JP2017514875A5 - - Google Patents
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- Publication number
- JP2017514875A5 JP2017514875A5 JP2016566943A JP2016566943A JP2017514875A5 JP 2017514875 A5 JP2017514875 A5 JP 2017514875A5 JP 2016566943 A JP2016566943 A JP 2016566943A JP 2016566943 A JP2016566943 A JP 2016566943A JP 2017514875 A5 JP2017514875 A5 JP 2017514875A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- sphincter
- composition according
- sdf
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000005070 sphincter Anatomy 0.000 claims description 28
- 102000006573 Chemokine CXCL12 Human genes 0.000 claims description 25
- 108010008951 Chemokine CXCL12 Proteins 0.000 claims description 25
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 9
- 239000007924 injection Substances 0.000 claims description 9
- 206010021639 Incontinence Diseases 0.000 claims description 8
- 239000013598 vector Substances 0.000 claims description 7
- 210000002027 skeletal muscle Anatomy 0.000 claims description 6
- 210000002460 smooth muscle Anatomy 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000002708 enhancing effect Effects 0.000 claims description 4
- 150000007523 nucleic acids Chemical class 0.000 claims description 3
- 102000039446 nucleic acids Human genes 0.000 claims description 3
- 108020004707 nucleic acids Proteins 0.000 claims description 3
- 102000008186 Collagen Human genes 0.000 claims description 2
- 108010035532 Collagen Proteins 0.000 claims description 2
- 208000018522 Gastrointestinal disease Diseases 0.000 claims description 2
- 208000000921 Urge Urinary Incontinence Diseases 0.000 claims description 2
- 206010046543 Urinary incontinence Diseases 0.000 claims description 2
- 239000008365 aqueous carrier Substances 0.000 claims description 2
- 229920001436 collagen Polymers 0.000 claims description 2
- 208000010643 digestive system disease Diseases 0.000 claims description 2
- 230000002496 gastric effect Effects 0.000 claims description 2
- 208000018685 gastrointestinal system disease Diseases 0.000 claims description 2
- 239000007972 injectable composition Substances 0.000 claims description 2
- 230000000968 intestinal effect Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 230000002085 persistent effect Effects 0.000 claims description 2
- 239000013600 plasmid vector Substances 0.000 claims description 2
- 206010046494 urge incontinence Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 230000007812 deficiency Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 19
- 239000003814 drug Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461990190P | 2014-05-08 | 2014-05-08 | |
| US61/990,190 | 2014-05-08 | ||
| PCT/US2015/028490 WO2015171417A1 (en) | 2014-05-08 | 2015-04-30 | Methods of treating incontinence and other sphincter deficiency disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017514875A JP2017514875A (ja) | 2017-06-08 |
| JP2017514875A5 true JP2017514875A5 (enExample) | 2018-06-14 |
Family
ID=54392862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566943A Pending JP2017514875A (ja) | 2014-05-08 | 2015-04-30 | 失禁および他の括約筋不全障害を処置する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10420818B2 (enExample) |
| EP (1) | EP3139945B1 (enExample) |
| JP (1) | JP2017514875A (enExample) |
| AU (1) | AU2015256383B2 (enExample) |
| CA (1) | CA2946761C (enExample) |
| WO (1) | WO2015171417A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3139945B1 (en) | 2014-05-08 | 2025-08-27 | Wake Forest University Health Sciences | Methods of treating incontinence and other sphincter deficiency disorders |
| AU2018244776B2 (en) | 2017-03-30 | 2023-12-14 | Wake Forest University Health Sciences | Methods of treatment for kidney disease |
| WO2019032930A1 (en) * | 2017-08-11 | 2019-02-14 | Wake Forest University Health Sciences | USE OF CXCL12 FOR THERAPY AFTER SURGERY OF THE PROSTATE |
| CN114159471A (zh) * | 2020-09-11 | 2022-03-11 | 永立荣生医股份有限公司 | 包括羊水干细胞球的医药组合物及其治疗尿失禁的用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US311219A (en) | 1885-01-27 | Mechanical toy | ||
| JP2609851B2 (ja) | 1986-09-04 | 1997-05-14 | 悦子 柿崎 | 徐放性注射剤 |
| US5385561A (en) | 1994-01-18 | 1995-01-31 | Bard International, Inc. | Apparatus and method for injecting a viscous material into the tissue of a patient |
| DE4414755C2 (de) * | 1994-04-27 | 2000-11-16 | Lohmann Therapie Syst Lts | Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung |
| US5588960A (en) | 1994-12-01 | 1996-12-31 | Vidamed, Inc. | Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence |
| US5925629A (en) | 1997-10-28 | 1999-07-20 | Vivus, Incorporated | Transurethral administration of androgenic agents for the treatment of erectile dysfunction |
| MXPA02012067A (es) | 2000-06-05 | 2004-08-19 | Univ Columbia | Identificacion y uso de celulas endoteliales precursoras derivadas de medula osea par mejorar la funcion del miocardio despues de dano isquemico. |
| WO2003005889A2 (en) | 2001-07-10 | 2003-01-23 | Ams Research Corporation | Surgical kit for treating prostate tissue |
| JP2008514188A (ja) * | 2004-09-24 | 2008-05-08 | アンジオブラスト システムズ，インコーポレーテッド | 間葉系前駆細胞（ｍｐｃ）の増殖および／または生存を増強させる方法 |
| AU2006292203A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| WO2007087367A2 (en) | 2006-01-25 | 2007-08-02 | Mount Sinai School Of Medicine | Methods and compositions for modulating the mobilization of stem cells |
| US7598028B2 (en) | 2006-11-28 | 2009-10-06 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating prostate disorders |
| EP2155216A1 (en) * | 2007-06-15 | 2010-02-24 | Ethicon, Inc | Tissue fragment compositions for the treatment of incontinence |
| EP2218459B1 (en) | 2007-11-07 | 2012-02-01 | Ono Pharmaceutical Co., Ltd. | Sustained release composition containing sdf-1 |
| US20100272679A1 (en) * | 2007-12-14 | 2010-10-28 | Penn Marc S | Compositions and methods of promoting wound healing |
| CA2733468C (en) | 2008-08-09 | 2017-12-05 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues |
| WO2011026041A2 (en) | 2009-08-28 | 2011-03-03 | The Cleveland Clinic Foundation | Sdf-1 delivery for treating ischemic tissue |
| US9308277B2 (en) * | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| EP3139945B1 (en) | 2014-05-08 | 2025-08-27 | Wake Forest University Health Sciences | Methods of treating incontinence and other sphincter deficiency disorders |
-
2015
- 2015-04-30 EP EP15789938.6A patent/EP3139945B1/en active Active
- 2015-04-30 US US15/309,093 patent/US10420818B2/en active Active
- 2015-04-30 WO PCT/US2015/028490 patent/WO2015171417A1/en not_active Ceased
- 2015-04-30 JP JP2016566943A patent/JP2017514875A/ja active Pending
- 2015-04-30 CA CA2946761A patent/CA2946761C/en active Active
- 2015-04-30 AU AU2015256383A patent/AU2015256383B2/en active Active
-
2019
- 2019-08-15 US US16/541,202 patent/US11160848B2/en active Active
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