|
NL154600B
(nl)
|
1971-02-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
|
|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
NL154599B
(nl)
|
1970-12-28 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
|
|
US3901654A
(en)
|
1971-06-21 |
1975-08-26 |
Biological Developments |
Receptor assays of biologically active compounds employing biologically specific receptors
|
|
US3853987A
(en)
|
1971-09-01 |
1974-12-10 |
W Dreyer |
Immunological reagent and radioimmuno assay
|
|
US3867517A
(en)
|
1971-12-21 |
1975-02-18 |
Abbott Lab |
Direct radioimmunoassay for antigens and their antibodies
|
|
NL171930C
(nl)
|
1972-05-11 |
1983-06-01 |
Akzo Nv |
Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
|
|
US3850578A
(en)
|
1973-03-12 |
1974-11-26 |
H Mcconnell |
Process for assaying for biologically active molecules
|
|
US3935074A
(en)
|
1973-12-17 |
1976-01-27 |
Syva Company |
Antibody steric hindrance immunoassay with two antibodies
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4034074A
(en)
|
1974-09-19 |
1977-07-05 |
The Board Of Trustees Of Leland Stanford Junior University |
Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
|
|
US3984533A
(en)
|
1975-11-13 |
1976-10-05 |
General Electric Company |
Electrophoretic method of detecting antigen-antibody reaction
|
|
US4036945A
(en)
|
1976-05-03 |
1977-07-19 |
The Massachusetts General Hospital |
Composition and method for determining the size and location of myocardial infarcts
|
|
US4098876A
(en)
|
1976-10-26 |
1978-07-04 |
Corning Glass Works |
Reverse sandwich immunoassay
|
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4348376A
(en)
|
1980-03-03 |
1982-09-07 |
Goldenberg Milton David |
Tumor localization and therapy with labeled anti-CEA antibody
|
|
US4879219A
(en)
|
1980-09-19 |
1989-11-07 |
General Hospital Corporation |
Immunoassay utilizing monoclonal high affinity IgM antibodies
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5011771A
(en)
|
1984-04-12 |
1991-04-30 |
The General Hospital Corporation |
Multiepitopic immunometric assay
|
|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6022958A
(en)
|
1986-08-13 |
2000-02-08 |
Bayer Corporation |
cDNAs coding for members of the carcinoembryonic antigen family
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5096815A
(en)
|
1989-01-06 |
1992-03-17 |
Protein Engineering Corporation |
Generation and selection of novel dna-binding proteins and polypeptides
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
ATE207080T1
(de)
|
1991-11-25 |
2001-11-15 |
Enzon Inc |
Multivalente antigen-bindende proteine
|
|
DE69309472T2
(de)
|
1992-01-23 |
1997-10-23 |
Merck Patent Gmbh, 64293 Darmstadt |
Fusionsproteine von monomeren und dimeren von antikörperfragmenten
|
|
US5281521A
(en)
|
1992-07-20 |
1994-01-25 |
The Trustees Of The University Of Pennsylvania |
Modified avidin-biotin technique
|
|
EP0787185A2
(en)
|
1994-10-20 |
1997-08-06 |
MorphoSys AG |
Targeted hetero-association of recombinant proteins to multi-functional complexes
|
|
GB9421405D0
(en)
|
1994-10-21 |
1994-12-07 |
Dow Chemical Co |
Low voc laminating formulations
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
CA2222055A1
(en)
|
1995-05-23 |
1996-11-28 |
Morphosys Gesellschaft Fur Proteinoptimierung Mbh |
Multimeric proteins
|
|
ES2246567T3
(es)
|
1998-04-15 |
2006-02-16 |
Brigham & Womens Hospital |
Composiciones para receptores inhibidores de celulas t y usos de las mismas.
|
|
DE19852804C1
(de)
|
1998-11-16 |
1999-12-23 |
Christoph Wagener |
Beeinflussung der Angiogenese durch CD66a
|
|
AU6940700A
(en)
|
1999-08-26 |
2001-03-19 |
Amy P. N Skubitz |
Peptides capable of modulating the function of cd66 (ceacam) family members
|
|
DE10016877A1
(de)
|
2000-04-05 |
2001-10-18 |
Scintec Diagnostics Gmbh Zug |
(Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung
|
|
SE0002835D0
(sv)
|
2000-08-07 |
2000-08-07 |
Karolinska Innovations Ab |
Method and kit for production of monoclonal antibodies
|
|
EP1472276A4
(en)
|
2001-02-28 |
2007-05-09 |
Keith M Skubitz |
PEPTIDES OF SMALL SIZE CAPACITY TO MODULATE THE FUNCTION OF THE MEMBERS OF THE FAMILY OF CD66 (CEACAM)
|
|
US20030022292A1
(en)
|
2001-06-07 |
2003-01-30 |
Gray-Owen Scott D. |
Ligation of CEACAM1
|
|
US20060058257A1
(en)
|
2001-08-03 |
2006-03-16 |
Christoph Wagener |
