JP2017511751A5 - - Google Patents
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- Publication number
- JP2017511751A5 JP2017511751A5 JP2016569012A JP2016569012A JP2017511751A5 JP 2017511751 A5 JP2017511751 A5 JP 2017511751A5 JP 2016569012 A JP2016569012 A JP 2016569012A JP 2016569012 A JP2016569012 A JP 2016569012A JP 2017511751 A5 JP2017511751 A5 JP 2017511751A5
- Authority
- JP
- Japan
- Prior art keywords
- ultrafiltration
- capillary
- unit
- product stream
- module
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000108 ultra-filtration Methods 0.000 claims 12
- 239000012530 fluid Substances 0.000 claims 6
- 229960000074 biopharmaceutical Drugs 0.000 claims 3
- 229920002521 macromolecule Polymers 0.000 claims 3
- 238000005406 washing Methods 0.000 claims 3
- 238000004140 cleaning Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14155338.8 | 2014-02-17 | ||
| EP14155338.8A EP2907565A1 (de) | 2014-02-17 | 2014-02-17 | Dialyse-Einheit zum kontinuierlichen Puffer- bzw. Medienaustausch aus einer Proteinlösung |
| PCT/EP2015/053060 WO2015121403A1 (de) | 2014-02-17 | 2015-02-13 | Ultrafiltrationsunit zum kontinuierlichen puffer- bzw. medienaustausch aus einer proteinlösung. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017511751A JP2017511751A (ja) | 2017-04-27 |
| JP2017511751A5 true JP2017511751A5 (cg-RX-API-DMAC7.html) | 2017-11-16 |
| JP6605504B2 JP6605504B2 (ja) | 2019-11-13 |
Family
ID=50115700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016569012A Expired - Fee Related JP6605504B2 (ja) | 2014-02-17 | 2015-02-13 | タンパク質溶液からバッファーまたは媒体を連続的に交換するための限外ろ過ユニット |
Country Status (18)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015195452A2 (en) | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Single-pass filtration systems and processes |
| WO2015195453A2 (en) | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Methods for increasing the capacity of flow-through processes |
| KR102064888B1 (ko) | 2014-06-25 | 2020-01-10 | 이엠디 밀리포어 코포레이션 | 밀집한 나권형 필터 엘리먼트, 모듈 및 시스템 |
| ES2926043T3 (es) | 2014-08-29 | 2022-10-21 | Emd Millipore Corp | Sistemas de filtración de flujo tangencial de paso único y sistemas de filtración de flujo tangencial con recirculación de retenido |
| SG10202006102UA (en) | 2014-08-29 | 2020-07-29 | Emd Millipore Corp | Processes For Filtering Liquids Using Single Pass Tangential Flow Filtration Systems AndTangential Flow Filtration Systems With Recirculation of Retentate |
| WO2017029307A1 (en) * | 2015-08-20 | 2017-02-23 | Ge Healthcare Bio-Sciences Ab | Improved method for enhancing filtration yields in tangential flow filtration system |
| WO2017213892A1 (en) | 2016-06-09 | 2017-12-14 | Emd Millipore Corporation | Radial-path filter elements, systems and methods of using same |
| WO2018013135A1 (en) | 2016-07-15 | 2018-01-18 | Hewlett-Packard Development Company, L.P. | Microfluidic filtering system |
| JP6447597B2 (ja) * | 2016-09-08 | 2019-01-09 | シンフォニアテクノロジー株式会社 | バッファタンクおよび培養システム |
| DE102017110482A1 (de) | 2017-05-15 | 2018-11-15 | Sartorius Stedim Biotech Gmbh | Filtrationsmodul bzw. Reinigungsmodul für modulares Filtrationssystem |
