JP2017510575A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017510575A5 JP2017510575A5 JP2016558161A JP2016558161A JP2017510575A5 JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5 JP 2016558161 A JP2016558161 A JP 2016558161A JP 2016558161 A JP2016558161 A JP 2016558161A JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- fusion polypeptide
- disease
- syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461954437P | 2014-03-17 | 2014-03-17 | |
| US61/954,437 | 2014-03-17 | ||
| PCT/JP2015/058645 WO2015141862A1 (en) | 2014-03-17 | 2015-03-16 | Antibody-fynomer conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017510575A JP2017510575A (ja) | 2017-04-13 |
| JP2017510575A5 true JP2017510575A5 (https=) | 2017-08-10 |
| JP6345800B2 JP6345800B2 (ja) | 2018-06-20 |
Family
ID=54144822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558161A Active JP6345800B2 (ja) | 2014-03-17 | 2015-03-16 | 抗体−フィノマー複合体 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10323095B2 (https=) |
| EP (1) | EP3119885B1 (https=) |
| JP (1) | JP6345800B2 (https=) |
| KR (1) | KR102473544B1 (https=) |
| CN (1) | CN106211782B (https=) |
| AU (1) | AU2015232352B2 (https=) |
| CA (1) | CA2942546C (https=) |
| DK (1) | DK3119885T3 (https=) |
| ES (1) | ES2881602T3 (https=) |
| HU (1) | HUE055424T2 (https=) |
| MX (1) | MX374483B (https=) |
| PH (1) | PH12016501816A1 (https=) |
| PL (1) | PL3119885T3 (https=) |
| PT (1) | PT3119885T (https=) |
| RU (1) | RU2732226C2 (https=) |
| TW (1) | TWI674274B (https=) |
| WO (1) | WO2015141862A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10513537B2 (en) | 2016-05-11 | 2019-12-24 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| WO2017194592A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of storing a separation matrix |
| WO2017194593A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US10722589B2 (en) * | 2017-04-03 | 2020-07-28 | Covagen Ag | FGFR3 binding molecules |
| US20190100587A1 (en) | 2017-10-02 | 2019-04-04 | Covagen Ag | IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS |
| US20190153096A1 (en) | 2017-10-02 | 2019-05-23 | Covagen Ag | Cd3/cd33 bispecific binding molecules |
| US20220249679A1 (en) * | 2018-10-02 | 2022-08-11 | Mitsubishi Tanabe Pharma Corporation | Bi-specific binding agents targeting syndecan-1 and fibroblast growth factor receptor |
| CN119350498A (zh) | 2018-12-28 | 2025-01-24 | 四川科伦博泰生物医药股份有限公司 | 一种抗体及其用途 |
| KR20210151774A (ko) | 2019-04-16 | 2021-12-14 | 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 | 항-FXI/FXIa 항체 및 그 용도 |
| WO2021063201A1 (zh) | 2019-09-30 | 2021-04-08 | 四川科伦博泰生物医药股份有限公司 | 抗pd-1抗体及其用途 |
| AU2020400221A1 (en) | 2019-12-13 | 2022-05-19 | Harbour Biomed (Shanghai) Co., Ltd. | Anti-TSLP antibody and uses thereof |
| CN115715202B (zh) | 2020-05-15 | 2025-11-04 | 四川科伦博泰生物医药股份有限公司 | 抗体药物缀合物及其制备方法和用途 |
| US20240002504A1 (en) | 2020-10-26 | 2024-01-04 | Akeso Biopharma, Inc. | Anti-tigit antibody, and pharmaceutical composition and use thereof |
| JP7691668B2 (ja) | 2020-12-31 | 2025-06-12 | 諾納生物（蘇州）有限公司 | ヒトｌｉｆｒ抗原結合タンパク質、その製造方法及び応用 |
| WO2022157493A1 (en) | 2021-01-21 | 2022-07-28 | Eusa Pharma (Uk) Limited | Method for treating il-6 associated histiocytic and lymphoproliferative disorders |
| WO2022188652A1 (zh) | 2021-03-09 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | Ror1结合蛋白及其用途 |
| IL310217A (en) | 2021-07-23 | 2024-03-01 | Akeso Biopharma Inc | Pharmaceutical composition and use |
| WO2023044483A2 (en) | 2021-09-20 | 2023-03-23 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| US20250034559A1 (en) | 2021-11-17 | 2025-01-30 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| CN114181310B (zh) | 2022-02-14 | 2022-07-05 | 中山康方生物医药有限公司 | 抗tigit抗体、其药物组合物及用途 |
| CN114853890B (zh) | 2022-03-16 | 2023-04-28 | 沈阳三生制药有限责任公司 | 一种prlr抗原结合蛋白及其制备方法和应用 |
| CN116925222A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗pvrig抗体、其药物组合物及用途 |
| CN116925233A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗tigit-抗pvrig双特异性抗体、其药物组合物及用途 |
| WO2023220695A2 (en) | 2022-05-13 | 2023-11-16 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| WO2024228389A1 (ja) * | 2023-05-02 | 2024-11-07 | 田辺三菱製薬株式会社 | 対象における二重特異性融合ポリペプチドの有効性を予測するための方法 |
| IL326700A (en) * | 2023-09-11 | 2026-04-01 | Hoffmann La Roche | Multispecific fusion proteins targeting angiogenic and inflammatory factors |
