JP2017510627A5 - - Google Patents

Download PDF

Info

Publication number
JP2017510627A5
JP2017510627A5 JP2016574516A JP2016574516A JP2017510627A5 JP 2017510627 A5 JP2017510627 A5 JP 2017510627A5 JP 2016574516 A JP2016574516 A JP 2016574516A JP 2016574516 A JP2016574516 A JP 2016574516A JP 2017510627 A5 JP2017510627 A5 JP 2017510627A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
antagonist
mcam
composition according
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016574516A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017510627A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2015/051785 external-priority patent/WO2015136468A1/en
Publication of JP2017510627A publication Critical patent/JP2017510627A/ja
Publication of JP2017510627A5 publication Critical patent/JP2017510627A5/ja
Pending legal-status Critical Current

Links

JP2016574516A 2014-03-13 2015-03-12 多発性硬化症の併用治療 Pending JP2017510627A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461952835P 2014-03-13 2014-03-13
US61/952,835 2014-03-13
US201462023577P 2014-07-11 2014-07-11
US62/023,577 2014-07-11
PCT/IB2015/051785 WO2015136468A1 (en) 2014-03-13 2015-03-12 Combination treatment for multiple sclerosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020019355A Division JP2020100631A (ja) 2014-03-13 2020-02-07 多発性硬化症の併用治療

Publications (2)

Publication Number Publication Date
JP2017510627A JP2017510627A (ja) 2017-04-13
JP2017510627A5 true JP2017510627A5 (enExample) 2018-04-19

Family

ID=52737375

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016574516A Pending JP2017510627A (ja) 2014-03-13 2015-03-12 多発性硬化症の併用治療
JP2020019355A Pending JP2020100631A (ja) 2014-03-13 2020-02-07 多発性硬化症の併用治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020019355A Pending JP2020100631A (ja) 2014-03-13 2020-02-07 多発性硬化症の併用治療

Country Status (6)