| CN107102538A (zh) * | 2017-06-21 | 2017-08-29 | 利穗科技(苏州)有限公司 | 一种配液层析系统中的流量校正方法 |
| EP3431168A1 (en) * | 2017-07-19 | 2019-01-23 | Bayer Aktiengesellschaft | Élimination de médicament non lié après couplage conjugué anticorps-médicament |
| DE102017127020A1 (de) | 2017-11-16 | 2019-05-16 | Sartorius Stedim Biotech Gmbh | Verfahren zum Filtrieren eines großen Volumens eines Mediums mit einer vorsterilisierbaren, wenigstens teilautomatisierten Einweg-Filtrationsvorrichtung |
| DE102018004909B4 (de) * | 2018-06-19 | 2020-03-26 | Sartorius Stedim Biotech Gmbh | Modulares Prozessiersystem und Verfahren zum modularen Aufbau eines Prozessiersystems |
| CN111220429A (zh) * | 2018-11-23 | 2020-06-02 | 中国科学院大连化学物理研究所 | 一种阵列高通量蛋白质样品预处理装置 |
| EP3960281A1 (en) * | 2020-08-31 | 2022-03-02 | Brita GmbH | Method for venting a hollow fiber membrane filter and hollow fiber membrane filter device |
| CA3199735A1 (en) * | 2020-11-23 | 2022-05-27 | Chris Klopp | Filtration systems,components and methods |
| WO2022182388A1 (en) * | 2021-02-26 | 2022-09-01 | The Penn State Research Foundation | Separation apparatus and method |
| KR20230155498A (ko) * | 2021-03-08 | 2023-11-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 단일 통과 역류 정용여과를 위한 시스템 및 방법 |
| JP2025533182A (ja) * | 2022-10-10 | 2025-10-03 | アストラゼネカ・アクチエボラーグ | 灌流バイオリアクタ接線流濾過 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3582488A (en) * | 1965-06-25 | 1971-06-01 | Rashid A Zeineh | Method and apparatus for buffering,dialysis and concentrating biological fluid specimens |
| US3827561A (en) * | 1972-09-20 | 1974-08-06 | Milton Roy Co | Deaerator for dialysis system |
| DE2801018A1 (de) * | 1978-01-11 | 1979-07-19 | Jenaer Glaswerk Schott & Gen | Hochdruck-ultrafiltrations-anlage |
| US4670152A (en) * | 1984-02-27 | 1987-06-02 | Omnis Surgical Inc. | Priming system for ultrafiltration unit |
| US4963264A (en) * | 1985-06-10 | 1990-10-16 | The Standard Oil Company | Process for selective dialysis using polymeric affinity adsorbents and size selective membranes |
| DE4234728A1 (de) * | 1992-10-15 | 1994-04-21 | Peter Prof Dr Bartholmes | Verfahren für die Gewinnung und die Umpufferung und/oder Einengung von gelösten Makromolekülen eines Makromolekülegemisches |
| US5932103A (en) * | 1995-02-13 | 1999-08-03 | Aksys, Ltd. | Withdrawal of priming fluid from extracorporeal circuit of hemodialysis machines or the like |
| US5591344A (en) * | 1995-02-13 | 1997-01-07 | Aksys, Ltd. | Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof |
| RU2112747C1 (ru) * | 1997-06-18 | 1998-06-10 | Владимир Яковлевич Микиртычев | Способ очистки воды и мембранная установка для его осуществления |
| IT1295216B1 (it) * | 1997-10-07 | 1999-05-04 | Bellco Spa | Apparecchiatura per trattamento di dialisi. |
| US5951870A (en) * | 1997-10-21 | 1999-09-14 | Dsu Medical Corporation | Automatic priming of blood sets |
| JP4903311B2 (ja) * | 1999-04-30 | 2012-03-28 | チルドレンズ ホスピタル メディカル センター | モニタされた患者パラメータにもとづく血液濾過システムおよび方法、血液濾過の監視制御装置および血液濾過用ポンプの適応制御 |
