JP2017509672A5 - - Google Patents
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- Publication number
- JP2017509672A5 JP2017509672A5 JP2016560467A JP2016560467A JP2017509672A5 JP 2017509672 A5 JP2017509672 A5 JP 2017509672A5 JP 2016560467 A JP2016560467 A JP 2016560467A JP 2016560467 A JP2016560467 A JP 2016560467A JP 2017509672 A5 JP2017509672 A5 JP 2017509672A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- compound
- salt
- medicament
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461973366P | 2014-04-01 | 2014-04-01 | |
| US61/973,366 | 2014-04-01 | ||
| PCT/US2015/023954 WO2015153814A1 (en) | 2014-04-01 | 2015-04-01 | Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017509672A JP2017509672A (ja) | 2017-04-06 |
| JP2017509672A5 true JP2017509672A5 (enExample) | 2018-01-25 |
| JP6557253B2 JP6557253B2 (ja) | 2019-08-07 |
Family
ID=54241267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016560467A Expired - Fee Related JP6557253B2 (ja) | 2014-04-01 | 2015-04-01 | 抗腫瘍化合物としてのシグマ−２受容体リガンド薬物結合体、その合成法及び使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US10087175B2 (enExample) |
| EP (1) | EP3126356B1 (enExample) |
| JP (1) | JP6557253B2 (enExample) |
| CN (1) | CN106459011B (enExample) |
| AU (2) | AU2015240775B2 (enExample) |
| CA (1) | CA2944069C (enExample) |
| ES (1) | ES2743701T3 (enExample) |
| WO (1) | WO2015153814A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10087175B2 (en) * | 2014-04-01 | 2018-10-02 | Washington University | Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof |
| US11175296B2 (en) * | 2016-10-26 | 2021-11-16 | Washington University | Methods of diagnosing and treating cancer comprising ME1 |
| EP3630089A4 (en) * | 2017-05-24 | 2021-06-09 | Ferro Therapeutics, Inc. | PROCEDURE FOR CANCER THERAPY |
| US11541116B1 (en) | 2022-01-07 | 2023-01-03 | Kojin Therapeutics, Inc. | Methods and compositions for inducing ferroptosis in vivo |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7358262B2 (en) * | 2003-01-29 | 2008-04-15 | Whitehead Institute For Biomedical Research | Identification of genotype-selective anti-tumor agents |
| US20070161644A1 (en) * | 2005-01-25 | 2007-07-12 | Stockwell Brent R | Erastin analogs and uses thereof |
| JP5139083B2 (ja) | 2005-01-25 | 2013-02-06 | プロレキシーズ ファーマシューティカルズ インコーポレイテッド | 抗腫瘍剤としてのキノキサリン誘導体 |
| WO2006081337A2 (en) * | 2005-01-25 | 2006-08-03 | Whitehead Institute For Biomedical Research | Erastin analogues and their uses for killing cancer cells |
| WO2006130426A2 (en) | 2005-05-27 | 2006-12-07 | Kemia, Inc. | Modulators of ccr-5 activity |
| BRPI0620264A2 (pt) | 2005-12-22 | 2011-11-08 | Prolexys Pharmaceuticals Inc | quinazolonas aril-substituìdas e sua utilização |
| WO2008013987A2 (en) * | 2006-07-27 | 2008-01-31 | Prolexys Pharmaceuticals, Inc. | N-alkyl substituted piperazinylmethylquinazolinones and azepanylmethylquinazolinones |
| WO2008042926A1 (en) | 2006-10-04 | 2008-04-10 | Bristol-Myers Squibb Company | Cyclic modulators of chemokine receptor activity |
| US8143222B2 (en) | 2007-10-22 | 2012-03-27 | Washington University | Modular platform for targeted therapeutic delivery |
| US10087175B2 (en) | 2014-04-01 | 2018-10-02 | Washington University | Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof |
-
2015
- 2015-04-01 US US15/301,188 patent/US10087175B2/en active Active
- 2015-04-01 CN CN201580029187.0A patent/CN106459011B/zh active Active
- 2015-04-01 ES ES15773524T patent/ES2743701T3/es active Active
- 2015-04-01 CA CA2944069A patent/CA2944069C/en active Active
- 2015-04-01 JP JP2016560467A patent/JP6557253B2/ja not_active Expired - Fee Related
- 2015-04-01 WO PCT/US2015/023954 patent/WO2015153814A1/en not_active Ceased
- 2015-04-01 EP EP15773524.2A patent/EP3126356B1/en active Active
- 2015-04-01 AU AU2015240775A patent/AU2015240775B2/en active Active
-
2018
- 2018-08-24 US US16/111,842 patent/US10344029B2/en active Active
-
2019
- 2019-01-18 AU AU2019200353A patent/AU2019200353B2/en active Active
- 2019-05-30 US US16/426,791 patent/US10975069B2/en active Active
-
2021
- 2021-03-09 US US17/196,286 patent/US20210221805A1/en not_active Abandoned
-
2024
- 2024-09-10 US US18/830,098 patent/US20250145617A1/en active Pending
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