Country Link
US (1) US20170002077A1 (enExample)
EP (1) EP3116910A1 (enExample)
JP (2) JP2017510627A (enExample)
KR (1) KR20170052526A (enExample)
CA (1) CA2938945A1 (enExample)
WO (1) WO2015136468A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI595007B (zh) 2012-09-10 2017-08-11 Neotope Biosciences Ltd 抗mcam抗體及相關使用方法
PT3116911T (pt) 2014-03-12 2019-09-04 Prothena Biosciences Ltd Anticorpos anti-mcam e métodos de utilização associados
JP2017514458A (ja) 2014-03-12 2017-06-08 プロセナ バイオサイエンシーズ リミテッド Lg4−5に対して特異的な抗−ラミニン4抗体
WO2017134178A1 (en) * 2016-02-05 2017-08-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Imaging method for predicting the onset of multiple sclerosis
WO2017149513A1 (en) * 2016-03-03 2017-09-08 Prothena Biosciences Limited Anti-mcam antibodies and associated methods of use
WO2017153955A1 (en) * 2016-03-09 2017-09-14 Prothena Biosciences Limited Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
CA3082368A1 (en) * 2017-11-09 2019-05-16 Sapporo Medical University Medicine for tissue regeneration, and preparation method therefor
CA3147044A1 (en) * 2019-07-11 2021-01-14 Tavotek Biotherapeutics (Hong Kong) Limited Agents that interfere with thymic stromal lymphopoietin (tslp)-receptor signaling
WO2024249568A1 (en) 2023-05-30 2024-12-05 Paragon Therapeutics, Inc. Alpha4beta7 integrin antibody compositions and methods of use
CN121889424A (zh) 2023-08-14 2026-04-17 派拉冈医疗公司 α4β7整联蛋白结合蛋白及使用方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US5834597A (en) 1996-05-20 1998-11-10 Protein Design Labs, Inc. Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
JP2001517245A (ja) 1997-05-29 2001-10-02 メルク エンド カンパニー インコーポレーテッド 細胞接着阻害薬としてのビアリールアルカン酸類
IL133639A0 (en) 1997-07-31 2001-04-30 Elan Pharm Inc Dipeptide and related compounds which inhibit leukocyte adhesion mediated by vla-4
KR20010022411A (ko) 1997-07-31 2001-03-15 진 엠. 듀발 Vla-4에 의해 매개되는 백혈구 부착을 억제하는 치환된페닐알라닌계의 화합물
WO1999006436A1 (en) 1997-07-31 1999-02-11 Elan Pharmaceuticals, Inc. Benzyl compounds which inhibit leukocyte adhesion mediated by vla-4
EP1005445B1 (en) 1997-08-22 2004-05-26 F. Hoffmann-La Roche Ag N-alkanoylphenylalanine derivatives
MY153569A (en) 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
US6521626B1 (en) 1998-03-24 2003-02-18 Celltech R&D Limited Thiocarboxamide derivatives
PL343770A1 (en) 1998-04-16 2001-09-10 Texas Biotechnology Corp N,n-disubstituted amides that inhibit the binding of integrins to their receptors
GB9811969D0 (en) 1998-06-03 1998-07-29 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9821406D0 (en) 1998-10-01 1998-11-25 Celltech Therapeutics Ltd Chemical compounds
NZ513144A (en) 1999-02-05 2003-05-30 Samsung Electronics Co Ltd Image texture retrieving method and apparatus thereof
ATE383153T1 (de) 1999-05-07 2008-01-15 Encysive Pharmaceuticals Inc Carbonsäurederivate die die bindung von integrinen an ihre rezeptoren hemmen
AU6909300A (en) 1999-08-20 2001-03-19 Merck & Co., Inc. Substituted ureas as cell adhesion inhibitors
WO2002008206A1 (en) 2000-07-21 2002-01-31 Elan Pharmaceuticals, Inc. 3-amino-2-(4-aminocarbonyloxy)phenyl-propionic acid derivatives as alpha-4- integrin inhibitors
US7192931B2 (en) * 2000-10-12 2007-03-20 Neuren Pharmaceuticals Ltd. Treatment of demyelinating diseases
CN100522242C (zh) * 2001-02-19 2009-08-05 默克专利有限公司 具有降低的免疫原性的人工蛋白质
MXPA05000511A (es) 2001-07-12 2005-09-30 Jefferson Foote Anticuepros super humanizados.
CA2460149A1 (en) 2001-09-12 2003-03-27 Kaken Pharmaceutical Co., Ltd. 2-phenyl-3-heteroarylpropionic acid derivative or salt thereof and medicine containing the same
CA2514117A1 (en) * 2003-01-24 2004-08-12 Elan Pharmaceuticals, Inc. Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
NZ595526A (en) * 2007-06-14 2013-03-28 Biogen Idec Inc Pharmaceutical composition comprising a vla-4 binding antibody, a phosphate buffer and a surfactant
AU2011272941B2 (en) * 2010-06-30 2014-05-29 Compugen Ltd. C10RF32 for the treatment of multiple sclerosis, rheumatoid arthritis and other autoimmune disorders
WO2012170071A1 (en) 2011-06-06 2012-12-13 Elan Pharmaceuticas, Inc Mcam antagonists and methods of treatment
TWI595007B (zh) * 2012-09-10 2017-08-11 Neotope Biosciences Ltd 抗mcam抗體及相關使用方法

Similar Documents

Publication Publication Date Title
JP2017510627A5 (enExample)
CY1120414T1 (el) Αντισωματα που συνδεονται me οχ40 και οι χρησεις τους
HRP20241447T1 (hr) Bispecifična inhibitor antitijela kontrolnih točaka
RU2018133708A (ru) Антитела, обладающие специфичностью к btla, и их использование
HRP20190643T1 (hr) Protutijela protiv dkk-1
HRP20201729T1 (hr) Antitijela protiv aktivina a i njihova primjena
EA201991577A1 (ru) Новые антитела против рецептора трансферрина человека, способные преодолевать гематоэнцефалический барьер
RU2018102798A (ru) Антитела к фактору xi и способы их применения
RU2018119686A (ru) Антитела и фрагменты антител для сайт-специфического конъюгирования
JP2014205674A5 (enExample)
WO2016207304A8 (en) Monoclonal anti-il-1racp antibodies
HRP20230844T1 (hr) Anti-cd3 antitijela, bispecifične molekule koje vežu antigen koji veže cd3 i cd20, i njihove upotrebe
JP2016536322A5 (enExample)
JP2014518883A5 (enExample)
PH12015501505B1 (en) Antibodies that bind to tl1a and their uses
JP2016029056A5 (enExample)
ES2776179T3 (es) Anticuerpos dirigidos contra determinantes de la superficie de S. aureus
ME02678B (me) Antitijela na ox-40 i postupci njihove primjene
JP2016183153A5 (enExample)
PH12017500699A1 (en) Antibodies that bind to ccr6 and their uses
HRP20220069T1 (hr) Antitijelo
JP2016530223A5 (enExample)
JP2015509960A5 (enExample)
JP2014527396A5 (enExample)
JP2017511152A5 (enExample)