JP2019519492A5 - - Google Patents
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- JP2019519492A5 JP2019519492A5 JP2018558733A JP2018558733A JP2019519492A5 JP 2019519492 A5 JP2019519492 A5 JP 2019519492A5 JP 2018558733 A JP2018558733 A JP 2018558733A JP 2018558733 A JP2018558733 A JP 2018558733A JP 2019519492 A5 JP2019519492 A5 JP 2019519492A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662333643P | 2016-05-09 | 2016-05-09 | |
| US62/333,643 | 2016-05-09 | ||
| PCT/US2017/031791 WO2017196867A1 (en) | 2016-05-09 | 2017-05-09 | Anti-pd-l1 antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519492A JP2019519492A (ja) | 2019-07-11 |
| JP2019519492A5 true JP2019519492A5 (https=) | 2020-06-18 |
| JP6979971B2 JP6979971B2 (ja) | 2021-12-15 |
Family
ID=58710168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018558733A Active JP6979971B2 (ja) | 2016-05-09 | 2017-05-09 | 抗ｐｄ−ｌ１抗体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10954302B2 (https=) |
| EP (1) | EP3455257B1 (https=) |
| JP (1) | JP6979971B2 (https=) |
| KR (1) | KR102343742B1 (https=) |
| CN (1) | CN109311985B (https=) |
| AU (1) | AU2017264683B2 (https=) |
| CA (1) | CA3021669A1 (https=) |
| DK (1) | DK3455257T3 (https=) |
| ES (1) | ES2899361T3 (https=) |
| HU (1) | HUE055972T2 (https=) |
| IL (1) | IL262295B2 (https=) |
| PL (1) | PL3455257T3 (https=) |
| PT (1) | PT3455257T (https=) |
| SG (1) | SG11201809336QA (https=) |
| WO (1) | WO2017196867A1 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102389677B1 (ko) | 2013-03-15 | 2022-04-21 | 제넨테크, 인크. | Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법 |
| JP6721505B2 (ja) | 2013-09-05 | 2020-07-15 | アイジーエム バイオサイエンシズ インコーポレイテッド | 定常領域が修飾された（ｃｏｎｓｔａｎｔ ｃｈａｉｎ ｍｏｄｉｆｉｅｄ）二重特異性五価及び六価Ｉｇ−Ｍ抗体 |
| JP2017512208A (ja) | 2014-02-10 | 2017-05-18 | アイジーエム バイオサイエンス， インコーポレイテッド | ＩｇＡ多重特異性結合分子 |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| IL292311A (en) | 2014-04-03 | 2022-06-01 | Igm Biosciences Inc | J-chain qualified |
| PT3247728T (pt) | 2015-01-20 | 2020-07-16 | Igm Biosciences Inc | Moléculas de ligação do recetor da superfamília do fator de necrose tumoral (fnt) e utilização das mesmas |
| KR102357312B1 (ko) | 2015-03-04 | 2022-02-03 | 아이쥐엠 바이오사이언스 인코포레이티드 | Ｃｄ20 결합 분자 및 그의 용도 |
| CN108112254B (zh) | 2015-03-13 | 2022-01-28 | 西托姆克斯治疗公司 | 抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法 |
| WO2016154593A1 (en) | 2015-03-25 | 2016-09-29 | Igm Biosciences, Inc. | Multi-valent hepatitis b virus antigen binding molecules and uses thereof |
| WO2016168758A1 (en) | 2015-04-17 | 2016-10-20 | Igm Biosciences, Inc. | Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof |
| EP3824903A1 (en) | 2015-09-30 | 2021-05-26 | IGM Biosciences Inc. | Binding molecules with modified j-chain |
| EP3356401B1 (en) | 2015-09-30 | 2020-06-24 | IGM Biosciences, Inc. | Binding molecules with modified j-chain |
| JP6979971B2 (ja) * | 2016-05-09 | 2021-12-15 | アイジーエム バイオサイエンシズ インコーポレイテッド | 抗ｐｄ−ｌ１抗体 |
| US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| KR102726248B1 (ko) | 2016-07-07 | 2024-11-05 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 항체-애쥬번트 접합체 |
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| JP2020522486A (ja) | 2017-06-01 | 2020-07-30 | サイトメックス セラピューティクス インコーポレイテッド | 活性化可能抗ｐｄｌ１抗体、およびその使用方法 |
| CN111433224B (zh) | 2017-11-17 | 2024-03-19 | 南京传奇生物科技有限公司 | 抗pd-l1的单结构域抗体及其变体 |
| CN111356702B (zh) * | 2017-12-06 | 2022-07-26 | 正大天晴药业集团南京顺欣制药有限公司 | 抗pd-l1抗体及其抗原结合片段 |
| CN109970856B (zh) | 2017-12-27 | 2022-08-23 | 信达生物制药(苏州)有限公司 | 抗lag-3抗体及其用途 |
| EP3741777A4 (en) * | 2018-01-10 | 2021-10-13 | Jiangsu Hengrui Medicine Co., Ltd. | PD-L1 ANTIBODIES, ANTIGIBODY FRAGMENT THEREOF, AND PHARMACEUTICAL USE THEREOF |
| US11078283B2 (en) * | 2018-01-17 | 2021-08-03 | Apexigen, Inc. | Anti-PD-L1 antibodies and methods of use |
| CN111787951B (zh) | 2018-03-01 | 2025-06-17 | Igm生物科学股份有限公司 | 影响IgM血清半衰期的IgM Fc和J链突变 |
| TWI756621B (zh) * | 2019-01-25 | 2022-03-01 | 大陸商信達生物製藥（蘇州）有限公司 | 新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體 |