| WO2025122634A1 (en) | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| WO2025224095A1 (en) | 2024-04-22 | 2025-10-30 | Recordati Netherlands Bv | Use of inhibitors of il-6 or il-6r for treating graft versus host disease in a subject |
| PL448731A1 (pl) * | 2024-05-31 | 2025-12-01 | Celon Pharma Spółka Akcyjna | Przeciwciała bispecyficzne anty–IL-17A i anty-IL-6 oraz ich zastosowanie w terapii, zwłaszcza w leczeniu chorób immunologicznych |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| ES2595638T3 (es) * | 2007-09-26 | 2017-01-02 | Chugai Seiyaku Kabushiki Kaisha | Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR |
| MX2010012031A (es) | 2008-05-13 | 2011-01-20 | Novimmune Sa | Anticuerpos anti-il-6/il-6r y metodos de uso de los mismos. |
| CA2726087A1 (en) * | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Dual variable domain immunoglobulins and uses thereof |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| MX2012002428A (es) * | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| AR080428A1 (es) | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
| US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| EP2597102A1 (en) | 2011-11-25 | 2013-05-29 | Covagen AG | A novel fusion protein comprising an antibody light chain and a polypeptide binding to IL-17 |
| EP2791170A1 (en) | 2011-12-16 | 2014-10-22 | Synthon Biopharmaceuticals B.V. | Compounds and methods for treating inflammatory diseases |
| EP2638916A1 (en) * | 2012-03-16 | 2013-09-18 | Covagen AG | Novel binding molecules with antitumoral activity |
| JP6325463B2 (ja) | 2012-03-16 | 2018-05-16 | コヴァジェン アクチェン ゲゼルシャフト | 抗腫瘍活性を有する新規結合分子 |
| EP2711016A1 (en) * | 2012-09-21 | 2014-03-26 | Covagen AG | Novel IL-17A binding molecules and medical uses thereof |
-
2015
- 2015-03-16 CA CA2942546A patent/CA2942546C/en active Active
- 2015-03-16 JP JP2016558161A patent/JP6345800B2/ja active Active
- 2015-03-16 TW TW104108275A patent/TWI674274B/zh active
- 2015-03-16 KR KR1020167028719A patent/KR102473544B1/ko active Active
- 2015-03-16 WO PCT/JP2015/058645 patent/WO2015141862A1/en not_active Ceased
- 2015-03-16 PL PL15765900T patent/PL3119885T3/pl unknown
- 2015-03-16 MX MX2016012010A patent/MX374483B/es active IP Right Grant
- 2015-03-16 CN CN201580014271.5A patent/CN106211782B/zh active Active
- 2015-03-16 HU HUE15765900A patent/HUE055424T2/hu unknown
- 2015-03-16 DK DK15765900.4T patent/DK3119885T3/da active
- 2015-03-16 PT PT157659004T patent/PT3119885T/pt unknown
- 2015-03-16 US US15/126,551 patent/US10323095B2/en active Active
- 2015-03-16 ES ES15765900T patent/ES2881602T3/es active Active
- 2015-03-16 RU RU2016140572A patent/RU2732226C2/ru active
- 2015-03-16 AU AU2015232352A patent/AU2015232352B2/en active Active
- 2015-03-16 EP EP15765900.4A patent/EP3119885B1/en active Active
-
2016
- 2016-09-16 PH PH12016501816A patent/PH12016501816A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017510575A5 (https=) | ||
| RU2016140572A (ru) | Конъюгаты антитело-финомер | |
| JP2021507690A5 (https=) | ||
| JP2011526792A5 (https=) | ||
| CN101484472B (zh) | 改善的sgp130Fc二聚体 | |
| JP2019058197A5 (https=) | ||
| JP2020521458A5 (https=) | ||
| RU2012111597A (ru) | Новые il-17-связывющие соединения и их медицинское применение | |
| JP2020193195A5 (https=) | ||
| JP2015511637A5 (https=) | ||
| JP2014513953A5 (https=) | ||
| FI3250610T3 (fi) | Fcrn-vasta-aineita ja menetelmiä niiden käyttämiseksi | |
| JP2012516158A5 (https=) | ||
| JP2016510736A5 (https=) | ||
| JP2010511056A5 (https=) | ||
| ES2822431T3 (es) | Polipéptidos de unión a IL-17A | |
| EA035973B9 (en) | Amino acid sequences directed against il-17a, il-17f and/or il-17a/f and polypeptides comprising the same | |
| JP2012517818A5 (https=) | ||
| RU2011102579A (ru) | СТАБИЛЬНЫЕ И РАСТВОРИМЫЕ АНТИТЕЛА, ИНГИБИРУЮЩИЕ TNFα | |
| FI3697810T3 (fi) | Icos-ligandin variantin immunomodulatorisia proteiineja ja niihin liittyviä koostumuksia ja menetelmiä | |
| JP2014511844A5 (https=) | ||
| JP2022507741A5 (https=) | ||
| WO2012088006A1 (en) | Fibronectin based scaffold domain proteins that bind il-23 | |
| MX2013001107A (es) | Agonistas y antagonistas del receptor tipo i de il-1 quimerico. | |
| HRP20050375B1 (hr) | Taljeni azol-pirimidin derivati |