (1) BR112016030580B1 (enExample)
CA (1) CA2953446A1 (enExample)
ES (1) ES2767294T3 (enExample)
GB (1) GB2543453A (enExample)
IL (1) IL249636A0 (enExample)
NZ (1) NZ728429A (enExample)
RU (1) RU2725809C2 (enExample)
WO (1) WO2015200783A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106659748B (zh) * 2014-06-26 2021-08-31 洛克菲勒大学 不动杆菌属溶素
MX2020006098A (es) 2017-12-12 2020-08-24 Contrafect Corp Lisinas y sus derivados con actividad bactericida contra pseudomona aeruginosa, en la presencia de suero humano.
JP2021519083A (ja) 2018-03-29 2021-08-10 コントラフェクト コーポレイション 溶解素−抗微生物ペプチド(amp)ポリペプチドコンストラクト、溶解素、それをコードする単離ポリヌクレオチド及びその使用
US10988520B2 (en) 2018-03-29 2021-04-27 Contrafect Corporation Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
JP2021533728A (ja) * 2018-08-23 2021-12-09 コントラフェクト コーポレイション 溶解素−抗微生物ペプチド(amp)ポリペプチドコンストラクト、溶解素、それをコードする単離ポリヌクレオチド及びその使用
CN114040773A (zh) * 2019-04-05 2022-02-11 康特拉费克特公司 在存在人血清的情况下对铜绿假单胞菌具有杀菌活性的溶素及其衍生物
CN111909917B (zh) * 2019-05-10 2022-10-14 中国科学院微生物研究所 一种内溶素Lysmeta1及其编码基因与应用
CA3175024A1 (en) 2020-03-11 2021-09-16 Telum Therapeutics S.L. New recombinant lysin and its use in the treatment of gram-negative bacterial infections
KR102604590B1 (ko) * 2020-09-28 2023-11-23 경북대학교 산학협력단 아시네토박터 바우마니에 대한 사멸능을 가지는 박테리오파지 및 이를 포함하는 조성물
KR102419028B1 (ko) * 2021-01-06 2022-07-08 주식회사 리신바이오 박테리오파지 유래 신규 재조합 엔도라이신 및 이의 용도
WO2022236088A1 (en) * 2021-05-06 2022-11-10 Bioharmony Therapeutics Inc. Lysin polypeptide compositions and methods of use
KR102776341B1 (ko) * 2023-11-24 2025-03-10 경북대학교 산학협력단 아시네토박터 바우마니에 대한 특이적 결합능을 갖는 재조합 단백질 및 이의 용도