| WO2020169062A1 (zh) * | 2019-02-21 | 2020-08-27 | 祐和医药科技(北京)有限公司 | 抗pd-l1抗体及其用途 |
| AU2020241686A1 (en) | 2019-03-15 | 2021-11-04 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting HER2 |
| MX2022001934A (es) | 2019-08-15 | 2022-03-11 | Igm Biosciences Inc | Moleculas de union multimericas inmunoestimuladoras. |
| CN110746493A (zh) * | 2019-09-06 | 2020-02-04 | 中国药科大学 | 一种pd-l1拮抗剂多肽及其应用 |
| CN113121686B (zh) * | 2019-12-31 | 2025-12-02 | 迈威(上海)生物科技股份有限公司 | 抗pd-l1抗体及其应用 |
| BR112022017136A2 (pt) | 2020-02-28 | 2022-10-11 | Tallac Therapeutics Inc | Conjugação mediada por transglutaminase |
| BR112022021392A2 (pt) | 2020-04-22 | 2022-12-06 | Igm Biosciences Inc | Moléculas de ligação multiméricas de agonista de pd-1 |
| CN113754775A (zh) * | 2020-06-02 | 2021-12-07 | 三生国健药业（上海）股份有限公司 | 一种抗pd-l1和her2的双特异性抗体 |
| CN115916348A (zh) | 2020-06-18 | 2023-04-04 | 基因泰克公司 | 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗 |
| EP4188951A4 (en) * | 2020-07-27 | 2024-08-28 | IGM Biosciences, Inc. | Multimeric coronavirus binding molecules and uses thereof |
| KR20250140647A (ko) * | 2020-08-03 | 2025-09-25 | 난트셀, 인크. | Il-15 초작용제에 대한 약물-특이적 약동학 검정 |
| CN118871463A (zh) | 2021-07-28 | 2024-10-29 | 基因泰克公司 | 用于治疗癌症的方法和组合物 |
| TW202321308A (zh) | 2021-09-30 | 2023-06-01 | 美商建南德克公司 | 使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法 |
| CN113943371B (zh) * | 2021-11-01 | 2023-05-05 | 达石药业(广东)有限公司 | 一种抗her2/抗pd-l1双功能抗体及其应用 |
| WO2023178253A2 (en) * | 2022-03-18 | 2023-09-21 | Igm Biosciences, Inc. | Use of a multimeric anti-pd-l1 binding molecule in combination with a monoclonal antibody therapy |
| EP4537107A2 (en) | 2022-06-07 | 2025-04-16 | Genentech, Inc. | Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody |
| CN120603849A (zh) * | 2023-01-18 | 2025-09-05 | 科望(苏州)生物医药科技有限公司 | 抗pdl1单域抗体、融合蛋白及其用途 |
| WO2024160721A1 (en) | 2023-01-30 | 2024-08-08 | Kymab Limited | Antibodies |
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| JP6721505B2 (ja) | 2013-09-05 | 2020-07-15 | アイジーエム バイオサイエンシズ インコーポレイテッド | 定常領域が修飾された（ｃｏｎｓｔａｎｔ ｃｈａｉｎ ｍｏｄｉｆｉｅｄ）二重特異性五価及び六価Ｉｇ−Ｍ抗体 |
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| KR102357312B1 (ko) | 2015-03-04 | 2022-02-03 | 아이쥐엠 바이오사이언스 인코포레이티드 | Ｃｄ20 결합 분자 및 그의 용도 |
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| JP2019530640A (ja) | 2016-07-20 | 2019-10-24 | アイジーエム バイオサイエンシズ インコーポレイテッド | 多量体ｏｘ４０結合分子及びその使用 |
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| EP3487298A4 (en) | 2016-07-20 | 2020-03-11 | IGM Biosciences, Inc. | MULTIMERE CD137 / 4-1BB-BINDING MOLECULES AND USES THEREOF |
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2017
- 2017-05-09 JP JP2018558733A patent/JP6979971B2/ja active Active
- 2017-05-09 PL PL17724263T patent/PL3455257T3/pl unknown
- 2017-05-09 ES ES17724263T patent/ES2899361T3/es active Active
- 2017-05-09 KR KR1020187035104A patent/KR102343742B1/ko active Active
- 2017-05-09 CN CN201780027997.1A patent/CN109311985B/zh active Active
- 2017-05-09 DK DK17724263.3T patent/DK3455257T3/da active
- 2017-05-09 IL IL262295A patent/IL262295B2/en unknown
- 2017-05-09 AU AU2017264683A patent/AU2017264683B2/en not_active Ceased
- 2017-05-09 EP EP17724263.3A patent/EP3455257B1/en active Active
- 2017-05-09 HU HUE17724263A patent/HUE055972T2/hu unknown
- 2017-05-09 SG SG11201809336QA patent/SG11201809336QA/en unknown
- 2017-05-09 WO PCT/US2017/031791 patent/WO2017196867A1/en not_active Ceased
- 2017-05-09 CA CA3021669A patent/CA3021669A1/en active Pending
- 2017-05-09 US US16/098,479 patent/US10954302B2/en active Active
- 2017-05-09 PT PT177242633T patent/PT3455257T/pt unknown
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2021
- 2021-02-10 US US17/172,790 patent/US20210163600A1/en not_active Abandoned
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2023
- 2023-09-07 US US18/463,194 patent/US20240002514A1/en active Pending
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