JP2017519501A5 - - Google Patents
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- Publication number
- JP2017519501A5 JP2017519501A5 JP2016573833A JP2016573833A JP2017519501A5 JP 2017519501 A5 JP2017519501 A5 JP 2017519501A5 JP 2016573833 A JP2016573833 A JP 2016573833A JP 2016573833 A JP2016573833 A JP 2016573833A JP 2017519501 A5 JP2017519501 A5 JP 2017519501A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- axl
- domain
- seq
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1410826.0 | 2014-06-18 | ||
| GBGB1410826.0A GB201410826D0 (en) | 2014-06-18 | 2014-06-18 | Anti-axl antibodies |
| PCT/EP2015/063700 WO2015193428A1 (en) | 2014-06-18 | 2015-06-18 | Anti-axl antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519501A JP2017519501A (ja) | 2017-07-20 |
| JP2017519501A5 true JP2017519501A5 (cg-RX-API-DMAC7.html) | 2018-05-10 |
| JP6787795B2 JP6787795B2 (ja) | 2020-11-18 |
Family
ID=51266761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573833A Active JP6787795B2 (ja) | 2014-06-18 | 2015-06-18 | 抗Ａｘｌ抗体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9975954B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3157559B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6787795B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102453226B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN113563471B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015276153B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2952296A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3157559T3 (cg-RX-API-DMAC7.html) |
| GB (1) | GB201410826D0 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20201091T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE049755T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT3157559T (cg-RX-API-DMAC7.html) |
| MX (1) | MX388222B (cg-RX-API-DMAC7.html) |
| SI (1) | SI3157559T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015193428A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201410825D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| GB201410826D0 (en) * | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| JP6864953B2 (ja) * | 2014-12-09 | 2021-04-28 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Ａｘｌに対するヒトモノクローナル抗体 |
| JP6931609B2 (ja) * | 2014-12-18 | 2021-09-08 | ベルゲン テクノロジオーヴァーフォリング エイエス | 抗Ａｘｌアンタゴニスト抗体 |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201509338D0 (en) * | 2015-05-29 | 2015-07-15 | Bergenbio As | Combination therapy |
| GB201610902D0 (en) | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
| PL3544636T3 (pl) * | 2017-02-08 | 2021-12-06 | Adc Therapeutics Sa | Koniugaty pirolobenzodiazepina-przeciwciało |
| WO2019219612A1 (en) | 2018-05-14 | 2019-11-21 | Bergenbio Asa | Serum biomarkers |
| CN110540592B (zh) * | 2018-05-29 | 2022-08-09 | 杭州尚健生物技术有限公司 | 结合axl蛋白的抗体及其应用 |
| US20220177593A1 (en) * | 2019-03-29 | 2022-06-09 | Celldex Therapeutics, Inc. | Anti-axl antibodies and methods of use thereof |
| GB201912059D0 (en) | 2019-08-22 | 2019-10-09 | Bergenbio As | Combaination therapy of a patient subgroup |
| CN113045664B (zh) * | 2019-11-28 | 2023-05-12 | 尚健单抗（北京）生物技术有限公司 | 一种分离的结合抗原axl的蛋白及其用途 |
| WO2021154156A1 (en) * | 2020-01-31 | 2021-08-05 | Agency For Science, Technology And Research | Anti-axl antibody and uses thereof |
| GB202004189D0 (en) | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
| IL297132A (en) | 2020-04-08 | 2022-12-01 | Bergenbio Asa | axl inhibitors for antiviral therapy |
| GB202006072D0 (en) | 2020-04-24 | 2020-06-10 | Bergenbio Asa | Method of selecting patients for treatment with cmbination therapy |