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030113298A1 (en) * 1997-10-31 2003-06-19 Vincent Fischetti Use of bacterial phage associated lysing proteins for the prophylactic and therapeutic treatment of various illnesses
US20060292135A1 (en) * 1997-10-31 2006-12-28 Lawrence Loomis Use of bacterial phage-associated lysing proteins for preventing and treating bacterial infections in humans, animals and fowl
US6056954A (en) * 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US5997862A (en) * 1997-10-31 1999-12-07 New Horizons Diagnostics Corporation Therapeutic treatment of group A streptococcal infections
US6562958B1 (en) * 1998-06-09 2003-05-13 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Acinetobacter baumannii for diagnostics and therapeutics
US6133010A (en) 1999-07-08 2000-10-17 Biotec Asa Chlamysin B antibacterial protein, a protein gene for and an expression system for same
US20100233146A1 (en) * 2002-09-09 2010-09-16 Reactive Surfaces, Ltd. Coatings and Surface Treatments Having Active Enzymes and Peptides
US7604975B2 (en) * 2002-10-01 2009-10-20 The Rockefeller University Glycosylated LPXTGases and uses thereof
US7320795B2 (en) * 2003-07-30 2008-01-22 Vaccine Research Institute Of San Diego Rodent hepatitis B virus core proteins as vaccine platforms and methods of use thereof
US7144712B2 (en) * 2003-07-30 2006-12-05 Vaccine Research Institute Of San Diego Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof
WO2005011571A2 (en) * 2003-07-30 2005-02-10 Vaccine Research Institute Of San Diego Hepatitis virus core proteins as vaccine platforms and methods of use thereof
US20070077235A1 (en) * 2004-01-16 2007-04-05 Lawrence Loomis Composition and method of treating mastitis
EP2046363A1 (en) 2006-07-10 2009-04-15 Österreichische Akademie der Wissenschaften Antimicrobial peptides
US9999635B2 (en) * 2007-01-16 2018-06-19 Realm Therapeutics, Inc. Methods and compositions for treating inflammatory disorders
EP2217614A4 (en) * 2007-11-07 2011-12-07 Dynamic Microbials Ltd ANTIMICROBIAL COMPOSITIONS, FORMULATIONS AND APPLICATIONS THEREOF
EP2157100A1 (en) * 2008-08-19 2010-02-24 Profos AG Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins
GB0815484D0 (en) * 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
AU2009296458A1 (en) * 2008-09-26 2010-04-01 Nanobio Corporation Nanoemulsion therapeutic compositions and methods of using the same
ES2467691T3 (es) * 2008-11-28 2014-06-12 Anges Mg, Inc. Polipéptido novedoso que tiene actividad de inducción de la angiogénesis y una actividad antibacteriana y uso del mismo para propósitos médicos
KR101016918B1 (ko) 2009-01-08 2011-02-25 주식회사 인트론바이오테크놀로지 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질
SI2445515T1 (sl) * 2009-06-26 2016-08-31 Lysando Ag Antimikrobna sredstva
EP2470648B1 (en) 2009-08-24 2019-04-10 Katholieke Universiteit Leuven K.U. Leuven R&D New endolysin obpgplys
WO2011084882A2 (en) * 2010-01-05 2011-07-14 Contrafect Corporation Methods and compositions for enhanced immunological therapy and targeting of gram-positive bacteria
WO2011134998A1 (en) * 2010-04-27 2011-11-03 Lysando Holding Ag Method of reducing biofilms
PT3443970T (pt) * 2010-09-17 2020-10-09 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fagos antibacterianos, péptidos fágicos e métodos de utilização dos mesmos
EP2468856A1 (en) 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimicrobial Agents
GB201103780D0 (en) * 2011-03-04 2011-04-20 Hansa Medical Ab Treatment for ige-mediated disease
US9034322B2 (en) * 2011-04-21 2015-05-19 The Rockefeller University Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria
HUE047099T2 (hu) * 2011-10-08 2020-04-28 Next Science IP Holdings Pty Ltd Antimikrobiális kompozíciók és eljárások alkalmazásukra
KR20230135161A (ko) * 2012-05-09 2023-09-22 콘트라펙트 코포레이션 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료
US10813983B2 (en) * 2012-05-09 2020-10-27 Contrafect Corporation Bacteriophage lysin and antibiotic combinations against gram positive bacteria
KR101391332B1 (ko) * 2012-05-18 2014-05-07 연세대학교 산학협력단 카바페넴 제제에 내성을 보이는 아시네토박터 속의 균을 용균하는 박테리오파아지
CA2907988A1 (en) * 2012-08-08 2014-02-13 Avacyn Pharmaceuticals, Inc. Inhibition of antimicrobial targets with reduced potential for resistance
CN102940874B (zh) * 2012-12-12 2013-12-18 中国科学院昆明动物研究所 小分子多肽cw14在制备山羊抗菌药物中的应用
CN105101796B (zh) * 2013-02-06 2017-06-06 中央研究院 衍生自b型肝炎病毒核蛋白精氨酸密集区的抗菌胜肽
CN106659748B (zh) * 2014-06-26 2021-08-31 洛克菲勒大学 不动杆菌属溶素
JP6863966B2 (ja) * 2015-08-25 2021-04-21 シャアメン ユニバーシティ 標的ポリペプチドを提示するためのポリペプチド担体及びその使用
CA2998484A1 (en) * 2015-09-17 2017-03-23 Contrafect Corporation Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby
US10851401B2 (en) * 2016-05-12 2020-12-01 Contrafect Corporation Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides
MY201964A (en) * 2016-06-20 2024-03-27 Isa Pharmaceuticals B V Formulation of a peptide vaccine
US10988520B2 (en) * 2018-03-29 2021-04-27 Contrafect Corporation Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
JP2021519083A (ja) * 2018-03-29 2021-08-10 コントラフェクト コーポレイション 溶解素−抗微生物ペプチド(amp)ポリペプチドコンストラクト、溶解素、それをコードする単離ポリヌクレオチド及びその使用
EP3813796A4 (en) * 2018-05-23 2022-06-22 The Rockefeller University RECOMBINED LYSINES
JP2021533728A (ja) * 2018-08-23 2021-12-09 コントラフェクト コーポレイション 溶解素−抗微生物ペプチド(amp)ポリペプチドコンストラクト、溶解素、それをコードする単離ポリヌクレオチド及びその使用

Similar Documents

Publication Publication Date Title
JP2017526627A5 (enExample)
Batoni et al. Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections
JP7267251B2 (ja) 抗菌組成物及び医薬組成物
Kosikowska et al. Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)
Weber-Dąbrowska et al. Phage therapy of staphylococcal infections (including MRSA) may be less expensive than antibiotic treatment
CN102906105B (zh) 肽及其用途
Blanchette et al. Current therapies in treatment and prevention of fracture wound biofilms: why a multifaceted approach is essential for resolving persistent infections
JP2013541333A5 (enExample)
RU2017102306A (ru) Лизины ацинетобактеров
RU2018107249A (ru) Применение лизина для восстановления/увеличения антибактериальной активности антибиотиков в присутствии легочного сурфактанта, который ингибирует указанные антибиотики
RU2018146644A (ru) Композиции на основе каннабидиола и пути их применения
JP2014500714A5 (enExample)
JP2018512454A5 (enExample)
WO2020060401A2 (en) Bioactive peptides derived from snakes
US20220048959A1 (en) Antimicrobial protein
JP2020040950A (ja) 広域スペクトル抗感染ペプチド
JP2013539776A5 (enExample)
JP2018531880A5 (enExample)
JP2014503469A5 (enExample)
HUE029860T2 (en) Antimicrobial peptides against infectious diseases
JP2019523220A5 (enExample)
JP2020117504A5 (enExample)
US20220071902A1 (en) Solution and method for reducing the virulence of viruses, bacteria, yeasts, or fungus
JP6506317B2 (ja) ペプチドおよびその使用
US8937038B2 (en) Composition containing peptide ligand that bonds with CXCR2 for treating infective and inflammatory diseases