Influencing angiogenesis using CD66a
|
|
US20050107324A1
(en)
|
2003-07-12 |
2005-05-19 |
Bennett C. F. |
Modulation of CEACAM1 expression
|
|
US20030211477A1
(en)
|
2002-04-05 |
2003-11-13 |
Holmes Kathryn V. |
Carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) structure and uses thereof in drug identification and screening
|
|
US20030190600A1
(en)
|
2002-04-05 |
2003-10-09 |
Dana-Faber Cancer Institute |
Carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) structure and uses thereof in drug identification and screening
|
|
CU23228A1
(en)
|
2002-04-29 |
2007-09-26 |
Ct Ingenieria Genetica Biotech |
FRAGMENTS OF SPECIFIC ANTIBODIES FOR THE HUMAN CARCINOEMBRIONARY ANTIGEN (CEA) SEQUENCES OF ITS VARIABLE REGIONS AND VECTORS FOR THE MICROBIAL EXPRESSION OF THE SAME
|
|
US20040047858A1
(en)
|
2002-09-11 |
2004-03-11 |
Blumberg Richard S. |
Therapeutic anti-BGP(C-CAM1) antibodies and uses thereof
|
|
CN101972478B
(zh)
|
2002-10-08 |
2012-10-31 |
免疫医疗公司 |
抗体治疗
|
|
KR20050073488A
(ko)
|
2002-10-08 |
2005-07-13 |
이뮤노메딕스, 인코오포레이티드 |
Ⅲ종 항-ｃｅａ 단클론 항체들 및 치료제들을 이용한 조합치료법
|
|
WO2005050200A2
(en)
|
2003-11-13 |
2005-06-02 |
Genentech, Inc. |
Screening assays and methods of tumor treatment
|
|
CA2572289A1
(en)
|
2004-06-30 |
2006-08-17 |
Centocor, Inc. |
Anti-mcp-1 antibodies, compositions, methods and uses
|
|
WO2007063424A2
(en)
|
2005-06-09 |
2007-06-07 |
Gal Markel |
The modulation of immunity and ceacam1 activity
|
|
US20090226444A1
(en)
|
2005-12-21 |
2009-09-10 |
Micromet Ag |
Pharmaceutical antibody compositions with resistance to soluble cea
|
|
JP5399712B2
(ja)
|
2005-12-21 |
2014-01-29 |
アムゲン リサーチ （ミュンヘン） ゲーエムベーハー |
可溶性ｃｅａに対する抵抗性を有する医薬組成物
|
|
WO2008029271A2
(en)
|
2006-02-27 |
2008-03-13 |
Gal Markel |
Ceacam based antibacterial agents
|
|
CN103864893B
(zh)
|
2007-07-27 |
2017-01-04 |
伊玛提克斯生物技术有限公司 |
免疫疗法的免疫抗原表位
|
|
WO2009033095A2
(en)
*
|
2007-09-07 |
2009-03-12 |
Cisthera, Incorporated |
Humanized pai-1 antibodies
|
|
WO2009141679A2
(en)
|
2007-11-05 |
2009-11-26 |
Gal Markel |
Ceacam1 based point-of-care cancer diagnostic
|
|
WO2009129538A2
(en)
*
|
2008-04-18 |
2009-10-22 |
Xencor, Inc. |
Human equivalent monoclonal antibodies engineered from nonhuman variable regions
|
|
WO2010072691A1
(en)
*
|
2008-12-22 |
2010-07-01 |
Novo Nordisk A/S |
Antibodies against tissue factor pathway inhibitor
|
|
KR20180077322A
(ko)
|
2009-04-30 |
2018-07-06 |
텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． |
항-ｃｅａｃａｍ1 항체들과 이를 이용하는 방법들
|
|
ES2753986T3
(es)
|
2009-07-21 |
2020-04-15 |
Tel Hashomer Medical Res Infrastructure & Services Ltd |
Un método de diagnóstico de cáncer
|
|
KR101528013B1
(ko)
|
2009-08-31 |
2015-06-16 |
로슈 글리카트 아게 |
친화성-성숙된 인간화된 항-ｃｅａ 단일클론 항체
|
|
JP2013508287A
(ja)
|
2009-10-14 |
2013-03-07 |
ヤンセン バイオテツク，インコーポレーテツド |
抗体を親和性成熟する方法
|
|
WO2013054320A1
(en)
*
|
2011-10-11 |
2013-04-18 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
|
|
US9556271B2
(en)
|
2011-12-01 |
2017-01-31 |
The Brigham And Women's Hospital, Inc. |
Anti-CEACAM1 recombinant antibodies for cancer therapy
|
|
CN104011925A
(zh)
|
2011-12-27 |
2014-08-27 |
株式会社Lg化学 |
锂二次电池及其制备方法
|
|
US20150337037A1
(en)
*
|
2012-06-05 |
2015-11-26 |
Msm Protein Technologies |
Human monoclonal antibodies against human chemokine receptor ccr6
|
|
EP3539563A1
(en)
*
|
2012-07-19 |
2019-09-18 |
Redwood Bioscience, Inc. |
Antibody specific for cd22 and methods of use thereof
|
|
WO2014055967A2
(en)
*
|
2012-10-05 |
2014-04-10 |
Neotope Biosciences Limited |
Compositions and methods for treating diseases of protein aggregation involving ic3b deposition
|
|
HK1213788A1
(zh)
*
|
2012-10-12 |
2016-07-15 |
布里格姆及妇女医院股份有限公司 |
免疫應答的增强
|
|
WO2015075710A1
(en)
*
|
2013-11-25 |
2015-05-28 |
Ccam Biotherapeutics Ltd. |
Compositions comprising anti-ceacam1 antibodies, lymphocyte activating agents and activated lymphocytes for cancer therapy
|
|
PL3763387T3
(pl)
*
|
2013-11-25 |
2024-07-29 |
Famewave Ltd |
Kompozycje zawierające przeciwciała anty-ceacam1 i anty-pd do terapii nowotworu
|
|
WO2015101996A1
(en)
*
|
2014-01-02 |
2015-07-09 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Antibodies to ceacam1 and kinase inhibitors for treating braf-mutated cells
|
|
ES2755957T3
(es)
*
|
2014-03-31 |
2020-04-24 |
Univ Texas |
Anticuerpos de tos ferina humanizados y usos de los mismos
|