JP2017514875A5 - - Google Patents
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- Publication number
- JP2017514875A5 JP2017514875A5 JP2016566943A JP2016566943A JP2017514875A5 JP 2017514875 A5 JP2017514875 A5 JP 2017514875A5 JP 2016566943 A JP2016566943 A JP 2016566943A JP 2016566943 A JP2016566943 A JP 2016566943A JP 2017514875 A5 JP2017514875 A5 JP 2017514875A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- sphincter
- composition according
- sdf
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000005070 sphincter Anatomy 0.000 claims description 28
- 102000006573 Chemokine CXCL12 Human genes 0.000 claims description 25
- 108010008951 Chemokine CXCL12 Proteins 0.000 claims description 25
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 9
- 239000007924 injection Substances 0.000 claims description 9
- 206010021639 Incontinence Diseases 0.000 claims description 8
- 239000013598 vector Substances 0.000 claims description 7
- 210000002027 skeletal muscle Anatomy 0.000 claims description 6
- 210000002460 smooth muscle Anatomy 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000002708 enhancing effect Effects 0.000 claims description 4
- 150000007523 nucleic acids Chemical class 0.000 claims description 3
- 102000039446 nucleic acids Human genes 0.000 claims description 3
- 108020004707 nucleic acids Proteins 0.000 claims description 3
- 102000008186 Collagen Human genes 0.000 claims description 2
- 108010035532 Collagen Proteins 0.000 claims description 2
- 208000018522 Gastrointestinal disease Diseases 0.000 claims description 2
- 208000000921 Urge Urinary Incontinence Diseases 0.000 claims description 2
- 206010046543 Urinary incontinence Diseases 0.000 claims description 2
- 239000008365 aqueous carrier Substances 0.000 claims description 2
- 229920001436 collagen Polymers 0.000 claims description 2
- 208000010643 digestive system disease Diseases 0.000 claims description 2
- 230000002496 gastric effect Effects 0.000 claims description 2
- 208000018685 gastrointestinal system disease Diseases 0.000 claims description 2
- 239000007972 injectable composition Substances 0.000 claims description 2
- 230000000968 intestinal effect Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 230000002085 persistent effect Effects 0.000 claims description 2
- 239000013600 plasmid vector Substances 0.000 claims description 2
- 206010046494 urge incontinence Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 230000007812 deficiency Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 19
- 239000003814 drug Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461990190P | 2014-05-08 | 2014-05-08 | |
| US61/990,190 | 2014-05-08 | ||
| PCT/US2015/028490 WO2015171417A1 (en) | 2014-05-08 | 2015-04-30 | Methods of treating incontinence and other sphincter deficiency disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017514875A JP2017514875A (ja) | 2017-06-08 |
| JP2017514875A5 true JP2017514875A5 (enExample) | 2018-06-14 |
Family
ID=54392862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566943A Pending JP2017514875A (ja) | 2014-05-08 | 2015-04-30 | 失禁および他の括約筋不全障害を処置する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10420818B2 (enExample) |
| EP (1) | EP3139945B1 (enExample) |
| JP (1) | JP2017514875A (enExample) |
| AU (1) | AU2015256383B2 (enExample) |
| CA (1) | CA2946761C (enExample) |
| WO (1) | WO2015171417A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3139945B1 (en) | 2014-05-08 | 2025-08-27 | Wake Forest University Health Sciences | Methods of treating incontinence and other sphincter deficiency disorders |
| EP3600251A4 (en) | 2017-03-30 | 2021-01-13 | Wake Forest University Health Sciences | KIDNEY DISEASE TREATMENT METHODS |
| WO2019032930A1 (en) * | 2017-08-11 | 2019-02-14 | Wake Forest University Health Sciences | USE OF CXCL12 FOR THERAPY AFTER SURGERY OF THE PROSTATE |
| CN114159471A (zh) * | 2020-09-11 | 2022-03-11 | 永立荣生医股份有限公司 | 包括羊水干细胞球的医药组合物及其治疗尿失禁的用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US311219A (en) | 1885-01-27 | Mechanical toy | ||
| JP2609851B2 (ja) * | 1986-09-04 | 1997-05-14 | 悦子 柿崎 | 徐放性注射剤 |
| US5385561A (en) | 1994-01-18 | 1995-01-31 | Bard International, Inc. | Apparatus and method for injecting a viscous material into the tissue of a patient |
| DE4414755C2 (de) * | 1994-04-27 | 2000-11-16 | Lohmann Therapie Syst Lts | Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung |
| US5588960A (en) | 1994-12-01 | 1996-12-31 | Vidamed, Inc. | Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence |
| US5925629A (en) | 1997-10-28 | 1999-07-20 | Vivus, Incorporated | Transurethral administration of androgenic agents for the treatment of erectile dysfunction |
| CA2412436C (en) | 2000-06-05 | 2013-05-21 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
| US7015253B2 (en) | 2001-07-10 | 2006-03-21 | American Medical Systems, Inc. | Regimen for treating prostate tissue and surgical kit for use in the regimen |
| ES2645012T3 (es) | 2004-09-24 | 2017-12-01 | Mesoblast, Inc. | Método para potenciar la proliferación y/o supervivencia de las células precursoras mesenquimales (MPC) |
| EP1996013A4 (en) * | 2005-09-21 | 2010-03-10 | Dask Technologies Llc | METHODS AND COMPOSITIONS FOR FUNCTIONALITY OF ORGANS AND TISSUES |
| CA2640087A1 (en) | 2006-01-25 | 2007-08-02 | Mount Sinai School Of Medicine | Methods and compositions for modulating the mobilization of stem cells |
| US7598028B2 (en) | 2006-11-28 | 2009-10-06 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating prostate disorders |
| EP2155216A1 (en) * | 2007-06-15 | 2010-02-24 | Ethicon, Inc | Tissue fragment compositions for the treatment of incontinence |
| ATE543507T1 (de) * | 2007-11-07 | 2012-02-15 | Ono Pharmaceutical Co | Sdf-1 enthaltende zusammensetzung mit anhaltender freisetzung |
| WO2009079451A2 (en) * | 2007-12-14 | 2009-06-25 | The Cleveland Clinic Foundation | Compositions and methods of promoting wound healing |
| JP5908279B2 (ja) | 2008-08-09 | 2016-04-26 | マサチューセッツ インスチテュート オブ テクノロジーＭａｓｓａｃｈｕｓｅｔｔｓ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ | 移植可能な薬物送達デバイス並びに男性の尿生殖器及び周囲組織を治療する方法 |
| CN102740894B (zh) | 2009-08-28 | 2015-07-15 | 克利夫兰临床医学基金会 | 用于治疗缺血组织的sdf-1递送 |
| US9308277B2 (en) * | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| EP3139945B1 (en) | 2014-05-08 | 2025-08-27 | Wake Forest University Health Sciences | Methods of treating incontinence and other sphincter deficiency disorders |
-
2015
- 2015-04-30 EP EP15789938.6A patent/EP3139945B1/en active Active
- 2015-04-30 AU AU2015256383A patent/AU2015256383B2/en active Active
- 2015-04-30 WO PCT/US2015/028490 patent/WO2015171417A1/en not_active Ceased
- 2015-04-30 CA CA2946761A patent/CA2946761C/en active Active
- 2015-04-30 JP JP2016566943A patent/JP2017514875A/ja active Pending
- 2015-04-30 US US15/309,093 patent/US10420818B2/en active Active
-
2019
- 2019-08-15 US US16/541,202 patent/US11160848B2/en active Active
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