JP2017525668A5 - - Google Patents

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Publication number
JP2017525668A5
JP2017525668A5 JP2016575768A JP2016575768A JP2017525668A5 JP 2017525668 A5 JP2017525668 A5 JP 2017525668A5 JP 2016575768 A JP2016575768 A JP 2016575768A JP 2016575768 A JP2016575768 A JP 2016575768A JP 2017525668 A5 JP2017525668 A5 JP 2017525668A5
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JP
Japan
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optionally substituted
pharmaceutically acceptable
acceptable salt
compound
heterocyclyl
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JP2016575768A
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English (en)
Japanese (ja)
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JP6663866B2 (ja
JP2017525668A (ja
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Priority claimed from PCT/US2015/038345 external-priority patent/WO2016003917A1/en
Publication of JP2017525668A publication Critical patent/JP2017525668A/ja
Publication of JP2017525668A5 publication Critical patent/JP2017525668A5/ja
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Publication of JP6663866B2 publication Critical patent/JP6663866B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016575768A 2014-07-03 2015-06-29 リジン特異的なデメチラーゼ−１の阻害剤 Expired - Fee Related JP6663866B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462020886P 2014-07-03 2014-07-03
US62/020,886 2014-07-03
PCT/US2015/038345 WO2016003917A1 (en) 2014-07-03 2015-06-29 Inhibitors of lysine specific demethylase-1

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019029856A Division JP6768857B2 (ja) 2014-07-03 2019-02-21 リジン特異的なデメチラーゼ−１の阻害剤

Publications (3)

Publication Number Publication Date
JP2017525668A JP2017525668A (ja) 2017-09-07
JP2017525668A5 true JP2017525668A5 (esLanguage) 2018-05-31
JP6663866B2 JP6663866B2 (ja) 2020-03-13

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JP2016575768A Expired - Fee Related JP6663866B2 (ja) 2014-07-03 2015-06-29 リジン特異的なデメチラーゼ−１の阻害剤
JP2019029856A Expired - Fee Related JP6768857B2 (ja) 2014-07-03 2019-02-21 リジン特異的なデメチラーゼ−１の阻害剤

Family Applications After (1)

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JP2019029856A Expired - Fee Related JP6768857B2 (ja) 2014-07-03 2019-02-21 リジン特異的なデメチラーゼ−１の阻害剤

Country Status (29)

Country Link
US (3) US9902719B2 (esLanguage)
EP (2) EP3511319B1 (esLanguage)
JP (2) JP6663866B2 (esLanguage)
KR (1) KR102475498B1 (esLanguage)
CN (2) CN108530424B (esLanguage)
AU (1) AU2015284383B2 (esLanguage)
BR (1) BR112017000043A2 (esLanguage)
CA (1) CA2954049A1 (esLanguage)
CL (1) CL2016003422A1 (esLanguage)
CO (1) CO2017000549A2 (esLanguage)
CY (1) CY1125127T1 (esLanguage)
DK (2) DK3511319T3 (esLanguage)
EA (2) EA033698B1 (esLanguage)
EC (1) ECSP17006821A (esLanguage)
ES (2) ES2948782T3 (esLanguage)
FI (1) FI3511319T3 (esLanguage)
HR (2) HRP20220414T1 (esLanguage)
HU (2) HUE058852T2 (esLanguage)
IL (2) IL249881B (esLanguage)
LT (2) LT3164380T (esLanguage)
MX (2) MX395534B (esLanguage)
PL (2) PL3164380T3 (esLanguage)
PT (2) PT3511319T (esLanguage)
RS (2) RS63074B1 (esLanguage)
SA (1) SA517380651B1 (esLanguage)
SG (2) SG11201610975RA (esLanguage)
SI (2) SI3164380T1 (esLanguage)
SM (2) SMT202200136T1 (esLanguage)
WO (1) WO2016003917A1 (esLanguage)

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WO2017013061A1 (en) 2015-07-17 2017-01-26 Oryzon Genomics, S.A. Biomarkers associated with lsd1 inhibitors and uses thereof
CN109195593A (zh) 2016-03-15 2019-01-11 奥莱松基因组股份有限公司 用于治疗实体瘤的lsd1抑制剂的组合
US11034991B2 (en) 2016-03-16 2021-06-15 Oryzon Genomics S.A. Methods to determine KDM1A target engagement and chemoprobes useful therefor
US10150754B2 (en) 2016-04-19 2018-12-11 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
EP3535420A1 (en) 2016-11-03 2019-09-11 Oryzon Genomics, S.A. Biomarkers for determining responsiveness to lsd1 inhibitors
BR112020000827A2 (pt) 2017-08-03 2020-07-21 Oryzon Genomics, S.A. métodos de tratamento de alterações de comportamento
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US12479845B2 (en) 2019-02-01 2025-11-25 Hanmi Pharm. Co., Ltd. Imidazopyridine derivative compounds and use of same
AU2020216034B2 (en) * 2019-02-01 2024-12-19 Hanmi Pharm. Co., Ltd. Imidazopyridine derivative compounds and use of same
SG11202109159VA (en) 2019-03-20 2021-10-28 Oryzon Genomics Sa Methods of treating borderline personality disorder
ES3053813T3 (en) 2019-03-20 2026-01-26 Oryzon Genomics Sa Methods of treating attention deficit hyperactivity disorder using kdm1a inhibitors such as the compound vafidemstat
EP3994280A1 (en) 2019-07-05 2022-05-11 Oryzon Genomics, S.A. Biomarkers and methods for personalized treatment of small cell lung cancer using kdm1a inhibitors
US11360505B2 (en) 2020-02-11 2022-06-14 Simmonds Precision Products, Inc. Distributed network time synchronization
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WO2022199662A1 (zh) * 2021-03-24 2022-09-29 四川汇宇制药股份有限公司 一种多环化合物及其应用
EP4319732A1 (en) 2021-04-08 2024-02-14 Oryzon Genomics, S.A. Combinations of lsd1 inhibitors for treating myeloid cancers
CN116102533A (zh) * 2021-11-11 2023-05-12 中国科学院上海药物研究所 一种芳杂环类化合物及其应用
CN119546292A (zh) 2022-05-09 2025-02-28 奥莱松基因组股份有限公司 使用lsd1抑制剂治疗恶性周围神经鞘瘤(mpnst)的方法
JP2025516648A (ja) 2022-05-09 2025-05-30 オリゾン・ゲノミクス・ソシエダッド・アノニマ Ｌｓｄ１阻害薬を用いるｎｆ１変異腫瘍の治療法
EP4622635A1 (en) 2022-11-24 2025-10-01 Oryzon Genomics, S.A. Combinations of lsd1 inhibitors and menin inhibitors for treating cancer

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