JP2021507877A5 - - Google Patents
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- JP2021507877A5 JP2021507877A5 JP2020528402A JP2020528402A JP2021507877A5 JP 2021507877 A5 JP2021507877 A5 JP 2021507877A5 JP 2020528402 A JP2020528402 A JP 2020528402A JP 2020528402 A JP2020528402 A JP 2020528402A JP 2021507877 A5 JP2021507877 A5 JP 2021507877A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- antibody
- hvr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2017/114247 | 2017-12-01 | ||
| PCT/CN2017/114247 WO2019104716A1 (en) | 2017-12-01 | 2017-12-01 | Methods for using cd137 ligand as biomarker for treatment with anti-cd137 antibody |
| PCT/CN2018/118631 WO2019105468A1 (en) | 2017-12-01 | 2018-11-30 | Methods for using cd137 ligand as a biomarker for treatment with anti-cd137 antibody |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021507877A JP2021507877A (ja) | 2021-02-25 |
| JP2021507877A5 true JP2021507877A5 (https=) | 2022-01-06 |
Family
ID=66664325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020528402A Pending JP2021507877A (ja) | 2017-12-01 | 2018-11-30 | Ｃｄ１３７リガンドを抗ｃｄ１３７抗体を用いた治療向けのバイオマーカーとして使用するための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200377608A1 (https=) |
| EP (1) | EP3717010A4 (https=) |
| JP (1) | JP2021507877A (https=) |
| CN (1) | CN111344014A (https=) |
| AU (1) | AU2018377751A1 (https=) |
| CA (1) | CA3079479A1 (https=) |
| SG (1) | SG11202004939SA (https=) |
| WO (2) | WO2019104716A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL268836B2 (en) | 2017-02-24 | 2024-04-01 | Macrogenics Inc | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
| CN111511762B (zh) | 2017-08-21 | 2025-05-06 | 天演药业公司 | 抗cd137分子及其用途 |
| WO2019148445A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| TWI841551B (zh) * | 2018-03-13 | 2024-05-11 | 瑞士商赫孚孟拉羅股份公司 | 使用靶向4-1bb (cd137)之促效劑的組合療法 |
| CR20200459A (es) * | 2018-04-13 | 2020-11-11 | Hoffmann La Roche | Moléculas de unión a antígeno dirigidas a her2 que comprendan 4-1bbl |
| AU2019312200B2 (en) | 2018-07-23 | 2024-11-14 | Heidelberg Pharma Research Gmbh | Use of anti-CD137 antibody drug conjugate (ADC) in allogeneic cell therapy |
| US20220411523A1 (en) * | 2019-11-13 | 2022-12-29 | Hefei Hankemab Biotechnology Co., Ltd | Molecule capable of binding to human 4-1bb and its application thereof |
| WO2021226883A1 (en) * | 2020-05-13 | 2021-11-18 | Adagene Ag | Compositions and methods for treating cancer submission of sequence listing on ascii text file |
| TW202200622A (zh) | 2020-05-13 | 2022-01-01 | 瑞士商天演藥業公司 | 用於治療癌症之組成物及方法 |
| CN116600805A (zh) * | 2020-06-23 | 2023-08-15 | 天演药业公司 | 包含抗cd137抗体的组合疗法 |
| GB202210957D0 (en) * | 2022-07-27 | 2022-09-07 | Alligator Bioscience Ab | Novel dosages |
| GB202210965D0 (en) * | 2022-07-27 | 2022-09-07 | Alligator Bioscience Ab | Novel dosages |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030118588A1 (en) * | 1999-05-22 | 2003-06-26 | Linda Diehl | Induction of anti-tumor CTL immunity through in vivo triggering of 4-1BB and/or CD40 |
| US20070253961A1 (en) * | 2004-06-09 | 2007-11-01 | Ulsan Industrial Education Foundation | Pharmaceutical Composition Comprising the Anti-4-1Bb Antibody for Treating or Preventing Rheumatoid Arthritis |
| RU2494107C2 (ru) * | 2005-05-09 | 2013-09-27 | Оно Фармасьютикал Ко., Лтд. | Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами |
| CN1294146C (zh) * | 2005-10-17 | 2007-01-10 | 山东大学 | 与t细胞表面共刺激分子cd137结合的多肽及其应用 |
| ES2336873B1 (es) * | 2007-11-07 | 2011-01-24 | Proyecto De Biomedicina Cima, S.L. | Composicion farmaceutica para el tratamiento de cancer. |
| EP3082839A4 (en) * | 2013-12-20 | 2017-08-09 | National University of Singapore | Differentiation therapy with cd137 ligand agonists |
| TW201632559A (zh) * | 2015-02-22 | 2016-09-16 | 索倫多醫療公司 | 結合ｃｄ１３７之抗體治療劑 |
| HRP20201022T1 (hr) * | 2015-09-22 | 2020-10-16 | Dingfu Biotarget Co., Ltd | Potpuno ljudsko antitijelo protiv ljudskog cd137 i njegova uporaba |
| WO2017106656A1 (en) * | 2015-12-17 | 2017-06-22 | Novartis Ag | Antibody molecules to pd-1 and uses thereof |
-
2017
- 2017-12-01 WO PCT/CN2017/114247 patent/WO2019104716A1/en not_active Ceased
-
2018
- 2018-11-30 AU AU2018377751A patent/AU2018377751A1/en not_active Abandoned
- 2018-11-30 CA CA3079479A patent/CA3079479A1/en active Pending
- 2018-11-30 US US16/768,500 patent/US20200377608A1/en not_active Abandoned
- 2018-11-30 SG SG11202004939SA patent/SG11202004939SA/en unknown
- 2018-11-30 CN CN201880073534.3A patent/CN111344014A/zh active Pending
- 2018-11-30 EP EP18883687.8A patent/EP3717010A4/en not_active Withdrawn
- 2018-11-30 JP JP2020528402A patent/JP2021507877A/ja active Pending
- 2018-11-30 WO PCT/CN2018/118631 patent/WO2019105468A1/en not_active Ceased
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