JP2017512200A5 - - Google Patents
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- Publication number
- JP2017512200A5 JP2017512200A5 JP2016553811A JP2016553811A JP2017512200A5 JP 2017512200 A5 JP2017512200 A5 JP 2017512200A5 JP 2016553811 A JP2016553811 A JP 2016553811A JP 2016553811 A JP2016553811 A JP 2016553811A JP 2017512200 A5 JP2017512200 A5 JP 2017512200A5
- Authority
- JP
- Japan
- Prior art keywords
- htlv
- antigen
- antibody
- detecting
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 38
- 102000036639 antigens Human genes 0.000 claims 38
- 108091007433 antigens Proteins 0.000 claims 38
- 241000598436 Human T-cell lymphotropic virus Species 0.000 claims 36
- 239000000203 mixture Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 230000008105 immune reaction Effects 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical group N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 239000011541 reaction mixture Substances 0.000 claims 4
- 108010006519 Molecular Chaperones Proteins 0.000 claims 3
- 210000001124 body fluid Anatomy 0.000 claims 3
- 239000010839 body fluid Substances 0.000 claims 3
- 239000000047 product Substances 0.000 claims 3
- 239000007790 solid phase Substances 0.000 claims 3
- 239000012327 Ruthenium complex Substances 0.000 claims 2
- 101800000385 Transmembrane protein Proteins 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000012636 effector Substances 0.000 claims 2
- 239000007791 liquid phase Substances 0.000 claims 2
- 102000053602 DNA Human genes 0.000 claims 1
- 108020004511 Recombinant DNA Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14157165.3A EP2913338A1 (en) | 2014-02-28 | 2014-02-28 | Soluable and immunoreactive variants of HTLV capsid antigen p24 |
| EP14157165.3 | 2014-02-28 | ||
| PCT/EP2015/053966 WO2015128394A2 (en) | 2014-02-28 | 2015-02-26 | Soluble and immunoreactive variants of htlv capsid antigen p24 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017512200A JP2017512200A (ja) | 2017-05-18 |
| JP2017512200A5 true JP2017512200A5 (enExample) | 2017-10-26 |
| JP6491228B2 JP6491228B2 (ja) | 2019-03-27 |
Family
ID=50184798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553811A Active JP6491228B2 (ja) | 2014-02-28 | 2015-02-26 | ＨＴＬＶキャプシド抗原ｐ２４の可溶性かつ免疫反応性バリアント |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10466242B2 (enExample) |
| EP (2) | EP2913338A1 (enExample) |
| JP (1) | JP6491228B2 (enExample) |
| CN (1) | CN106029687B (enExample) |
| CA (1) | CA2938712C (enExample) |
| ES (1) | ES2662611T3 (enExample) |
| WO (1) | WO2015128394A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3427057A1 (en) | 2016-03-07 | 2019-01-16 | H. Hoffnabb-La Roche Ag | Detection of anti-p53 antibodies |
| CN112352055A (zh) * | 2018-02-26 | 2021-02-09 | 艾恩德霍芬技术大学 | 用于检测和定量溶液中的生物分子或配体的生物发光生物传感器 |
| CN115843334A (zh) * | 2020-04-23 | 2023-03-24 | 豪夫迈·罗氏有限公司 | 用于抗体免疫测定的冠状核衣壳抗原 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2564268B2 (ja) * | 1985-08-28 | 1996-12-18 | 協和醗酵工業株式会社 | 融合抗原ポリペプチド |
| NZ238855A (en) | 1990-07-18 | 1994-03-25 | Iaf Biochem Int | Peptides, mixtures thereof and compositions useful for detecting htlv-i and htlv-ii infections |
| CA2117378C (en) * | 1992-02-24 | 2003-04-15 | Steven K. H. Foung | Htlv-i/htlv-ii assay and method |
| CA2223235A1 (en) * | 1995-06-05 | 1996-12-12 | Abbott Laboratories | Detection of htlv antibodies utilizing recombinant proteins |
| EP0928336A1 (en) | 1996-09-26 | 1999-07-14 | Medical Research Council | Chaperone fragments |
| JP2000078973A (ja) * | 1998-09-03 | 2000-03-21 | Tonen Corp | Ｈｔｌｖ−ｉ組換え抗原 |
| WO2001010457A2 (en) * | 1999-08-09 | 2001-02-15 | Tripep Ab | Pharmaceutical compositions containing tripeptides |
| US6258932B1 (en) * | 1999-08-09 | 2001-07-10 | Tripep Ab | Peptides that block viral infectivity and methods of use thereof |
| JP4262594B2 (ja) | 2001-06-22 | 2009-05-13 | エフ．ホフマン−ラ ロシュ アーゲー | レトロウイルス表面糖タンパク質を含む可溶性複合体 |
| PL2112158T3 (pl) * | 2007-04-20 | 2012-03-30 | Hoffmann La Roche | Wykrywanie pierwotnych infekcji wywołanych patogenami |
| EP2127678A1 (en) * | 2008-05-26 | 2009-12-02 | Roche Diagnostics GmbH | SlpA as a tool for recombinant protein and enzyme technology |
-
2014
- 2014-02-28 EP EP14157165.3A patent/EP2913338A1/en not_active Ceased
-
2015
- 2015-02-26 CA CA2938712A patent/CA2938712C/en active Active
- 2015-02-26 WO PCT/EP2015/053966 patent/WO2015128394A2/en not_active Ceased
- 2015-02-26 EP EP15706804.0A patent/EP3110831B1/en active Active
- 2015-02-26 CN CN201580010787.2A patent/CN106029687B/zh active Active
- 2015-02-26 ES ES15706804.0T patent/ES2662611T3/es active Active
- 2015-02-26 JP JP2016553811A patent/JP6491228B2/ja active Active
-
2016
- 2016-08-25 US US15/246,607 patent/US10466242B2/en active Active
-
2019
- 2019-09-20 US US16/577,175 patent/US11567079B2/en active Active
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