JP2017515867A5 - - Google Patents

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Publication number
JP2017515867A5
JP2017515867A5 JP2016568391A JP2016568391A JP2017515867A5 JP 2017515867 A5 JP2017515867 A5 JP 2017515867A5 JP 2016568391 A JP2016568391 A JP 2016568391A JP 2016568391 A JP2016568391 A JP 2016568391A JP 2017515867 A5 JP2017515867 A5 JP 2017515867A5
Authority
JP
Japan
Prior art keywords
hapten
following formula
nicotine
antigen
carrier conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016568391A
Other languages
English (en)
Japanese (ja)
Other versions
JP6564396B2 (ja
JP2017515867A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/031583 external-priority patent/WO2015179403A1/en
Publication of JP2017515867A publication Critical patent/JP2017515867A/ja
Publication of JP2017515867A5 publication Critical patent/JP2017515867A5/ja
Application granted granted Critical
Publication of JP6564396B2 publication Critical patent/JP6564396B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016568391A 2014-05-19 2015-05-19 ニコチンワクチン開発のためのエナンチオピュアなハプテン Expired - Fee Related JP6564396B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462000312P 2014-05-19 2014-05-19
US62/000,312 2014-05-19
PCT/US2015/031583 WO2015179403A1 (en) 2014-05-19 2015-05-19 Enantiopure haptens for nicotine vaccine development

Publications (3)

Publication Number Publication Date
JP2017515867A JP2017515867A (ja) 2017-06-15
JP2017515867A5 true JP2017515867A5 (https=) 2018-06-28
JP6564396B2 JP6564396B2 (ja) 2019-08-21

Family

ID=54554631

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016568391A Expired - Fee Related JP6564396B2 (ja) 2014-05-19 2015-05-19 ニコチンワクチン開発のためのエナンチオピュアなハプテン

Country Status (8)

Country Link
US (3) US20170107275A1 (https=)
EP (1) EP3145920B1 (https=)
JP (1) JP6564396B2 (https=)
KR (1) KR102435658B1 (https=)
CN (2) CN110452217B (https=)
AU (1) AU2015264325B2 (https=)
CA (1) CA2949667C (https=)
WO (1) WO2015179403A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170107275A1 (en) 2014-05-19 2017-04-20 The Scripps Research Institute Enantiopure haptens for nicotine vaccine development
CN118161604B (zh) * 2024-03-25 2025-01-14 海南大学 一种尼古丁蛋白缀合物、其制备方法及在疫苗中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
SE9801923D0 (sv) * 1998-05-29 1998-05-29 Independent Pharmaceutical Ab Nicotine vaccine
US6232082B1 (en) * 1998-12-01 2001-05-15 Nabi Hapten-carrier conjugates for treating and preventing nicotine addiction
EP1963308A4 (en) * 2005-11-28 2010-12-15 Nabi Biopharmaceuticals METHOD FOR PRODUCING A NICOTINE HAPTEN
WO2007100755A1 (en) * 2006-02-27 2007-09-07 Nabi Biopharmaceuticals Method for decreasing the toxic effects of nicotine on fetuses in pregnant women
US7820826B2 (en) * 2006-03-29 2010-10-26 North Carolina State University Synthesis and regioselective substitution of 6-halo-and 6-alkoxy nicotine derivatives
TWI578997B (zh) * 2010-06-04 2017-04-21 輝瑞疫苗有限責任公司 用於預防或治療菸鹼成癮之共軛體
US20170107275A1 (en) 2014-05-19 2017-04-20 The Scripps Research Institute Enantiopure haptens for nicotine vaccine development
US9884114B2 (en) * 2015-06-23 2018-02-06 Arizona Board Of Regents On Behalf Of Arizona State University Methods of rational nicotine hapten design and uses thereof

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