| EP1351756B1 (en) * | 2000-12-20 | 2013-07-24 | Nephros, Inc. | Multistage hemodiafiltration/hemofiltration apparatus |
| ITBO20020119A1 (it) * | 2002-03-08 | 2003-09-08 | Bellco Spa | Gruppo per il controllo e la variazione del flusso di una soluzione dializzante in un processo di emodiafiltrazione |
| US20040167320A1 (en) * | 2003-02-24 | 2004-08-26 | Couto Daniel E. | Methods of tangential flow filtration and an apparatus therefore |
| US7384549B2 (en) | 2005-12-29 | 2008-06-10 | Spf Innovations, Llc | Method and apparatus for the filtration of biological solutions |
| EP2069387A4 (en) | 2006-06-14 | 2011-02-02 | Glaxosmithkline Llc | METHODS OF PURIFYING ANTIBODIES USING HYDROXYAPATITE CERAMIC |
| NL2000799C2 (nl) * | 2007-08-08 | 2009-02-10 | Prime Water Internat N V | Inrichting voor het filtreren van verontreinigd water. |
| DE102007044922B4 (de) * | 2007-09-20 | 2012-04-19 | Manfred Völker | Filtermodul und dessen Aneinanderreihung zu einem Filtersystem |
| DE102007052571A1 (de) * | 2007-11-03 | 2009-05-07 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Vorrichtung zur Überwachung der Zufuhr von Substitutionsflüssigkeit während einer extrakorporalen Blutbehandlung |
| CN103298542A (zh) * | 2010-10-15 | 2013-09-11 | 艾克塞勒雷克斯公司 | 大容量的一次性超滤系统和方法 |
| JP2013544524A (ja) | 2010-12-06 | 2013-12-19 | ターポン バイオシステムズ,インコーポレイテッド | 生物学的生成物の連続プロセス法 |
| CN102703550B (zh) | 2012-03-06 | 2014-05-14 | 南京工业大学 | 一种从蜡样芽孢杆菌高密度发酵液中提取蛋白质的方法 |
| WO2015007596A1 (en) * | 2013-07-15 | 2015-01-22 | Gambro Lundia Ab | Relative pump calibration for ultrafiltration control in a dialysis apparatus |
| JP6146831B2 (ja) * | 2014-01-16 | 2017-06-14 | 国立大学法人九州大学 | 低分子量成分の除去方法 |
-
2014
- 2014-02-17 EP EP14155338.8A patent/EP2907565A1/de not_active Withdrawn
-
2015
- 2015-02-11 AR ARP150100390A patent/AR099462A1/es active IP Right Grant
- 2015-02-13 SG SG11201606341PA patent/SG11201606341PA/en unknown
- 2015-02-13 WO PCT/EP2015/053060 patent/WO2015121403A1/de not_active Ceased
- 2015-02-13 EP EP15705577.3A patent/EP3107641A1/de not_active Withdrawn
- 2015-02-13 CA CA2939579A patent/CA2939579A1/en not_active Abandoned
- 2015-02-13 AU AU2015217006A patent/AU2015217006B2/en not_active Ceased
- 2015-02-13 NZ NZ721864A patent/NZ721864A/en unknown
- 2015-02-13 CN CN201580009079.7A patent/CN106255542B/zh not_active Expired - Fee Related
- 2015-02-13 KR KR1020167021971A patent/KR102285176B1/ko not_active Expired - Fee Related
- 2015-02-13 BR BR112016018536-6A patent/BR112016018536A2/pt active Search and Examination
- 2015-02-13 RU RU2016137161A patent/RU2676639C2/ru active
- 2015-02-13 US US15/119,126 patent/US10421042B2/en not_active Expired - Fee Related
- 2015-02-13 TW TW104104908A patent/TWI632156B/zh not_active IP Right Cessation
- 2015-02-13 MX MX2016010542A patent/MX380369B/es unknown
- 2015-02-13 JP JP2016569012A patent/JP6605504B2/ja not_active Expired - Fee Related
-
2016
- 2016-07-18 ZA ZA2016/04982A patent/ZA201604982B/en unknown
- 2016-08-01 IL IL247033A patent/IL247033B/en active IP Right Grant
- 2016-08-16 SA SA516371679A patent/SA516371679B1/ar unknown
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