| JP2024505935A (ja) | 2021-01-29 | 2024-02-08 | イリミス セラピューティクス インコーポレーテッド | 非炎症性食細胞作用誘導活性を有する融合分子 |
| GB202104037D0 (en) | 2021-03-23 | 2021-05-05 | Bergenbio Asa | Combination therapy |
| IL289525B2 (en) * | 2021-12-30 | 2023-03-01 | B G Negev Technologies And Applications Ltd At Ben Gurion Univ | Conjugated antibodies for cancer treatment |
| WO2024145869A1 (en) * | 2023-01-05 | 2024-07-11 | Zhejiang Shimai Pharmaceutical Co., Ltd. | Antibodies against axl and uses thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| CL2007002668A1 (es) * | 2006-09-20 | 2008-05-09 | Amgen Inc | Proteina de union a antigeno que se une al receptor de glucagon humano; acido nucleico que la codifica; metodo de produccion; composicion farmaceutica que la comprende; y su uso para tratar o prevenir la diabetes tipo 2. |
| SG186000A1 (en) * | 2007-11-12 | 2012-12-28 | U3 Pharma Gmbh | Axl antibodies |
| TW200936160A (en) | 2007-11-15 | 2009-09-01 | Chugai Pharmaceutical Co Ltd | Monoclonal antibodies that bind to anexelekto and uses thereof |
| EP2198884A1 (en) * | 2008-12-18 | 2010-06-23 | Centre National de la Recherche Scientifique (CNRS) | Monoclonal antibodies directed against LG4-5 domain of alpha3 chain of human laminin-5 |
| EP2270053A1 (en) * | 2009-05-11 | 2011-01-05 | U3 Pharma GmbH | Humanized AXL antibodies |
| WO2010131733A1 (ja) | 2009-05-15 | 2010-11-18 | 中外製薬株式会社 | 抗axl抗体 |
| AR077595A1 (es) | 2009-07-27 | 2011-09-07 | Genentech Inc | Tratamientos de combinacion |
| RU2577986C2 (ru) * | 2010-06-18 | 2016-03-20 | Дженентек, Инк. | Антитела против axl и способы их применения |
| CA2839480A1 (en) * | 2011-06-22 | 2012-12-27 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Anti-axl antibodies and uses thereof |
| US9249228B2 (en) * | 2011-06-22 | 2016-02-02 | Oribase Pharma | Anti-Axl antibodies and uses thereof |
| EP2589609A1 (en) | 2011-11-03 | 2013-05-08 | Pierre Fabre Medicament | Antigen binding protein and its use as addressing product for the treatment of cancer |
| GB201410825D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| GB201410826D0 (en) * | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| JP6931609B2 (ja) * | 2014-12-18 | 2021-09-08 | ベルゲン テクノロジオーヴァーフォリング エイエス | 抗Ａｘｌアンタゴニスト抗体 |
| GB201506411D0 (en) * | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| PL3612234T3 (pl) * | 2017-04-20 | 2024-09-02 | Adc Therapeutics Sa | Terapia skojarzona z koniugatem anty-AXL przeciwciało-lek |
-
2014
- 2014-06-18 GB GBGB1410826.0A patent/GB201410826D0/en not_active Ceased
-
2015
- 2015-06-18 HR HRP20201091TT patent/HRP20201091T1/hr unknown
- 2015-06-18 WO PCT/EP2015/063700 patent/WO2015193428A1/en not_active Ceased
- 2015-06-18 AU AU2015276153A patent/AU2015276153B2/en active Active
- 2015-06-18 US US15/318,028 patent/US9975954B2/en active Active
- 2015-06-18 LT LTEP15729504.9T patent/LT3157559T/lt unknown
- 2015-06-18 SI SI201531303T patent/SI3157559T1/sl unknown
- 2015-06-18 KR KR1020177001482A patent/KR102453226B1/ko active Active
- 2015-06-18 EP EP15729504.9A patent/EP3157559B1/en active Active
- 2015-06-18 JP JP2016573833A patent/JP6787795B2/ja active Active
- 2015-06-18 CA CA2952296A patent/CA2952296A1/en active Pending
- 2015-06-18 CN CN202110689921.3A patent/CN113563471B/zh active Active
- 2015-06-18 MX MX2016016883A patent/MX388222B/es unknown
- 2015-06-18 HU HUE15729504A patent/HUE049755T2/hu unknown
- 2015-06-18 DK DK15729504.9T patent/DK3157559T3/da active
- 2015-06-18 CN CN201580042717.5A patent/CN106573979B/zh active Active
-
2018
- 2018-04-20 US US15/958,076 patent/US11186643B2/en active Active
-
2021
- 2021-10-18 US US17/503,568 patent/US20220185897A1/en not_active Abandoned